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47篇 您的检索式:作者名="LINNEBANK M"
    题名 作者 年代 出处 被引量
1The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma(英文)显示文摘Primary central nervous system lymphomas (PCNSL) frequently reveal genomic instability. We analysed different functional genetic variants affecting the folate and homocysteine metabolism important for DNA integrity in 31 PCNSL patients and 142 controls. We found significantly less carriers of the methionine synthase c. 2756A> G (D919G) missense polymorphism among the patients (0.16 vs 0.42; odds ratio 0.26, CI(95%): 0.09-0.74; P=0.005), suggesting a protective function of the G allele. These data stimulate further epidemiological and functional studies focusing on the role of homoeysteine and folate metabolism in lymphoma tumorigenesis.Linnebank M Schmidt S Kolsch H Linnebank A Heun R Schmidt-Wolf IG Glasmacher A Fliessbach K Klockgether T Schlegel U Pels H 2004中国神经肿瘤杂志2004,2,2:3
2Polymor- phisms of homocysteine metabolism are associated with intracranial aneurysms显示文摘Semmler A Linnebank M Krex D 2008Cerebrovasc Dis2008,26,4:1
3Genomic structure and transcript variants of the human methylenetetra- hydrofolate reductase gene 显示文摘Homberger A Linnebank M Winter C 2000Eur J Hum Genet2000,8,9:1
4Marked elevation in homoeysteine and homoeysteine sulfinic acid in the eerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate显示文摘Becker A Vezmar S Linnebank M 2007Int J Clin Pharmaeol Ther2007,9,45:1
5Plasmahomo-cysteine levels increase following stress in older but notyoungermen 显示文摘Kuebler U Linnebank M Semmler A 2013Psych Oneur Oendoerinology2013,38,8:1
6Clinical, enzymatic, and molecular genetic characterization of a bio- chemical variant type of argininosuccinic aciduria: prenatal and postnatal diagnosis in five unrelated families 显示文摘Kleijer WJ Garritsen VH Linnebank M 2002J In- herit Metab Dis2002,25,5:1
7Antiepileptic drugs interact with folate and vitamin B12serum levels显示文摘Linnebank M Moskau S Semmler A Widman G 2011Ann Neu-rol2011,69,2:1
8The methionine synthase polymorphism C→ G(D919G) is relevant for disease - free longevity 显示文摘Linnebank M Fliessbach K Kolscb H 2005Int J Mol Med2005,16,4:1
9A possible ge- netic link between MTHFR genotype and smoking hehav- ior显示文摘Linnebank M Moskau S Semmler A 2012PLoS One2012,7,53:1
10A Possible Genetic Link between MTHFR Genotype and Smoking Behavior显示文摘Linnebank M Moskau S Semmler A 2012PloS one2012,7,53:1
11Binding of copper is a mecha- nism of homocysteine toxicity leading to COX deficiency and apoptosis in primary neurons, PC12 and SHSY-5Y cells 显示文摘Linnebank M Lutz H Jarre E 2006Neurobiol Dis2006,23,3:1
12Argininosuc- cinate lyase (ASL) deficiency: mutation analysis in 27 pa- tients and a completed structure of the human ASL gene 显示文摘Linnebank M Tschiedel E Hberle J 2002Hum Genet2002,111,45:1
13Polymorphisms in glutathione S-transferase omega-1 and AD,vascular dementia,and stroke显示文摘Kolsch H linnebank M Lutjohann D 2004Neurology2004,63,12:1
14The methionine synthase polymorphism C→G(D919G) is relevant for disease-free longevity显示文摘Linnebank M Fliessbach K Kolsch H 2005Int J Mol Med2005,16,4:1
15Genomic structure and transcript variants of the human methylenetetrahydrofolat e reductase gene显示文摘HOMBERGER A LINNEBANK M Winter C 2000EurJ Hum Genet2000,8,9:1
16S-adenosylmethi- onine is decreased in the cerebrospinal fluid of patients with Alzheimer' s disease 显示文摘Linnebank M Popp J Smulders Y 2010Neurndegener Bis2010,7,6:1
17Polymorphisms of homocysteine metabolism are associated with intracranial aneu- rysms显示文摘SEMMLER A LINNEBANK M KREX D 2008Cerebrovasc Dis2008,26,4:1
18Polymorphisms in glu- tathione S-transferals omega-1 and AD, vascular dementia and stroke 显示文摘K lsch H Linnebank M Lutjohann D 2004Neurology2004,63,12:1
19Homocysteine and carotid intima-media thickness in a german population:lack of clinical relevance显示文摘 Moskau S Farmand S 2006Stroke2006,37,:1
20A possible genetic link between MTHFR genotype and smoking behavior 显示文摘Linnebank M Moskau S Semmler A 2012PLoSOne2012,7,53:1
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