|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa显示文摘Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV transmission.Methods:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July 2011.The HIV status of mothers was determined by rapid tests and EUSA.Discordant results were confirmed by real-time PCR.PCR was used to determine HIV status of children born from HIV-positive mothers.Results:Among 1 300 pregnant women tested for HIV,378 were seropositive.Mothers were predominantly housewives(69.7%),and their mean age was(28.32±0.15) years.The overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is effective.The rate of HIV vertical transmission is significantly reduced.Early diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina Faso.We also found that PCR is an effective tool to confirm HIV status in pregnant women. | Laure Stella Ghoma Linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 4 |
| 2 | High-Resolution Crystal Structure and Redox Properties of Chloroplastic Triosephosphate Isomerase from Chlamydomonas reinhardtii显示文摘Triosephosphate isomerase (TPI ) 催化 glyceraldehyde-3-phosphate 的互变现象到 dihydroxyacetone 磷酸盐。光合的有机体通常包含位于细胞质和叶绿体的 TPI 的二 isoforms。当细胞质的 TPI 涉及 glycolysis 时, chloroplastic isoform 参予 CalvinBenson 周期,为碳固定负责的一个关键光合的过程。与它的细胞质的对应物相比, chloroplastic TPI 的功能的特征糟糕被调查了,它的三维的结构没被解决。最近,几研究包括 dithiol/disulfide 交换, glutathionylation,和 nitrosylation 作为不同氧化还原作用修正的一个潜在的目标建议了 TPI。然而,在蛋白质活动的既不效果也不位于这些氧化还原作用修正下面的分子的机制被调查了。这里,我们 recombinantly 生产了并且从单细胞的绿水藻 Chlamydomonas reinhardtii (Cr ) 净化了 TPI。酶的生物化学的性质被描出,它的结晶的结构在 1.1 的一个决定是坚定的 ? 。CrTPI 是有包含典型(/)8 桶褶层的子单元的 homodimer。尽管为 TRX 规定的证据都没被获得, CrTPI 被发现由 nitrosoglutathione 由氧化谷胱甘肽和 trans-nitrosylation 经历 glutathionylation,证实它到多重氧化还原作用修正的敏感。 | Mirko Zaffagnini Laure Michelet Chiara Sciabolini Nastasia Di Giacinto Samuel Morisse Christophe H. Marchand Paolo Trost Simona Fermani Stephane D Lemaire | 2014 | Molecular Plant2014，7，1： | 4 |
| 3 | Albacore tuna catch distributions relative to environmental features observed from satellites显示文摘 | Laurs R M Fiedler P C Montgomery D R | 1984 | Deep-Sea Res1984，31，9： | 1 |
| 4 | Biomch anical aspects of fix ed br idge-w or k suppor ted by natur al teeth and endoesseous implants显示文摘 | Lundgr en D Laur ell L | 2000 | Per iodontology2000，4，1： | 1 |
| 5 | ABCB1 1199G>A genetic polymorphism(Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines显示文摘 | Ge'raldine D Laure E Nadtha P | 2014 | Plos One2014，9，3： | 1 |
| 6 | Albacore tuna catch distributions relative to environmental features observed from satellites显示文摘 | LAURS R M FIEDLER P C MONTGOMERY D R | 1984 | Deep Sea Research1984，31，9： | 1 |
| 7 | The impact of hyperglyce- mia on patients with severe brain injury 显示文摘 | Elan J Laure 1AO Michael D | 2005 | Trauma2005，58，1： | 1 |
| 8 | Albacore tuna catch distributions relative to environ mental features observed from satellites显示文摘 | LAURS R M FIEDLER P C MONTGOMERY D R | 1984 | Deep Sea Research Part A Oceanographic Research Papers1984，31，9： | 1 |
| 9 | Human immunodeficiency virus-driven expansion of CD4^+ CD25^+ Regulatory T cells Which Suppress HIV-specific CD4 T-cell Responses in H/V-infected Patients显示文摘 | Laurence W Vladimira D P Laure Ci | 2004 | Blood2004，104，： | 1 |
| 10 | Simultaneous determination of ' earthy-musty' odorous haloanisoles and their corresponding halophenols in water samples using solid-phase microextraction coupled to gas chromatography with electron-capture detection显示文摘 | Laure M Jose D Auguste B | 2003 | J Chromatogr A2003，999，： | 1 |
| 11 | ABCB1 1199G>A genetic polymorphism(Rs2229109) influences the intracellular accumulation of tacrolimus in HEK293 and K562 recombinant cell lines显示文摘 | Geraldine D Laure E Nadtha P | 2014 | PloS One2014，9，4： | 1 |
| 12 | Truth discovery and copying detection in a dynamic world显示文摘 | Dong X Laure B E Srivastava D | 2009 | Proceedings of the VLDB Endowment2009，，： | 1 |
| 13 | Hierarchical Splatting: A progressive refinement algorithm for volume rendering 显示文摘 | Laur D Hanrahan P | 1991 | Computer Graphics1991，25，4： | 1 |
| 14 | Extended-spectrum β- lactamases producing Enterobacteriaceae in community and private health care centers 显示文摘 | Corinne A Veronique D Laure C | 2003 | Antimic robi Agents Chemothera2003，47，11： | 1 |
| 15 | Impaired Myocardial Radial Function in Asymptomatic Patients with Type 2 Diabetes Mellitus: A Speckle-Tracking Imaging Study显示文摘 | Laura Ernande Ernst R. Rietzschel Cyrille Bergerot Marc L. De Buyzere Frédéric Schnell Laure Groisne Michel Ovize Pierre Croisille Philippe Moulin Thierry C. Gillebert Geneviève Derumeaux | 2010 | Journal of the American Society of Echocardiography2010，，12： | 1 |
| 16 | Intracellular clusterin causes juxtanuelear aggregate formation and mitochondrial alteration 显示文摘 | LAURE D JEAN-IUC V VINCENT R | 2003 | J Cell Sci2003，116，15： | 1 |
| 17 | Determinants of Smallholders' Decisions to Leave Land Fallow : The Case of Kosovo 显示文摘 | Johannes S Sophia D Laure L | 2012 | Journal of Agricultural Economies2012，，01： | 1 |
| 18 | Obesity, inflammatory markers,and endometrial cancer risk:a prospective case- control study 显示文摘 | Laure D Sabina R Susen B | 2010 | Endocrine-Related Cancer2010，17，： | 1 |
| 19 | ComparativeGenetic Mapping Between Octoploid and Diploid Fragaria SpeciesReveals a High Level of Colinearity Between Their Genomes and theEssentially Disomic Behavior of the Cultivated Octoploid Strawberry显示文摘 | Mathieu R G Estelle L K Laure B Sargent D J Monfort A Simpson D Arus P Guerin G Denoyes-Rothan B | 2008 | Genetics2008，179，： | 1 |
| 20 | Ignition and combustion of a packed bed in a stagnation point flow part Ⅱ: Heterogeneous and homogeneous reactions 显示文摘 | Reineh D Laurs A Adomeit G | 1998 | Combustion and Name1998，113，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员