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3231篇 您的检索式:作者名="LEES W R"
    题名 作者 年代 出处 被引量
1Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed.Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee 2014World Journal of Clinical Oncology2014,5,2:5
2Multi-slice Technology in computered tomography显示文摘Dawson P Lees W R 2001Clini Radiol2001,56,4:2
3Long-term outcomes of autoimmune pancreatitis: a multicentre, international analysis显示文摘Phil A Hart Terumi Kamisawa William R Brugge Jae Bock Chung Emma L Culver László Czakó Luca Frulloni Vay Liang W Go Thomas M Gress Myung-Hwan Kim Shigeyuki Kawa Kyu Taek Lee Markus M Lerch Wei-Chih Liao Matthias L?hr Kazuichi Okazaki Ji Kon Ryu Nicolas Sc 2013Gut2013,,12:2
4Fault diagnosis and temperature sensor recovery for an air-handling unit显示文摘LEE W Y HOUSE J M SHIN D R 1997ASHRAE Transactions1997,,:2
5卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
6Preslaughter diet management in sheep and goats:effects on physiological responses and microbial loads on skin and carcass显示文摘Sixteen crossbred buck goats(Kiko x Spanish;BW = 32.8 kg) and wether sheep(Dorset x Suffolk;BW = 39.9 kg) were used to determine the effect of preslaughter diet and feed deprivation time(FDT) on physiological responses and microbial loads on skin and carcasses.Experimental animals were fed either a concentrate(CD) or a hay diet(HD)for 4 d and then deprived of feed for either 12-h or 24-h before slaughter.Blood samples were collected for plasma Cortisol and blood metabolite analyses.Longisimus muscle(LM) pH was measured.Skin and carcass swabs were obtained to assess microbial loads.Plasma creatine kinase activity(863.9 and 571.7 ± 95.21 IU) and non-esterified fatty acid concentrations(1,056.1 and 589.8 + 105.01 mEq/L) were different(P< 0.05) between sheep and goats.Species and diet treatments had significant effects on the ultimate pH of LM.Pre-holding total coliform(TCC) and aerobic plate counts(APC) of skin were significantly different between species.Goats had lower(P < 0.05) TCC(2.1 vs.3.0 log_(10) CFU/cm^2) and APC(8.2 vs.8.5 log_(10) CFU/cm^2) counts in the skin compared to sheep.Preslaughter skin E.coli counts and TCC were different(P < 0.05) between species.Goats had lower(P < 0.05) counts of E.coli(2.2 vs.2.9 log_(10) CFU/cm^2) and TCC(2.3 vs.3.0 log_(10) CFU/cm^2) in the skin compared with those in sheep.Diet,species,and FDT had no effect(P> 0.05) on E.coli and TCC in carcass swab samples.The APC of carcass swab samples were only affected(P < 0.05) by the FDT.The results indicated that preslaughter dietary management had no significant changes on hormone and blood metabolite concentrations and sheep might be more prone for fecal contamination than goats in the holding pens at abattoir.Govind Kannan Venkat R Gutta Jung Hoon Lee Brou Kouakou Will R Getz George W McCommon 2015Journal of Animal Science and Biotechnology2015,6,1:2
7An effective stress model for liquefaction显示文摘Finn W D L Lee K W Martin G R 1977Journal of the Geotechnical Engineering Division ASCE1977,103,6:2
8The fetal arm:Individualized growth assessment in normal pregnancies 显示文摘Lee W Deter R L McNie B 2005J Ultrasound Med2005,24,6:1
9Application of solidphase microextraction and gas chromatography-mass spectrometry for the determination of chlorophenols in urine显示文摘LEE M R YEH Y C HSIANG W S 1998Chromatogr B Biomed Sci Appl1998,,707:1
10Transformation of alfalfa with a bacterial fusion gene,Mannheimia haemolytica A1 leukotoxin50-gfp:response with Agrobacterium tumefaciens strains LBA4404 and C58显示文摘 Lee R W H Ro R Shewen P Strommer J 2004Plant Cell Tissue and Organ Culture2004,79,:1
11A comparative illustration of AI plmming-based Web services composition 显示文摘OH S C LEE D W KUMARA S R T 2006ACM SlGecom Exchanges2006,5,5:1
12Effeet of time,dose and fractiona -tion on temporal lobe necrosis following radiotherapy for na- sopharyngeal carcinoma显示文摘Lee A W Foo W Chappell R 1998Int J Radiat Oncol Biol Phys1998,40,1:1
13Novel furanylarylene arylsulfonylindolesulfonamides:synthesis and their antibacterial evaluation显示文摘Chennan R Lee I S Kwak Y W 2009Chem Pharm Bull2009,57,6:1
14Examination and characterization of distribution system biofilms显示文摘LeChevallier M W Babcock T M Lee R G 1987Applied and Environmental Microbiology1987,53,12:1
15Oxidation,sulfidation and hot corrosion of intermetallic compound Fe3Al at 605 ℃ and 800 ℃显示文摘Lee W H Lin R Y 1999Material Chemistry and Physics1999,58,:1
16Corredates of leaf optieal properties in tropical forest sun and extreme-shade plants显示文摘Lee D W Bone R E Tersis S 1990American Journal of Botany1990,77,:1
17The effect of cordierite additives on microwave magnetic properties of LiZn ferrites显示文摘yong S Cho Jung W Lee Vasantha R W Amarakoon 2005Materials Letters2005,59,:1
18Microstructural analysis of corroded alumina-spinel castable refractories 显示文摘KORGUL P WILSON D R LEE W E 1997J Eur Ceram Soc1997,17,:1
19Magnesium toxicity: effect on phosphorus utilization by broiler chicks显示文摘Lee S R Britton W B 1980Poult Sci1980,59,:1
20Universal amplification and analysis of pathogen 16S rRNA for classification and identification of mycoplasmalike organisms 显示文摘Lee I M Hammond R W Davis R E 1993Phytopathology1993,83,8:1
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