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| 1 | 系统性药物治疗儿童银屑病的安全性显示文摘银屑病是一种常见的慢性炎症性皮肤病。成年人的发病率为2%~3%,其中大约有三分之一的患者在18岁之前发病。在儿童期,该病的发病率呈线性增长。从1970年至2000年,儿童银屑病的发病率增加了一倍多。尽管对许多轻度银屑病患儿而言,局部治疗已足够,但对更多可能影响生活质量的重度或顽固性的银屑病患儿,则往往需要系统性治疗。 | bronckers imgj seyger mmb west dp lara-corrales i tollefson m tom wl hogeling m belazarian l zachariae c mahé e siegfried e philipp s szalai z vleugels ra holland k murphy r baselga e cordoro k lambert j alexopoulos a mrowietz u kievit w paller as 邓婕(编译) 张锡宝(审校) 无 | 2017 | 皮肤性病诊疗学杂志2017，24，5： | 3 |
| 2 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 3 | Penetration resistance of lunar soils显示文摘 | Houston W N Namiq L I | 1971 | Journal of Terramechanics1971，8，1： | 2 |
| 4 | NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease显示文摘AIM:To assess whether polymorphisms in NOD2 and ATG16L1 affect cytokine responses and mycobacterium avium subspecies paratuberculosis (MAP) survival in monocytes from Crohn's disease (CD) patients.METHODS:Monocytes were isolated from peripheral blood of CD patients of known genotype for common single nucleotide polymorphisms of NOD2 and ATG16L1.Monocytes were challenged with MAP and bacterial persistence assessed at subsequent time-points.Cytokine responses were assayed using a Milliplex multi-analyte profiling assay for 13 cytokines.RESULTS:Monocytes heterozygous for a NOD2 polymorphism (R702W,P268S,or 1007fs) were more permissive for growth of MAP (P=0.045) than those without.There was no effect of NOD2 genotype on subsequent cytokine expression.The T300A polymorphism ofATG16L1 did not affect growth of MAP in our model (P=0.175),but did increase expression of cytokines interleukin (IL)-10 (P=0.047) and IL-6 (P=0.019).CONCLUSION:CD-associated polymorphisms affected the elimination of MAP fromex vivo monocytes (NOD2),or expression of certain cytokines (ATG16L1),implying independent but contributory roles in the pathogenesis of CD. | Dylan M Glubb Richard B Gearry Murray L Barclay Rebecca L Roberts John Pearson Jacqui I Keenan Judy McKenzie Robert W Bentley | 2011 | World Journal of Gastroenterology2011，17，23： | 2 |
| 5 | Sex chromosome associated satellite DNA: Evolution and conservation 显示文摘 | Singh L Purdom I F Jones K W | 1980 | Chromosome1980，79，： | 2 |
| 6 | Low-temperature sintering of alumina with liquid-forming additives显示文摘 | XUE L A CHEN I W | 1991 | J Am Ceram Soc1991，74，8： | 2 |
| 7 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 8 | Pentoxifylline treatment and penile calcifications in men Nith Peyronie's disease显示文摘 | James F Smith Alan W Shindel Yun-Ching Huang Raul I Clavijo Lawrence Flechner Benjamin N Breyer Michael L Eisenberg Tom F Lue | 2011 | Asian Journal of Andrology2011，13，2： | 2 |
| 9 | Decision support systems for major accident prevention in the chemical process industry: a developers' survey 显示文摘 | RENIERS G I L ALE B J M DULLAERT W | 2006 | Journal of Loss Prevention in the Process Industries2006，19，： | 1 |
| 10 | Vital staining of cardiac myocytes during embryonic stem cell cardiogenesis in vitro显示文摘 | LIN W I SAMUELSON L C | 1996 | Circ Res1996，78，4： | 1 |
| 11 | Fixed abrasive diamond wire machining-part Ⅰ:process monitoring and wire tension force显示文摘 | Shih A J Hardin C W Lemaster R L McSpadden S B | 2003 | International Journal Machine Tools & Manufacture2003，43，： | 1 |
| 12 | On Rational Resursive Sequences 显示文摘 | Koeie V L Ladas G Rodrigues I W | 1993 | J Math Anal Appl1993，173，： | 1 |
| 13 | Morphology and Properties of Selective Laser Sintered Bisphenol A Poly- carbonate显示文摘 | Ho H C H Cheung W L Gibson I | 2003 | Industrial and Engineering Chemistry Re- search2003，，9： | 1 |
| 14 | Sulfide inhibition of the methanogenic activity of granular sludge at various pH-levels显示文摘 | Koster I W Rinzema A de Vegt A L | 1986 | Water Research1986，20，12： | 1 |
| 15 | Effect of fatigue on force sensation显示文摘 | JONES L A HUNTER I W | 1983 | EXP Neurol1983，81，： | 1 |
| 16 | Sludge chemical composition changes under uni-directional freezing 显示文摘 | Huang W T Chang I L Lee D J | 1996 | Water Science and Technology1996，34，34： | 1 |
| 17 | Numerical analysis of thermal striping induced high cycle thermal fatigue in a mixing tee 显示文摘 | LEE J I HU L W SAHA P | 2009 | Nuclear Eng and Design2009，239，5： | 1 |
| 18 | Early urinary CCL2 is associated with the later development ofinterstitial fibrosis and tubular atrophy in renal allografts显示文摘 | Ho J Rush D N Gibson I W Karpinski M Storsley L Bestland J etal | 2010 | Trans-plantation2010，90，： | 1 |
| 19 | Chromism and luminescence in regioregular poly(3-dodecylthiophene)显示文摘 | Rumbles G Samuel I D W Magnani L | 1996 | Synthetic Metals1996，76，： | 1 |
| 20 | 5-HT2A receptor gene promoter polymorphism -1438A/G and bipolar disorder显示文摘 | Chee I S Lee S W Kim J L | 2001 | Psychiatr Genet2001，11，： | 1 |
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