|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Concordance of non-invasive mechanical and serum tests for liver fibrosis evaluation in chronic hepatitis C显示文摘AIM To determine the sensitivity and specificity of liver stiffness measurement(LSM) and serum markers(SM) for liver fibrosis evaluation in chronic hepatitis C.METHODS Between 2012 and 2014,81 consecutive hepatitis C virus(HCV) patients had METAVIR score from liver biopsy compared with concurrent results from LSM [transient elastography(TE) [FibroS can~/ARFI technology(Virtual Touch~)] and SM [FIB-4/aspartate aminotransferase-toplatelet ratio index(APRI)].The diagnostic performance of these tests was assessed using receiver operating characteristic curves.The optimal cut-off levels of each test were chosen to define fibrosis stages F ≥ 2,F ≥ 3 and F = 4.The Kappa index set the concordance analysis.RESULTS Fifty point six percent were female and the median age was 51 years(30-78).Fifty-six patients(70%) weretreatment-na?ve.The optimal cut-off values for predicting F ≥ 2 stage fibrosis assessed by TE were 6.6 kP a,for acoustic radiation force impulse(ARFI) 1.22 m/s,for APRI 0.75 and for FIB-4 1.47.For F ≥ 3 TE was 8.9 kP a,ARFI was 1.48 m/s,APRI was 0.75,and FIB-4 was 2.For F = 4,TE was 12.2 kP a,ARFI was 1.77 m/s,APRI was 1.46,and FIB-4 was 3.91.The APRI could not distinguish between F2 and F3,P = 0.92.The negative predictive value for F = 4 for TE and ARFI was 100%.Kappa index values for F ≥ 3 METAVIR score for TE,ARFI and FIB-4 were 0.687,0.606 and 0.654,respectively.This demonstrates strong concordance between all three screening methods,and moderate to strong concordance between them and APRI(Kappa index = 0.507).CONCLUSION Given the costs and accessibility of LSM methods,and the similarity with the outcomes of SM,we suggest that FIB-4 as well as TE and ARFI may be useful indicators of the degree of liver fibrosis.This is of particular importance to developing countries. | Denise C Paranaguá-Vezozzo Adriana Andrade Daniel F C Mazo Vinicius Nunes Ana L Guedes Taisa G Ragazzo Renata Moutinho Lucas S Nacif Suzane K Ono Venancio A F Alves Flair J Carrilho | 2017 | World Journal of Hepatology2017，9，8： | 7 |
| 2 | Femtojoule electro-optic modulation using a silicon– organic hybrid device显示文摘Energy-efficient electro-optic modulators are at the heart of short-reach optical interconnects,and silicon photonics is considered the leading technology for realizing such devices.However,the performance of all-silicon devices is limited by intrinsic material properties.In particular,the absence of linear electro-optic effects in silicon renders the integration of energy-efficient photonic–electronic interfaces challenging.Silicon–organic hybrid(SOH)integration can overcome these limitations by combining nanophotonic silicon waveguides with organic cladding materials,thereby offering the prospect of designing optical properties by molecular engineering.In this paper,we demonstrate an SOH Mach–Zehnder modulator with unprecedented efficiency:the 1-mm-long device consumes only 0.7 fJ bit^(-1) to generate a 12.5 Gbit s^(-1) data stream with a bit-error ratio below the threshold for hard-decision forward-error correction.This power consumption represents the lowest value demonstrated for a non-resonant Mach–Zehnder modulator in any material system.It is enabled by a novel class of organic electro-optic materials that are designed for high chromophore density and enhanced molecular orientation.The device features an electro-optic coefficient of r33<180 pm V^(-1) and can be operated at data rates of up to 40 Gbit s^(-1). | Sebastian Koeber Robert Palmer Matthias Lauermann Wolfgang Heni Delwin L Elder Dietmar Korn Markus Woessner Luca Alloatti Swen Koenig Philipp C Schindler Hui Yu Wim Bogaerts Larry R Dalton Wolfgang Freude Juerg Leuthold Christian Koos | 2015 | Light(Science & Applications)2015，4，1： | 4 |
| 3 | On the Measurement of Stress-strain Curves by Spherical Indentation显示文摘 | E G Herbert G M Pharr W C Oliver B N Lucas J L Hay | 2001 | Thin Solid Films2001，，： | 1 |
| 4 | Multi-institutional validation of a symptom based classification for renal cell carcinoma 显示文摘 | JEAN-JACQUES P EMMANUELLE L LUCA C | 2004 | J Urol2004，172，： | 1 |
| 5 | A Dynamic Model for Plant Growth: A Simulation of Dry Matter Accumulation for Tobacco显示文摘 | WANN M PAPER C D LUCAS H L | 1978 | Photosynthetica1978，，12： | 1 |
| 6 | 查看详情显示文摘 | Marco de Lucas M C Fabreguette F Linsavanh M Imhoff L Heintz O Josse-Courty C Mesnier M T Potin V Bourgeois S Sacilotti M | | 0，，： | 1 |
| 7 | Poly ( ethylene-co-vinylacetate) ( EVA) as wax in hibit or of a Brazili an crude oil: oilviscosity, pour point and phase behavior of organic solutions 显示文摘 | Machado A L C Lucas E F Gonzalez G | 2001 | Journal of Petroleum Science and Engineering2001，32，234： | 1 |
| 8 | Determination of or- ganophosphorous flame reretardants in fish tissues by ma- trix solid- phase dispersion and gas chromatography 显示文摘 | Luca C Anna L P Conny O | 2010 | Anal Bioanal Chem2010，397，3： | 1 |
| 9 | Wear behaviour of thermally sprayed ceramic oxide coatings 显示文摘 | GIOVANNI B VALERIA C LUCA L | 2006 | Wear2006，261，1112： | 1 |
| 10 | Blueberry prevents bone loss in ovariectomized rat model of postmenopausal osteoporosis显示文摘 | Devareddy L Hooshmand S Collins J K Lucas E A Chai S C Arjmandi B H | 2008 | The Journal of nutritional biochemistry2008，19，10： | 1 |
| 11 | Surface analysis of Ni-Cr dental alloys显示文摘 | BUMGARDNER J D LUCAS L C | 1993 | Dental Materials1993，9，： | 1 |
| 12 | Magnetic properties of Co-P alloys electrodeposited at room temperature显示文摘 | Lucas I Perez L Aroca C | 2005 | Journal of Magnetism and Magnetic Materials2005，，： | 1 |
| 13 | Poly (ethylene-co-vinyl acetate)(EVA)as wax inhibitor of a Brazilian crude oil:Oil viscosity, pour point and phase behavior of organic solutions显示文摘 | MACHADO A L C LUCAS E F GONZáLEZ G | 2001 | Journal of Petroleum Science and Engineering2001，32，2： | 1 |
| 14 | Effects of metallic ion toxicity on human gingival fibroblasts morphology 显示文摘 | Messer R L W Bishop S Lucas L C | 1999 | Biomaterials1999，20，18： | 1 |
| 15 | The double yield in the tensile deformation of the polyethylenes 显示文摘 | Lucas J C Failla M D Smith F L | 1995 | Polymer Engineering and Science1995，35，13： | 1 |
| 16 | Influence of different agricultural practices (type of N-- fertilizer) on soil nitrous oxide emission显示文摘 | Henault C Devis X Lucas J L | 1998 | Biology and Fertility of Soils1998，27，： | 1 |
| 17 | Healthcare staff as promoters of parental presence at anesthetic induction:Net Promoter Score survey显示文摘BACKGROUND Surgical intervention is usually a traumatic event that causes stress and anxiety in the pediatric patient and the family environment.To reduce the harmful effects of presurgical anxiety,parental presence during induction of anesthesia(PPIA)is one of the more notable interventions used in medical centers.However,data on this measure are difficult to evaluate and often face resistance from healthcare staff.AIM To analyze the perception of the healthcare workers after the implementation of a PPIA program.METHODS A survey was developed and sent by email to all the healthcare staff working in the children’s area of a tertiary hospital.It consisted of 14 items divided into positive aspects of PPIA and negative aspects of PPIA evaluated with the use of a Likert scale(1 to 5).The demographics of the respondents were included in the data collected.The answers to the questions were interpreted through the Net Promoter Score(NPS).The statistical analysis compared the differences in the responses to each question of the survey made by the different groups of health personnel included.RESULTS A total of 141 surveys were sent out,with a response rate of 69%.Of the total number of responses,68%were from women and 32%from men.The average age of the participants was 42.3±10.6 years.As for the positive questions about the PPIA,83%had an NPS>50,and only one had a score between 0 and 50,which means that the quality of the service was rated as excellent or good by 100%of the respondents.On the other hand,100%of the negative questions about the PPIA had a negative NPS.Responses to the question“PPIA increases patient safety”were significantly different(P=0.037),with a lower percentage of pediatric surgeons(70%)thinking that PPIA increased patient safety,compared with anesthesiologists(90%),nursing(92%),and other medical personnel(96%).CONCLUSION The personnel who participated in the PPIA program at our center were in favor of implementation.There were no validated arguments to support worker resistance to the development of the PPIA. | María Velayos Karla Estefanía María Alvarez María C Sarmiento Lucas Moratilla Pascual Sanabria Francisco Hernández Manuel V López Santamaría | 2021 | World Journal of Clinical Pediatrics2021，10，6： | 1 |
| 18 | Post-deposition heat treatments for ion beam sputter deposited calcium phosphate coatings显示文摘 | Lucas L C | 1994 | Biomaterials1994，15，15： | 1 |
| 19 | Stent jack technique in stent assisted coiling of wide neck aneurysms显示文摘 | de Paula Lucas C Piotin M Spelle L | 2008 | Neurosurgery2008，62，52： | 1 |
| 20 | Poly(ethylene-co-vinyl acetate)(EVA)as wax inhibitor of a Brazilian crude oil:oil viscosity,pour point and phase behavior of organic solutions显示文摘 | ANDRE L C M ELIZABETE F Lucas GASPAR G | 2001 | Journal of Petroleum Science and Engineering2001，32，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员