|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 2 | Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders显示文摘 | E Joanna Baxter Linda M Scott Peter J Campbell Clare East Nasios Fourouclas Soheila Swanton George S Vassiliou Anthony J Bench Elaine M Boyd Natasha Curtin Mike A Scott Wendy N Erber Anthony R Green | 2005 | The Lancet . 2005 (9464)2005，，： | 2 |
| 3 | Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor显示文摘 | Anne Brunet Azad Bonni Michael J Zigmond Michael Z Lin Peter Juo Linda S Hu Michael J Anderson Karen C Arden John Blenis Michael E Greenberg | 1999 | Cell1999，，6： | 2 |
| 4 | Diagnosis and management of Duchenne muscular dystrophy, part 2: implementation of multidisciplinary care显示文摘 | Katharine Bushby Richard Finkel David J Birnkrant Laura E Case Paula R Clemens Linda Cripe Ajay Kaul Kathi Kinnett Craig McDonald Shree Pandya James Poysky Frederic Shapiro Jean Tomezsko Carolyn Constantin | 2010 | Lancet Neurology2010，，2： | 1 |
| 5 | MFG-E8 regulates microglial phagocytosis of apoptotic 显示文摘 | Abby D Linda J Van E | 2008 | Neurons J Neuroimmune Pharmacol2008，3，： | 1 |
| 6 | Mind- fulness- based stress reduction compared with cognitive behav- ioral therapy for the treatment of insomnia comorbid with canc- er: A randomized, partially blinded, noninferiority trial显示文摘 | Sheila N Garland Linda E Carlson Alisa J Stephens | 2014 | Jour- nal of Clinical Oncology2014，32，5： | 1 |
| 7 | Liquefaction of Autographa californica Nucleopolyhedrovirus-Infected Insects Is Dependent on the Integrity of Virus-Encoded Chitinase and Cathepsin Genes显示文摘 | Rachael E Hawtin Tamara Zarkowska Kevin Arnold Carole J Thomas Graham W Gooday Linda A King John A Kuzio Robert D Possee | 1997 | Virology1997，，： | 1 |
| 8 | Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction 显示文摘 | JAMES L JANUZZI JR MD SHAFIQ U REHMAN M D ASIM A MOHAMMED M D ANJU BHARDWAJ M D LINDA BARAJAS R N JUSTINE BARAJAS HAN-NA KIM M D MPH AARON L BAGGISH M D RORY B WEINER M D ANNABEL CHEN-TOURNOUX MD JANE E MARSHALL RDCS STEPHANIE A MOORE M D WILLIAM D CARLSON M D GREGORY D LEWIS M D JORDAN SHIN M D DOROTHY SULLIVAN ANP KIMBERLY PARKS D O THOMAS J WANG M D SHAWN A GREGORY M D SHANMUGAM UTHAMALINGAM M D MARC J SEMIGRAN M D | 2011 | J Am Coll Cardiol2011，58，18： | 1 |
| 9 | Experimental verification of the use of metal filled via hole fences for crosstalk control of microstrip lines in LTCC packages显示文摘 | George E Yook J G Linda P B | 2001 | IEEE Transaction on Advanced Packing2001，24，1： | 1 |
| 10 | Hormesis: U-shaped dose responses and their centrality in toxicology 显示文摘 | Calabrese E J Linda A B | 2001 | Trends in Pharmacological Sciences2001，22，6： | 1 |
| 11 | River Magic:Extraordinary Experience and the Extended Service Encounter显示文摘 | Arnould E J Linda L P | 1993 | Journal of Consumer Research1993，，： | 1 |
| 12 | Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1 beta and tumor necrosis factor-a (TNFα)-dependent, and involves a TNFct receptor-associated factor- and NFκB- inducing kinase-dependent signaling mechanism 显示文摘 | Keith T Linda J Van E | 2000 | J Biol Chem2000，275，11： | 1 |
| 13 | Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1 beta and tumor necrosis factor-a (TNFα)-dependent,and involves a TNFα receptor-associated factor-and NFκB-inducing kinase-dependent signaling mechanism显示文摘 | KEITH T LINDA J VAN E | 2000 | J Biol Chem2000，275，11： | 1 |
| 14 | Acquisition, pointing and tracking performance of the hubble space telescope fine guidance sen- sors 显示文摘 | DAVID J E LINDA A R | 1992 | SPIE1992，1697，： | 1 |
| 15 | Global prevalence of norovirus in cases of gastroenteritis: a systematic review and meta-analysis显示文摘 | Sharia M Ahmed Aron J Hall Anne E Robinson Linda Verhoef Prasanna Premkumar Umesh D Parashar Marion Koopmans Benjamin A Lopman | 2014 | The Lancet Infectious Diseases2014，，： | 1 |
| 16 | Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1 beta and tumor necrosis factor-α(TNFα)-dependent, and involves a TNFα receptor- associated factor-and NFKB-inducing kinase-dependent signaling mechanism显示文摘 | Keith T Linda J Van E | 2004 | J Biol Chem2004，275，11： | 1 |
| 17 | K-ATP opener-mediated attenuation of spontaneous bladder contractions in ligature-intact, partial bladder outlet obstructed rats显示文摘 | James J Lynch Michael E Brune Nathan L Lubbers Michael J Coghlan Bryan F Cox James S Polakowski Linda L King James P Sullivan Jorge D Brioni | 2003 | Life Sciences2003，，17： | 1 |
| 18 | Circumcostal gastropexy for preventing recurrence of gastric dilatation volvulus in the dog: a evaluation of 30 cases显示文摘 | Michael Sleib Linda J Konde Wayne E Wingfield | 1985 | JAVMA1985，187，： | 1 |
| 19 | Stress,coping and immune function in breast cancer显示文摘 | Linda J Bruce E | 2002 | Annals of Behavioral Medicine2002，24，3： | 1 |
| 20 | Transaction Cost Economics, Resource Dependence Theory, and Customer-supplier Relationships 显示文摘 | Robert C F Linda F E Kenneth J H William L J | 2006 | Industrial and Corporate Change2006，15，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员