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| 1 | Genotypic Characterization of Methicillin-resistant Staphylococcus aureus Isolated from Pigs and Retail Foods in China显示文摘Objective To investigate the genotypic diversity of Methicillin-resistant Staphylococcus aureus(MRSA) isolated from pigs and retail foods from different geographical areas in China and further to study the routes and rates of transmission of this pathogen from animals to food. Methods Seventy-one MRSA isolates were obtained from pigs and retail foods and then characterized by multi-locus sequencing typing(MLST), spa typing, multiple-locus variable number of tandem repeat analysis(MLVA), pulsed-field gel electrophoresis(PFGE), and antimicrobial susceptibility testing. Results All isolated MRSA exhibited multi-drug resistance(MDR). Greater diversity was found in food-associated MRSA(7 STs, 8 spa types, and 10 MLVA patterns) compared to pig-associated MRSA(3 STs, 1 spa type, and 6 MLVA patterns). PFGE patterns were more diverse for pig-associated MRSA than those of food-associated isolates(40 vs. 11 pulse types). Among the pig-associated isolates, CC9-ST9-t899-MC2236 was the most prevalent clone(96.4%), and CC9-ST9-t437-MC621(20.0%) was the predominant clone among the food-associated isolates. The CC9-ST9 isolates showed significantly higher antimicrobial resistance than other clones. Interestingly, CC398-ST398-t034 clone was identified from both pig-and food-associated isolates. Of note, some community-and hospital-associated MRSA strains(t030, t172, t1244, and t4549) were also identified as food-associated isolates. Conclusion CC9-ST9-t899-MC2236-MDR was the most predominant clone in pigs, but significant genetic diversity was observed in food-associated MRSA. Our results demonstrate the great need for improved surveillance of MRSA in livestock and food and effective prevention strategies to limit MDR-MRSA infections in China. | WANG Wei LIU Feng ZULQARNAIN Baloch ZHANG Cun Shan MA Ke PENG Zi Xin YAN Shao Fei HU Yu Jie GAN Xin DONG Yin Ping BAI Yao LI Feng Qin YAN Xiao Mei MA Ai Guo XU Jin | 2017 | Biomedical and Environmental Sciences2017，30，8： | 13 |
| 2 | Orexin A attenuates the sleep-promoting effect of adenosine in the lateral hypothalamus of rats显示文摘Orexin neurons within the lateral hypothalamus play a crucial role in the promotion and maintenance of arousal. Studies have strongly suggested that orexin neurons are an important target in endogenous adenosine-regulated sleep homeostasis. Orexin A induces a robust increase in the firing activity of orexin neurons, while adenosine has an inhibitory effect. Whether the excitatory action of orexins in the lateral hypothalamus actually promotes wakefulness and reverses the sleep-producing effect of adenosine in vivo is less clear. In this study,electroencephalographic and electromyographic recordings were used to investigate the effects of orexin A and adenosine on sleep and wakefulness in rats. We found that microinjection of orexin A into the lateral hypothalamus increased wakefulness with a concomitant reduction of sleep during the first 3 h of post-injection recording, and this was completely blocked by a selective antagonist for orexin receptor 1,SB 334867. The enhancement of wakefulness also occurred after application of the excitatory neurotransmitter glutamate in the first 3 h post-injection. However, in the presence of the NMDA receptor antagonist APV, orexin A did not induce any change of sleep and wakefulness in the first 3 h.Further, exogenous application of adenosine into the lateral hypothalamus induced a marked increase of sleep in the first 3-h post-injection. No significant change in sleep and wakefulness was detected after adenosine application followed by orexin A administration into the same brain area. These findings suggest that the sleep-promoting action of adenosine can be reversed by orexin A applied to the 丨ate「a丨 hypothalamus, perhaps by exciting giutamatergic input to orexin neurons via the action0 f orexin receptor | Yanping Cun Lin Tang Jie Yan Chao He Yang Li Zhian Hu Jianxia Xia | 2014 | Neuroscience Bulletin2014，30，5： | 8 |
| 3 | Heat shock induction of a 65 kDa ATP-binding proteinase in rat C6 glioma cells显示文摘The 45, 55, 65 and 100 kDa ATP-binding proteinases (ATP-BPases) of the heat-shocked (44 ℃ for 30 min, recovery for 12h) rat C6 glioma cells were purified by DEAE-ionexchange and ATP-affinity chromatography. Their molecular masses, isoelectric points (pI), pH-optima and other properties were analyzed by native proteinase gels.It was shown that the 65 kDa ATP-BPase is specifically induced by heat shock and not detectable in control cells.Its N-terminal 1-9 amino acid sequence was determined by Edman degradation, but no homologies to other proteins in the protein data bases were found. 30 and 31 kDa proteinases can be cleaved from the 45, 55 and 65 kDa proteinases to which they are linked. A possible relationship of the heat-induced 65 kDa ATP-BPase with the ATP-dependent proteinases (ATP-DPases) in prokaryotes and eukaryotes is discussed. | XU CUN SHUAN WEI MING ZHANG DIETER TECHEL MARCO MEYER YAN ZHANG LI LUDGER RENSING (Department of Biology, Henan Normal University,Xinxiang 453002)(Institute of Cell Biology, Bremen University, D-28359 Bremen, Germany) | 1999 | Cell Research1999，9，2： | 8 |
| 4 | APE1 polymorphisms are associated with colorectal cancer susceptibility in Chinese Hans显示文摘AIM:To study the association between four base excision repair gene polymorphisms and colorectal cancer risk in a Chinese population.METHODS:Two hundred forty-seven colorectal cancer(CRC)patients and three hundred cancer-free controls were enrolled in this study.Four polymorphisms(OGG1Ser326Cys,APE1 Asp148Glu,-141T/G in the promoter region,and XRCC1 Arg399Gln)in components of the base excision repair pathway were determined in patient blood samples using polymerase chain reaction with confronting two-pair primers.The baseline information included age,gender,family history of cancer,and three behavioral factors[smoking status,alcohol consumption,and body mass index(BMI)].χ2tests were used to assess the Hardy-Weinberg equilibrium,the distributions of baseline characteristics,and the four gene polymorphisms between the cases and controls.Multivariate logistic regression analyses were conducted to analyze the correlations between the four polymorphisms and CRC risk,adjusted by the baseline characteristics.Likelihood ratio tests were performed to analyze the gene-behavior interactions of smoking status,alcohol consumption,and BMI on polymorphisms and CRC susceptibility.RESULTS:The APE1 148 Glu/Glu genotype was significantly associated with an increased risk of colorectal cancer(OR=2.411,95%CI:1.497-3.886,P<0.001relative to Asp/Asp genotype).There were no associations between OGG1,XRCC1,or APE1 promoter polymorphisms and CRC risk.A multivariate analysis including three behavioral factors showed that the APE1 148Glu/Glu genotype was associated with an increased risk for CRC among both smokers and non-smokers,non-drinkers and individuals with a BMI≥25 kg/m2(ORs=2.356,3.299,2.654,and 2.581,respectively).The XRCC1 399 Arg/Gln genotype was associated with a decreased risk of CRC among smokers and drinkers(OR=0.289,95%CI:0.152-0.548,P<0.001,and OR=0.327,95%CI:0.158-0.673,P<0.05,respectively).The APE1 promoter polymorphism-141 T/G genotype was associated with a reduced risk of colorectal cancer among subjects with a BMI<25 kg/m2(OR=0.214,95%CI:0.069-0.660,P<0.05 relative to T/T genotype).There were significant gene-behavior interactions between smoking status and XRCC1 Arg399Gln,as well as BMI and APE1-141T/G polymorphism(all P<0.05).CONCLUSION:APE1 Asp148Glu is associated with increased CRC risk and smoking alters the association between XRCC1 Arg399Gln and CRC risk in the Chinese Han population. | Shi-Heng Zhang Lin-Ang Wang Zheng Li Yu Peng Yan Ping Cun Nan Dai Yi Cheng He Xiao Yan-Li Xiong Dong Wang | 2014 | World Journal of Gastroenterology2014，20，26： | 8 |
| 5 | Association of WNK1 exon 1 polymorphisms with essential hypertension in Hani and Yi minorities of China显示文摘在有在少数的必要高血压的 1 WNK1 基因中国的 Hani 和 Yi 组织的 exon 的多型性的协会在盒子控制学习被调查。包含 WNK1 基因 exon 的 1257 bp 的顺序 1 在 1307 个个人(649 个必要高血压题目和 658 控制) 被决定在 Hani 和 Yi 少数组识别 SNP。十一以前已知的 SNP (rs3168640, rs11885, rs11554421 和 rs34880640 ) 中的四个被识别。SNP 分析显示 SNP rs11885 和 rs11554421 显著地在 Hani 和 Yi 人口与高血压被联系,并且 rs34880640 显著地在 Hani 然而并非在 Yi 人口与高血压被联系,为 covariates 调整了。Haplotype 分析显示 haplotype H1 显著地减少了在两张人口的高血压的风险。这些结果建议 WNK1 多型性在 Hani 和 Yi 人口涉及必要高血压的倾向,它的效果显示出清楚的人口特性。这发现在决定基因因素把疾病治疗与疾病并且这样联系了支持了人口特性的重要性。 | Yina Cun Jin Li Wenru Tang Xiaozhi Sheng Haijing Yu Bingrong Zheng Chunjie Xiao | 2011 | Journal of Genetics and Genomics2011，38，4： | 7 |
| 6 | Analysis of factors affecting the prognosis of transcatheter arterial chemoembolization for hepatitis B-related hepatocellular carcinoma显示文摘Objectives:The purpose of this study was to investigate the prognostic factors for transcatheter arterial chemoembolization(TACE)for hepatitis B-related hepatocellular carcinoma(HCC).Materials and methods:The variables that may affect overall survival(OS),such as age,gender,AFP,Child Pugh classification,body mass index,HBV-DNA,Hbe Ag,tumor number,tumor diameter,BCLC stage,embolization method,ablation therapy,and targeted therapy,were analyzed by single factor and many factor COX regression.In addition,predictive factors of OS were stratified and a Kaplan-Meier survival curve was drawn.Results:Among the 136 patients,the median follow-up time was 14.5 months(range:2–72 months).HCC patients with the tumor diameter<3 cm had the highest survival rate,followed by patients with a tumor diameter of 3–5 cm;the survival rate of patients with the tumor diameter(greater than 5 cm)was the lowest.Among the BCLC stages,stage A patients had the highest survival rate,followed by stage B and stage C patients,which had the lowest survival rate.The survival rate of Child Pugh grade A patients was higher than those with Child Pugh grade B.Compared with patients who did not undergo ablation treatment,the survival rate of patients with combined ablation treatment was relatively high.The survival rate of patients receiving drug-eluting beads transarterial chemoembolization(DEB-TACE)treatment was higher than those receiving conventional transarterial chemoembolization(c TACE)treatment.Additionally,repeated TACE treatment improved the OS rate of patients.These six factors were related to patient prognosis and the differences were statistically significant(P<0.05).Conclusions:Tumor diameter,BCLC stage,TACE repetition,and TACE combined with ablation were independent prognostic factors of OS. | Jiangping Cun Yonghui Xu Weidong Li Xingxiang Zhao | 2021 | Journal of Interventional Medicine2021，4，2： | 7 |
| 7 | PEG-400 as an efficient reaction medium for the synthesis of 2,4,5-triaryl-1H-imidazoles and 1,2,4,5-tetraaryl-1H-imidazoles显示文摘为一个壶的一个有效协议多,把 PEG-400 用作反应媒介的各种各样的 2,4,5-triaryl-1H-imidazoles 和 1,2,4,5-tetraaryl-1H-imidazoles 的部件合成被描述。这个方法有好收益,更少的污染和简单反应条件的优点。 | Xi Cun Wang Hai Peng Gong Zheng Jun Quan Lei Li He Lin Ye | 2009 | Chinese Chemical Letters2009，20，1： | 6 |
| 8 | Diallyl trisulfide induces apoptosis and inhibits proliferation of A549 cells in vitro and in vivo显示文摘肺癌症是在整个世界的癌症相关的死亡的领先的原因。在最近的年里,肺的腺癌在频率超过了有鳞的房间癌并且是在许多国家的肺癌症的占优势的形式。流行病学的调查显示出在消费和死亡从许多癌症评估的大蒜(瞀或蒜之类 sativum ) 之间的一种反的关系。Diallyl trisulfide (DATS ) 是导出大蒜的混合物之一(是也知道:organosulfer 混合物,振荡) 。DATS 能导致 apoptosis 并且禁止许多癌症细胞线的生长。我们的学习证明 DATS 导致的 apoptotic 事件是通过导致了 Bax/Bcl-2 和 caspase-3, -8, 和 -9 的活动的比率的起来规定的 anti-apoptotic Bcl-2 的重要减少的线粒体依赖者 caspase 串联。最后, DATS 导致了 apoptosis 并且在一个集中依赖者和时间依赖者举止禁止了增长。由与 A549 异种皮移植建立女 BALB/c 裸体老鼠的一个动物模特儿,没有与控制组相比引起重量损失或任何另外的副作用,而且,我们在裸体老鼠发现 DATS 的那口头的 gavage A549 异种皮移植的显著地延迟的生长。在 vitro 并且在 vivo 的所有证据建议 DATS 能是理想的反癌症药。 | Wenjun Li Hui Tian Lin Li Shuhai Li Weiming Yue Zhitao Chen Lei Qi Wensi Hu Yingchao Zhu Bin Hao Cun Gao Libo Si Fei Gao | 2012 | Acta Biochimica et Biophysica Sinica2012，44，7： | 6 |
| 9 | Alterations of brain local functional connectivity in amnestic mild cognitive impairment显示文摘Background:Resting-state functional magnetic resonance imaging studies using a regional homogeneity(ReHo)method have reported that amnestic mild cognitive impairment(aMCI)was associated with abnormalities in local functional connectivity.However,their results were not conclusive.Methods:Seed-based d Mapping was used to conduct a coordinate-based meta-analysis to identify consistent ReHo alterations in aMCI.Results:We identified 10 studies with 11 datasets suitable for inclusion,including 378 patients with aMCI and 435 healthy controls.This meta-analysis identified significant ReHo alterations in patients with aMCI relative to healthy controls,mainly within the default mode network(DMN)(bilateral posterior cingulate cortex[PCC],right angular gyrus,bilateral middle temporal gyri,and left parahippocampal gyrus/hippocampus),executive control network(right superior parietal lobule and dorsolateral prefrontal cortex),visual network(right lingual gyrus and left middle occipital gyrus),and sensorimotor network(right paracentral lobule/supplementary motor area,right postcentral gyrus and left posterior insula).Significant heterogeneity of ReHo alterations in the bilateral PCC,left parahippocampal gyrus/hippocampus,and right superior parietal lobule/angular gyrus was observed.Exploratory meta-regression analyses indicated that general cognitive function,gender distribution,age,and education level partially contributed to this heterogeneity.Conclusions:This study provides provisional evidence that aMCI is associated with abnormal ReHo within the DMN,executive control network,visual network,and sensorimotor network.These local functional connectivity alterations suggest coexistence of functional deficits and compensation in these networks.These findings contribute to the modeling of brain functional connectomes and to a better understanding of the neural substrates of aMCI.Confounding factors merit much attention and warrant future investigations. | Dan Zheng Wei Xia Zhong Quan Yi Pan Wen Zhao Jian Guo Zhong Hai Cun Shi Hua Liang Li Zhen Yu Dai Ping Lei Pan | 2018 | Translational Neurodegeneration2018，7，1： | 5 |
| 10 | Impact of Temperature on Mortality in Three Major Chinese Cities显示文摘Objective To study the relation between temperature and mortality by estimating the temperature-related mortality in Beijing,Shanghai,and Guangzhou.Methods Data of daily mortality,weather and air pollution in the three cities were collected.A distributed lag nonlinear model was established and used in analyzing the effects of temperature on mortality.Current and future net temperature-related mortality was estimated.Results The association between temperature and mortality was J-shaped,with an increased death risk of both hot and cold temperature in these cities.The effects of cold temperature on health lasted longer than those of hot temperature.The projected temperature-related mortality increased with the decreased cold-related mortality.The mortality was higher in Guangzhou than in Beijing and Shanghai.Conclusion The impact of temperature on health varies in the 3 cities of China,which may have implications for climate policy making in China. | ZHANG Jing LI Tian Tian TAN Jian Guo HUANG Cun Rui KAN Hai Dong | 2014 | Biomedical and Environmental Sciences2014，27，7： | 5 |
| 11 | Functional analysis of transcriptional regulation of herpes simplex virus type 1 tegument protein VP22显示文摘The herpes simplex virus type 1 (HSV-1) tegument proteins have important functions in the viral repli- cation process. In order to investigate the role of the HSV-1 tegument protein VP22 in viral replication, its transcriptional regulation of viral promoters was investigated using the chloramphenicol acetyl- transferase (CAT) assay. The results indicate that VP22 exerts a dose-dependent transcriptional in- hibitory effect on the HSV-1 α4, TK, and gC gene promoters. VP22 had the capacity to repress tran- scriptional activation of promoters via different viral transcription regulatory factors such as VP16 and ICP0, as evidenced by the specific repression of the TK and gC gene promoters by ICP0. In addition, VP22 was capable of inhibiting the promotion of ICP0 transcriptional activation in the presence of HAT PCAF, which is even more remarkable than the VP22 repression of ICP0 transcriptional activation. Fi- nally, the transcriptional inhibitory effect of VP22 on other viral promoters was demonstrated by the analysis of β-galactosidase activities in internal controls. | YU Xian1,2, LI WeiZhong1, LIU LongDing1, CHE YanChun1, CUN Wei1, WU WenJuan1, HE ChunYan1, SHAO CongWen1 & LI QiHan1 1 Department of Viral Immunology, Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China 2 Institute of Materia Medica, North Sichuan Medical College, Nanchong 637007, China | 2008 | Science China(Life Sciences)2008，51，11： | 4 |
| 12 | Probing PM_(2.5) with terahertz wave显示文摘The goal of continuous ambient participate monitoring has been accomplished by the use of terahertz(THz)wave.The frequency-dependent spectrum and absorbance of the particulate matter(PM2.5)were measured in the range of 0–10 THz.The PM2.5 concentration was calculated according to the sampling time and air flow.With the increase of,the THz wave amplitude gradually decreased and the absorbance A of PM2.5 increased.The relationship between and A can be described mathematically through A0.5.Our results demonstrate that the terahertz wave could be a valuable tool to monitor and inspect the PM2.5 concentration. | LI Qian ZHAO Kun ZHANG Lei Wei LIANG Chuan ZHANG Zhen Wei ZHANG Cun Lin HAN Dong Hai | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，12： | 4 |
| 13 | Transcriptional regulation of the Herpes Simplex Virus 1α-gene by the viral immediate-early protein ICP22 in association with VP16显示文摘Herpes Simplex Virus 1 (HSV1) is capable of inducing two forms of infection in individuals, and the establishment of which type of infection occurs is linked to the transcriptional activation of viral α genes. One of the HSV1 α genes, ICP22, is known to have multiple functions during virus replication, but its distinct roles are still unclear. This study showed that ICP22 functions as a general repressor for certain viral and cellular promoters, and this transcriptional repression by ICP22 is independent of the specific upstream promoter element, as shown using the CAT enzyme assay system. Further work also found that VP16 interfered with ICP22 mediated transcriptional repression of the viral α4 gene, through interactions with specific elements upstream of the α4 gene promoter. These findings support the possibility that ICP22 and VP16 control transcription of HSV1α genes in a common pathway for the establishment of either viral lytic or latent infections. | CUN Wei, GUO Lei, ZHANG Ying, LIU LongDing, WANG LiChun, LI JianFeng, DONG ChengHong, WANG JinJin & LI QiHan Institute of Medical Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Kunming 650118, China | 2009 | Science China(Life Sciences)2009，52，4： | 4 |
| 14 | Pirfenidone suppresses the abnormal activation of human Müller cells after platelet-derived growth factor-BB stimulation显示文摘AIM: To determine the effect of pirfenidone on the activated human Müller cells by platelet-derived growth factor-BB(PDGF-BB). METHODS: The primary human Müller cells were separated from retinal tissues and established the pathogenic model by stimulated with PDGF-BB. The Müller cells behaviour of normal group and the model group was measured by MTT assay, Trypan blue assay, cell migration assay, and collagen contraction assay. The expression of transforming growth factor(TGF)-β1,-β2, and pigment epithelium-derived factor(PEDF) was estimated with realtime polymerase chain reaction(PCR), Western blot and immunofluorescence analyses. RESULTS: A pathogenic/proliferative model of Müller cells was established by stimulating normal cultured Müller cells with 10 ng/mL PDGF-BB for 48 h. After treated with 0.2 and 0.3 mg/mL pirfenidone, the proliferation, migration and collagen contraction was statistically significantly depressed in the model group compared with the normal groups. The expression levels of TGF-β1 and TGF-β2 were significantly down-regulated, while the PEDF expression was significantly up-regulated after treated with 0.2 and 0.3 mg/mL pirfenidone in the model group. CONCLUSION: Pirfenidone effectively suppress the proliferation, migration and collagen contraction of the human Müller cells stimulated with PDGF-BB through down-regulation of TGF-β1/TGF-β2 and up-regulation of PEDF. | Yi-Jin Tao Qin Chen Li Wang Xiao Yang Qing Cun Wen-Yan Yang Hua Zhong | 2019 | International Journal of Ophthalmology(English edition)2019，12，7： | 4 |
| 15 | Mouse embryonic stem cells have increased capacity for replication fork restart driven by the specific Filia-Floped protein complex显示文摘Pluripotent 干细胞(PSC ) 在他们的快速的增长和作为结果的染色体不稳定性期间怀有组成的 DNA 复制应力在再生药妨碍他们的应用。理解复制的规章的机制在 PSC 强调反应因此是重要的。这里,我们报导胚胎的干细胞(转换字符) 是的那只老鼠比在解决复制应力的区分的房间优异。明确地,转换字符利用唯一的跳动 Filia 的蛋白质高效地支持阻止的复制的重启的复杂依赖者的机制分叉,因此维持 genomic 稳定性。转换字符特定的跳动 Filia 的建筑群在正常条件下面住在复制叉上。复制应力刺激他们的招募到阻止 Filia 的 151 残余是的叉和丝氨酸以一种 ATR 依赖的方式的 phosphorylated。这修正使跳动 Filia 的建筑群能充当功能的脚手架,它然后通过双机制支持拖延的叉重启:复制叉重启蛋白质, Blm,和刺激 ATR kinase 激活的两提高的招募。在 Blm 小径,脚手架招募 E3 ubiquitin ligase, Trim25,到阻止的复制叉,并且接着, Trim25 通过 ubiquitination 在阻止的复制叉拴住并且专注 Blm。在区分的房间,到复制叉和 ATR 发信号的激活的 Trim25-Blm 建筑群的招募由于转换字符特定的跳动 Filia 的支架的缺乏是更不柔韧的。因此,我们的学习表明转换字符利用另外、唯一的规章的层高效地支持阻止的叉重启并且维持 genomic 稳定性。 | Bo Zhao Weidao Zhang Yixian Cun Jingzheng Li Yan Liu Jing Gao Hongwen Zhu Hu Zhou Rugang Zhang Ping Zheng | 2018 | Cell Research2018，28，1： | 4 |
| 16 | Abscisic acid signaling negatively regulates nitrate uptake via phosphorylation of NRT1.1 by SnRK2s in Arabidopsis显示文摘Nitrogen(N)is a limiting nutrient for plant growth and productivity.The phytohormone abscisic acid(ABA)has been suggested to play a vital role in nitrate uptake in fluctuating N environments.However,the molecular mechanisms underlying the involvement of ABA in N deficiency responses are largely unknown.In this study,we demonstrated that ABA signaling components,particularly the three subclass Ⅲ SUCROSE NON-FERMENTING1(SNF1)-RELATED PROTEIN KINASE 2 S(SnRK2)proteins,function in root foraging and uptake of nitrate under N deficiency in Arabidopsis thaliana.The snrk2.2 snrk2.3 snrk2.6 triple mutant grew a longer primary root and had a higher rate of nitrate influx and accumulation compared with wild-type plants under nitrate deficiency.Strikingly,SnRK2.2/2.3/2.6 proteins interacted with and phosphorylated the nitrate transceptor NITRATE TRANSPORTER1.1(NRT1.1)in vitro and in vivo.The phosphorylation of NRT1.1 by SnRK2 s resulted in a significant decrease of nitrate uptake and impairment of root growth.Moreover,we identified NRT1.1Ser585 as a previously unknown functional site:the phosphomimetic NRT1.1S585 D was impaired in both low-and high-affinity transport activities.Taken together,our findings provide new insight into how plants fine-tune growth via ABA signaling under N deficiency. | Hang Su Tian Wang Chuanfeng Ju Jinping Deng Tianqi Zhang Mengjiao Li Hui Tian Cun Wang | 2021 | Journal of Integrative Plant Biology2021，63，3： | 4 |
| 17 | PEG-OSO_3H as an efficient and recyclable catalyst for the synthesis of β-amino carbonyl compounds via the Mannich reaction in PEG-H_2O显示文摘Sulfuric acid-modified polyethylene glycol 6000(PEG-OSO_3H) was applied as an efficient and recyclable catalyst for the synthesis ofβ-amino carbonyl compounds via the Mannich reaction between aldehydes,aromatic ketones and aromatic amines at room temperature using PEG400-H_2O(1:1) as environment-friendly solvents.The reactions were completed in short times and mild reaction conditions with good to excellent yields. | Xi Cun Wang Li Jia Zhang Zhang Zhang Zheng Jun Quan | 2012 | Chinese Chemical Letters2012，23，4： | 4 |
| 18 | Triboelectric nanogenerator enhanced multilayered antibacterial nanofiber air filters for efficient removal of ultrafine particulate matter显示文摘我们开发了 multilayered 抗菌剂 polyimide (PI ) nanofiber 空气为把极其细小的微粒物质(下午) 从周围的空气移开过滤的提高的高效率的旋转摩擦电 nanogenerator (R-TENG ) 。比作单人赛分层的 PI nanofiber 过滤器, multilayered nanofiber 过滤器能完全与比 0.54 m 大的直径粒子移开所有,表演为更小的下午粒子提高移动效率。在与 aR-TENG 连接以后,为极其细小的粒子的 filer 的移动效率进一步被提高。为极其细小的微粒物质的最高的移动效率在 53.3 nm 的直径是 94.1% ,平均移动效率到达 89.9% 。尽管有层数字的增加,这部电影的每单个层的厚度减少了,并且因此,过滤器的全部的压力落下减少了而不是增加。而且,因为银 nanoparticles 的小数量的增加, nanofiber 电影展出了高抗菌剂活动。有零个臭氧版本和低压力落下的这种技术为清洗空气,薄雾处理,和细菌的控制是适当的。 | Guang Qin Gu Chang Bao Han Jing Jing Tian Tao Jiang Chuan He Cun Xin Lu Yu Bai Jin Hui Nie Zhou Li Zhong Lin Wang | 2018 | Nano Research2018，11，8： | 4 |
| 19 | A new phenanthraquinone from the roots of Peucedanum praeruptorum显示文摘新混合物, 9,10-dihydrophenanthrinic 酸, 9,10-dione-3,4-methylenedioxy-8-methoxy (1 ) 从 Peucedanum praeruptorum Dunn 的根被孤立根据光谱证据。 | Cun Zhang Li Li Yong Qing Xiao Wen Li Xiao Jie Yin Guo Fang Tian Dong Dong Chen Yun Wang | 2010 | Chinese Chemical Letters2010，21，7： | 4 |
| 20 | Two new glycosides from the seeds of Cassia obtusifolia显示文摘二新 glycosides, nor-rubrofusarin-6-O-β -d-(6′-O-acetyl)glucopyranoside (1 ) 和 1-desmethylaurantio-obtusin-2-O-β -d-glucopyranoside (2 ) 从肉桂 obtusifolia 的种子被孤立,他们的结构被化学、光谱的证据建立。 | Cun Zhang Gui Liu Li Yong Qing Xiao Li Li Zhen Pang | 2009 | Chinese Chemical Letters2009，20，9： | 4 |
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