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94篇 您的检索式：作者名="LOURENCO R"

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	题名	作者	年代	出处	被引量
1	p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival显示文摘响应 DNA 损坏的房间命运的中央仲裁人是 p53,它调整涉及房间周期拘捕,幸存和 apoptosis 的基因的表示。尽管 DNA 损坏开始的许多回答被描绘了,肌动朊细胞骨架管理者的角色大部分是未知的。我们现在显示出那 RhoC 和秘鲁利玛机场之代号 kinase (LIMK2 ) 2 是 genotoxic 代理人导致的直接 p53 目标基因。尽管 RhoC 和 LIMK2 在肌动朊细胞骨架规定有生长得很好的角色,我们的结果显示 LIMK2 的激活也有支持幸存的功能追随者 DNA 损坏。由调停 siRNA 的击倒或选择的药理学封锁的 LIMK 抑制敏化房间到无线电 -- 或化疗,以便当与 LIMK 抑制结合了时,当单身地管理了时,是尚不致命的治疗导致了房间死亡。我们的调查结果建议把 LIMK 禁止者与 genotoxic 治疗相结合能比单个代理人的管理更有效,并且加亮在肌动朊细胞骨架管理者和 DNA 之间的一个新奇连接导致损坏的房间幸存机制。	Daniel R Croft Diane Crighton Michael S Samuel Filipe C Lourenco June Munro Jenifer Wood Karim Bensaad Karen H Vousden Owen J Sansom Kevin M Ryan Michael F Olson	2011	Cell Research2011，21，4：	3
2	Minimally invasive treat- ments for benign prostatic enlargement:systematic review of randomised controlled trials 显示文摘	Lourenco T Pickard R Vale L	2008	The British Medical Journal2008，337，7676：	1
3	Biomonitoring a human population inhabiting nearby a deactivated uranium mine显示文摘	Lourenco J Pereira R Pinto F	2013	Toxicology2013，305，：	1
4	Effect of combined ensiling of sorghum and soybean with or without molasses and lactobacilli on silage quality and in vitro rumen fermentation显示文摘	Lima R Lourenco M Diaz R F	2010	Animal Feed Science and Technology2010，155，2：	1
5	Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3 显示文摘	Chapman R S Lourenco P C Tonner E	1999	Genes Dev1999，13，19：	1
6	An efficient room-temperature silicon-based lightemitting diode显示文摘	Ng W L Lourenco M A Gwilliam R M Ledain S Shao G Homewood K P		0，，6825：	1
7	A new chance-constrained maximum capture location problem显示文摘	Colomé R Lourenco H R Serra D	2003	Annals of Operations Research2003，122，14：	1
8	Minimally invasive treatments for benign prostatic enlargement: systematic review of randomised controlled trials 显示文摘	Lourenco T Pickard R Vale L	2008	BMJ2008，337，：	1
9	Extraordinary opti- cal gain from silicon implanted with erbium显示文摘	Lourenco M A Gwilliam R M Homewood K P	2007	Appl Phys Lett2007，91，14：	1
10	@ Note:A workbench for Biomedical Text Mining显示文摘	Lourenco A Carreira R Carneiro S	2009	J Biomed Inform(S1532-0464)2009，42，4：	1
11	Information Needs of Recently Diagnosed Cancer Patients in Brazil显示文摘	Pinto R N Chaves A C Lourenco M T	2004	Int J Psychiatry Med2004，34，4：	1
12	Comparison of immune responses in mice infected with different strains of Strongyloides venezuelensis 显示文摘	MACHADO E R UETA M T LOURENCO E V	2007	Parasite Immunol2007，29，11：	1
13	Suppression of Epithelial Apoptosis and Delayed Mammary Gland Involution in Mice with a Conditional Knockout of Star3 显示文摘	CHAPMAN R S LOURENCO P C TONNER E	1999	Genes Dev1999，13，19：	1
14	An efficient room-temperature silicon-based light-emitting diode显示文摘	Ng W L Lourenco M A Gwilliam R M Ledain S Shao G Homewood K P		0，，6825：	1
15	Predictors of adverse outcome in a diabetic population following acute coronary syndromes显示文摘	Lourenco C António N Teixeira R		0，，03：	1
16	Adaptive compensation for detuning in pendulum tuned mass dampers 显示文摘	Roffel A J Lourenco R Narasimhan S	2011	Journal of Structure Engineering2011，137，：	1
17	Mutations in NR5A1 associated with ovarian insufficiency显示文摘	Lourenco D Brauner R Lin L	2009	N Engl J Med2009，360，12：	1
18	Multi Objective Meta-heuristcs for the Bus Driver Scheduling Problem显示文摘	Lourenco H R Paixao J P	2007	Transporttation Science2007，35，3：	1
19	Microarray analy- ses revealthat plant mutagenesis may induce more tran- scriptomic changesthan transgene insertion 显示文摘	Batista R Saibo N Lourenco T	2008	Proc Natl Acad Sci USA2008，105，36：	1
20	An efficient room-temperature silicon-based light-emitting diode显示文摘	NG W L LOURENCO M A GWILLIAM R M	2001	Nature2001，410，：	1

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