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| 1 | Six-minute walking test performance is associated with survival in cirrhotic patients显示文摘BACKGROUND Patients with cirrhosis are at risk of cirrhotic cardiomyopathy,with resulting cardiac dysfunction and exercise limitations.Six minute walking test(6MWT)assesses functional status and predicts morbidity and mortality in cardiopulmonary diseases.AIM To determine if it associates with mortality by analyzing 6MWT performance in patients with liver cirrhosis.METHODS A cohort of 106 cirrhotic patients was evaluated in the outpatient setting with echocardiogram and 6MWT and follow up for one year to document hepatic decompensation and mortality.The distance in meters was recorded at the end of 6 min(6MWD).RESULTS This cohort had a mean age of 51 years and 56%male;patients were staged as Child A in 21.7%,B 66%and C 12.3%.Walk distance inversely correlated with Child scores,and was significantly reduced as Child stages progresses.Patients who died(10.4%)showed shorter mean 6MWD(P=0.006).Low 6MWD was an independent predictor of mortality(P=0.01).CONCLUSION 6MWT is a noninvasive inexpensive test whose result is related to Child scores and mortality.It is useful to identify patients with liver cirrhosis at high risk of mortality for closer monitoring and potential early intervention. | Carolina Frade M G Pimentel Ana Cristina de Castro Amaral Adriano Miziara Gonzalez Michelle Lai Danielde Oliveira Mota Maria Lucia Gomes Ferraz Wilson Mathias Junior Mario Kondo | 2021 | World Journal of Hepatology2021，13，11： | 2 |
| 2 | Structure, expression, and activity of Tyro3,a neural adhesion-related receptor tyrosine kinase 显示文摘 | Lai C Gore M Lemke G | 1994 | Oncogene1994，9，： | 1 |
| 3 | Immunology and epilepsy显示文摘 | Najjar S Bembaum M Lai G | 2008 | Rev Neurol Dis2008，5，3： | 1 |
| 4 | Hypertension and risk of stroke recurrence显示文摘 | Alter M Friday G Lai SM | 1994 | Stroke1994，25，8： | 1 |
| 5 | Actuat显示文摘 | Wei B Y Hsu M C Su P G Lin H M Wu R J Lai H J Sensor | 2004 | B2004，101，： | 1 |
| 6 | Evaluation of solid phase extraction and gas chromatography for determination of cholesterol oxidation products in spray-dried whole egg显示文摘 | LAI S M J L G ZABIK M E | 1995 | Journal of Agricultural and Food Chemistry1995，43，5： | 1 |
| 7 | miR -34a inhibits migration and invasion by regulating the SIRT1/p53 pathway in human SW480 cells 显示文摘 | LAI M DU G SHI R | 2015 | Mol Med Rep2015，11，5： | 1 |
| 8 | Kallikreins on ste- roids: structure, function, and hormonal regulation of prostate - specific antigen and the extended kallikrein locus 显示文摘 | LAWRENCE M G LAI J CLEMENTS J A | 2010 | Endocr Rev2010，31，4： | 1 |
| 9 | A muhifactorial analysis of risk factors for recurrence of ischemic stroke 显示文摘 | Lai SM Alter M Friday G | 1994 | Stroke1994，25，5： | 1 |
| 10 | Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (eAAT3) interacting protein GTRAP3-18显示文摘 | BUTCHBACH M E R LAI L LIN C L G | 2002 | Gene2002，292，12： | 1 |
| 11 | Urinary expression of kidney injury markers in renal transplant recipients显示文摘 | Szeto C C Kwan B C Lai K B Lai F M Chow K M Wang G | 2010 | Clin J Am Soc Nephrol2010，5，： | 1 |
| 12 | A multifactorial analysis of risk factors for recurrence of ischemic stroke显示文摘 | Lai SM Alter M Friday G | 1994 | Stroke1994，25，5： | 1 |
| 13 | U-Pb zircon,geochemical and Sr-Nd-Hf isotopic constraints on the age and origin of Early Palaeozoic Ⅰ-type granite from the Tengchong-Baoshan Block,western Yunnan province,SW China显示文摘 | Liu S Hu R Z Gao S Feng C X Huang Z L Lai S C Yuan H L Liu X M Coulson I M Feng G Y Wang T and Qi Y Q | | 0，，： | 1 |
| 14 | Differential activation of ER stress and apoptosis in response to chronically elevated free fatty acids in pancreatic beta-cells 显示文摘 | Lai E Bikopoulos G Wheeler M B | 2008 | Am J Physiol Endocrinol Metab2008，294，3： | 1 |
| 15 | Coronavirus as a possible cause of severe acute respiratory syndrome 显示文摘 | Peiris G S Lai S T Poon L L M Guan Y | 2003 | Lancet2003，8，： | 1 |
| 16 | Hypertension and risk of stroke recurrence显示文摘 | Alter M Friday G Lai SM | 1994 | Stroke1994，25，8： | 1 |
| 17 | Salinity effect on mechanical dewatering of sludge with and without chemical conditioning 显示文摘 | LoI M C Lai K C K Chen G H | 2001 | Environmental Science & Technology2001，35，25： | 1 |
| 18 | Immunology and epilepsy显示文摘 | Najjar S Bernbaum M Lai G | 2008 | Rev Neurol Dis2008，5，3： | 1 |
| 19 | Evaluation of microbial trans glutaminase and ribose cross-linked soy protein isolate based mi crocapsules containing fish oil显示文摘 | Chee Y G Lai H C Azhar M I | 2008 | Innovative Food Science and Emerging Technologies2008，，9： | 1 |
| 20 | Separation of xylene isomer vapors with oriented MFI membranes made by seeded growth显示文摘 | Xomeritakis G Lai Zhiping Tsapatsis M | 2001 | Ind Eng Chem Res2001，40，： | 1 |
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