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8篇 您的检索式:作者名="Lawrence Latour"
    题名 作者 年代 出处 被引量
1Whole-Brain Arterial Spin Labeling Perfusion MRI in Patients With Acute Stroke显示文摘Reinoud P.H. Bokkers Daymara A. Hernandez José G. Merino Raymond V. Mirasol Matthias J. van Osch Jeroen Hendrikse Steven Warach Lawrence L. Latour 2012Stroke2012,,5:1
2Pseudocontinuous Arterial Spin Labeling Quantifies Relative Cerebral Blood Flow in Acute Stroke显示文摘Daymara A. Hernandez Reinoud P.H. Bokkers Raymond V. Mirasol Marie Luby Erica C. Henning José G. Merino Steven Warach Lawrence L. Latour 2012Stroke2012,,3:1
3Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison显示文摘Julio A Chalela Chelsea S Kidwell Lauren M Nentwich Marie Luby John A Butman Andrew M Demchuk Michael D Hill Nicholas Patronas Lawrence Latour Steven Warach 2007The Lancet2007,,9558:1
4Predictors of acute stroke mimics in 8,187 patients referred to a stroke service显示文摘José G. Merino Marie Luby Richard Benson Lisa A. Davis Amie W. Hsia Lawrence L. Latour John K. Lynch Steven Warach 2013Journal of Stroke and Cerebrovascular Diseases2013,,:1
5Circulating immune cell landscape in patients who had mild ischaemic stroke显示文摘Introduction Patients who had a mild ischaemic stroke who present with subtle or resolving symptoms sometimes go undiagnosed,are excluded from treatment and in some cases clinically worsen.Circulating immune cells are potential biomarkers that can assist with diagnosis in ischaemic stroke.Understanding the transcriptomic changes of each cell population caused by ischaemic stroke is critical because they work closely in a complicated relationship.In this study,we investigated peripheral blood mononuclear cells(PBMCs)transcriptomics of patients who had a stroke using a single-cell RNA sequencing to understand peripheral immune response after mild stroke based on the gene expression in an unbiased way.Methods Transcriptomes of PBMCsfrom 10 patients who had an acute ischaemic stroke within 24 hours after stroke onset were compared with 9 race-matched/age-matched/gender-matched controls.Individual PBMCs were prepared with ddSeqTM(Illumina-BioRad)and sequenced on the Illumina NovaSeq 6000 platform.Results Notable population changes were observed in patients who had a stroke,especially in NK cells and CD14+monocytes.The number of NK cells was increased,which was further confirmed by flow cytometry.Functional analysis implied that the activity of NK cells also is enhanced in patients who had a stroke.CD14+monocytes were clustered into two groups;dendritic cell-related CD14+monocytes and NK cell-related CD14+monocytes.We found CD14+monocyte subclusters were dramatically reduced in patients who had a stroke.Discussion This is the first study demonstrating the increased number of NK cells and new monocyte subclusters of mild ischaemic stroke based on the transcriptomic analysis.Our findings provide the dynamics of circulating immune response that could assist diagnosis and potential therapeutic development of mild ischaemic stroke.Young-Eun Cho Hyangkyu Lee Heekyong R.Bae Hyungsuk Kim Sijung Yun Rany Vorn Ann Cashion Mary Jo Rucker Mariam Afzal Lawrence Latour Jessica Gill 2022Stroke & Vascular Neurology2022,7,4:1
6Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9显示文摘Taura L. Barr Lawrence L. Latour Kyung-Yul Lee Timothy J. Schaewe Marie Luby George S. Chang Ziad El-Zammar Shaista Alam John M. Hallenbeck Chelsea S. Kidwell Steven Warach 2010Stroke2010,,3:1
7Blood–Brain Barrier Disruption in Humans Is Independently Associated With Increased Matrix Metalloproteinase-9显示文摘Taura L. Barr Lawrence L. Latour Kyung-Yul Lee Timothy J. Schaewe Marie Luby George S. Chang Ziad El-Zammar Shaista Alam John M. Hallenbeck Chelsea S. Kidwell Steven Warach 2010Stroke2010,,3:1
8急性卒中影像学研究路径图Ⅱ显示文摘卒中影像学研究组(StrokeImagingResearchGroup,STIR)、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议,最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议(Stroke Treatment Academy Industry Roundtable,STAIR)期间举行。Max Wintermark Gregory W. Albers Joseph P. Broderick Andrew M. Demchuk Jochen B. Fiebach Jens Fiehler James C. Grotta Gary Houser Tudor G. Jovin Kennedy R. Lees Michael H. Lev David S. Liebeskind Marie Luby Keith W. Muir Mark W. Parsons Rudiger von Kummer Joanna M. Wardlaw Ona Wu Albert J. Yoo Andrei V. Alexandrov Jeffry R. Alger Richard I. Aviv Roland Bammer Jean-Claude Baron Fernando Calamante Bruce C.V. Campbell Trevor C. Carpenter Sφren Christensen William A. Copen Colin P. Derdeyn E. Clarke Haley Jr Pooja Khatri Kohsuke Kudo Maarten G. Lansberg Lawrence L. Latour Ting-Yim Lee Richard Leigh Weili Lin Patrick Lyden Grant Mair Bijoy IC Menon Patrik Michel Robert Mikulik Raul G. Nogueira Left φstergaard Salvador Pedraza Christian H. Riedel Howard A. Rowley Pina C. Sanelli Makoto Sasaki Jeffrey L. Saver Pamela W. Schaefer Peter D. Schellinger Georgios Tsivgoulis Lawrence R. Wechsler Philip M. White Greg Zaharchuk Osama O. Zaidat Stephen M. Davis Geoffrey A. Donnan Anthony J. Furlan Werner Hacke Dong-Wha Kang Chelsea Kidw ell Vincent N. Thijs Gotz Thomalla Steven J. Warach 严晓铭 刘牧 张晶晶 柯开富 2014国际脑血管病杂志2014,22,2:0
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