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| 1 | Specific grinding energy and surface roughness of nanoparticle jet minimum quantity lubrication in grinding显示文摘Nanoparticles with the anti-wear and friction reducing features were applied as cooling lubricant in the grinding fluid. Dry grinding, flood grinding, minimal quantity of lubrication(MQL), and nanoparticle jet MQL were used in the grinding experiments. The specific grinding energy of dry grinding, flood grinding and MQL were 84, 29.8, 45.5 J/mm^3, respectively. The specific grinding energy significantly decreased to 32.7 J/mm^3 in nanoparticle MQL. Compared with dry grinding, the surface roughness values of flood grinding, MQL, and nanoparticle jet MQL were significantly reduced with the surface topography profile values reduced by 11%, 2.5%, and 10%,respectively, and the ten point height of microcosmic unflatness values reduced by 1.5%, 0.5%,and 1.3%, respectively. These results verified the satisfactory lubrication effects of nanoparticle MQL. MoS_2, carbon nanotube(CNT), and ZrO_2 nanoparticles were also added in the grinding fluid of nanoparticle jet MQL to analyze their grinding surface lubrication effects. The specific grinding energy of MoS_2 nanoparticle was only 32.7 J/mm^3, which was 8.22% and 10.39% lower than those of the other two nanoparticles. Moreover, the surface roughness of workpiece was also smaller with MoS_2 nanoparticle, which indicated its remarkable lubrication effects. Furthermore,the role of MoS_2 particles in the grinding surface lubrication at different nanoparticle volume concentrations was analyzed. MoS_2 volume concentrations of 1%, 2%, and 3% were used.Experimental results revealed that the specific grinding energy and the workpiece surface roughness initially increased and then decreased as MoS_2 nanoparticle volume concentration increased.Satisfactory grinding surface lubrication effects were obtained with 2% MoS_2 nanoparticle volume concentration. | Zhang Dongkun Li Changhe Jia Dongzhou Zhang Yanbin Zhang Xiaowei | 2015 | Chinese Journal of Aeronautics2015，28，2： | 10 |
| 2 | Experimental verification of nanoparticle jet minimum quantity lubrication effectiveness in grinding显示文摘 | Dongzhou Jia Changhe Li Dongkun Zhang Yanbin Zhang Xiaowei Zhang | 2014 | Journal of Nanoparticle Research2014，，12： | 1 |
| 3 | Experimental Evaluation of MoS 2 Nanoparticles in Jet MQL Grinding with Different Types of Vegetable Oil as Base Oil显示文摘 | Yanbin Zhang Changhe Li Dongzhou Jia Dongkun Zhang Xiaowei Zhang | 2014 | Journal of Cleaner Production2014，，： | 1 |
| 4 | Safe and simplemethod of subtotal thyroidectomy显示文摘 | Li Dongkun Wang Mingjun Zhang Qingsong | 2009 | Clinical medi- cine of China2009，25，3： | 1 |
| 5 | Effects of Different Fertilization Measures on Chemical Composition and Quality of Flue-cured Tobacco显示文摘[Objectives]The paper was to obtain fertilizer varieties and fertilization techniques that meet the special nutritional requirements of characteristic tobacco varieties in Mengyin tobacco area.[Methods]With the local main plant variety NC102 as the test material,the effects of combined application,dosage and application methods of different types of organic fertilizers,compound fertilizers and potassium fertilizers on chemical composition and quality of NC102 flue-cured tobacco leaves were studied.[Results]Under the premise of reducing the amount of fertilizer applied,the slow-release integrated fertilizer increased the sugar-alkali ratio and potassium-chloride ratio,and reduced the sulfur content of tobacco leaves,but it did not significantly improve the sensory quality of tobacco leaves.Increasing the application of organic fertilizer made the sugar-alkali ratio and potassium-chloride ratio more coordinated,reduced the sulfur content and improved the sensory quality of tobacco leaves.Microbial agents significantly increased the sugar-alkali ratio in tobacco leaves,and had obvious effects of increasing potassium and reducing chlorine.Different types and application methods of potassium fertilizers had obvious effects on sensory quality of tobacco leaves.Increasing the application amount of potassium fertilizer and later topdressing significantly improved the potassium content and sensory quality of tobacco leaves.[Conclusions]The study provides a basis for balanced fertilization in characteristic flue-cured tobacco production in Mengyin tobacco area. | Zhongwen ZHANG Linda LI Cheng ZHANG Weimin WANG Tao ZHANG Changhe CHENG Dongkun WANG Xiaoqiang WANG | 2022 | Plant Diseases and Pests2022，13，4： | 0 |
| 6 | M1 macrophage-related gene model for NSCLC immunotherapy response prediction显示文摘Patients diagnosed with non-small cell lung cancer(NSCLC)have a limited lifespan and exhibit poor immunotherapy outcomes.M1 macrophages have been found to be essential for antitumor immunity.This study aims to develop an immunotherapy response evaluation model for NSCLC patients based on transcription.RNA sequencing profiles of 254 advanced-stage NSCLC patients treated with immunotherapy are downloaded from the POPLAR and OAK projects.Immune cell infiltration in NSCLC patients is examined,and thereafter,different coexpressed genes are identified.Next,the impact of M1 macrophage-related genes on the prognosis of NSCLC patients is investigated.Six M1 macrophage coexpressed genes,namely,NKX2-1,CD8A,SFTA3,IL2RB,IDO1,and CXCL9,exhibit a strong association with the prognosis of NSCLC and serve as effective predictors for immunotherapy response.A response model is constructed using a Cox regression model and Lasso Cox regression analysis.The M1 genes are validated in our TD-FOREKNOW NSCLC clinical trial by RT-qPCR.The response model shows excellent immunotherapy response prediction and prognosis evaluation value in advanced-stage NSCLC.This model can effectively predict advanced NSCLC prognosis and aid in identifying patients who could benefit from customized immunotherapy as well as sensitive drugs. | Sifan Wu Qiqi Sheng Pengjun Liu Zhe Jiao Jinru Lv Rong Qiao Dongkun Xie Zanhan Wang Jiamei Ge Penghui Li Tiaoxia Wei Jie Lei Jieyi Fan Liang Wang | 2024 | Acta Biochimica et Biophysica Sinica2024，56，3： | 0 |
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