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| 1 | Natural Variation in OsPRR37 Regulates Heading Date and Contributes to Rice Cultivation at a Wide Range of Latitudes显示文摘标题日期和光周期敏感是决定米饭改编到大量 geographicenvironments 的基本特点。由印射的量的特点地点(QTL ) 和候选人基因分析使用整个染色体重新定序,我们 foundthat Oryza sativa 伪反应 Regulator37 (OsPRR37;此后 PRR37 ) 为早 heading7-2 (EH7-2 ) 负责从迟了标题的米饭 Milyang23 (M23 ) 和早标题的米饭 H143 的一个十字被识别的 /Heading date2 (Hd2 ) QTL。在 CCT 的不变地保存的氨基酸的 H143 containsa 错误感觉变化(CONSTANS,共同喜欢,并且 TOC1 ) PRR37 protein.In 的领域世界米饭收集, nonfunctional PRR37 等位基因的不同类型在许多欧洲、亚洲的米饭栽培变种被发现。尤其是,在自然长天的条件下面极其早怀有 Ghd7/Hd4 和 PRR37/Hd2 花的 nonfunctional 等位基因的装饰用的梨树变化,并且被使适应米饭耕作的极北的区域,多达 53 ?? ? 攠潸祣瑳 ????? 楶牴 ??? 啅?? | Bon-Hyuk Koo Soo-Cheul Yoo Joon-Woo Park Choon-Tak Kwon Byoung-Doo Lee Gynheung An Zhanying Zhang linjie Li Zichao Li Nam-Chon Paek | 2013 | Molecular Plant2013，6，6： | 42 |
| 2 | Neuroinflammation in neurodegenerative disorders:the roles of microglia and astrocytes显示文摘Neuroinflammation is associated with neurodegenerative diseases,such as Alzheimer's disease,Parkinson's disease,ancamyotrophic lateral sclerosis.Microglia and astrocytes are key regulators of inflammatory responses in the central nervous system.The activation of microglia and astrocytes is heterogeneous and traditionally categorized as neurotoxi(M1-phenotype microglia and A1-phenotype astrocytes)or neuroprotective(M2-phenotype microglia and A2-phenotype astrocytes).However,this dichotomized classification may not reflect the various phenotypes of microgliaand astrocytes.The relationship between these activated glial cells is also very complicated,and the phenotypic distribution can change,based on the progression of neurodegenerative diseases.A better understanding of the rolesof microglia and astrocytes in neurodegenerative diseases is essential for developing effective therapies.In this review,we discuss the roles of inflammatory response in neurodegenerative diseases,focusing on the contributions of microglia and astrocytes and their relationship.In addition,we discuss biomarkers to measure neuroinflammation andstudies on therapeutic drugs that can modulate neuroinflammation. | Hyuk Sung Kwon Seong-Ho Koh | 2020 | Translational Neurodegeneration2020，9，4： | 40 |
| 3 | Changes in Small Intestinal Motility and Related Hormones by Acupuncture Stimulation at Zusanli(ST 36) in Mice显示文摘Objective: To clarify the effects of acupuncture stimulation at Zusanli(ST 36) on the hormonal changes. Methods: Eight-week-old male C57BL/6 mice received acupuncture stimulation at acupoint ST 36 or Quchi(LI 11) once a day for 3 or 5 days in the acupuncture-stimulated groups, but not received in the normal group(n=6 in each group). On day 3 or 5, animals were given 0.1 m L of charcoal orally with a bulbed steel needle, 30 min after the last acupuncture stimulation. Ten minutes later, mice were anesthetized, and the intestinal transit and the concentrations of vasoactive intestinal peptide(VIP), motilin, ghrelin and gastrin in the serum were measured. Results: Compared to no acupuncture stimulation, acupuncture stimulation at ST 36 for 5 days increased the intestinal transit and down-regulated the concentration of VIP and up-regulated the concentrations of motilin, ghrelin and gastrin(P<0.05 or 0.01), whereas acupuncture stimulation at LI 11 did not change them significantly(P>0.05). Conclusion: Acupuncture stimulation at ST 36 for 5 days enhances the small intestinal motility and regulates the secretion of hormones related to small intestinal motility. | Jung-Hee Jang Deuk-Joo Lee Chang-Hwan Bae Ki-Tae Ha Sunoh Kwon Hi-Joon Park Dae-Hyun Hahm Hyejung Lee Seungtae Kim | 2017 | Chinese Journal of Integrative Medicine2017，23，3： | 29 |
| 4 | 一体化PET/CT与3.0 T全身MRI对非小细胞肺癌分期的对照研究显示文摘目的前瞻性对照一体化PET/CT和3.0T全身MRI确定非小细胞肺癌(NSCLC)TMN分期的诊断效用。方法本研究经伦理委员会批准.所有受试者均签署知情同意书。本研究包括了病理证实的165例NSCLC病人(男125例,女40例,平均年龄61岁),均进行了PET/CT平扫和全身MRI检查。病理结果作为T(n=123)和N(n=150)的分期参考标准,病理结果或随访的影像结果作为M(n=54)的分期参考标准。采用McNemas检验对PET/CT和全身MR成像对NSCLC的分期诊断作用进行对照检验。结果123例原发肺癌中,PET/CT正确分期101例(82%), | C.A.Yi K.M. Shin K.S. Lee B.T. Kim H. Kim O.J. Kwon 高莉(译) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 25 |
| 5 | 真空热压铝和铜的固态连接(英文)显示文摘在温度623~923K下采用真空热压扩散连接铝和铜,具体工艺为在预置温度下,变形率为0.2mm/min时热压缩10min,再在炉冷过程中,以0.2mm/min成型10min。通过界面分析可以看出,合适的扩散连接温度为823K,在扩散过程中产生了3种主要的金属间化合物层,分别为Al2Cu、AlCu+Al3Cu4和Al4Cu9。3种化合物层的局部硬度分别为(4.97±0.05)、(6.33±0.00)、(6.06±0.18)GPa。 | Kwang Seok LEE Yong-Nam KWON | 2013 | Transactions of Nonferrous Metals Society of China2013，23，2： | 25 |
| 6 | Effects of Momentum Ratio and Weber Number on Spray Half Angles of Liquid Controlled Pintle Injector显示文摘一个舵栓注射者为扼杀一台液体火箭引擎并且减少引擎重量是有益的。这研究为液体气体燃料在舵栓注射者的水花特征上以各种各样的注射条件探索动量比率和威伯数字的效果。一张液体表从一张中心舵栓嘴被注射,它被一口煤气的喷气从环形的差距打破。燃料的压力落下,和舵栓洞距离被看作控制变量;使用 0.1 1.0 液体注射作为为压力的一个酒吧落下,为为舵栓洞距离的煤气的喷气和 0.2 1.0 公里的压力落下的 0.010.2 酒吧。分泌物系数在 0.75 公里的舵栓洞距离前线性地被减少然后,系数稍微被增加。水花图象被一个互补金属氧化物半导体照相机与高分辨率捕获。然后,阴影和反映的图象被分析。水花分布被 patternator 从一个舵栓尖端与 50 公里的轴的距离测量。最后,角度有指数地减少的水花一半动量比率由威伯数字划分了的关联。另外,水花一半从水花分发的角度与从捕获的图象测量的那些相比被低估。 | Min Son Kijeong Yu Jaye Koo Oh Chae Kwon Jeong Soo Kim | 2015 | Journal of Thermal Science2015，24，1： | 26 |
| 7 | Cortex cinnamomi extract prevents streptozotocin- and cytokine-induced β-cell damage by inhibiting NF-κB显示文摘AIM: To clarify the mechanism underlying the anti-diabetic activities of cortex cinnamomi extract (CCE). METHODS: To induce in vivo diabetes, mice were injected with streptozotocin (STZ) via a tail vein (100 mg STZ/kg body weight). To determine the effects of CCE, mice were administered CCE twice daily for 7 d by oral gavage starting 1 wk before the STZ injection. Blood glucose and plasma insulin concentration were measured as an index of diabetes. Also, to induce cytotoxicity of RINm5F cells, we treated with cytokines (IL-1β(2.0 ng/mL) and IFN-γ(100 U/mL)). Cell viability and nitric oxide production were measured colorimetrically. Inducible nitric oxide synthase (iNOS) mRIMA and protein expression were determined by RT-PCR and Western blotting, respectively. The activation of NF-κB was assayed by using gel mobility shift assays of nuclear extracts. RESULTS: Treatment of mice with STZ resulted in hyperglycemia and hypoinsulinemia, which was further evidenced by immunohistochemical staining of islets. However, the diabetogenic effects of STZ were completely prevented when mice were pretreated with CCE. The inhibitory effect of CCE on STZ-induced hyperglycemia was mediated through the suppression of iNOS expression. In rat insulinoma RINm5F cells, CCE completely protected against interleukin-1βand interferon-γ-mediated cytotoxicity. Moreover, RINm5F cells incubated with CCE showed significant reductions in interleukin-lp and interferon-γ-induced nitric oxide production and in iNOS mRNA and protein expression, and these findings correlated well with in vivo observations. CONCLUSION: The molecular mechanism by which CCE inhibits iNOS gene expression appears to involve the inhibition of NF-κB activation. These results reveal the possible therapeutic value of CCE for the prevention of diabetes mellitus progression. | Kang-Beom Kwon Eun-Kyung Kim Eun-Sil Jeong Young-Hoon Lee Young-Rae Lee Jin-Woo Park Do-Gon Ryu Byung-Hyun Park | 2006 | World Journal of Gastroenterology2006，12，27： | 24 |
| 8 | Biogenesis and regulation of the let-7 miRNAs and their functional implications显示文摘let-7 miRNA 是在线虫, Caenorhabditis elegans,和它的生物功能表演发现的第一 miRNAs 之一到人的从线虫的进化保存的高水平。在 C 不同。elegans,高级动物有 let-7 miRNAs 的多重 isoforms;一个一致序列把种子顺序和这些 isoforms 称为的这些 isoforms 份额被分成 let-7 miRNA 家庭。let-7 家庭的表示为发展预定和肿瘤 suppressor 功能被要求,但是必须为干细胞的自强被压制。因此, let-7 miRNA 生物的续生说必须小心地被控制。产生 let-7 miRNA,一个主要抄本被 RNA 聚合酶 II 生产然后随后由 Drosha/DGCR8, TUTase,和 Dicer 处理了。因为 let-7 处理的 dysregulation 是有害的, let-7 的生物的续生说被细胞的因素紧调整,例如 RNA 有约束力的蛋白质, LIN28A/B 和 DIS3L2。在这评论,我们讨论 let-7 miRNAs 的生物函数和生物的续生说,集中于在脊椎动物的 let-7 生物的续生说的规定的分子的机制,例如鼠标和人。 | Hosuk Lee Sungwook Han Chang Seob Kwon Daeyoup Lee | 2016 | Protein & Cell2016，7，2： | 24 |
| 9 | Acoustic radiation force impulse elastography for hepatocellular carcinoma-associated radiofrequency ablation显示文摘AIM:To evaluate the potential usefulness of acoustic radiation force impulse (ARFI) images for evaluation of hepatocellular carcinomas (HCC)-associated radiofrequency ablation. METHODS:From January 2010 to June 2010,a total of 38 patients with HCC including recurred HCCs after RFA underwent ARFI elastography. The brightness of tumor was checked and the shear wave velocity was measure-d for the-quantification of stiffne-ss. According to theb-rightne-ss,the-tumors we-re-classifie-d as b-righte-r,samecolor and darker compared with adjacent parenchyma. Using the same methods,8 patients with recurred HCCs after RFA state were evaluated about the brightness compared with adjacent RFA ablation area. RESULTS:In the 38 patients with HCCs,20 (52.6%)were brighter than surrounding cirrhotic parenchyma. Another 13 (34.2%) were darker. The others (5 cases,13.2%) were seen as the same color as the adjacent liver parenchyma. Post-RFA lesions were darker than previous tumor and surrounding parenchyma in all 38 cases. However,recurred HCCs were brighter than the treated site in all 8 cases. CONCLUSION:Using ARFI technique is helpful for differential diagnosis in order to detect recurred HCCs more easily in patients with confusing status. | Hee-Jin Kwon Myong-Jin Kang Jin-Han Cho Jong-Young Oh Kyung-Jin Nam Sang-Yeong Han Sung Wook Lee | 2011 | World Journal of Gastroenterology2011，17，14： | 21 |
| 10 | T2期胆囊癌肿瘤位置和手术范围对预后的影响:一项国际多中心研究显示文摘T2期胆囊癌根据肿瘤位置不同,进一步细分为T2a(腹膜侧)或T2b期(肝脏侧)。既往有研究认为对于腹膜侧(T2a)肿瘤,在不影响预后的情况下可避免肝脏切除,但是目前仍然缺乏可靠的证据。为了探讨肿瘤位置对T2期胆囊癌的预后价值并明确手术切除的适当范围,该研究分析了韩国、日本、智利和美国的14家医院中937例接受胆囊癌手术患者的临床及病理资料。 | Kwon W Kim H Han Y 杨发才(编译) | 2020 | 中华医学杂志2020，100，39： | 21 |
| 11 | Histopathology and TB-PCR kit analysis in differentiating the diagnosis of intestinal tuberculosis and Crohn’s disease显示文摘AIM: To compare the histopathologic features of intestinal tuberculosis (ITB) and Crohn’s disease (CD) and to identify whether polymerase chain reaction for Mycobacterium tuberculosis (TB-PCR) would be helpful for differential diagnosis between ITB and CD.METHODS: We selected 97 patients with established diagnoses (55 cases of ITB and 42 cases of CD) who underwent colonoscopic biopsies.Microscopic features of ITB and CD were reviewed,and eight pathologic parameters were evaluated.Nine cases of acid fast bacilli culture-positive specimens and 10 normal colonic tissue specimens were evaluated as the positive and negative control of the TB-PCR test,respectively.PCR assays were done using two commercial kits: kit detected IS6110 and MPB64,and kit detected IS6110 only;a manual in-house PCR method was also performed on formalin-fi xed,paraffi n-embedded colonoscopic biopsy specimens.RESULTS: Statistically significant differences were noted between ITB and CD with regard histopathologic criteria: size of granulomas (P = 0.000),giant cells (P = 0.015),caseation necrosis (P = 0.003),confluent granulomas (P = 0.001),discrete granulomas (P = 0.000),and granulomas with lymphoid cuffs (P = 0.037).However,29 cases (52.7%) of ITB showed less than fi ve kinds of pathologic parameters,resulting in confusion with CD.The sensitivities and specificities of the TB-PCR test by kit ,kit ,and the in-house PCR method were 88.9% and 100%,88.9% and 100%,and 66.7% and 100% in positive and negative controls,respectively.The PCR test done on endoscopic biopsy specimens of ITB and CD were signifi cantly different with kit (P = 0.000) and kit (P = 0.000).The sensitivities and specifi cities of TB-PCR were 45.5% and 88.1%,36.4% and 100%,and 5.8% and 100%,for kit and kit and inhouse PCR method on endoscopic biopsy specimens.Among the 29 cases of histopathologically confusing CD,10 cases assayed using kit and 6 cases assayed using kit were TB-PCR positive.A combination of histologic fi ndings and TB-PCR testing led to an increase of diagnostic sensitivity and the increase (from 47.3% to 58.2) was statistically signifi cant with kit (P = 0.000).CONCLUSION: The TB-PCR test combined with histopathologic factors appears to be a helpful technique in formulating the differential diagnosis of ITB and CD in endoscopic biopsy samples. | Joon Mee Kim Hyung Kil Kim Lucia Kim Suk Jin Choi In Suh Park Jee Young Han Young Chae Chu Kye Sook Kwon Eun Joo Kim | 2010 | World Journal of Gastroenterology2010，16，20： | 20 |
| 12 | Methylation-dependent loss of RIP3 expression in cancer represses programmed necrosis in response to chemotherapeutics显示文摘交往受体的蛋白质 kinase-3 (RIP3 或 RIPK3 ) 是执行 “ 的细胞的机械的必要部分; programmed”或 “ regulated”坏死。这里,我们证明那规划坏死响应许多化学疗法的代理人被激活并且贡献导致化疗的房间死亡。然而,我们证明那 RIP3 表情经常在化学疗法的死亡期间由于它的 transcriptional 开始地点, MLKL 的这样 RIP3 依赖的激活和下游地规划的坏死附近的 genomic methylation 是在癌症房间的 silenced 大部分被镇压。不过,有 hypomethylating 代理人的治疗恢复 RIP3 表示,并且从而以一种 RIP3 依赖的方式把敏感提升到 chemotherapeutics。RIP3 表示在 85% 乳癌病人与正常织物相比在肿瘤被减少,建议那 RIP3 缺乏断然在肿瘤生长 / 发展期间被选择。因为 hypomethylating 代理人在病人是相当容忍得好的,我们建议病人们可以从收到 hypomethylating 代理人与常规 chemotherapeutics 在治疗以前导致 RIP3 表示有益于的那 RIP3 缺乏的癌症。 | Gi-Bang Koo Michael J Morgan Da-Gyum Lee Woo-Jung Kim Jung-Ho Yoon Ja Seung Koo Seung I1 Kim Soo Jung Kim Mi Kwon Son Soon Still Hong Jean M Mulcahy Levy Daniel A Pollyea Craig T Jordan Pearlly Yan David Frankhouser Deedra Nicolet Kati Maharry Guido Marcucci Kyeong Sook Choi Hyeseong Cho ndrew Thorbum You-Sun Kim | 2015 | Cell Research2015，25，6： | 20 |
| 13 | Effect of Deformation Temperature on Microstructure and Mechanical Properties of AZ31 Mg Alloy Processed by Differential-Speed Rolling显示文摘A differential-speed rolling(DSR) was applied to AZ31 magnesium alloy sample at different rolling temperatures of 473,523,573,and 623 K with 1-pass and 2-pass operations.The microstructural evolution and mechanical properties of the deformed samples were investigated.The rolling temperature was found to be an important parameter affecting the microstructural development.After DSR at 473 K,the microstructure was more homogeneous than that obtained after deformation by equal-speed rolling(ESR).The fully recrystallized microstructures were generated after DSR at 573 and 623 K.As to mechanical properties,the yield strength(YS) and ultimate tensile strength(UTS) decreased monotonously with increasing rolling temperature.In contrast,the elongation of the DSR-deformed samples was improved as the rolling temperature increased.The strain hardening exponent(n) calculated by Hollomon equation increased with increasing the rolling temperature,which would explain an increase in the uniform elongation. | Mosab Kaseem Bong Kwon Chung Hae Woong Yang Kotiba Hamad Young Gun Ko | 2015 | Journal of Materials Science & Technology2015，31，5： | 19 |
| 14 | Design and performance simulation of a molecular Doppler wind lidar显示文摘A mobile molecular Doppler wind lidar at an eye-safe wavelength of 355 nm based on double-edge technique is being built in Hefei (China) for wind measurement from 10-to 40-km altitude. The structure of this lidar system is described. A triple Fabry-Perot etalon is employed as a frequency discriminator whose parameters are optimized. The receiver system is designed to achieve compactness and stability by putting in a standard 19-inch socket bench. Simulation results show that within the wind speed dynamic range of ±100 m/s, the horizontal wind errors due to noise are less than 1 m/s below 20-km altitude for 100-m vertical resolution, and less than 5.5 m/s from 20 km up to 40 km for 500-m vertical resolution with 400-mJ laser energy, 30-min temporal resolution, and a 45-cm aperture telescope. | 沈法华 Hyunki Cha 董吉辉 Dukhyeon Kim 孙东松 Sung Ok Kwon | 2009 | Chinese Optics Letters2009，7，7： | 17 |
| 15 | 沙地樟子松天然林南缘分布区林木竞争、空间格局及其更新特征显示文摘以呼伦贝尔沙地樟子松地理分布南缘天然林为研究对象,采用Hegyi竞争指数与点格局等分析方法,研究了沙地樟子松天然林的种群结构、种内竞争、空间格局及幼树更新等特征。结果表明:1)所调查区域天然沙地樟子松纯林处于中幼龄阶段,属增长型种群;2)其竞争指数与对象木胸径服从幂函数关系CI=242.24D^-1.12(R^2=0.91);3)幼树在小尺度上呈聚集分布,中树与大树在中大尺度上呈随机分布;幼树与中树在小尺度上呈正相关性,中树与大树在小尺度呈负相关性;4)竞争指数与更新幼树和存活更新幼树的密度均呈显著正相关性。在林分管理中需要充分考虑林木竞争、空间格局以及种群更新的关系,本研究可为沙地樟子松天然林的经营管理与保护提供重要的科学依据。 | 潘磊磊 KWON SEMYUNG 刘艳书 张晓 杨晓晖 山丹 朱媛君 时忠杰 | 2019 | 生态学报2019，39，10： | 17 |
| 16 | Fabrication of 3D Printed PCL/PEG Polyblend Scaffold Using Rapid Prototyping System for Bone Tissue Engineering Application显示文摘 | Su A Park Sang Jin Lee Ji Min Seok Jun Hee Lee Wan Doo Kim Il Keun Kwon | 2018 | Journal of Bionic Engineering2018，15，3： | 15 |
| 17 | Rice Transcription Factor OsDOFll Modulates Sugar Transport by Promoting Expression of Sucrose Transporter and SWEET Genes显示文摘 | Yunfei Wu Sang-Kyu Lee Youngchul Yoo Jinhuan Wei Suk-Yoon Kwon Sang-Won Lee Jong-Seong Jeon Gynheung An | 2018 | Molecular Plant2018，11，6： | 15 |
| 18 | Effect of vehicle weight on natural frequencies of bridges measured from traffic-induced vibration显示文摘Recently, ambient vibration test (AVT) is widely used to estimate dynamic characteristics of large civil structures. Dynamic characteristics can be affected by various environmental factors such as humidity, intensity of wind, and temperature. Besides these environmental conditions, the mass of vehicles may change the measured values when traffic-induced vibration is used as a source of AVT for bridges. The effect of vehicle mass on dynamic characteristics is investigated through traffic-induced vibration tests on three bridges; (1) three-span suspension bridge (128m+404m+128m), (2) five-span continuous steel box girder bridge (59m+3@95m+59m), (3) simply supported plate girder bridge (46m). Acceleration histories of each measurement location under normal traffic are recorded for 30 minutes at field. These recorded histories are divided into individual vibrations and are combined into two groups according to the level of vibration; one by heavy vehicles such as trucks and buses and the other by light vehicles such as passenger cars. Separate processing of the two groups of signals shows that, for the middle and long-span bridges, the difference can be hardly detected, but, for the short span bridges whose mass is relatively small, the measured natural frequencies can change up to 5.4%. | Chul-Young Kim Dae-Sung Jung Nam-Sik Kim Soon-Duck Kwon Maria Q.Feng | 2003 | Earthquake Engineering and Engineering Vibration2003，2，1： | 15 |
| 19 | 沙地天然樟子松径向生长对干旱的响应显示文摘【目的】呼伦贝尔沙地为天然樟子松分布区的南缘,气候变化呈暖干化特点,研究该区樟子松树木径向生长对气候的响应及其应对干旱的能力,有助于促进气候变化背景下沙地天然樟子松林的保护与恢复。【方法】在呼伦贝尔沙地的南辉和伊敏河两个地点建立了树轮宽度标准年表并对其变化进行比较,利用树轮宽度标准年表与气候因子进行相关分析,并计算樟子松应对极端干旱的抵抗力、恢复力和弹性力。【结果】南辉的樟子松标准年表与6月平均气温和6—7月平均最高气温呈显著负相关(P<0.05),伊敏河的樟子松年表与4月、6—7月和9月平均气温和平均最高气温呈显著负相关(P<0.05);两个地点的樟子松标准年表均与6—7月和9月的降水量正相关(P<0.1);南辉的樟子松年表与9月相对湿度呈显著负相关(P<0.05),但伊敏河的樟子松年表与前一年10—12月和当年2—3月和5月相对湿度显著正相关(P<0.05);两个地点的樟子松年表均与前一年10月至当年9月的帕尔默干旱胁迫指数(PDSI)呈显著正相关(P<0.05)。以上结果表明这一区域的樟子松径向生长受到水分的显著影响;与南辉的樟子松相比,伊敏河的樟子松对干旱的抵抗力较弱,但恢复力更强;随着干旱程度的增加,樟子松对极端干旱的抵抗力下降、恢复力增强。【结论】呼伦贝尔沙地天然樟子松径向生长受生长季气温和降水的共同影响;在1925—1935年间,两个地点的樟子松年表存在差异可能是由于伊敏河的樟子松处于幼龄,对干旱的抵抗能力较差;树龄可能会导致沙地天然樟子松应对干旱能力的差异,深入了解树龄对樟子松应对干旱能力的影响需进一步开展多点研究。 | 张晓 潘磊磊 Semyung Kwon 刘艳书 杨晓晖 时忠杰 | 2018 | 北京林业大学学报2018，40，7： | 14 |
| 20 | Long-term follow up of endoscopic resection for type 3 gastric NET显示文摘AIM:To clarify the short and long-term results and to prove the usefulness of endoscopic resection in type 3gastric neuroendocrine tumors(NETs).METHODS:Of the 119 type 3 gastric NETs diagnosed from January 1996 to September 2011,50 patients treated with endoscopic resection were enrolled in this study.For endoscopic resection,endoscopic mucosal resection(EMR)or endoscopic submucosal dissection(ESD)was used.Therapeutic efficacy,complications,and follow-up results were evaluated retrospectively.RESULTS:EMR was performed in 41 cases and ESD in 9 cases.Pathologically complete resection was performed in 40 cases(80.0%)and incomplete resection specimens were observed in 10 cases(7 vs 3 patients in the EMR vs ESD group,P=0.249).Upon analysis of the incomplete resection group,lateral or vertical margin invasion was found in six cases(14.6%)in the EMR group and in one case in the ESD group(11.1%).Lymphovascular invasions were observed in two cases(22.2%)in the ESD group and in one case(2.4%)in the EMR group(P=0.080).During the follow-up period(43.73;13-60 mo),there was no evidence of tumor recurrence in either the pathologically complete resection group or the incomplete resection group.No recurrence was reported during follow-up.In addition,no mortality was reported in either the complete resection group or the incomplete resection group for the duration of the follow-up period.CONCLUSION:Less than 2 cm sized confined submucosal layer type 3 gastric NET with no evidence of lymphovascular invasion,endoscopic treatment could be considered at initial treatment. | Yong Hwan Kwon Seong Woo Jeon Gwang Ha Kim Jin Il Kim Il-Kwun Chung Sam Ryong Jee Heung Up Kim Geom Seog Seo Gwang Ho Baik Kee Don Choi Jeong Seop Moon | 2013 | World Journal of Gastroenterology2013，19，46： | 14 |
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