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| 1 | 表示心室复极不一致的有效参数的研究显示文摘采用二次样条小波变换提取心电信号的特征点 ,并通过分析羊心脏表面 64通道的心电信号 ,研究心肌缺血前后的兴奋恢复间隔 ( Activation- recovery interval,ARI)及其离散度的变化 ,发现当缺血造成心室复极不一致增大时 ,心脏表面的平均 ARI没有明显的变化 ,而 ARI离散度明显增加 ( 5 9.9ms vs12 6.3 ms,P=0 .0 0 0 7) ,进一步的计算机模拟证明 ARI接近动作电位时程 ,表明 | 李川勇 贾林壮 Lexin Wang | 2001 | 生物医学工程学杂志2001，18，4： | 3 |
| 2 | Use of microbial fuel cells to monitor current production in Qi-deficient liver cells显示文摘OBJECTIVE:To monitor current production in Qi-deficient liver cells,and to study how cellular proton leakage might affect electric current production.METHODS:Cells were placed in an microbial fuel cells(MFC)anode and the electric current was measured.Mitochondrial-affecting chemicals,2,4-dinitrophenol(DNP)and resveratrol(RVT),were used to induce proton leakage in cells and their effect on current production observed.MCF-7 breast cancer cells exhibited higher proton leakage relative tonormal liver cells.A mouse model for Qi-deficiency was prepared according to the Methodology of Animal Experiment in Chinese medicine.The Qi-tonics Buzhongyiqi Tang(BZYQT),which is used to treat the Qi-deficiency condition,was applied to Qi-deficient liver cells to examine how current production was altered.RESULTS:Adding either DNP or RVT to normal liver cells increased current production.MCF-7 cells that possessed high proton leakage were also found to produce higher currents than normal liver cells.Higher current production,lower cellular glucose content,and lower adenosine triphosphate(ATP)production rate were found in Qi-deficient liver cells,in which the use of DNP or RVT further increased current production.The use of BZYQT to treat Qi-deficient liver cells decreased current production,counteracted the action of DNP,and also improved cellular glucose content.CONCLUSION:High electric current production was found in liver cells with high cellular proton leakage.Positive current responses to both mitochondria-affecting chemicals,DNP and RVT,appeared to indicate proper mitochondrial function.The high proton leakage detected in Qi-deficient liver cells might have caused high energy losses,which served to explain the observed lower cellular glucose content and ATP production rate than in normal cells.These results might also explain the exhibited syndromes of low energy and fatigue in Qi-deficient patients.Proton leakage,induced by DNP or the Qi-deficient condition,was possibly caused by unusual uncoupling of oxidative phosphorylation and appeared to be inhibited by treatment with BZYQT,such that decreased current pro-duction was observed after BZYQT treatment. | Karen Poon Liang Lexin Xu Chang Wang Ruihua | 2016 | Journal of Traditional Chinese Medicine2016，36，2： | 1 |
| 3 | Digoxin may reduce the mortality rates in patients witt, congestive heart failure显示文摘 | Lexin Wang Shukai Song | 2005 | Medical Hypot heses2005，64，： | 1 |
| 4 | Silver Nanoparticles Supportedby Novel Nickel Metal-Organic Frameworks: An Efficient HeterogeneousCatalyst for an A3 Coupling Reaction显示文摘 | Sujing Wang Xiaoxiao He Lexin Song Zhiyong Wang | 2009 | Synlett2009，，03： | 1 |
| 5 | Left cardiac sympathetic denervation as the first-line therapy for congenital long QT syndrome显示文摘 | Lexin Wang Guoqin Feng | 2004 | Medical Hypotheses2004，，3： | 1 |
| 6 | Prognostic Value of B-type Natriuretic Peptide in Patients with Acute Coronary Syndromes显示文摘 | Tongwen Sun Lexin Wang Yanzhou Zhang | 2006 | Archives of Medical Research2006，，4： | 1 |
| 7 | Zirconium Doped Hydrotalcite-based NiAl Mixed Oxides——Enhanced Performance for Adsorption of SO2 and NO显示文摘In the present study, the adsorptive behavior of zirconium doped hydrotalcite-based NiAl mixed oxides for reducing NO and SO2 was compared. According to tlie experimental results, the Zr^4+ cations were partially dissolved in crystalline NiO phase. With the addition of Zr, new centers for oxygen release and storage were formed, Lewis acid strength increased, and weakly and strongly alkaline sites were expanded. Moreover, in situ FTIR(Fourier transfonn infrared spectroscopy) investigation demonstrated that the amounts of surface bisulfite, sulfite, nitrite and nitrate spe? cies ofZrNiAlO were much more than those ofNiAlO. On the whole, this study concluded that the addition of Zr^4+ to NiAlO works to improve this compound as major absorbent for SO2 and NO. | ZHAO Ling ZHANG Yu LI Lexin XING Yating WANG Shuai Christopher J. MARTYNIUK | 2019 | Chemical Research in Chinese Universities2019，35，3： | 0 |
| 8 | 心室复极空间不一致性表示方法的探讨显示文摘本文采用二次样条小波变换提取心电信号的特征点 ,从羊心脏表面 6 4通道的心电信号中 ,提取各通道的QT间隔和兴奋恢复间隔 (ARI) ,分别求出二者以极差法、标准差法和变异系数定义的离散度 ,通过统计检验P值 ,比较三种方法定义的QT和ARI离散度在心肌缺血前后的变化 .发现三种定义的QT离散度 ,在心肌缺血前后都不具有显著性差异 ,并以变异系数离散度的P值最大 .而心肌缺血使得ARI离散度明显增加 ,三种定义的ART离散度在心肌缺血前后都具有显著性差异 ,以变异系数离散度的P为最小 ,可见三种方法定义的离散度均有效 ,而变异系数离散度较极差法。 | 李川勇 贾林壮 Wang Lexin | 2001 | 南开大学学报(自然科学版)2001，34，4： | 0 |
| 9 | Propofol terminates ventricular fibrillation storm caused by pulmonary embolism显示文摘To the editor:In March 2009,a 56-year-old woman was referred to our hospital for chest discomfort that had lasted for 12 hours.ECG revealed frequent ventricular premature beats and a complete right bundle branch block.Serum CK and cardiac troponin I was normal.Serum biochemistry and blood gas analysis were unremarkable. | Hong Jiang Xu Mengdan Kong Ailing Liu Qiang Chen Rong Dai Qiuyan Wang Lexin Sun Baogui | 2014 | Chinese Medical Journal2014，，21： | 0 |
| 10 | A three-pulmonary vein isolation approach to treat paroxysmal atrial fibrillation显示文摘Objective To investigate the safety and efficacy of a 3-pulmonary vein (PV) isolation approach in treating paroxysmal atrial fibrillation (AF). Methods Radiofrequency catheter ablation was used to eliminate PV potential in 11 patterns with frequent paroxysmal AF refractory to anti-arrhythmic agents. During sinus rhythm, PV potential was mapped in the left and right superior PVs and left inferior PV. The procedural success was defined as the elimination of PV potential in the 3 PVs. Restults PV potential was identified and abolished in a total of 24 PVs, mostly in the left and right superior PV. There was no pulmonary stenosis or other complications during or after the procedures. AF recurred in one patient after an average of 12 ± 3 month follow-up. Conclusions PV potemials were present mostly in the left or right superior PV. The 3-PVs isolation approach is safe and effective in preventing drug-resistant paroxysmal AF. | Lexin WANG | 2004 | Journal of Geriatric Cardiology2004，1，1： | 0 |
| 11 | Epidemiology and prevention of adverse drug reactions in the elderly显示文摘Many studies have demonstrated a correlation between increasing age and adverse drug reactions. This increased risk is related to aged-related changes in pharmacokinetics and pharmacodynamics. In addition, chronic illnesses such as congestive heart failure, coronary artery disease and hypertension are more prevalent in the elderly who also have an increased risk of diabetes, arthritis and cancer. Consequently elderly patients are often treated with multiple medications, which may cause drug interactions and adverse drug reactions. Adequate undergraduate training in clinical pharmacology and continued professional development in evidence-based therapeutics will undoubtedly reduce inappropriate prescribing and improve the quality of medications. Good communications between physicians and patients are also critically important in avoidance or prevention of adverse drug reactions in the elderly. | Lexin WANG | 2005 | Journal of Geriatric Cardiology2005，2，4： | 0 |
| 12 | Related factors of dilated cardiomyopathy显示文摘目的将在中国病人调查病原学和扩大心肌症(DCM ) 的相对因素。盒子控制研究被进行与稳定的心绞痛(控制组) 在高发生的区域(案例组) 和 150 个病人把 233 个病人与 DCM 作比较的方法。疾病信息的生活方式和历史被询问表收集;人的反心肌的抗体 IgG (AMA- IgG ) ,人的 Coxsackie B 病毒 IgG (CBV- IgG ) 和人的侵入人体气管粘膜的病菌抗体 IgG (副词 -- lgG ) 与 ELISA 被测量。来自高、低的流行区域和浆液踪迹元素的饮料水里的一般化学、毒物学的指示物也被比较。结果 1 ) 与控制组,相比,案例组有更多的农民(P < 0.01 ) ,与低平均收入(P < 0.01 ) ,更高的白酒消费(P < 0.01 ) 并且心肌炎的历史的更高的发生(P < 0.01 ) 。2 ) AMA-IgG, CBV-IgG 和 ADV-IgG 层次是低的,有 DCM 的病人的积极的率 ofAMA-IgG, CBV-IgG 和 ADV-IgG 是分别地 7.78% , 6.67% 和 6.67% ,在控制组与那些作比较的没有统计意义。3 ) 铁的内容(1.36? | Guangyong Huang Hang Gao Xiangang Meng Zhonghua Yan Xiangquan Kong Lexin Wang | 2009 | Journal of Geriatric Cardiology2009，6，2： | 0 |
| 13 | Multivessel coronary artery ectasia and severe calcification in a patient with pheochromocytoma:a case report显示文摘Multivessel coronary artery ectasia with severe calcification is rare among patients with coronary artery disease. A 74-year-old Chinese woman suffered from acute myocardial infarction on a background of 50 years of poorly controlled hypertension secondary to pheochromocytoma, which was surgically removed in June 2012 prior to the presentation. Coronary angiography revealed total occlusion of the proximal left anterior descending artery, and multiple ectasias with severe calcification in the left main, circumflex and right coronary artery. After an aspiration thrombectomy and balloon angioplasty, grade 3 coronary flow was restored in the left descending coronary artery. No cardiac events were found in the 12-month follow-up. We conclude that multivessel coronary artery ectasia and severe calcification may be present in patients with a long-standing history of hypertension secondary to pheochromocytoma. | Daokuo Yao Xiangyu Gao Huiqiang Zhao Hui Chen Lexin Wang | 2019 | The Journal of Biomedical Research2019，33，1： | 0 |
| 14 | 先天性长QT综合征的基础与临床研究进展显示文摘 | 王乐华 Lexin Wang | 2005 | 山东医药2005，45，13： | 0 |
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