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| 1 | Efficacy of Saam acupuncture treatment on improvement of immune cell numbers in cancer patients:a pilot study显示文摘OBJECTIVE: To collect preliminary data on the effects of Saam acupuncture with regard to the immunity in cancer patients.METHODS: Ten cancer patients were analyzed for improvements in immunity. Acupuncture was applied at the 5 acupuncture points, Jingqu(LU 8), Zutonggu(BL 66), Yanggu(SI 5), Yangchi(TE 4), and Zhongwan(CV 12) for 2 weeks with 4 sessions. We assessed the effect of Korean Saam acupuncture on the immune system in cancer patients by measuring particular blood cell subsets, including CD3 +,CD4+, CD8+, CD19+, and CD56+ cells, as well as total white blood cell count, absolute neutrophil count, and fatigue score. The measurement was performed before and after acupuncture and at a 2-week follow-up.RESULTS: There was a statistically significant increase in the number of CD3+(P=0.023) and CD8+ cells(P<0.001) and T-cell subsets, as well as a decrease in the fatigue severity scale(FSS) score(P=0.001) after Saam acupuncture using the 5 acupoints.CONCLUSION: Acupuncture may improve the immune system by increasing the counts of a few immune cells and relieve fatigue in cancer patients by decreasing FSS scores. Although this was a non-controlled study, it constitutes preliminary research investigating the potential effects of Saam acupuncture in increasing the counts of several immune cells in cancer patients. | Dae-Joon Kim Seong-Hoon Park Jung-Chul Seo Kyung Soon Kim Ki Cheul Sohn Im Hee Shin Hun Mo Ryoo | 2014 | Journal of Traditional Chinese Medicine2014，34，5： | 11 |
| 2 | Endoscopic retrograde cholangiopancreatography in pancreatic and biliary tract disease in Korean children显示文摘AIM:To assess the indications,findings,therapeutic procedures,safety,and complications of endoscopic retrograde cholangiopancreatography(ERCP) performed in Korean children.METHODS:The demographic characteristics,indications for ERCP,findings,therapeutic procedures,and complications of 122 pediatric patients who underwent 245 ERCPs in the Asan Medical Center between June 1994 and March 2008 were investigated.RESULTS:The mean age of the 122 patients was 8.0 ± 4.2 years.Indications were biliary pathology in 78(64.0%),pancreatic pathology in 43(35.2%),and chronic abdominal pain in one.Biliary indications included choledochal cysts in 40,choledocholithiasis in 24,suspected sclerosing cholangitis in 8,trauma in 2,and other conditions in 4.Pancreatic indications includedacute pancreatitis in 7,acute recurrent pancreatitis in 11,chronic pancreatitis in 20,trauma in 3,and pancreatic mass in 2.Of the 245 ERCPs,success rate was 98.4% and 190(77.6%) were for therapeutic purposes,including endoscopic nasal drainage(51.8%),biliary sphincterotomy(38.0%),pancreatic sphincterotomy(23.3%),stent insertion(15.1%),stone extraction(18.8%),and balloon dilatation(11.0%).Complications were postERCP pancreatitis in 16(6.5%),ileus in 23(9.4%),hemorrhage in 2(0.8%),perforation in 2(0.8%),sepsis in 1(0.4%),and impacted basket in 1(0.4%).There were no procedure-related deaths,and most complications improved under supportive care.CONCLUSION:This study showed that there is a high incidence of choledochal cyst and diagnostic and therapeutic ERCP for the management of various biliary and pancreatic diseases was safe and effective in Korean children. | Joo Young Jang Chong Hyun Yoon Kyung Mo Kim | 2010 | World Journal of Gastroenterology2010，16，4： | 7 |
| 3 | Endoscopic cyanoacrylate injection for the treatment of gastric varices in children显示文摘AIM:To evaluate the efficacy and safety of N-butyl-2-cyanoacrylate in treating acute bleeding of gastric varices in children.METHODS:The retrospective study included 21 children with 47 episodes of active gastric variceal bleeding who were treated by endoscopic injection of N-butyl-2-cyanoacrylate at Asan Medical Center Children's Hospital between August 2004 and December 2011.To reduce the risk of embolism,each injection consisted of 0.1-0.5 mL of 0.5 mL N-butyl-2-cyanoacrylate diluted with 0.5 or 0.8 mL Lipiodol.The primary outcome was incidence of hemostasis after variceal obliteration and the secondary outcome was complication of the procedure.RESULTS:The 21 patients experienced 47 episodes of active gastric variceal bleeding,including rebleeding,for which they received a total of 52 cyanoacrylate injections.Following 42 bleeding episodes,hemostasis was achieved after one injection and following five bleeding episodes it was achieved after two injections.The mean volume of each single aliquot of cyanoacrylate injected was 0.3 ± 0.1 mL(range:0.1-0.5 m L).Injection achieved hemostasis in 45 of 47(95.7%) episodes of acute gastric variceal bleeding.Eleven patients(52.4%) developed rebleeding events,with the mean duration of hemostasis being 11.1 ± 11.6 mo(range:1.0-39.2 mo).No treatment-related complications such as distal embolism were noted with the exception of abdominal pain in one patient(4.8%).Among four mortalities,one patient died of variceal rebleeding.CONCLUSION:Endoscopic variceal obliteration using a small volume of aliquots with repeated cyanoacrylate injection was an effective and safe option for the treatment of gastric varices in children. | Seak Hee Oh Seung Jin Kim Kang Won Rhee Kyung Mo Kim | 2015 | World Journal of Gastroenterology2015，21，9： | 4 |
| 4 | Prediction of the indication criteria for endoscopic resection of early gastric cancer显示文摘AIM: To find risk factors of lymph node metastasis(LNM) in early gastric cancer(EGC) and to find proper endoscopic therapy indication in EGC.METHODS: We retrospectively reviewed the 2270 patients who underwent curative operation for EGC from January 2001 to December 2008. EGC was defined as malignant lesions that do not invade beyond the submucosal layer of the stomach wall irrespective of presence of lymph node metastasis.RESULTS: Among 2270 enrolled patients, LNM was observed in 217(9%) patients. LNM in intramucosal(M) cancer and submucosal(SM) cancer was detectedin 3 8( 2. 8 %, 3 8 / 1 3 4 0) patients and 1 7 9(19%, 179/930) patients, respectively. In univariate analysis, the risk factors for LNM in EGC were size of tumor, Lauren classification, ulcer, lymphatic invasion, vascular invasion, and depth of invasion. However, in multivariate analysis, size of tumor, lymphatic invasion, vascular invasion, and depth of invasion were risk factors for LNM in EGC. Size of tumor, lymphatic invasion, vascular invasion, and depth of invasion were risk factors for LNM in cases of intramucosal cancer and submucosal cancer. In particular, there was no lymph node metastasis in cases of well differentiated early gastric cancer below 1 cm in size without ulcer regardless of lymphovascular invasion.CONCLUSION: Tumor size, perilymphatic-vascular invasion, and depth of invasion were risk factors for LNM in EGC. There was no LNM in EGC below 1 cmregardless risk factors. | Jae Hyun Park Si Hyung Lee Joon Mo Park Chan Seo Park Kyung Sik Park Eun Soo Kim Kwang Bum Cho | 2015 | World Journal of Gastroenterology2015，21，39： | 4 |
| 5 | Prediction of effluent concentration in a wastewater treatment plant using machine learning models显示文摘Of growing amount of food waste, the integrated food waste and waste water treatment was regarded as one of the efficient modeling method. However, the load of food waste to the conventional waste treatment process might lead to the high concentration of total nitrogen(T-N) impact on the effluent water quality. The objective of this study is to establish two machine learning models—artificial neural networks(ANNs) and support vector machines(SVMs), in order to predict 1-day interval T-N concentration of effluent from a wastewater treatment plant in Ulsan, Korea. Daily water quality data and meteorological data were used and the performance of both models was evaluated in terms of the coefficient of determination(R^2), Nash–Sutcliff efficiency(NSE), relative efficiency criteria(d rel). Additionally, Latin-Hypercube one-factor-at-a-time(LH-OAT) and a pattern search algorithm were applied to sensitivity analysis and model parameter optimization, respectively. Results showed that both models could be effectively applied to the 1-day interval prediction of T-N concentration of effluent. SVM model showed a higher prediction accuracy in the training stage and similar result in the validation stage.However, the sensitivity analysis demonstrated that the ANN model was a superior model for 1-day interval T-N concentration prediction in terms of the cause-and-effect relationship between T-N concentration and modeling input values to integrated food waste and waste water treatment. This study suggested the efficient and robust nonlinear time-series modeling method for an early prediction of the water quality of integrated food waste and waste water treatment process. | Hong Guo Kwanho Jeong Jiyeon Lim Jeongwon Jo Young Mo Kim Jong-pyo Park Joon Ha Kim Kyung Hwa Cho | 2015 | Journal of Environmental Sciences2015，27，6： | 4 |
| 6 | Metal stents placement for refractory pancreatic duct stricture in children显示文摘AIM To evaluate the use of fully covered self-expandable metal stents(FCSEMSs) for pancreatic duct strictures in children with chronic pancreatitis.METHODS Eight patients with refractory benign dominant stricture of the main pancreatic duct(MPD) were enrolled through chart reviews between December 2014 and June 2017 in a single center. Endoscopic retrograde cholangiopancreatography(ERCP) with placement of a 6-mm FCSEMS with dual flaps was performed. Endoscopic removal of FCSEMSs was performed with a snare or rat-tooth forceps. All procedures were performed by a pediatric gastroenterologist. For the assessment of outcomes, technical and clinical success, adverse events, and stent patency were evaluated retrospectively.RESULTS The placement and removal of the FCSEMSs were successful in all 8 patients. Five patients were boys and 3 were girls. The median age at initial FCSEMS placement was 12 years(range, 5-18 years). The diameters of all the inserted stents were 6 mm, and the lengths were 4-7 cm. The median indwelling time was 6 mo(range, 3-10 mo). No pancreatic sepsis, pancreatitis, cholestasis, or mortality occurred. There was no proximal and distal migration. All subjects showed a patent stent. On follow-up ERCP, the mean diameter of the stricture improved from 1.1 mm to 2.8 mm(P < 0.05), whereas that of upstream dilation improved from 8.4 mm to 6.3 mm(P < 0.05).CONCLUSION This initial experience showed that temporary FCSEMS placement is feasible and safe for the management of refractory benign MPD stricture in children. | In Sook Jeong Sung Hee Lee Seak Hee Oh Do Hyun Park Kyung Mo Kim | 2018 | World Journal of Gastroenterology2018，24，3： | 3 |
| 7 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int J Cancer2012，，9： | 2 |
| 8 | Clinical Characteristics and VPS33B Mutations in Patients With ARC Syndrome显示文摘 | Joo Young Jang Kyung Mo Kim Gu-Hwan Kim Eunsil Yu Jin-Joo Lee Young Seo Park Han-Wook Yoo | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009，，3： | 2 |
| 9 | Effect of niobium and titanium addition on the hot ductility of boron containing steel显示文摘 | Kyung Chul Cho Dong Jun Mun Yang Mo Koo Jae Sang Lee | 2011 | Materials Science & Engineering A2011，，： | 2 |
| 10 | Absence of p15 INK4B and p16 INK4A Gene Alterations in Primary Cervical Carcinoma Tissues and Cell Lines with Human Papillomavirus Infection显示文摘 | Jin Woo Kim Sung Eun Namkoong Soon Won Ryu Ho Shik Kim Jin Woong Shin Joon Mo Lee Dae Hoon Kim In Kyung Kim | 1998 | Gynecologic Oncology1998，，1： | 1 |
| 11 | Fabrication of carbon nanotube reinforced alumina matrix nanocomposite by sol -gel process 显示文摘 | Chan B Mo Seung I Cha Kyung T Kim | 2005 | Materals Science and Engineering A2005，395，： | 1 |
| 12 | Morbidity and mortality after non‐curative gastrectomy for gastric cancer in elderly patients显示文摘 | Jung Ho Shim Kyung Jai Ko Han Mo Yoo Seong Il Oh Dong Jin Jeon Hae Myung Jeon Cho Hyun Park Kyo Young Song | 2012 | J Surg Oncol2012，，6： | 1 |
| 13 | 碳钢管中局部流速与壁厚减薄速率之间的关系显示文摘本研究的目的是为了寻找碳钢管内湍流参数与局部壁厚减薄速率之间的关系。对几种缩小比例的管道部件进行了实验模拟和数值分析,并且对其结果进行了比较。结果显示,流体在管道中的流动行为可以通过数值分析进行模拟,并将分析结果放大至核电站的实际尺寸,对核电站进行数值分析。为了寻找湍流参数与局部磨损速率的关系,对电站给水系统中7种类型的管道(共17种管道部件)进行了数值分析。将管道的局部磨损速率(由管壁厚度实测数据得到)与湍流参数(数值分析结果)进行比较。结果表明,管道的几何因子以及流体与壁面一定角度的冲撞都会导致流体与壁面的分离,之后流体会重新回到壁面,这时流速垂直于管壁方向的分量(Vτ)的分布与局部壁厚减薄的分布非常相似。从最小二乘法拟合的结果可以推测出局部壁厚磨损速率与蚱的关系。 | Kyeong Mo HWANG Tae Eun JIN Kyung Hoon KIM 马娜(译) 王理(校) | 2010 | 国外核动力2010，31，2： | 1 |
| 14 | Unilateral Versus Bilateral Pedicle Screw Fixation in Lumbar Spinal Fusion显示文摘 | Kyung Soo Suk Hwan Mo Lee Nam Hyun Kim Jung Won Ha | 2000 | Spine2000，，14： | 1 |
| 15 | Extranodal marginal zone B-cell lymphomas of mucosa-associated lymphoid tissue–type of the orbit and ocular adnexa显示文摘 | Jae-Lyun Lee Min-Kyoung Kim Kyung Hee Lee Myung Soo Hyun Hwa Sun Chung Dong Suk Kim Sei One Shin Hee Soon Cho Sung Hwa Bae Hun Mo Ryoo | 2005 | Annals of Hematology2005，，1： | 1 |
| 16 | Quantitative Analysis for Breast Density Estimation in Low Dose Chest CT Scans 显示文摘 | Woo Kyung Moon Chung-Ming Lo Jin Mo Goo | 2014 | J Ned Syst2014，38，： | 1 |
| 17 | Sudden failure of biological nitrogen and carbon removal in the full-scale pre-denitrification process treating cokes wastewater显示文摘 | Young Mo Kim Donghee Park Dae Sung Lee Kyung A Jung Jong Moon Park | 2009 | Bioresource Technology2009，，19： | 1 |
| 18 | Sudden failure of biological nitrogen and carbon re- moval in the full-scale pre-denitrification process treating cokes wastewater显示文摘 | Young Mo Kim Donghee Park Dae Sung Lee Kyung A Jung Jong Moon Park | 2009 | Bioresource Technology2009，100，19： | 1 |
| 19 | Methylation and microsatellite status and recurrence following adjuvant FOLFOX in colorectal cancer显示文摘 | Sae‐Won Han Hyun‐Jung Lee Jeong Mo Bae Nam‐Yun Cho Kyung‐Hun Lee Tae‐Yong Kim Do‐Youn Oh Seock‐Ah Im Yung‐Jue Bang Seung‐Yong Jeong Kyu Joo Park Jae‐Gahb Park Gyeong Hoon Kang Tae‐You Kim | 2012 | Int. J. Cancer2012，，9： | 1 |
| 20 | Cholangiographic characteristics of common bile duct dilatation in children显示文摘AIM: To investigate whether children with congenital common bile duct dilatation(CBDD) differ from children with obstructive CBDD in cholangiographic characteristics.METHODS: In this retrospective cohort study, the baseline data and the results of imaging analyses were reviewed among children who had endoscopic retrograde cholangiopancreatography(ERCP) due to CBDD. ERCP was performed on all pediatric patients by experienced pediatric endoscopists. The maximal transverse diameter of the common bile duct(CBD) was measured on ERCP. To assess whether ageadjusted CBDD could be used for differential diagnosis, a CBDD severity index(SI) was calculated by dividing the measured CBD diameter by the age-corrected maximal diameter of a normal CBD. RESULTS: A retrospective medical chart review revealed that 85 consecutive children under 16 years of age with hepatobiliary disease and CBDD were referred to Seoul Asan Medical Center. Fiftyfive(64.7%) children had congenital CBDD and 30(35.3%) had obstructive CBDD. The two groups did not differ significantly in terms of clinical characteristics except for sex. The congenital and obstructive CBDD groups did not differ significantly in terms of mean CBD diameter(19.3 ± 9.6 mm vs 12.2 ± 4.1 mm, P > 0.05). However, congenital CBDD cases had a significantly higher mean SI than obstructive CBDD cases(3.62 ± 1.64 vs 1.98 ± 0.71, P = 0.01). In multivariate analysis, an SI value ≥ 2.32 and comorbidity with anomalous union of pancreaticobiliary duct(APBDU) in ERCP independently predicted congenital CBDD.CONCLUSION: Measuring the CBD may aid the differential diagnosis of both CBDD and APBDU in children. | Seak Hee Oh Soo-Hee Chang Hyun Jin Kim Jin Min Cho Ji-Hee Hwang Jung-Man Namgoong Dae Yeon Kim Young-Ah Cho Chong Hyun Yoon Kyung Mo Kim | 2015 | World Journal of Gastroenterology2015，21，20： | 1 |
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