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| 1 | Comparative transcriptomics of Central Asian Vitis vinifera accessions reveals distinct defense strategies against powdery mildew显示文摘Grape powdery mildew(PM),caused by the biotrophic ascomycete Erysiphe necator,is a devastating fungal disease that affects most Vitis vinifera cultivars.We have previously identified a panel of V.vinifera accessions from Central Asia with partial resistance to PM that possess a Ren1-like local haplotype.In this study,we show that in addition to the typical Ren1-associated late post-penetration resistance,these accessions display a range of different levels of disease development suggesting that alternative alleles or additional genes contribute to determining the outcome of the interaction with the pathogen.To identify potential Ren1-dependent transcriptional responses and functions associated with the different levels of resistance,we sequenced and analyzed the transcriptomes of these Central Asian accessions at two time points of PM infection.Transcriptomes were compared to identify constitutive differences and PM-inducible responses that may underlie their disease resistant phenotype.Responses to E.necator in all resistant accessions were characterized by an early up-regulation of 13 genes,most encoding putative defense functions,and a late down-regulation of 32 genes,enriched in transcriptional regulators and protein kinases.Potential Ren1-dependent responses included a hotspot of co-regulated genes on chromosome 18.We also identified 81 genes whose expression levels and dynamics correlated with the phenotypic differences between the most resistant accessions‘Karadzhandahal’,DVIT3351.27,and O34-16 and the other genotypes.This study provides a first exploration of the functions associated with varying levels of partial resistance to PM in V.vinifera accessions that can be exploited as sources of genetic resistance in grape breeding programs. | Katherine C H Amrine Barbara Blanco-Ulate Summaira Riaz Dániel Pap Laura Jones Rosa Figueroa-Balderas M Andrew Walker Dario Cantu | 2015 | Horticulture Research2015，2，1： | 3 |
| 2 | Protective effects of N-acetylcysteine on lung injury and red blood cell modification induced by carrageenan in the rat显示文摘 | Salvatore C Emanuela M laura D | 2001 | FASEB J2001，15，： | 1 |
| 3 | Effect of Glass Fiber and Maleated Ethylene-Propylene Rubber Content on the Impact Fracture Parameters of Nylon 6显示文摘 | D M Laura H Keskkula J W Barlow D R Paul | 2001 | Polymer2001，42，： | 1 |
| 4 | Semi-active control strategies for MR Dampers: Comparative study显示文摘 | Laura M J Shirley J D | 2000 | Journal of Engineering Me- chanics2000，8，： | 1 |
| 5 | Clinical and Electrophysiological Aspects of Charcot-Marie-Tooth Disease显示文摘 | Laura M Scaioli V | 2006 | Neuro Molecular Medicine2006，8，： | 1 |
| 6 | Postpartum Depreeion显示文摘 | Laura J Miller M D | 2002 | JAMA2002，287，： | 1 |
| 7 | Proyecyive effects of N-acetylcysteine on lung injury and red blood cell modification insuced by carrageenan in the rat显示文摘 | Salvatore C Emanuela M Laura D | 2001 | FASEB J2001，15，： | 1 |
| 8 | Low-grade myofibroblastic sarcoma of the oral cavity 显示文摘 | Frederica D Alessandro B Laura M | 2009 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod2009，108，2： | 1 |
| 9 | Micromechanical adhesion force measurements between tetrahydrofuran hydrate particles显示文摘 | Craig J T Laura E D Kelly T M | 2007 | Journal of Colloid and Interface Science2007，306，： | 1 |
| 10 | Production of a defensin-like antifungal protein NFAP from Neosartorya fischeri in Pichia pastoris and its antifungal activity against filamentous fungal isolates from human infections显示文摘 | Máté Virágh Dóra V?r?s Zoltán Kele Laura Kovács ádám Fizil Gergely Lakatos Gergely Maróti Gyula Batta Csaba Vágv?lgyi László Galgóczy | 2014 | Protein Expression and Purification2014，，： | 1 |
| 11 | Effect of Glass Fiber Surface Chemistry on the Mechanical Properties of Glass Fiber Reinforced, Rubber-toughened Nylon 6 显示文摘 | D M Laura H Keskkula J W Barlow D R Paul | 2002 | Polymer2002，43，： | 1 |
| 12 | Micromechanical adhesion force measurements between hydrate particles in hydrocarbon oils and their modifications显示文摘 | Laura E D Zachary M A Nathan C G | 2009 | Energy Fuels2009，23，： | 1 |
| 13 | Pat terns of local-regional recurrence following parotid sparing conforma and segmenta intensity-modulated radiotherapy for head and neck cancer显示文摘 | LAURA A D YOSHIMI A LON M | 2000 | Int J Radiat Oncol Biol Phys2000，46，5： | 1 |
| 14 | Clinical and electrophysiological aspects of Charcot-Marie-Tooth disease显示文摘 | Pareyson D Scaioli V Laura M | 2006 | Neuromolecular Med2006，8，12： | 1 |
| 15 | Micromechanical adhesion force measurements between hydrate particles in hydrocarbon oils and their modifications显示文摘 | Dieker Laura E Aman Zachary M George Nathan C Sum Amadeu K Sloan E D Koh C A | | 0，，： | 1 |
| 16 | Protective effects of N- acetycysteine on lung injury and red blood cell modification induced by carrageenan in the rat 显示文摘 | Salvatore C Emanuela M Laura D | 2001 | Paseb J2001，15，7： | 1 |
| 17 | Spatially-resolved EELS analysis of antibody distribution on biofunctionalized magnetic nanoparticles显示文摘 | Raul A Laura D M Laura C Alvaro M Marcel T Valeria G Jesus M D L F Clara M Ricardo 1 | 2013 | ACS Nano2013，7，5： | 1 |
| 18 | Biological Signatures of Asymptomatic Extra- and Intracranial Atherosclerosis: The Barcelona-AsIA (Asymptomatic Intracranial Atherosclerosis) Study显示文摘 | Elena López-Cancio Amparo Galán Laura Dorado Marta Jiménez María Hernández Mónica Millán Silvia Reverté Anna Su?ol Jaume Barallat Anna Massuet Maria Teresa Alzamora Antonio Dávalos Juan Francisco Arenillas | 2012 | Stroke2012，，10： | 1 |
| 19 | Maize HapMap2 identifies extant variation from a genome in flux 显示文摘 | Jer-Ming Chia Chi Song Peter J Bradbury Denise Cos- tich Natalia de Leon John Doebley Robert J Elshire Brandon Gaut Laura Geller Jeffrey C Glaubitz Michael Gore Kate E Guill Jim Holland Matthew B Hufford Jinsheng Lai Meng Li Xin Liu Yanli Lu Richard Mc- Combie Rebecca Nelson Jesse Poland Boddupalli M Prasanna Tanja Pyhajarvi Tingzhao Rong Rajandeep S Sekhon Qi Sun Maud I Tenaillon Feng Tian Jun Wang Xun Xu Zhiwu Zhang Shawn M Kaeppler Jef- frey Ross-lbarra Michael D McMullen Edward S Buck- ler Gengyun Zhang Yunbi Xu Doreen Ware | 2012 | Nat Genet2012，，44： | 1 |
| 20 | Effective primary isolation of wild-type Canine distemper virus in MDCK, MV1 Lu and Vero cells without nucleotide sequence changes within the entire haemagglutinin protein gene and in subgenomic sections of the fusion and phospho protein genes显示文摘 | John A Lednicky Thomas P Meehan Michael J Kinsel Jean Dubach Laura L Hungerford Nicolene A Sarich Kelley E Witecki Michael D Braid Casandra Pedrak Christiane M Houde | 2004 | Journal of Virological Methods2004，，2： | 1 |
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