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您的检索式：作者名="Koshi Sato"
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| 1 | Effect of atrial natriuretic peptide on ischemia-reperfusion injury in a porcine total hepatic vascular exclusion model显示文摘AIM: To evaluate the effect of ANP on warm I/R injury in a porcine THVE model. METHODS: Miniature pigs (mini-pigs) weighing 16-24 kg were observed for 120 min after reperfusion following 120 min of THVE. The animals were divided into two groups. ANP (0.1 μg/kg per min) was administered to the ANP group (n = 7), and vehicle was administered to the control group (n = 7). Either vehicle or ANP was intravenously administered from 30 min before the THVE to the end of the experiment. Arterial blood was collected to measure AST, LDH, and TNF-α. Hepatic tissue blood ? ow (HTBF) was also measured. Liver specimens were harvested for p38 MAPK analysis and histological study. Those results were compared between the two groups. RESULTS: The AST and LDH levels were lower in the ANP group than in the control group; the AST levels were signifi cantly different between the two groups (60 min: 568.7 ± 113.3 vs 321.6 ± 60.1, P = 0.038 < 0.05, 120 min: 673.6 ± 148.2 vs 281.1 ± 44.8, P = 0.004 < 0.01). No signifi cant difference was observed in the TNF-α levels between the two groups. HTBF was higher in the ANP group, but the difference was not signif icant. A signifi cantly higher level of phosphorylated p38 MAPK was observed in the ANP group compared to the controlgroup (0 min: 2.92 ± 1.1 vs 6.38 ± 1.1, P = 0.011 < 0.05).Histological tissue damage was milder in the ANP group than in the control group. CONCLUSION: Our results show that ANP has a protective role in I/R injury with p38 MAPK activation in a porcine THVE model. | Katsumi Kobayashi Kiyohiro Oshima Masato Muraoka Takahiko Akao Osamu Totsuka Hisashi Shimizu Hiroaki Sato Kazumi Tanaka Kenjiro Konno Koshi Matsumoto Izumi Takeyoshi | 2007 | World Journal of Gastroenterology2007，13，25： | 4 |
| 2 | Low friction in self-mated silicon carbide tribosystem using nanodiamond as lubricating additive in water显示文摘Nanodiamond particles(NDPs)have been considered as a potential lubricant additive to various tribological applications,such as water lubrication systems.In this study,the tribological properties of silicon carbide(SiC)lubricated by NDPs dispersed in water are investigated utilizing the ball-on-disk tribometer.It is found that the slight addition of NDP to water(i.e.,0.001 wt%)can distinctly accelerate the running-in process,which is necessary to achieve a friction coefficient(μ)as low as 0.01.This study also discusses two NDP functional terminations—hydroxyl and carboxyl.It is demonstrated that the use of carboxyl-terminated NDP over a wide range of concentration(0.001 wt%-1 wt%)yields a low friction force.In contrast,the ideal effective concentration of hydroxyl-terminated NDP is considerably limited because agglomeration in this material is more probable to occur than in the former.Meanwhile,when utilizing NDPs,the input friction energy(P_(in),defined as the product of sliding speed and applied load)is found to have an essential function.Several sliding tests were implemented at various P_(in) values(50-1,500 mW)using carboxyl-terminated water-dispersed NDPs.It was observed that theμand wear decreased with increasing P_(in) when 200 mW | Xudong WANG Hirotsuna SATO Koshi ADACHI | 2021 | Friction2021，9，3： | 1 |
| 3 | Cause of Death in Renal Transplant Patients: A Comparison Between Aza- thioprine and Ciclosporin显示文摘 | Koshi Sato Kensho Ogawa Osamu Onumata | 2001 | 11( 10 ): 133-1342001，11，10： | 1 |
| 4 | Cervical vertebral bone age in girls显示文摘 | Toshinori Mito Koshi Sato Hideo Mitani | 2002 | Am J Orthod Dentfacial Orthop2002，122，4： | 1 |
| 5 | Pancreatographic Classification of Pancreatic Ductal Injuries Caused by Blunt Injury to the Pancreas显示文摘 | Tsunemasa Takishima Mitsuhiro Hirata Yuichi Kataoka Yasushi Asari Koshi Sato Takashi Ohwada Akira Kakita | 2000 | The Journal of Trauma: Injury Infection and Critical Care2000，，4： | 1 |
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