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| 1 | Characterization of drug responses of mini patient-derived xenografts in mice for predicting cancer patient clinical therapeutic response显示文摘Background:Patient-derived organoids and xenografts(PDXs)have emerged as powerful models in functional diag-nostics with high predictive power for anticancer drug response.However,limitations such as engraftment failure and time-consuming for establishing and expanding PDX models followed by testing drug efficacy,and inability to subject to systemic drug administration for ex vivo organoid culture hinder realistic and fast decision-making in selecting the right therapeutics in the clinic.The present study aimed to develop an advanced PDX model,namely MiniPDX,for rapidly testing drug efficacy to strengthen its value in personalized cancer treatment.Methods:We developed a rapid in vivo drug sensitivity assay,OncoVee®MiniPDX,for screening clinically relevant regimens for cancer.In this model,patient-derived tumor cells were arrayed within hollow fiber capsules,implanted subcutaneously into mice and cultured for 7 days.The cellular activity morphology and pharmacokinetics were systematically evaluated.MiniPDX performance(sensitivity,specificity,positive and negative predictive values)was examined using PDX as the reference.Drug responses were examined by tumor cell growth inhibition rate and tumor growth inhibition rate in PDX models and MiniPDX assays respectively.The results from MiniPDX were also used to evaluate its predictive power for clinical outcomes.Results:Morphological and histopathological features of tumor cells within the MiniPDX capsules matched those both in PDX models and in original tumors.Drug responses in the PDX tumor graft assays correlated well with those in the corresponding MiniPDX assays using 26 PDX models generated from patients,including 14 gastric cancer,10 lung cancer and 2 pancreatic cancer.The positive predictive value of MiniPDX was 92%,and the negative predictive value was 81%with a sensitivity of 80%and a specificity of 93%.Through expanding to clinical tumor samples,Min-iPDX assay showed potential of wide clinical application.Conclusions:Fast in vivo MiniPDX assay based on capsule implantation was developed-to assess drug responses of both PDX tumor grafts and clinical cancer specimens.The high correlation between drug responses of paired MiniPDX and PDX tumor graft assay,as well as translational data suggest that MiniPDX assay is an advanced tool for personalized cancer treatment. | Feifei Zhang Wenjie Wang Yuan Long Hui Liu Jijun Cheng Lin Guo Rongyu Li Chao Meng Shan Yu Qingchuan Zhao Shun Lu Lili Wang Haitao Wang Danyi Wen | 2018 | Cancer Communications2018，38，1： | 20 |
| 2 | Autophagy in Atherosclerosis: A Phenomenon Found in Human Carotid Atherosclerotic Plaques显示文摘 | Huihui Liu Yongjun Gag Tong Tong Jijun Shi Yanlin Zhang Yaping Yang Chunfeng Liu | 2015 | Chinese Medical Journal2015，，1： | 16 |
| 3 | Inhibitory effect of blue honeysuckle extract on high-fat-diet-induced fatty liver in mice显示文摘Blue honeysuckle is rich in polyphenols, and recently receiving attention because of its potential antioxidant and anti-inflammatory properties. Nonalcoholic fatty liver disease(NAFLD) is the leading cause of chronic liver disease that develops hepatic inflammation and metabolic syndrome. The present study aims to study the effect of blue honeysuckle extract(BHE) on fat deposition and hepatic lipid peroxidation in a high-fat-diet(HFD)-induced mouse model. Mice were fed a normal diet(ND) or a HFD containing 0.5% or 1% of BHE or not for 45 d. Liver sections were stained by hematoxylin-eosin staining.Serum lipids were measured by a clinical analyzer. Insulin was examined by ELISA, and hepatic proteins were detected by Western blotting. Dietary supplementation of BHE dose-dependently suppressed HFD-induced obesity and hepatic fat deposition. Moreover, BHE improved glucose metabolism by increasing insulin sensitivity and attenuated oxidative stress potentially by up-regulating nuclear factor(erythroid-derived 2)-like 2(Nrf2)-mediated pathway. | Ming Liu Jijun Tan Ziyu He Xi He De-Xing Hou Jianhua He Shusong Wu | 2018 | Animal Nutrition2018，，3： | 13 |
| 4 | Dietary protocatechuic acid ameliorates inflammation and up-regulates intestinal tight junction proteins by modulating gut microbiota in LPS-challenged piglets显示文摘Background: Weaning is one of the major factors that cause stress and intestinal disease in piglets. Protocatechuic acid(PCA) is an active plant phenolic acid which exists in Chinese herb, Duzhong(Eucommia ulmoides Oliver), and is also considered as the main bioactive metabolite of polyphenol against oxidative stress and inflammation. This study aimed to investigate the effect of PCA on growth performance, intestinal barrier function, and gut microbiota in a weaned piglet model challenged with lipopolysaccharide(LPS).Methods: Thirty-six piglets(Pig Improvement Company line 337 × C48, 28 d of age, 8.87 kg ± 0.11 kg BW) were randomly allocated into 3 treatments and fed with a basal diet(CTL), a diet added 50 mg/kg of aureomycin(AUR), or a diet supplemented with 4000 mg/kg of PCA, respectively. The piglets were challenged with LPS(10 μg/kg BW) on d 14 and d 21 by intraperitoneal injection during the 21-d experiment. Animals(n = 6 from each group) were sacrificed after being anesthetized by sodium pentobarbital at 2 h after the last injection of LPS. The serum was collected for antioxidant indices and inflammatory cytokines analysis, the ileum was harvested for detecting mRNA and protein levels of tight junction proteins by PCR and immunohistochemical staining, and the cecum chyme was collected for intestinal flora analysis using 16 S rRNA gene sequencing.Results: Dietary supplementation of PCA or AUR significantly increased the expression of tight junction proteins including ZO-1 and claudin-1 in intestinal mucosa, and decreased the serum levels of thiobarbituric acid reactive substances(TBARS) and IL-6, as compared with CTL group. In addition, PCA also decreased the serum levels of IL-2 and TNF-α(P < 0.05). Analysis of gut microbiota indicated that PCA increased the Firmicutes/Bacteroidetes ratio(P < 0.05). Spearman's correlation analysis at the genus level revealed that PCA reduced the relative abundance of Prevotella 9, Prevotella 2, Holdemanella, and Ruminococcus torques group(P < 0.05), and increased the relative abundance of Roseburia and Desulfovibrio(P < 0.05), whereas AUR had no significant effect on these bacteria.Conclusions: These results demonstrated that both PCA and AUR had protective effect on oxidative stress, inflammation and intestinal barrier function in piglets challenged with LPS, and PCA potentially exerted the protective function by modulating intestinal flora in a way different from AUR. | Ruizhi Hu Ziyu He Ming Liu Jijun Tan Hongfu Zhang De-Xing Hou Jianhua He Shusong Wu | 2021 | Journal of Animal Science and Biotechnology2021，12，1： | 12 |
| 5 | Piglets cloned from induced pluripotent stem cells显示文摘 | Nana Fan Jijun Chen Zhouchun Shang Hongwei Dou Guangzhen Ji Qingjian Zou Lu Wu Lixiazi He Fang Wang Kai Liu Na Liu Jianyong Han Qi Zhou Dengke Pan Dongshan Yang Bentian Zhao Zhen Ouyang Zhaoming Liu Yu Zhao Lin Lin Chongming Zhong Quanlei Wang Shouqi Wang Ying Xu Jing Luan Yu Liang Zhenzhen Yang Jing Li Chunxia Lu Gabor Vajta Ziyi Li Hongsheng Ouyang Huayan Wang Yong Wang Yang Yang Zhonghua Liu Hong Wei Zhidong Luan Miguel A Esteban Hongkui Deng Huanming Yang Duanqing Pei Ning Li Gang Pei Lin Liu Yutao Du Lei Xiao Liangxue Lai | 2013 | Cell Research2013，23，1： | 12 |
| 6 | ζ-Carotene Isomerase Suppresses Tillering in Rice through the Coordinated Biosynthesis of Strigolactone and Abscisic Acid显示文摘Rice tillering is an important agronomic trait affecting grain yield.Here,we identified a high-tillering mutant tillering20(t20),which could be restored to the wild type by treatment with the strigolactone(SL)analog rac-GR24.T20 encodes a chloroplast ζ-carotene isomerase(Z-ISO),which is involved in the biosynthesis of ca-rotenoids and their metabolites,SL and abscisic acid(ABA).The t20 mutant has reduced SL and ABA,raising the question of how SL and ABA biosynthesis is coordinated,and whether they have overlapping functions in tillering.We discovered that rac-GR24 stimulated T20 expression and enhanced all-trans-p-carotene biosynthesis.Importantly,rac-GR24 also stimulated expression of Oryza sativa 9-CIS-EPOXY-CAROTENOID DIOXYGENASE 1(OsNCED1)through induction of Oryza sativa HOMEOBOX12(0sHOX12),promoting ABA biosynthesis in shoot base.On the other hand,ABA treatment significantly repressed SL biosynthesis and the ABA biosynthetic mutants displayed elevated SL biosynthesis.ABA treatment reduced the number of basal tillers in both t20 and wild-type plants.Furthermore,while ABA-deficient mu-tants aba1 and aba2 had the same number of basal tillers as wild type,they had more unproductive upper tillers at maturity.This work demonstrates complex interactions in the biosynthesis of carotenoid,SLs and ABA,and reveals a role for ABA in the regulation of rice tillering. | Xue Liu Qingliang Hu Jijun Yan Kai Sun Yan Liang Meiru Jia Xiangbing Meng Shuang Fang Yiqin Wang Yanhui Jing Guifu Liu Dianxing Wu Chengcai Chu Steven M.Smith Jinfang Chu Yonghong Wang Jiayang Li Bing Wang | 2020 | Molecular Plant2020，13，12： | 11 |
| 7 | Reservoir Characteristics of Lacustrine Shale and Marine Shale:Examples from the Songliao Basin,Bohai Bay Basin and Qiannan Depression显示文摘Lacustrine shale from the Qingshankou Formatin of Songliao basin and the Shahejie Formation of Bohai Bay basin, and marine shale from the lower Cambrian Jiumenchong Formation of Qiannan depression were analysed by using rock pyrolysis, TOC(total organic carbon), XRD(X-ray diffraction), SEM(scanning electron microscope), FE-SEM(field emission scanning electron microscope), high pressure mercury intrusion, and low pressure N_2 and CO_2 gas adsorption experiments, in aim to reveal their reservoir features. The results show that:(1) the width of micro-pores of all the studied samples mainly ranges from 0.45 to 0.7 nm indicated by CO_2 isotherms, and the width of meso-pores is less than 10 nm, with type IV adsorption isotherms and type H2 hysteresis loop, indicative of 'ink-bottle'-shaped pores. Good correlations exist among pore volume, surface area and averaged pore diameter, and a good positive correlation exists between micro-pore volume and TOC content; however, there is no obvious correlation between meso-pore volume and TOC content;(2) interparticle pores, pores among the edge of mineral grains and organic matter pores were all identified in marine and lacustrine shale, among which the interparticle pores may be influence by dissolution effect. Not all bitumen develops organic matter pore, and only high to over mature bitumen present pores. Now the description methods of micrometer scale pores developed in shale are very lack. Microfractures developed in Jiyang depression and dissolution interparticle pores developed in Songliao Basin should be the accumulation sites for shale oil in lacustrine shale, and can be as sweet spots. | WANG Min LU Shuangfang WANG Zhiwei LIU Yang HUANG Wenbiao CHEN Fangwen XU Xingyou LI Zheng LI Jijun | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 10 |
| 8 | Terrace dating as an archive of the run-through of the Sanmen Gorges显示文摘Analysis of morphological properties in the Sanmen Gorges region of the Yellow River shows that four river terraces have been developed at the entrance to the gorges. Commonly, thick aeolian loess-paleosol sequence was deposited on the terraces, which makes it easy to date the terraces. The dating of paleomagnetic, loess-paleosol sequence matching and thermoluminescence show that terraces T2, T3 and T4 were formed 0. 129 Ma, 0. 625 Ma and 0. 865 Ma ago, respectively. The formation of these terraces in this region indicates that the Yellow River has experienced four intensive downcutting events during the last 0.9 Ma. The Yellow River cut through the Sanmen Gorges and inpoured into the East China Sea no later than 0. 865 Ma. | PAN Baotian WANG Junping GAO Hongshan CHEN Yingying LI Jijun LIU Xiaofeng | 2005 | Progress in Natural Science:Materials International2005，15，12： | 9 |
| 9 | Concentration level and geographical distribution of nitrobenzene in Chinese surface waters显示文摘Nitrobenzene was reported to occur at relatively high concentrations in some Chinese surface water and to cause an environmental pollution event in 2005.To map the distribution of nitrobenzene in the Chinese surface water throughout China,surface water samples were collected from over 600 sites in the 7 major watersheds and three drainage areas.The samples were analyzed for concentration of nitrobenzene.Overall,nitrobenzene was more frequently detected at higher concentrations in the rivers of North Chin... | Jijun, Gao Linghua, Liu Xiaoru, Liu Huaidong, Zhou Zijian, Wang Shengbiao, Huang | 2008 | Journal of Environmental Sciences2008，20，7： | 9 |
| 10 | Microbial reduction of uranium(Ⅵ)by Bacillus sp.Dwc-2:A macroscopic and spectroscopic study显示文摘The microbial reduction of U(VI) by Bacillus sp. dwc-2, isolated from soil in Southwest China,was explored using transmission electron microscopy(TEM), X-ray photoelectron spectroscopy(XPS) and X-ray absorption near edge spectroscopy(XANES). Our studies indicated that approximately 16.0% of U(VI) at an initial concentration of 100 mg/L uranium nitrate could be reduced by Bacillus sp. dwc-2 at pH 8.2 under anaerobic conditions at room temperature.Additionally, natural organic matter(NOM) played an important role in enhancing the bioreduction of U(VI) by Bacillus sp. dwc-2. XPS results demonstrated that the uranium presented mixed valence states(U(VI) and U(IV)) after bioreduction, which was subsequently confirmed by XANES. Furthermore, the TEM and high resolution transmission electron microscopy(HRTEM) analysis suggested that the reduced uranium was bioaccumulated mainly within the cell and as a crystalline structure on the cell wall.These observations implied that the reduction of uranium may have a significant effect on its fate in the soil environment in which these bacterial strains occur. | Xiaolong Li Congcong Ding Jiali Liao Liang Du Qun Sun Jijun Yang Yuanyou Yang Dong Zhang Jun Tang Ning Liu | 2017 | Journal of Environmental Sciences2017，29，3： | 8 |
| 11 | Dating and genesis of the upper Weihe River terraces in Longxi basin,China显示文摘Seven terraces along the Weihe River in Longxi basin have been investigated. These terraces all consist of archetypal duality in structure, namely the floodplain deposits and the layer of gravels overlaid by varying thickness of the loess. By resorting to various dating approaches such as palaeomagnetic, optically stimulated luminescenece (OSL), 14C and loess-paleosol sequence, we provide preliminary timing of these seven terraces along upper Weihe River. Analysis on sedimentation characteristics and dating of these terraces showed that seven terraces may be jointly generated by tectonic uplifts and climatic changes. Tectonic uplifts may accommodate initial river incision, and climatic change may be responsible for processes of subsequent channel widening and aggradation. Aggradation normally occurs during glacial periods, in contrast to down-cuttings during transitions from glacial to interglacial period. Moreover, on the basis of the timings and heights of these terraces, we infer that the long-term rate of river incision was determined to be 0.2 m/kyr during the last 870 kyr, which differs from other river incision rates. This discrepancy may reflect spatio-temporal differentiation of tectonic activities in the Qinling orogenic belt during the Pleistocene. | Pan Baotian Liu Xiaofeng Gao Hongshan Wang Yong Li Jijun | 2007 | Progress in Natural Science:Materials International2007，17，11： | 7 |
| 12 | Eye movement indices in the study of depressive disorder显示文摘 | YU LI Yangyang XU Mengqing XIA Tianhong ZHANG Junjie WANG Xu LIU Yongguang HE Jijun WANG | 2016 | 上海精神医学2016，28，6： | 6 |
| 13 | Dark matter direct search sensitivity of the PandaX-4T experiment显示文摘The Panda X-4T experiment, a 4-ton scale dark matter direct detection experiment, is being planned at the China Jinping Underground Laboratory. In this paper we present a simulation study of the expected background in this experiment. In a 2.8-ton fiducial mass and the signal region between 1-10 keV electron equivalent energy, the total electron recoil background is found to be 4.9 × 10^(-5) kg^(-1) d^(-1) keV^(-1). The nuclear recoil background in the same region is 2.8 × 10^(-7) kg^(-1) d^(-1) keV^(-1). With an exposure of 5.6 ton-years, the sensitivity of Panda X-4 T could reach a minimum spin-independent dark matter-nucleon cross section of 6 × 10^(-48) cm^2 at a dark matter mass of 40 Ge V/c^2. | HongGuang Zhang Abdusalam Abdukerim Wei Chen Xun Chen YunHua Chen XiangYi Cui BinBin Dong DeQing Fang ChangBo Fu Karl Giboni Franco Giuliani LinHui Gu XuYuan Guo ZhiFan Guo Ke Han ChangDa He ShengMing He Di Huang XingTao Huang Zhou Huang Peng Ji XiangDong Ji YongLin Ju ShaoLi Li Yao Li Heng Lin HuaXuan Liu JiangLai Liu YuGang Ma YaJun Mao KaiXiang Ni JinHua Ning XiangXiang Ren Fang Shi AnDi Tan AnQing Wang Cheng Wang HongWei Wang Meng Wang QiuHong Wang SiGuang Wang XiuLi Wang XuMing Wang Zhou Wang MengMeng Wu ShiYong Wu JingKai Xia MengJiao Xiao PengWei Xie BinBin Yan JiJun Yang Yong Yang ChunXu Yu JuMin Yuan JianFeng Yue Dan Zhang Tao Zhang Li Zhao QiBin Zheng JiFang Zhou Ning Zhou XiaoPeng Zhou | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，3： | 6 |
| 14 | Bioaccumulation characterization of uranium by a novel Streptomyces sporoverrucosus dwc-3显示文摘The biosorption mechanisms of uranium on an aerobic bacterial strain Streptomyces sporoverrucosus dwc-3,isolated from a potential disposal site for(ultra-)low uraniferous radioactive waste in Southwest China,were evaluated by using transmission electron microscopy(TEM),energy dispersive X-ray(EDX)analysis,Fourier transform infrared spectroscopy(FT-IR),X-ray photoelectron spectroscopy(XPS),proton induced X-ray emission(PIXE)and enhanced proton backscattering spectrometry(EPBS).Approximately60% of total uranium at an initial concentration of 10 mg/L uranium nitrate solution could be absorbed on 100 mg S.sporoverrucosus dwc-3 with an adsorption capacity of more than3.0 mg/g(wet weight)after 12 hr at room temperature at p H 3.0.The dynamic biosorption process of S.sporoverrucosus dwc-3 for uranyl ions was well described by a pseudo second-order model.S.sporoverrucosus dwc-3 could accumulate uranium on cell walls and within the cell,as revealed by SEM and TEM analysis as well as EDX spectra.XPS and FT-IR analysis further suggested that the absorbed uranium was bound to amino,phosphate and carboxyl groups of the cells.Additionally,PIXE and EPBS results confirmed that ion exchange also contributed to the adsorption process of uranium. | Xiaolong Li Congcong Ding Jiali Liao Liang Du Qun Sun Jijun Yang Yuanyou Yang Dong Zhang Jun Tang Ning Liu | 2016 | Journal of Environmental Sciences2016，28，3： | 5 |
| 15 | ON SOURCE ANALYSIS BY WAVE SPLITTING WITH APPLICATIONS IN INVERSE SCATTERING OF MULTIPLE OBSTACLES显示文摘我们学习为声学或电磁的散布问题切开过程的波浪。过程是切开一些的这些的想法散布了地进来自不同空间区域的地的和以便这个信息能为倒置算法或为活跃噪音控制被使用。切开算法能基于一般边界层潜力表示或格林的表示公式。我们将关于不同参考领域 G 在指定参考领域 G 和远地的模式的唯一的分解外面证明散布波浪的唯一的分解。进一步,我们与二为 scatterer 为地重建采用切开的技术或更多分开部件,由把它与为波浪恢复的点来源方法相结合。用散布波浪以及它的远地的模式的分解,切开过程的波浪在这建议纸在障碍,引起远地的模式的多重障碍能独立从被重建附近把一个有效方法给散布波浪的计算。这更加在反的散布的区域扩大分解方法的范围。最后,我们将提供数字例子表明切开的方法的可行性。 | Fahmi ben Hassen Jijun Liu Roland Potthast | 2007 | Journal of Computational Mathematics2007，25，3： | 4 |
| 16 | Numerical Solution for the Helmholtz Equation with Mixed Boundary Condition显示文摘We consider the numerical solution for the Helmholtz equation in R^2 with mixed boundary conditions.The solvability of this mixed boundary value problem is estab- lished by the boundary integral equation method.Based on the Green formula,we express the solution in terms of the boundary data.The key to the numerical real- ization of this method is the computation of weakly singular integrals.Numerical performances show the validity and feasibility of our method.The numerical schemes proposed in this paper have been applied in the realization of probe method for inverse scattering problems. | Haibing Wang Jijun Liu | 2007 | Numerical Mathematics A Journal of Chinese Universities(English Series)2007，16，3： | 4 |
| 17 | DID Code:A Bridge Connecting the Materials Genome Engineering Database w让h Inheritable Integrated Intelligent Manufacturing显示文摘A data identifier(DID)is an essential tag or label in all kinds of databases—particularly those related to integrated computational materials engineering(ICME),inheritable integrated intelligent manufacturing(I3M),and the Industrial Internet ofThings.With the guidance and quick acceleration of the developme nt of advanced materials,as envisioned by official documents worldwide,more investigations are required to construct relative numerical standards for material informatics.This work proposes a universal DID format consisting of a set of build chains,which aligns with the classical form of identifier in both international and national standards,such as ISO/IEC 29168-1:2000,GB/T 27766-2011,GA/T 543.2-2011,GM/T 0006-2012,GJB 7365-2011,SL 325-2014,SL 607-201&WS 363.2-2011,and QX/T 39-2005.Each build chain is made up of capital letters and numbers,with no symbols.Moreover,the total length of each build chain is not restricted,which follows the formation of the Universal Coded Character Set in the international standard of ISO/IEC 10646.Based on these rules,the proposed DID is flexible and convenient for extendi ng and sharing in and between various cloud-based platforms.Accordingly,classical two-dimensional(2D)codes,including the Hanxin Code,Lots Perception Matrix(LP)Code,Quick Response(Q.R)code,Grid Matrix(GM)code,and Data Matrix(DM)Code,can be constructed and precisely recognized and/or decoded by either smart phones or specific machines.By utilizing these 2D codes as the fingerprints of a set of data linked with cloud-based platforms,progress and updates in the composition-processing-structure-property-performance workflow process can be tracked spontaneously,paving a path to accelerate the discovery and manufacture of advanced materials and enhance research productivity,performance,and collaboration. | William Yi Wang Peixuan Li Deye Lin Bin Tang Jun Wang Quanmei Guan Qian Ye Haixing Dai Jun Gao Xiaoli Fan Hongchao Kou Haifeng Song Feng Zhou Jijun Ma Zi-Kui Liu Jinshan Li Weimin Liu | 2020 | Engineering2020，6，6： | 4 |
| 18 | Molecular characterization of RAPD and SCAR marker linked to the frog-eye leaf spot resistance gene in soybean显示文摘Two fragments SCS362o and SCS3580 of the co-dominant marker OPS0362o&580 that were linked to the resistance gene of soybean frog-eye leaf spot have been completely sequenced. A significant insertion of 30 bp is the main reason of the polymorphism between the two fragments. The results of Southern hybridization indicate that SCS362o derives from a single- or low-copy sequence and can be used as an RFLP probe. A co-dominant SCAR marker SCSSeao&sao has been developed based on the sequences. The segregation of SCS362o&58o is similar to that of RAPD marker OPS03620&580. Significant polymorphism has been shown between resistant and susceptible genotypes when 62 soybean genotypes were surveyed for the SCAR marker. Therefore, the marker can be used in the resistance breeding of soybean frog-eye leaf spot by marker-assisted selection. | ZOU Jijun YANG Qingkai CHEN Shouyi CHEN Qingshan LIU Yaguang DONG Wei | 2000 | Chinese Science Bulletin2000，45，5： | 3 |
| 19 | Quantum conductance of armchair carbon nanocoils: roles of geometry effects显示文摘Armchair carbon nanocoils (CNCs) with different geometric parameters are constructed and optimized using a tight-binding (TB) total energy model. The quantum conductance of these nanocoils is simulated employing a π-orbital TB model incorporated with the non-equilibrium Green's function theory. Compared with the perfect armchair carbon nanotubes (CNTs) and armchair CNTs with only Stone-Wales (SW) defects, the quantum conductance spectra of the armchair CNCs present distinct gaps around the Fermi level, which are mainly originated from the existence of sp3 carbon in the three-dimensional spiral structures. Moreover, the detailed conductance spectra of the armchair CNCs depend sensitively on their geometric parameters, such as tubular diameter and block-block distance. | LIU LiZhao GAO HaiLi ZHAO JiJun LU JianPing | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，5： | 3 |
| 20 | A fast,edge-preserving,distance-regularized model with bilateral filtering for oil spill segmentation of SAR images显示文摘Marine oil spills are among the most significant sources of marine pollution.Synthetic aperture radar(SAR)has been used to improve oil spill observations because of its advantages in oil spill detection and identification.However,speckle noise,weak boundaries,and intensity inhomogeneity often exist in the oil spill regions of SAR imagery,which will seriously aff ect the accurate identification of oil spills.To enhance marine oil spill segmentation of SAR images,a fast,edge-preserving framework based on the distance-regularized level set evolution(DRLSE)model was proposed.Specifically,a bilateral filter penalty term is designed and incorporated into the DRLSE energy function(BF-DRLSE)to preserve the edges of oil spills,and an adaptive initial box boundary was selected for the DRLSE model to reduce the operation time complexity.Two sets of RadarSat-2 SAR data were used to test the proposed method.The experimental results indicate that the bilateral filtering scheme incorporated into the energy function during level set evolution improved the stability of level set evolution.Compared with other methods,the proposed improved BF-DRLSE algorithm displayed a higher overall segmentation accuracy(97.83%).In addition,using an appropriate initial box boundary for the DRLSE method accelerated the global search process,improved the accuracy of oil spill segmentation,and reduced computational time.Therefore,the results suggest that the proposed framework is eff ective and applicable for marine oil spill segmentation. | Wandi WANG Hui SHENG Yanlong CHEN Shanwei LIU Jijun MAO Zhe ZENG Jianhua WAN | 2021 | Journal of Oceanology and Limnology2021，39，4： | 3 |
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