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| 1 | Numerical investigation into the influence of the punch shape on the mechanical behavior of pharmaceutical powders during compaction显示文摘During the production of pharmaceutical tablets using powder compaction,certain common problems can occur,such as sticking,tearing,cutting,and lamination.In the past,the compressibility of the powder was calculated only along the axis of the device;consequently,critical areas of the material throughout the volume could not be identified.Therefore,finite element method(FEM) can be used to predict these defects in conjunction with the use of an appropriate constitutive model.This article summarizes the current research in the field of powder compaction,describes the Drucker-Prager Cap model calibration procedure and its implementation in FEM,and also examines the mechanical behavior of powder during compaction.In addition,the mechanical behavior of pharmaceutical powders in relation to changes in friction at the wall of the system is examined,and the dependence of lubrication effect on the geometry of the compaction space is also investigated.The influence of friction on the compaction process for the flat-face,flat-face radius edge,and standard convex tablets is examined while highlighting how the effects of friction change depending on the shape of these tablets. | Alexander Krok Marin Peciar Roman Fekete | 2014 | Particuology2014，12，5： | 3 |
| 2 | Impact of the Hepatopulmonary Syndrome MELD Exception Policy on Outcomes of Patients After Liver Transplantation: An Analysis of the UNOS Database显示文摘 | David S. Goldberg Karen Krok Sachin Batra James F. Trotter Steven M. Kawut Michael B. Fallon | 2014 | Gastroenterology2014，，： | 1 |
| 3 | Non-contact AFM investigation of influence of freezing process on the surface structure of potato starch granule显示文摘 | Krok F Szymonska J Tomasik P | 2000 | Applied Surface Science2000，157，4： | 1 |
| 4 | A meta-analysis of the placebo rates of remission and response in clinical trials of active crohn’s disease显示文摘 | Chinyu Su Gary R. Lichtenstein Karen Krok Colleen M. Brensinger James D. Lewis | 2004 | Gastroenterology2004，，： | 1 |
| 5 | Non-contact AtomicForce Microscopy of Starch Granules Surface, Part II : Se- lected Cereal Starches 显示文摘 | Juszczak L Fortuna T Krok F | 2003 | Starch2003，55，1： | 1 |
| 6 | Ordered mesoporous carbons显示文摘 | RYOO R JOO S H KROK M | 2001 | Adv Mater2001，13，： | 1 |
| 7 | Non-contact Atomic Force Microscopy of Starch Granules Surface, Part I: Potato and Tapioca Starches显示文摘 | Leslaw Juszczak Teresa Fortuna Franciszek Krok | 2003 | Starch2003，55，： | 1 |
| 8 | Non-contact AFM Investigation of Influence of Freezing Process on the Surface Structure of Potato Starch Granule显示文摘 | Krok F Szymonska J Tomasik P | 2000 | Applied Surface Science2000，157，： | 1 |
| 9 | Non-contact Atomic Force Microscopy of StarchGranules Surface, Part II: Selected Cereal Starches显示文摘 | Leslaw Juszczak Teresa Fortuna Franciszek Krok | 2003 | Starch2003，55，： | 1 |
| 10 | Chemical intercala- tion of magnesium into solid hosts显示文摘 | Bruce P G Krok F Nowinski J | 1991 | J Mater Chem1991，1，4： | 1 |
| 11 | Modification of granular potato starch by multiple deep-freezing and thawing显示文摘 | Szymonska J Krok F Komorowska-Czepirska E | 2003 | Carbohydrate Polymers2003，，52： | 1 |
| 12 | Multivalent cation intercalation显示文摘 | Bruce P G Krok F Lightfoot P | 1992 | Solid State Ionics1992，5356，： | 1 |
| 13 | Management of autoimmune and cholestatic liver disorders显示文摘 | Krok KL Munoz SJ | 2009 | Clin Liver Dis2009，13，： | 1 |
| 14 | Structure of the cubic intercalate MgxTiS2显示文摘 | Lightfoot P Krok F Nowinski J L | 1992 | J Mater Chem1992，2，1： | 1 |
| 15 | Multivalent cation intercalation显示文摘 | Bruce P G Krok F Lightfoot P | 1992 | Solid State Ionics1992，，： | 1 |
| 16 | Atomic-scale fric- tion on stepped surfaces of ionic erystals显示文摘 | Steiner P Gnecco E Krok F Budzioch J Walczak L Konior J Szymonski M Meyer E | 2011 | Physical Review Letters2011，106，18： | 1 |
| 17 | Electrical and structural study of BICOVOX显示文摘 | Krok F Abraham I Bangobango D G | 1996 | Solid State Ionics1996，86，1： | 1 |
| 18 | Studies on preparation and electrical conductivity of BICOVOX显示文摘 | Krok F Bogusz W Jakubowski W | 1994 | Solid State Ionics1994，70，1： | 1 |
| 19 | Deep-freezing of potato starch显示文摘 | Joanna Szymonska Franciszek Krok and Piotr Tomasik | 2002 | International Journal of Biological Macromolecules2002，，7： | 1 |
| 20 | Electrical conductivity and structure correlation in BIZNVOX显示文摘 | Krok F Abrahams I Zadrozna A | 1999 | Solid State Ionics1999，119，1： | 1 |
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