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| 1 | Adjuvant chemotherapy with paclitaxel and cisplatin in lymph node-positive thoracic esophageal squamous cell carcinoma显示文摘Objective:No standard postoperative adjuvant chemotherapy has ever been established in node-positive esophageal squamous cell carcinoma(ESCC).This is a study to explore the effect of postoperative paclitaxel(PTX)and cisplatin(DDP)in lymph node-positive,completely resected thoracic ESCC patients.Methods:We conducted a prospective phase II trial.Patients had pathologically node-positive thoracic ESCC with negative margins.Outcomes of disease-free survival(DFS)and overall survival(OS)were compared with a matched historical control cohort.The postoperative chemotherapy regimen consisted of 4 to 6 cycles of PTX 150mg/m2 administered intravenously on d 1 followed by DDP 50 mg/m2 on d 2 every 14 d.Results:Forty-three patients were accrued from December 2007 to May 2012 at Cancer Hospital of Chinese Academy of Medical Sciences for adjuvant chemotherapy.The historical control group consisted of 80 patients who received complete resection but no adjuvant chemotherapy during the same period of time.Of the 43 patients with adjuvant chemotherapy,37(86.0%)patients completed 4 to 6 cycles of chemotherapy.The 3-year DFS rates were56.3%in the adjuvant group and 34.6%in the control group(P=0.006).The 3-year OS rates were 55.0%in the adjuvant group and 37.5%in the control group(P=0.013).Multivariate analysis revealed that postoperative chemotherapy was the significant predictor for improved OS(P=0.005).Conclusions:Biweekly adjuvant PTX and DDP might improve 3-year DFS and OS in lymph node-positive,curatively resected thoracic ESCC patients.These conclusions warrant further study in randomized phase III clinical trials. | Liangze Zhang Weiwei Li Xiao Lyu Yan Song Yousheng Mao Shaoming Wang Jing Huang | 2017 | Chinese Journal of Cancer Research2017，29，2： | 15 |
| 2 | Comparative study of minimally invasive versus open esophagectomy for esophageal cancer in a single cancer center显示文摘 | Mu Juwei Yuan Zuyang Zhang Baihua Li Ning Lyu Fang Mao Yousheng Xue Qi Gao Shugeng Zhao Jun Wang Dali Li Zhishan Gao Yushun Zhang Liangze Huang Jinfeng Shao Kang Feng Feiyue Zhao Liang Li Jian Cheng Guiyu Sun Kelin He Jie | 2014 | Chinese Medical Journal2014，，4： | 13 |
| 3 | Application of video-assisted thoracic surgery in the standard operation for thoracic tumors显示文摘Objective: To evaluate the short-term outcomes of video-assisted thoracic surgery (VATS) for thoracic tumors. Methods: The data of 1,790 consecutive patients were retrospectively reviewed. These patients underwent VATS pulmonary resections, VATS esophagectomies, and VATS resections of mediastinal tumors or biopsies at the Cancer Institute & Hospital, Chinese Academy of Medical Sciences between January 2009 and January 2012. Results: There were 33 patients converted to open thoracotomy (OT, 1.84%). The overall morbidity and mortality rate was 2.79% (50/1790) and 0.28% (5/1790), respectively. The overall hospitalization and chest tube duration were shorter in the VATS lobectomy group (n=949) than in the open thoracotomy (OT) lobectomy group (n=753). There were no significant differences in morbidity rate, mortality rate and operation time between the two groups. In the esophageal cancer patients, no significant difference was found in the number of nodal dissection, chest tube duration, morbidity rate, mortality rate, and hospital length of stay between the VATS esophagectomy group (n=81) and open esophagectomy group (n=81). However, the operation time was longer in the VATS esophagectomy group. In the thymoma patients, there was no significant difference in the chest tube duration, morbidity rate, mortality rate, and hospital length of stay between the VATS thymectomy group (n=41) and open thymectomy group (n=41). However, the operation time was longer in the VATS group. The median tumor size in the VATS thymectomy group was comparable with that in the OT group. Conclusions: In early-stage (I/II) non-small cell lung cancer patients who underwent lobectomies, VATS is comparable with the OT approach with similar short-term outcomes. In patients with resectable esophageal cancer, VATS esophagectomy is comparable with OT esophagectomy with similar morbidity and mortality. VATS thymectomy for Masaoka stage I and II thymoma is feasible and safe, and tumor size is not contraindicated. Longer follow-ups are needed to determine the oncologic equivalency of VATS lobectomy, esophagectomy, and thymectomy for thymoma vs. OT. | Ju-Wei Mu Gui-Yu Chen Ke-Lin Sun Da-Wei Wang Bai-Hua Zhang Ning Li Fang Lv You-Sheng Mao Qi Xue Shu-Geng Gao Jun Zhao Da-Li Wang Zhi-Shan Li Wen-Dong Lei Yu-Shun Gao Liangze Zhang Jin-Feng Huang Kang Shao Kai Su Kun Yang Liang Zhao Fei-Yue Feng Yong-Gang Wang Jian Li Jie He | 2013 | Cancer Biology & Medicine2013，10，1： | 8 |
| 4 | Parameter estimation offinite mixtures using the EM algorithm and information criteria with application to medical image processing显示文摘 | LiangZ JaszczakRJ ColemanRE | 1992 | IEEE Trans Nucl Sci1992，39，4： | 1 |
| 5 | 显示文摘 | 张丽嫒(ZhangLY) 王晖(WangH) 梁振(LiangZ) 单亦初(ShanYC) 张丽华(ZhangLH) 张玉奎(ZhangYK) | | 分析化学0，，： | 1 |
| 6 | The evolution of China's IPR system and its impact on the patenting behaviors and strategies of multinationals in China显示文摘 | LIANGZ L XUE | 2010 | International Journal of Tech- nology Management2010，51，24： | 1 |
| 7 | A study of amino acid eompositlon and histopathology of gear tooth in industrial fluoride pollution area 显示文摘 | WangJ D Guo Y H LiangZ X | 2003 | Fluoride2003，36，3： | 1 |
| 8 | Maize Uroporphyrinogen Ⅲ Methyltransferase:overexpression of the Functional Gene Fragments in Escherichia coli and One-step Purification显示文摘 | FAN J WANG D Q LIANGZ | 2006 | Protein Expression and Purification2006，46，1： | 1 |
| 9 | Thermal con- magnetically aligned carbon nanotube bucky- nanocomposites显示文摘 | GONNETA ductivity of papers and 2006 6 ( 1 ) P LIANGZ Y C1AOI E S | 2006 | Current Applied Physics2006，，： | 1 |
| 10 | AntloxidantactivitydetectionofAstragalusmernbranaceusandCodonopsispilosulaethanolextractsbyDPPHmethod[J]显示文摘 | DUANQM(段琦梅) LIANGZS(梁宗锁) etal | | 西北植物学报0，，： | 1 |
| 11 | Charge-inducedasymmetricaldisplacementofanalignedcarbonnanotubebuckypaperactuator显示文摘 | Chen W P LiangZ Y WangB etal | 2010 | Carbon2010，48，： | 1 |
| 12 | The re- search on the design of filter banks in generalized multi- carrier technique 显示文摘 | Gao Y J Tian H Xu H B LiangZ Zhang P | 2006 | 6th International Conference on ITS Telecommunications Proceedings :519-5222006，6，： | 1 |
| 13 | Efficient software product-line model checking using induction and a SAT solver显示文摘 | Fei HE Yuan GAO Liangze YIN | 2018 | Frontiers of Computer Science2018，12，2： | 1 |
| 14 | FingerprintanalysisofophiopogonisradixbyHPLC-UV-ELSDcoupledwithchemometricsmethods显示文摘 | NINGL YANYUNC LIANGZ etal | | 中国药学英文版0，，： | 1 |
| 15 | The Emulational Simulation Fighting between Two Troops of Artillery and the Win-Probabilities 显示文摘 | Liangze Zhou Hanjiang Shen | 2000 | Advances of System Science and Application2000，2，2： | 1 |
| 16 | Large temporal window and high-resolution single-shot cross-correlator with two separate measurement channels显示文摘In strong-field physics experiments with ultraintense lasers,a single-shot cross-correlator(SSCC)is essential for fast optimization of the pulse contrast and meaningful comparison with theory for each pulse shot.To simultaneously characterize an ultrashort pulse and its long pedestal,the SSCC device must have both a high resolution and a large temporal window.However,the resolution and window in all kinds of single-shot measurement contradict each other in principle.Here we propose and demonstrate a novel SSCC device with two separate measurement channels:channel-1 for the large-window pedestal measurement has a moderate resolution but a large window,while channel-2 for the ultrashort pulse measurement has a small window but a high resolution;this allows the accurate characterization of the pulse contrast in a single shot.A two-channel SSCC device with a 200-fs resolution and 114-ps window has been developed and tested for its application in ultraintense lasers at 800 nm. | Jingui Ma Xiaoping Ouyang Liangze Pan Peng Yuan Dongfang Zhang Jing Wang Guoqiang Xie Jianqiang Zhu Liejia Qian | 2022 | High Power Laser Science and Engineering2022，10，6： | 0 |
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