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| 1 | Traveling wave effect on the seismic response of a steel arch bridge subjected to near fault ground motions显示文摘In the 1990s, several major earthquakes occurred throughout the world, with a common observation that near fault ground motion (NFGM) characteristics had a distinct impact on causing damage to civil engineering structures that could not be predicted by using far field ground motions. Since then, seismic responses of structures under NFGMs have been extensively examined, with most of the studies focusing on structures with relatively short fundamental periods, where the traveling wave effect does not need to be considered. However, for long span bridges, especially arch bridges, the traveling wave (only time delay considered) effect may be very distinct and is therefore important. In this paper, the results from a case study on the seismic response of a steel arch bridge under selected NFGMs is presented by considering the traveling wave effect with variable apparent velocities. The effects of fling step and long period pulses of NFGMs on the seismic responses of the arch bridge are also discussed. | 徐艳 George C Lee | 2007 | Earthquake Engineering and Engineering Vibration2007，6，3： | 11 |
| 2 | Near-fault ground motions with prominent acceleration pulses:pulse characteristics and ductility demand显示文摘Major earthquakes of last 15 years (e.g., Northridge 1994, Kobe 1995 and Chi-Chi 1999) have shown that many near-fault ground motions possess prominent acceleration pulses. Some of the prominent ground acceleration pulses are related to large ground velocity pulses, others are caused by mechanisms that are totally different from those causing the velocity pulses or fling steps. Various efforts to model acceleration pulses have been reported in the literature. In this paper, research results from a recent study of acceleration pulse prominent ground motions and an analysis of structural damage induced by acceleration pulses are summarized. The main results of the study include: (1) temporal characteristics of acceleration pulses; (2) ductility demand spectrum of simple acceleration pulses with respect to equivalent classes of dynamic systems and pulse characteristic parameters; and (3) estimation of fundamental period change under the excitation of strong acceleration pulses. By using the acceleration pulse induced linear acceleration spectrum and the ductility demand spectrum, a simple procedure has been developed to estimate the ductility demand and the fundamental period change of a reinforced concrete (RC) structure under the impact of a strong acceleration pulse. | Mai Tong Vladimir Rzhevskyt Dai Junwu George C Lee Qi Jincheng Qi Xiaozhai | 2007 | Earthquake Engineering and Engineering Vibration2007，6，3： | 3 |
| 3 | Tumor necrosis factor-α-induced protein 1 and immunity to hepatitis B virus显示文摘AIM: To compare the gene expression profile in a pair of HBV-infected twins.METHODS: The gene expression profile was compared in a pair of HBV-infected twins.RESULTS: The twins displayed different disease outcomes. One acquired natural immunity against HBV,whereas the other became a chronic HBV carrier. Eightyeight and forty-six genes were found to be up- or downregulated in their PBMCs, respectively. Tumor necrosis factor-alpha-induced protein 1 (TNF-αIP1) that expressed at a higher level in the HBV-immune twins was identified and four pairs of siblings with HBV immunity by RTPCR. However, upon HBV core antigen stimulation,TNF-αIP1 was downregulated in PBMCs from subjects with immunity, whereas it was slightly upregulated in HBV carriers. Bioinformatics analysis revealed a K+channel tetramerization domain in TNF-αIP1 that shares a significant homology with some human, mouse, and C elegan proteins.CONCLUSION: TNF-αIP1 may play a role in the innate immunity against HBV. | Marie C Lin Nikki P Lee Ning Zheng Pai-Hao Yang Oscar G Wong Hsiang-Fu Kung Chee-Kin Hui John M Luk George Ka-Kit Lau | 2005 | World Journal of Gastroenterology2005，11，48： | 3 |
| 4 | Acomparative study between China and U.S.on seismic design philosophy and practice of a long span arch bridge显示文摘This paper presents the first of a series of case studies on the seismic design of long span bridges (cable-stayed bridges, suspension bridges and arch bridges) under a cooperative research project on seismic behavior and design of highway bridges between the State Key Laboratory for Disaster Reduction in Civil Engineering, Tongji University and the Multidisciplinary Center for Earthquake Engineering Research, University at Buffalo. The objective of this series of case studies is to examine the differences and similarities on the seismic design practice of long span bridges in China and the U.S., to identify research needs and to develop design guidelines beneficial to bridge engineers in both countries. Unlike short to medium span bridges, long span bridges are not included in most seismic design specifications, mainly because they are location dependent and structurally unique. In this paper, an available model of a steel tied half through arch bridge with a main span of 550m in China is discussed. Analysis is focused on comparisons of the seismic responses due to different ground motions. Seismic design criteria and seismic performance requirements for long span bridges in both countries were first introduced and compared, and then three near field earthquake records with large vertical components were selected as the excitations to examine the seismic behavior and seismic vulnerability of the bridge. Results show that (1) the selected near field ground motions cause larger responses to key components (critical sections) of the bridge (such as arch rib ends) with a maximum increase of more than twice those caused by the site specific ground motions; (2) piers, longitudinal girders and arch crowns are more vulnerable to vertical motions, especially their axial forces; and (3) large vertical components of near field ground motions may not significantly affect the bridge’s internal forces provided that their peak acceleration spectra ordinates only appear at periods of less than 0.2s. However, they may have more influence on the longitudinal displacements of sliding bearings due to their large displacement spectra ordinates at the fundamental period of the bridge. | 徐艳 George C Lee 范立础 胡世德 | 2006 | Earthquake Engineering and Engineering Vibration2006，5，1： | 2 |
| 5 | Activation of the interfbron-α pathway identifies a subgroup of systemic lupus erythematosus pa- tients with distinct serologic features and active disease 显示文摘 | Kirou KA Lee C Georges S | 2005 | Ar- thritis Rheum2005，52，5： | 1 |
| 6 | On neighbor-selection strategy in hybrid peer-to-peer networks显示文摘 | Simon G M Koo Karthik Kannan C S George Lee | 2006 | Future Generation Computer Systems2006，22，： | 1 |
| 7 | Salf-Adaptive Neuro-Fuzzy Inference Systems for Classification Applications显示文摘 | Jeen-Shing Wang C S George Lee | 2002 | IEEE Trans Fuzzy Syst2002，10，6： | 1 |
| 8 | Neural-network-based fuzzy logic control and decision system显示文摘 | LIN C T LEE GEORGE C S | 1991 | IEEE Transcations on Computers1991，40，12： | 1 |
| 9 | Coordinate overexpression of interferon-α-induced genes in systemic lupus erythematosus显示文摘 | Kirou KA Lee C George S | 2004 | Arthritis Rheum2004，50，： | 1 |
| 10 | Activation of the interferon-αpathway identifies a subgroup of systemic lupus erythematosus patients with distinct serologic features and active disease显示文摘 | Kirou KA Lee C George S | 2005 | Arthritis Rheum2005，52，5： | 1 |
| 11 | Efficacy of cone-- beam computed tomography as a modality to accurately iden- tify the presence of second mesiobuccal canals in maxillary first and second molars: a pilot study 显示文摘 | Blattner T C George N Lee C C | 2010 | J Endod2010，36，5： | 1 |
| 12 | Impurity effects on high-temperature tensile ductility of iridium alloys at high strain rate显示文摘 | McKamey C G George E P Lee E H | 2000 | Scripta Mater2000，42，： | 1 |
| 13 | Isolating ligands specific for human vasculature using in vivo phage selection 显示文摘 | George A J Lee L Pitzalis C | 2003 | Trends Biotechnol2003，21，5： | 1 |
| 14 | Activation of the interferon alpha pathway identifies a subgroup of systemic lupus erythe matosus patients with distinct serologic features and active dis case显示文摘 | Kirou KA Lee C George S | 2005 | Arthritis Rheum2005，52，5： | 1 |
| 15 | Reinforcement structure/pa- rameter learning for neural-network-based fuzzy logic control systems显示文摘 | C T Lin C S George Lee | 1994 | IEEE Transactions on Fuzzy Sys- tems1994，2，1： | 1 |
| 16 | Chemotherapy and radiotherapy in nasopharyngeal carcinoma: an update of the MAC-NPC meta-analysis显示文摘 | Pierre Blanchard Anne Lee Sophie Marguet Julie Leclercq Wai Tong Ng Jun Ma Anthony T C Chan Pei-Yu Huang Ellen Benhamou Guopei Zhu Daniel T T Chua Yong Chen Hai-Qiang Mai Dora L W Kwong Shie Lee Cheah James Moon Yuk Tung Kwan-Hwa Chi George Fountzilas Li | 2015 | The Lancet Oncology2015，，： | 1 |
| 17 | Activation of the interferon-alphapathway identifies a subgroup of systemic lupus erythematosus patientswith distinct serologic features and active disease显示文摘 | Kirou KA Lee C George S | 2005 | ArthritisRheum2005，52，5： | 1 |
| 18 | Impirity effects on high-temperature tensile ductility of iridium alloys at high strain rate显示文摘 | Mckamey C G George E P Lee E H | 2000 | Scr Mater2000，42，： | 1 |
| 19 | Native or raw starch digestion: a key step in energy efficient biorefining of grain显示文摘 | George H Robertson Dominic W S Wong Charles C Lee | 2006 | Journal of Agri- cultural and Food Chemistry2006，54，2： | 1 |
| 20 | Electrochemical effects of ALD surface modification on combustion synthesized LiNi1/3Mn1/3Co1/3O2 as a layered-cathode material显示文摘 | RILEY L A ATTA S V CAVANAGH A S YAN Y GEORGE S M LIU P DILLON A C LEE S H | 2011 | Journal of Power Sources2011，196，： | 1 |
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