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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Biomass production potentials in Central and Eastern Europe under different scenarios显示文摘 | Van DAM J FAAIJ A P C LEWANDOWSKI L FISCHER G | 2007 | Biomass Bioenergy2007，31，6： | 1 |
| 3 | Galileo/SAR: performance aspects and new service capabilities显示文摘 | Lewandowski A Niehoefer B and Wietfeld C | 2010 | International Journal of Satellite Communications and Networking2010，28，6： | 1 |
| 4 | Genotypic variation in cold tolerance influences the yield of Miscanthus 显示文摘 | Farrell A D Clifton-Brown J C Lewandowski I | 2006 | Annals of applied biology2006，149，3： | 1 |
| 5 | A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells显示文摘 | WILLIAMS C EDVARDSSON K LEWANDOWSKI S A | 2008 | Oncogene2008，27，7： | 1 |
| 6 | Galileo/ SAR:Performance Aspects and New Service Capabilities 显示文摘 | LEWANDOWSKI A NIEHOEFER B WIETFELD C | 2010 | International Journal of Satellite Communications and Networking2010，28，6： | 1 |
| 7 | Tobacco mosaic virus inoculation inhibits wound-induced Jasmonic acid-mediated responses within but not between plants显示文摘 | Preston C A Lewandowski C Enyedi A J | 1999 | Planta1999，209，： | 1 |
| 8 | A ge- nome-wide study of the repressive effects of estrogen recep- tor beta on estrogen receptor alpha signaling in breast canc- er cells 显示文摘 | Williams C Edvardsson K Lewandowski S A | 2008 | Oncogene2008，27，7： | 1 |
| 9 | Segregation to SiC/Al interfaces in Al based metal matrix composites 显示文摘 | Hippsely C A Lewandowski J J | 1990 | Scripta Metall Mater1990，25，： | 1 |
| 10 | Fundamental denitrifieation kinetics studied with Pseudomonas denitrificans 显示文摘 | Wang J H Baltzis B C Lewandowski G A | 1995 | Biotechnol Bioeng1995，47，1： | 1 |
| 11 | Evidence for organosulfates in secondary organic aerosol 显示文摘 | Surratt J D Kroll J H Kleindienst T E Edney E O Claeys M Sorooshian A Ng N L Offenberg J H Lewandowski M Jaoui M Flagan R C Seinfeld J H | 2007 | Environ Sci Technol2007，41，2： | 1 |
| 12 | Kinetic study of the hydrodenitrogenation of carbazoleover bulk molybdenum carbide显示文摘 | Lewandowski M Sayag C | 2003 | Journal of Catalysis2003，218，： | 1 |
| 13 | Genotypic variation in cold tolerance influences yield of Miscanthus 显示文摘 | Farrell A D Clifton-Brown J C Lewandowski I etal | 2006 | Annals of Applied Biology2006，149，3： | 1 |
| 14 | Genotypic variation in cold tolerance influences the yield of Miscanthus显示文摘 | Farrell A D Clifton-Brown J C Lewandowski I | 2006 | Annals of Applied Biology2006，149，3： | 1 |
| 15 | A genome-wide study of the repressive effects of estrogen receptor beta on estrogen receptor alpha signaling in breast cancer cells 显示文摘 | Williams C Edvardsson K Lewandowski S A | 2008 | Oncogene2008，27，7： | 1 |
| 16 | Miscanthus: European experience with a novel energy crop显示文摘 | Lewandowski I Clifton-Brown J C Scurlock ] M O et a l | 2000 | Bi- omass and Bioenergy2000，19，4： | 1 |
| 17 | Emissions and risks associated with oxyfuel combustion: State of the science and critical data gaps 显示文摘 | Senior C L Morris W Lewandowski T A | 2013 | Journal of the Air & Waste Management Association2013，63，7： | 1 |
| 18 | A bottom-up assessment and review of global bio-energy potentialsto 2050显示文摘 | Smeets E M W Faaij A P C Lewandowski I M | 2007 | Progr Energy Combust Sci2007，33，1： | 1 |
| 19 | Low-temperature luminescence properties of CaSO4 : Dy 显示文摘 | Barkyoumb J H Mathur V K Lewandowski A C | 1997 | Journal of Luminescence1997，7274，： | 1 |
| 20 | Combined intravenous and intra-arterial r-TPA versus intra-arterial therapy of acute ischemic stroke: Emergency Management of Stroke (EMS) Bridging Trial显示文摘 | Lewandowski C A Frankel M Tomsick T A | 1999 | Stroke1999，30，： | 1 |
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