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386篇 您的检索式:作者名="LIN K E"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2Reduction of dislocations in GaN epilayers grown on Si(111)substrate using SixNy inserting layer显示文摘Lee K J Shin E H Lin K Y 2004Appl Phys Lett2004,85,9:1
3Supercritical fluid extraction of lanthanides and actinides from solid materials with a fluorinated β-diketone显示文摘LIN Y H BRAUER R D LAINTZ K E 1993Anal Chem1993,65,18:1
4The role of the surgeon in the evolution of flexible endoscopy显示文摘Morgenthal C B Richards W O Dunkin B J Forde K A Vitale G Lin E 2007Surg Endosc2007,21,6:1
5Chest pain in children referred to cardiology clinic does not increase risk of sudden cardiac death显示文摘BATES K E LIN K Y 2012J Pediatr2012,160,:1
6Surface functionalization of BaTiO3 nanoparticles and improved electrical properties of BaTiO3/polyvinylidene fluoride composite显示文摘Lin M F Thakur V K Tan E J 2011RSC Adv2011,1,4:1
7Virulence and plasmid transferability of KPC Klebsiella pneumoniae at the veterans affairs healthcare system of new Jersey显示文摘Siu L K Lin J C Gomez E 2012Microb Drug Resist2012,18,4:1
8The porous structure of bituminous coal chars and its influence on combustion and gasification tmder chemically controlled conditions显示文摘Lin G Benyon P Benfell K E 2000Fuel2000,79,6:1
9Somatic mutations and altered expression of the candidate tumor suppressors CSNK1 epsilon,DLG1, and EDD/hHYD in mamumary ductal carcinoma显示文摘Fuja T J Lin F Osann K E Bryant P J 2004Cancer Res2004,64,3:1
10Double and monofunctional CD4 + and CD8 + Tcell responses to My- cobacterium tuberculosis DosR antigens and peptides in long term latently infected individuals显示文摘Commandeur S Lin M Y van Meijgaarden K E etal 2011Eur J Immunol2011,41,10:1
11Dissociation of the effects ofamylin on osteoblas t proliferation and bone resorption 显示文摘Cornish J Callon K E Lin C Q 1998Am JPhysiol1998,274,:1
12Plasma concentrations of plant ste-rols:physiology and relationship with coronary heart disease显示文摘Chan Y M Varady K A Lin Y Trautwein E Mensink R P Plat J 2006Nutr Rev2006,64,:1
13Metal-organic framework templated synthesis of Fe2 O3/TiO2 nanocomposite for hydrogen production 显示文摘Dekrafft K E Wang C Lin W 2012Advanced Materials2012,24,15:1
14Outcomes, health policy,and managed care: relationships between patient- reported outcome measures and clinical measures in outpatients with heart failure 显示文摘FLYNN K E LIN L ELLIS S J 2009Am Heart J2009,158,4:1
15Evaluation of the PAPNET cytology screening system for quality control of cervical smears显示文摘Koss LG Lin E Schreiber K 1994Am J Clin Pathol1994,101,2:1
16NCCN Clinical Practice Guidelines in Oncology:rectal cancer 显示文摘Engstrom PF Arnoletti JP Benson AB 3rd Chen YJ Choti MA Cooper HS Covey A Dilawari RA Early DS Enzinger PC Fakih MG Fleshman J Jr Fuchs C Greta JL Kiel K Knol JA Leong LA Lin E Mulcahy MF Rao S Ryan DP Saltz L Shibata D Skibber JM Sofocleous C Thomas J Venook AP Willett C 2009J Natl Compr Canc Netw2009,7,:1
17Integrated molecular and clinical analysis of AKT activation in metastatic melanoma 显示文摘Davies M A Stemke-Hale K Lin E 2009Clin Cancer Res2009,15,24:1
18The draft genome of watermelon (Citrullus lanatus ) and reseqnencing of 20 diverse accessions显示文摘Guo S G Zhang J G Sun H H Salse J Lucas W J Zhang H Y Zheng Y Mao L Y Ren Y WangZ W Min J M Guo X S Murat F Ham B K Zhang Z L Gao S Huang M Xu Y M Zhong S L Bombarely A Mueller L Zhao H He H Q Zhang Y Zhang Z H Huang S W Tan T Pang E Lin K Hu Q Kuang H H Ni P X Wang B Liu J G Kou Q H Hou W J Zou X H Jiang J Gong G Y Klee K Schoof H Huang Y Hu X S Dong S S Liang D Q Wang J Wu K Xia Y Zhao X Zheng Z Q Xing M Liang X M Huang B Q Lv T Wang J Y Yin Y Yi H P Li R Q Wu M Z Levi A Zhang X P Giovannoni J Wang J Li YF Fei Z J Xu Y 2013Nature genetics2013,45,1:1
19Catalyst specificities in high pressure hydroprocessing of pyrolysis and gasification tars显示文摘SOLTES E J LIN K S C SHEN E Y H 1987ASC Division of Fuel Chemistry1987,32,2:1
20Glucose stimulates protein modification by O-linked GlcNAc in pancreatic β-cell:Linkage of O-linked GlcNAc to β-cell death显示文摘Lin K Paterson A J Chin E 2000Proc Nail Acad Sci USA2000,97,:1
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