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| 1 | Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density显示文摘 | W.S Simonet D.L Lacey C.R Dunstan M Kelley M.-S Chang R Lüthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.-L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell S Sander G Van | 1997 | Cell1997，，2： | 6 |
| 2 | Anal intraepithelial neoplasia: A review of diagnosis and management显示文摘Anal intraepithelial neoplasia(AIN) is a premalignant lesion of the anal mucosa that is a precursor to anal cancer. Although anal cancer is relatively uncommon, rates of this malignancy are steadily rising in the United States, and among certain high risk populations the incidence of anal cancer may exceed that of colon cancer. Risk factors for AIN and anal cancer consist of clinical factors and behaviors that are associated with the acquisition and persistence of human papilloma virus(HPV) infection. The strongest HPV-associated risk factors are HIV infection, receptive anal intercourse, and high risk sexual behavior. A history of HPVmediated genital cancer, which suggests infection with an oncogenic HPV strain, is another risk factor for AIN/anal cancer. Because progression of AIN to anal cancer is known to occur in some individuals over several years, screening for AIN and early anal cancer, as well as treatment of advanced AIN lesions, is reasonable in certain high-risk populations. Although randomized controlled trials evaluating screening and treatment outcomes are lacking, experts support routine screening for AIN in high risk populations. Screening is performed using anal cytological exams, similar to those performed in cervical cancer screening programs, along with direct tissue evaluation and biopsy via high resolution anoscopy. AIN can be treated using topical therapies such as imiquimod, 5-flurouracil, and trichloroacetic acid, as well as ablative therapies such as electrocautery and laser therapy. Reductions in AIN and anal cancer rates have been shown in studies where high-risk populations were vaccinated against the oncogenic strains of HPV. Currently, the CDC recommends both high-risk and average-risk populations be vaccinated against HPV infection using the quadrivalent or nonavalent vaccines. It is important for clinicians to be familiar with AIN and the role of HPV vaccination, particularly in high risk populations. | Joseph R Roberts Lacey L Siekas Andrew M Kaz | 2017 | World Journal of Gastrointestinal Oncology2017，9，2： | 3 |
| 3 | 年龄≥65岁男性收缩压与血管疾病的相关性显示文摘老年人血压与血管疾病的关系尚不确定。1996-1999年,在澳大利亚西部帕斯普通人群中建立65~94岁男性7564人的前瞻性队列,评估收缩压与主要血管事件的相关性。测定基线和2001-2004年再调查时的收缩压。记录受试者的致命性及非致命性血管事件。 | Lacey B Golledge J Yeap BB Lewington S McCaul KA Norman PE Flicker L Almeida OP Hankey GJ 赵狄 练桂丽 | 2017 | 中华高血压杂志2017，25，5： | 2 |
| 4 | Successes and failures in the use of parasitic nematodes for pest control 显示文摘 | Georgis R Koppenhofer AM Lacey L | 2006 | Biological Control2006，38，13： | 1 |
| 5 | Fungi as biological control agents of Bemisia tabaci显示文摘 | Lacey L A Fransen J J | | 0，，： | 1 |
| 6 | Osteoprotegerin ligand modulates murine osteoclast survival in vitro and in vivo 显示文摘 | Lacey D L Tan H L Lu J | 2000 | Am J Pathol2000，，157： | 1 |
| 7 | Osteoclast differentiation and ac- tivation显示文摘 | Boyle W J Simonet W S Lacey D L | 2003 | Nature2003，423，6937： | 1 |
| 8 | Infectivity of a bulgarian and an American strain of Steinernema carpocapsae against codling moth显示文摘 | Vega F E Lacey L A Reid A P | | 0，，： | 1 |
| 9 | Osteoprotegerin: a novel secreted protein involved in the regulation of bone density 显示文摘 | Simonet W S Lacey D L Dunstan C R | 1997 | Cell1997，89，2： | 1 |
| 10 | Insect pathogens as biological control agents: Do they have a future 显示文摘 | Lacey L A Frutos R Kaya H A | 2001 | Biological Control2001，21，： | 1 |
| 11 | Job and career satisfaction among staff Nurses显示文摘 | Shaver K H Lacey L M | 2003 | JONA2003，33，3： | 1 |
| 12 | Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation显示文摘 | LACEY D L TIMMS E TAN H L | 1998 | Cell1998，93，2： | 1 |
| 13 | Called into question: what nurses want显示文摘 | Lacey L M | 2003 | Nurs Manag2003，34，2： | 1 |
| 14 | Osteoprotegerin: a novel secreted protein involved in the regulation of bone density 显示文摘 | Simonet W S Lacey D L Dunstan C R | 1997 | Cell1997，89，2： | 1 |
| 15 | Pupal mortality and adult emer-gence of western cherry fruit fly ( Diptera: Tephritidae ) exposed tothe fungus Muscodor albus ( Xylariales:Xylariaceae) 显示文摘 | Yee W L Lacey L A Bishop B J B | 2009 | Journal ofEconomic Entomology2009，102，6： | 1 |
| 16 | Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation 显示文摘 | LACEY D L TIMMS E TAN H L | 1998 | Cell1998，93，2： | 1 |
| 17 | The potential of the fungus, Muscodor albus,as a microbial control agent of potato tuber moth ( Lepidoptera :Gelechiidae) in stored potatoes显示文摘 | Lacey L A Neven L G | 2006 | Journal of Invertebrate Patholo-gy2006，91，3： | 1 |
| 18 | Osteoprotegerin: a novel secreted protein involved in the regulation of bone density 显示文摘 | SIMONET W S LACEY D L DUNSTAN C R | 1997 | Cell1997，89，2： | 1 |
| 19 | Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by o steoprotegerin l igand显示文摘 | Hsu H Lacey DL Dunstan CR Solovyev I Colombero A Timms E Tan HL Elliott G Kelley MJ Sarosi I Wang L Xia XZ Elliott R Chiu L Black T Scully S Capparelli C Morony S Shimamoto G Bass MB Boyle WJ | | 0，，： | 1 |
| 20 | Osteoprotegerin: a novel secreted protein involved in the regulation of bone density显示文摘 | Simonet W S Lacey D L Dunstan C R | 1997 | Cell1997，89，2： | 1 |
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