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| 1 | Impact of polyethylene glycol 400/propylene glycol/hydroxypropyl-guar and 0.1%sodium hyaluronate on postoperative discomfort following cataract extraction surgery:a comparative study显示文摘Background:Universal postoperative guidelines for cataract extraction surgery are yet to be introduced.Artificial tears are gaining popularity as an additional integral component of the postoperative regime.The primary objective of this study was to explore the impact of two prevalent artificial tear preparations on postoperative discomfort following cataract extraction surgery.Methods:A total of 180 patients that underwent cataract extraction surgery were randomly divided into three groups according to their postoperative regime:a)Study group 1(SG1)received a fixed combination of tobramycin and dexamethasone(FCTD)quid for 3 weeks and,additionally polyethylene glycol 400/propylene glycol/hydroxypropyl-guar quid,for 6 weeks,b)Study group 2(SG2)received FCTD quid for 3 weeks and,additionally 0.1%sodium hyaluronate provided in the COMOD^(®)device quid,for 6 weeks,and,c)Control Group(CG)received only FCTD quid for 3 weeks.The following indexes were evaluated at three postoperative checkpoints:1)Subjective discomfort index(SDI)derived from four direct 10-scale Likert-type questions that were addressed to the patient and pertained to:a)foreign body sensation(FBS),b)blinking discomfort(BD),c)stinging sensation(SS),d)tearing sensation(TS),2)Tear break-up time(TBUT),3)Central corneal thickness(CCT)and,4)Central Corneal Sensitivity(CCS).Results:Both groups showed increased CCT values at the first examination point and reduced CCS values at all examination points.Furthermore,both SGs had better TBUT times at all examination points compared to CG(CG:8.86±1.08,SG1:9.59±1.45,CG2:9.45±1.33,p<0.05).BD was significantly better in both SGs only at the 1^(st) week of examination,while SDI values were better until the 3^(rd) week and only borderline better at 6^(th) week.Lastly,no significant differences were detected between SGs,regarding all parameters,at all examination points.Conclusion:Polyethylene glycol 400/propylene glycol/hydroxypropyl-guar and 0.1%sodium hyaluronate provided in the COMOD^(®)device seem to be equally efficient in alleviating OSD symptoms following cataract extraction surgery and any of them should be routinely added to the postoperative regime. | Georgios Labiris Panagiota Ntonti Haris Sideroudi Vassilios Kozobolis | 2017 | Eye and Vision2017，4，1： | 4 |
| 2 | Imaging of filtering blebs after implantation of the Ex-PRESS shunt with the use of the Visante optical coherence tomography显示文摘AIM: To analyze the features of the filtering blebs following implantation of the Ex-PRESS glaucoma device(model P-50) with the aid of the Visante anterior segment optical coherence tomography(AS-OCT)METHODS: Five patients with open angle glaucomas were included in the study. They all underwent implantation of the Ex-PRESS device under a scleral flap. The surgical procedure was augmented with the use of mitomycin C subconjunctivally. The filtering blebs were analyzed with the Visante AS-OCT with the scans taken along the axis of the implantation of the glaucoma device.RESULTS: All filtering blebs were graded as diffuse functioning. The morphological characteristics of the blebs were similar to those of the trabeculectomy.However the use of the Ex-PRESS implant tend to form a characteristic episcleral lake at the site of the plate of the implant. CONCLUSION: The use of the Ex-PRESS implant produces filtering blebs similar to those of the trabeculectomy with the formation of a characteristic episcleral lake at the site of the plate of the implant. | Aristeidis Konstantinidis Georgios D Panos Magdalini Triantafylla Georgios Labiris Efthimia Tsaragli Zisis Gatzioufas Vassilios Kozobolis | 2015 | International Journal of Ophthalmology(English edition)2015，8，3： | 2 |
| 3 | Photorefractive keratectomy followed by same-day corneal collagen crosslinking after intrastromal corneal ring segment implantation for pellucid marginal degeneration显示文摘 | George D. Kymionis Michael A. Grentzelos Dimitra M. Portaliou Alexandra E. Karavitaki Maria S. Krasia George K. Dranidis Vasilios P. Kozobolis | 2010 | Journal of Cataract & Refractive Surgery2010，，10： | 2 |
| 4 | Modified deep sclerectomy combined with Ex-PRESS filtration device versus trabeculectomy for primary open angle glaucoma显示文摘AIM:To compare the efficacy of modified deep sclerectomy combined with Ex-PRESS shunt versus trabeculectomy in primary open angle glaucoma. METHODS:This is a prospective cohort comparative single-center study. Forty-nine eyes of 49 patients were enrolled in the study. Patients were randomly divided into two groups. Group A(22 patients) underwent classic trabeculectomy and group B(27 patients) underwent modified deep sclerectomy combined with insertion of Ex-PRESS model P50 drainage device. RESULTS:Mean age was 69±7y in group A and 64±8y in group B(P=0.03). The mean reduction was 11.1±5.7 mm Hg in group A compared to 15.8±5.7 mm Hg in group B at 6mo(P=0.006), and 9.8±4.9 mm Hg and 15.4±4.7 mm Hg respectively at 1y(P=0.0001). Regarding the postoperative glaucoma medication, significant difference was observed between the two groups(in favour of group B) only at 6mo(P=0.017). At the end of the follow-up period complete success rate in group A was 68.2% compared to 92.6% in group B(χ~2 test, P=0.07) and qualified success rate was 100% in both groups.CONCLUSION:Modified deep sclerectomy combined with Ex-PRESS shunt may provide comparable IOP reduction with fewer complications in management of primary open angle glaucoma. | Vassilios Kozobolis Georgios D.Panos Aristeidis Konstantinidis Miguel Teus Georgios Labiris | 2017 | International Journal of Ophthalmology(English edition)2017，10，5： | 2 |
| 5 | Corneal collagen cross-linking using riboflavin and ultraviolet-A irradiation:a review of clinical and experimental studies显示文摘 | Gkika M Labiris G Kozobolis V | 2011 | Int Ophthalmol2011，31，： | 1 |
| 6 | Lower eyelid laxity in functional acquired epiphora:evaluation with quantitative scintigraphy显示文摘 | Detorakis ET Zissimopoulos A Katernellis G Drakonaki EE Ganasouli DL Kozobolis VP | 2006 | Ophthal Plast Reconstr Surg2006，22，1： | 1 |
| 7 | Lower eyelid laxity in functional acquired epiphora:evaluation with quantitative scintigraphy显示文摘 | Detorakis ET Zissimopoulos A Katernellls G Drakonaki EE Ganasouli DL Kozobolis VP | | 0，，01： | 1 |
| 8 | Selective removal of sebaceous gland carcinoma of the lower eyelid with orbital infiltration 显示文摘 | Detorakis ET Ioannakis K Giatromanolaki A Sivrtdis E Drakonaki E Kozobolis VP | 2007 | Ophthalmic Surg Lasers Imaging2007，38，5： | 1 |
| 9 | Primaiy deepsclerectomy versus primary deep sclerectomy with the use of mitomy-cin C in primary open angle glaucoma显示文摘 | Kozobolis VP Christadoulakis EV Tzanakis N | 2002 | Glaucoma2002，11，4： | 1 |
| 10 | One-year follow-up of cornea confocal microscopy after cornea crosslinking in patient with post LASIK ectasia and keratoconus 显示文摘 | Kymionis GD Diakonis VF Kalyvianaki M Portaliou D Siganos C Kozobolis VP et at | 2009 | Am J Optuholmot2009，147，5： | 1 |
| 11 | UV-A collagen cross-linking treatment of bullous keratopathy combined with corneal ulcer显示文摘 | Kozobolis V Labiris G Gkika M | 2010 | Cornea2010，29，2： | 1 |
| 12 | Retrobulbar blood flow and ophthalmic perfusion in maximum dynamic exercise显示文摘 | Kozobolis V P Detorakis E T Konstas A G | 2008 | Clin Experiment Ophthalmol2008，36，2： | 1 |
| 13 | One-Year Follow-up of Corneal Confocal Microscopy After Corneal Cross-Linking in Patients With Post Laser In Situ Keratosmileusis Ectasia and Keratoconus显示文摘 | George D. Kymionis Vasilios F. Diakonis Maria Kalyvianaki Dimitra Portaliou Charalampos Siganos Vasilios P. Kozobolis Aristophanis I. Pallikaris | 2009 | American Journal of Ophthalmology2009，，5： | 1 |
| 14 | Epidemiology of pseudoexfoliation in the island of Crete ( Greece ) 显示文摘 | Kozobolis VP Papatzanaki M Vlachonikolis IG | 1997 | Acta Ophthalmol Scand1997，75，6： | 1 |
| 15 | Primary deep sclerectomy versus primary deep sclerectomy with the use of mitomycin (2 in primary open angle glaucoma显示文摘 | Kozobolis V P (2hristodoulakis E V Tzanakis N Zacharopou- los I Pallikaris I G | 2002 | J Glaucoma2002，11，： | 1 |
| 16 | Impact of Keratoconus, Cross-Linking and Cross-Linking Combined With Photorefractive Keratectomy on Self-Reported Quality of Life显示文摘 | Georgios Labiris Athanassios Giarmoukakis Haris Sideroudi Maria Gkika Michael Fanariotis Vassilios Kozobolis | 2012 | Cornea2012，，7： | 1 |
| 17 | Retrobulbar blood flow and ophthalmic perfusion in maximum dynamic exercise显示文摘 | Kozobolis VP Detorakis ET Konstas AG | 2008 | Clin Experiment Ophthalmo12008，36，2： | 1 |
| 18 | Primary deep selerectomy versus primary deep sclerectomy with the use of mitomy- cin C in primary open-angle glaucoma 显示文摘 | Kozobolis VP Christodoulakis EV Tzanakis N | 2002 | J Glaucoma2002，11，28： | 1 |
| 19 | Retrobulbar blood flow and ophthalmic perfusion in maximum dynamic exercise显示文摘 | Kozobolis VP Detorakis ET Konstas AG | 2008 | Clin Experiment Ophthalmol2008，36，2： | 1 |
| 20 | Vision-specific quality of life in Greek glauco- ma patients显示文摘 | Labiris G Katsanos A Fanariotis M Zacharaki F Chatzoulis D Kozobolis V P | 2010 | J Glaucoma2010，19，： | 1 |
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