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| 1 | Effect of extrusion speed on microstructure and mechanical properties of the Mg-Ca binary alloy显示文摘This work reported the effect of extrusion speeds on the microstructures and mechanical properties of Mg-Ca binary alloy.The results showed that yield strength of the as-extruded Mg-1.2wt.%Ca alloys decrease from∼360MPa to∼258MPa as the ram speed increases from 0.4mm/s to 2.4 mm/s,and the elongation increases from∼3.9%to∼12.2%.The microstructure changes from bimodal grain feature to the complete dynamical recrystallization(DRX)with increase of the extrusion speed.The ultrafine DRXed grains in size of∼0.85μm,the numerous nano-Mg_(2)Ca particles dispersing along the grain boundaries and interiors,as well as the high density of residual dislocations,should account for the high strength.It is believed that the high degree of dynamic recrystallization and the resulting texture randomization play the critical roles in the ductility enhancement of the high-speed extruded Mg alloys. | Jingren Li Aiyue Zhang Hucheng Pan Yuping Ren Zhuoran Zeng Qiuyan Huang Changlin Yang Lifeng Ma Gaowu Qin | 2021 | Journal of Magnesium and Alloys2021，9，4： | 9 |
| 2 | Mechanical stress distribution and risk assessment of 110 kV GIS insulator considering Al_(2)O_(3)settlement显示文摘The growing application of gas insulated switchgear(GIS)in electric power system asks for higher reliability of epoxy(EP)insulators,thus it is important to seek effective methods to improve the operating reliability of GIS insulators.On the basis of the 110 kV GIS insulator,this study studied the aluminium oxide(Al_(2)O_(3))settlement in the curing process and the stress distribution of the horizontally laid GIS.Besides,the risk coefficient was defined to evaluate the operating reliability of insulators laid by different methods(I-V).Some conclusions are shown below:the Al_(2)O_(3)settlement in the curing process causes the insulator density to have a large variation from 2.13 to 2.32 g/cm^(3).The Al_(2)O_(3)content has a great influence on the mechanical performances of EP/Al_(2)O_(3)system.The first principle stress is localised on the upper interface between the insulator and the conductor,which is the main threat to the mechanical damage of insulator.The laying method V appears to be optimal with a pretty low risk coefficient of 31.5.In actual application,for the horizontally laid GIS,the insulator should be laid with the mould gate downward to improve its mechanical reliability. | Hucheng Liang Boxue Du Jin Li Zehua Wang | 2019 | High Voltage2019，4，1： | 5 |
| 3 | Promising functional graded materials for compact gaseous insulated switchgears/pipelines显示文摘The electric field distributions along gas-solid interfaces determine the reliability,lifetimes and sizes of gaseous insulated switchgears/pipelines(GIS/GIL),which also affect the reliability of power systems.In this study,the characteristics of steady and transient electric field distributions were first introduced,followed by the concept of functionally graded materials(FGMs).The development histories of FGM applied in electrical engineering and the related optimisation methods were described in detail.The field regulation effect and fabrication technology of different FGM insulators were also compared.To overcome the limitations of traditional FGM insulators,the design of surface FGM(SFGM)was proposed,together with their preparation methods and electrical performance.Furthermore,the future development prospects of FGM and SFGM insulators for compact GIS/GIL were summarised. | Jin Li Hucheng Liang Yun Chen Boxue Du | 2020 | High Voltage2020，5，3： | 5 |
| 4 | Low-cost and high-strength Mg-Al-Ca-Zn-Mn wrought alloy with balanced ductility显示文摘A novel low-cost Mg-Al-Ca-Zn-Mn-based alloy was developed to simultaneously improve its strength and ductility.The high yield strength of 411 MPa and the high elongation to failure of~8.9%have been achieved in the as-extruded Mg-1.3Al-1.2Ca-0.5Zn-0.6Mn(wt%)sample.Microstructure characterizations showed that the high strength is mainly associated with the ultra-fined dynamically recrystallized(DRXed)grains.Moreover,high-density dislocations in the un-DRXed region and nano-precipitates are distributed among theα-Mg matrix.The high ductility property can be ascribed to the high volume fraction of DRXed grains with a much randomized texture,as well as the formations of high-density subgrains in the un-DRXed grain regions. | Kun Yang Hucheng Pan Sen Du Man Li Jingren Li Hongbo Xie Qiuyan Huang Huajun Mo Gaowu Qin | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，7： | 3 |
| 5 | Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis显示文摘Vascular smooth muscle cell (vSMC) is highly plastic as its phenotype can change in response to mechanical cues inherent to the extracellular matrix (ECM). VSMC may be activated from its quiescent contractile phenotype to a proinflammatory phenotype, whereby the cell secretes chemotactic and inflammatory cytokines, e.g. MCP1 and IL6, to functionally regulate monocyte and macrophage infiltration during the development of various vascular diseases including arteriosclerosis. Here, by culturing vSMCs on polyacrylamide (PA) substrates with variable elastic moduli, we discovered a role of discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase that binds collagens, in mediating the mechanical regulation of vSMC gene expression, phenotype, and proinflammatory responses. We found that ECM stiffness induced DDR1 phosphorylation, oligomerization, and endocytosis to repress the expression of DNA methyltransferase 1 (DNMT1), very likely in a collagen-independent manner. The DDR1-to-DNMT1 signaling was sequentially mediated by the extracellular signal-regulated kinases (ERKs) and p53 pathways. ECM stiffness primed vSMC to a proinflammatory phenotype and this regulation was diminished by DDR1 inhibition. In agreement with the in vitro findings, increased DDR1 phosphorylation was observed in human arterial stiffening. DDR1 inhibition in mouse attenuated the acute injury or adenine diet-induced vascular stiffening and inflammation. Furthermore, mouse vasculature with SMC-specific deletion of Dnmt1 exhibited proinflammatory and stiffening phenotypes. Our study demonstrates a role of SMC DDR1 in perceiving the mechanical microenvironments and down-regulating expression of DNMT1 to result in vascular pathologies and has potential implications for optimization of engineering artificial vascular grafts and vascular networks. | Jin Wang Si-an Xie Ning Li Tao Zhang Weijuan Yao Hucheng Zhao Wei Pang Lili Han Jiayu Liu Jing Zhou | 2022 | Bioactive Materials2022，7，11： | 3 |
| 6 | Dynamic Response of Double-Sided Loess Slope under Vehicle Load显示文摘In order to verify and study the dynamic response law on the double-sided loess slope under the action of the waves generated by automobile traffic,we select a double-sided loess slope from the long section of Anzi Road as the research object.Both field investigations and on-site monitoring processes are conducted,for the purpose of providing robust basis for road protection in these conditions.In detail,vehicleinduced vibration signals are different according to different vehicle types,speeds,as well as positions,and thus are collected,respectively.Based on the statistical analysis of the signals,the vibration response law and frequency spectrum characteristics of the slope are summarized.The results show that:①The dynamic response of the doublesided loess slope increases as the vehicle load increases,and the strong vibration response area is located in the middle of the side slope;②When the vehicle load is small,the vibration wave amplification effect is obvious.On the contrary,when the vehicle load is large,the vibration wave amplification effect is weakened;③The spectrum distribution of the X-direction wave is single-peak shape,and the dominant frequency is concentrated in 30-50 Hz;the frequency spectrum distribution of the Zdirection wave shows a multi-peak shape,and the dominant frequency is concentrated in 20-180 Hz;④The vibration wave propagates in the slope.The frequency change shows little correlation with the type,speed and position of the vehicle,and instead,it is mainly determined by the slope itself.This study reveals the dynamic response on doubled-sided loess slopes and provides both theoretical and practical significance for the road protection in such situations. | LI Peng YANG Hucheng SU Shengrui LIU Xiang | 2020 | Earthquake Research in China2020，34，4： | 2 |
| 7 | Piezo1 regulates migration and invasion of breast cancer cells via modulating cell mechanobiological properties显示文摘Cell migration and invasion are two essential processes during cancer metastasis. Increasing evidence has shown that the Piezo1 channel is involved in mediating cell migration and invasion in some types of cancers. However, the role of Piezo1 in the breast cancer and its underlying mechanisms have not been clarified yet. Here, we show that Piezo1 is high-expressed in breast cancer cell (BCC) lines, despite its complex expression in clinical patient database. Piezo1 knockdown (Piezo1-KD) promotes unconfined BCC migration, but impedes confined cell migration. Piezo1 may mediate BCC migration through the balances of cell adhesion, cell stiffness, and contractility. Furthermore, Piezo1-KD inhibits BCC invasion by impairing the invadopodium formation and suppressing the expression of metalloproteinases (MMPs) as well. However, the proliferation and cell cycle of BCCs are not significantly affected by Piezo1. Our study highlights a crucial role of Piezo1 in regulating migration and invasion of BCCs, indicating Piezo1 channel might be a new prognostic and therapeutic target in BCCs. | Yang Yu Xiao’an Wu Sisi Liu Hongping Zhao Bo Li Hucheng Zhao Xiqiao Feng | 2021 | Acta Biochimica et Biophysica Sinica2021，53，1： | 2 |
| 8 | Aggregation Behavior of Imidazolium-Based Ionic Liquids in Water显示文摘 | Hucheng Zhang Huijun Liang Jianji Wang Kun Li | 2007 | Zeitschrift für Physikalische Chemie2007，，8： | 1 |
| 9 | Carbon monoxide augments electrical signaling in cultured neural networks of hippocampal neurons partly through activation of BKCa channels显示文摘 | Hucheng Zhao Bailin Liu Quanyou Zhang Xiao'an WU Yang Yu Forrest Fabian Jesse Luming Li | 2015 | Acta Biochimica et Biophysica Sinica2015，47，5： | 1 |
| 10 | ZenLDA: Large-Scale Topic Model Training on Distributed Data-Parallel Platform显示文摘Recently, topic models such as Latent Dirichlet Allocation(LDA) have been widely used in large-scale web mining. Many large-scale LDA training systems have been developed, which usually prefer a customized design from top to bottom with sophisticated synchronization support. We propose an LDA training system named ZenLDA, which follows a generalized design for the distributed data-parallel platform. The novelty of ZenLDA consists of three main aspects:(1) it converts the commonly used serial Collapsed Gibbs Sampling(CGS) inference algorithm to a Monte-Carlo Collapsed Bayesian(MCCB) estimation method, which is embarrassingly parallel;(2)it decomposes the LDA inference formula into parts that can be sampled more efficiently to reduce computation complexity;(3) it proposes a distributed LDA training framework, which represents the corpus as a directed graph with the parameters annotated as corresponding vertices and implements ZenLDA and other well-known inference methods based on Spark. Experimental results indicate that MCCB converges with accuracy similar to that of CGS, while running much faster. On top of MCCB, the ZenLDA formula decomposition achieved the fastest speed among other well-known inference methods. ZenLDA also showed good scalability when dealing with large-scale topic models on the data-parallel platform. Overall, ZenLDA could achieve comparable and even better computing performance with state-of-the-art dedicated systems. | Bo Zhao Hucheng Zhou Guoqiang Li Yihua Huang | 2018 | Big Data Mining and Analytics2018，1，1： | 1 |
| 11 | Achieving high strength above 400 MPa in conventionally extruded Mg-Ca-Zn ternary alloys显示文摘In this work,the role of Zn content in modifying the microstructure and mechanical properties of the Mg-1.2Ca-xZn(x=0.6,2.0 wt.%,named as XZ10-0 and ZX21-0,respectively)based alloys was studied,and it is found that the yield strength(YS)of the present Mg-(Zn)-Ca based alloys increases monotonically with increasing the Zn concentration,from~339 MPa in low-Zn content XZ10-0 sample to~406 MPa in high-Zn content ZX21-0 sample.Microstructure characterization shows that the enhanced YS can be attributed to the grain refinement,fine and dispersed nano-phases,a large number of lamellae structures,and the decrease of recrystallization fraction.TEM results show that the formation mechanism for the ultra-fine grains in present Mg-(Zn)-Ca based alloys can be attributed to the co-segregation of Ca and Zn elements at the grain boundary,as well as the dynamic nanoprecipitations.When the Zn content is high,the nano-phases in ZX21-0 sample belong to the Ca;Mg;Zn;ternary phases,which exert much higher thermal stability than the nano-sized Mg2 Ca binary phases formed in the low-Zn content XZ10-0 sample.The finer size and higher number density of the nano-Mg Zn Ca phases lead to the much finer grain size and sub-grain lamellae thickness in ZX21-0 sample,which thus results in the higher YS of~406 MPa. | DU Sen YANG Kun LI Man LI JingRen REN YuPing HUANG QiuYan PAN HuCheng QIN GaoWu | 2022 | Science China(Technological Sciences)2022，65，3： | 1 |
| 12 | Construction of the recellularized corneal stroma using porous acellular corneal scaffold显示文摘 | Jianhui Xiao Hucheng Duan Zhao Liu Zheng Wu Yuqing Lan Wei Zhang Chaoyang Li Fen Chen Qiang Zhou Xiaoran Wang Junqi Huang Zhichong Wang | 2011 | Biomaterials2011，，29： | 1 |
| 13 | Health status assessment of axial piston pump under variable speed显示文摘The axial piston pump usually works under variable speed conditions.It is important to evaluate the health status of the axial piston pump under the variable speed condition.Aiming at the characteristic signals obtained under different wear levels of the port plate,a feature signal extraction method under variable speed conditions is proposed.Firstly,the combination of complete ensemble empirical mode decomposition with adaptive noise(CEEMDAN)energy spectrum and fast spectral kurtosis principle is used to accurately extract the intrinsic mode function(IMF)component containing the sensitive information of the degraded feature.Then,the aspect ratio analysis method of the angle domain variational mode decomposition(VMD)is used to process the feature index containing the sensitive information of the degraded feature.In order to evaluate the health status of the axial piston pump under variable speed,the vibration reliability analysis method for axial piston pump based on Weibull proportional failure rate model is proposed.The experimental results show that the proposed method can accurately evaluate the health status of the axial piston pump. | 郭锐 Li Hucheng Zhao Zhiqian Zhang Rongbing Zhao Jingyi Gao Dianrong | 2020 | High Technology Letters2020，26，3： | 0 |
| 14 | Two-dimensional interface superstructures assembled by well-ordered solute atoms显示文摘Segregation of solutes/impurities in the interfaces plays a decisive role in material performances.However,the segregation of solutes/impurities remains elusive due to the diversity of interfacial structures.Here,in a Mg-Nd-Mn ternary model system,two ordered novel two-dimensional(2D)interfacial superstructures formed by periodic segregation of solute atoms in special symmetric and asymmetric tilt grain boundaries(GBs)have been systematically investigated.Z-Contrast high-angle annular dark-field scanning transmission electron microscopy(HAADF-STEM)observations provided the atomic-level details on how solute atoms were arranged on these special partially coherent tilt GBs.The strained conditions of each atomic site at the tilt GBs were accurately reproduced by molecular dynamics(MD)simulations plus Voronoi analysis,and the rationality of solute segregation in each atomic-site was evaluated carefully based on the first-principles calculations.These findings expand our knowledge of solute/impurity segregation behaviors in the interfaces,especially the co-segregation behaviors in multi-component materials. | Peijun Yang Shanshan Li Hongbo Xie Jianfeng Jin Chuangwei Liu Hucheng Pan Yuping Ren Weitao Jia Yaping Zong Gaowu Qin | 2023 | Journal of Materials Science & Technology2023，，11： | 0 |
| 15 | Optimisation of superplastic processing parameters for (Cu_(43)Zr_(48)Al_9)_(98)Y_2 bulk metallic glasses显示文摘In this study,hot compression tests of (Cu_(43)Zr_(48)Al_9)_(98)Y_2 bulk metallic glasses (BMGs) were performed,and their micro structure and thermal properties after the deformation were studied to explore the appropriate range of their optimum processing parameters. The experimental results show that the superplastic deformation of (Cu_(43)Zr_(48)Al_9)_(98)Y_2 bulk metallic glasses depends mainly on the temperature and strain rate. It is suitable for superplastic processing when the alloys are in the state of Newtonian flow and do not crystallise. The appropriate processing parameters of (Cu_(43)Zr_(48)Al_9)_(98)Y_2 BMGs are the temperatures and strain rates, which are below the 'dividing line'. And when the temperature is above733 K, the strain rate must be>1×10^(-3) s^(-1). | Bing Li Xuanxuan Xu Hucheng Zhang Ke Yang Xinhui Fan Jinshan Li | 2019 | Journal of Rare Earths2019，37，1： | 0 |
| 16 | Natural Sesquiterpenoids, Diterpenoids, Sesterterpenoids, and Triterpenoids with Intriguing Structures from 2017 to 2022显示文摘This review covers the isolation,structural determination,plausible biosynthetic pathways,and biological activities of 166 natural terpenoids including 57 sesquiterpenoids,65 diterpenoids,15 sesterterpenoids,and 29 triterpenoids from January 2017 to December2022. | Xiaotian Zhang Meijia Zheng Aimin Fu Qin Li Chunmei Chen Hucheng Zhu Yonghui Zhang | 2023 | Chinese Journal of Chemistry2023，41，22： | 0 |
| 17 | Regulated adsorption-diffusion and enhanced charge transfer in expanded graphite cohered with N,B bridge-doping carbon patches to boost K-ion storage显示文摘The great challenges are remained in constructing graphite-based anode with well built-in structures to accelerate kinetics and enhance stability in the advanced K-ion batteries(KIBs).Here,we firstly report the design of expanded graphite cohered by N,B bridge-doping carbon patches(NBEG)for efficient K-ion adsorption/diffusion and long-term durability.It is the B co-doping that plays a crucial role in maximizing doping-site utilization of N atoms,balancing the adsorption-diffusion kinetics,and promoting the charge transfer between NBEG and K ions.Especially,the robust lamellar structure,suitable interlayer distance,and rich active sites of the designed NBEG favor the rapid ion/electron transfer pathways and high K-ion storage capacity.Consequently,even at a low N,B doping concentration(4.36 at%,2.07 at%),NBEG anode shows prominent electrochemical performance for KIBs,surpassing most of the advanced carbon-based anodes.Kinetic studies,density functional theory simulations,and in-situ Raman spectroscopy are further performed to reveal the K-ion storage mechanism and confirm the critical actions of co-doping B.This work offers the new methods for graphite-electrode design and the deeper insights into their energy storage mechanisms in KIBs. | Haiyan Wang Haowen Du Hucheng Zhang Songjie Meng Zhansheng Lu Hao Jiang Chunzhong Li Jianji Wang | 2023 | Journal of Energy Chemistry2023，，1： | 0 |
| 18 | Improved space charge transport model in bilayer dielectrics—considering carrier dynamic equilibrium显示文摘The Maxwell–Wagner model and bipolar charge transport model both aim at describing the charge transport behaviours in dielectrics.The Maxwell–Wagner model performs well in calculating the polarisation current and electric field distribution,but it is too macroscopic to describe the microscopic behaviours of space charges.The bipolar charge transport model can well simulate the space charge accumulation,but it cannot quantitatively relate the microscopic transport behaviours with the macroscopic conductivities of dielectrics.Considering the shortages of the above two models,an improved charge transport model,named carrier dynamic equilibrium model,was proposed in this study to simulate the polarisation process of the low-density polyethylene/ethylene propylene diene monomer bi-layer dielectric by introducing a source term of carrier dynamic equilibrium.Effects of carrier mobility and non-equilibrium carrier lifetime on the simulation results were explored,and a comparison among the results of measurement and different models was also made.Compared with the Maxwell–Wagner model and bipolar charge transport model,the improved model has the best coincidence with measurements,which can provide an accurate reference for the design of high-voltage direct current insulation systems. | Hucheng Liang Boxue Du Jin Li Hang Yao Zehua Wang | 2020 | High Voltage2020，5，2： | 0 |
| 19 | Study on non-uniformity and dynamic fracture characteristics of GIL tri-post insulators considering Al_(2)O_(3) sedimentation显示文摘Tri-post insulators in gas-insulated transmission line(GIL)are usually fabricated with high mass fraction of micron aluminum oxide(Al_(2)O_(3)),which will unavoidably settle under the action of gravity during the preparation process and seriously affect the uniformity.A model of filler sedimentation in epoxy resin composite materials was proposed based on the particle size analysis and Stokes'Law.Some scaled tri-post insulators were prepared and tested by slicing.It is determined that the position of density concentration is the lower side of the two lower posts and the upper interface between the insulator and the conductor.The density ranges from 2.144 to 2.346 g/cm^(3).The dynamic fracture simulation model of insulator was established and it is found that the insulator fracture occurs at the interface of upper post/insert under radial load,which is verified by experiments.By comparing the influence of sprue position on the density distribution,it is found that the uniformity of insulators is increased by 13.7% by forward pouring compared with reverse pouring.This research develops an accurate method for simulating the filler sedimentation and the fracture process in epoxy-based insulators,which is helpful for the improvement of mechanical reliability of GIL. | Jin Li Songtao Liu Hucheng Liang Liucheng Hao Yaxiang Wang Boxue Du | 2023 | High Voltage2023，8，4： | 0 |
| 20 | Front-end readout electronics system of ProtoDUNE-SP LAr TPC显示文摘Purpose As a prototype of Deep Underground Neutrino Experiment far detector,ProtoDUNE single-phase Liquid Argon(LAr)Time Projection Chamber(TPC)sits in H4 beam line at CERN to characterize detector response.It consists of 6 full-size Anode Plane Assemblies(APAs)plus 18 Cathode Plane Assembly(CPA)modules to form two 3.6-m drift regions with a total of 15,360 readout channels.To achieve a good signal-to-noise ratio with this noble liquid detector(770ton LAr),cold electronics developed at BNL for extremely low temperature(77K–89K)operation is an optimal solution,which decouples the electrode and cryostat design from the readout design.Methods With CMOS front end ASICs integrated with the TPC electrodes,the electronic noise is independent of the fiducial volume and much lower than with readout electronics at room temperature.In addition,signal digitization and multiplexing to high-speed links inside the cryostat result in large reduction in the quantity of cables and the number of cryostat penetrations,giving the designers of both the TPC and the cryostat the freedom to choose the optimum configurations.Results and conclusions By April 2018,we have successfully instrumented 6 APAs with cold electronics,and the results of the integration test before the final installation in the cryostat look very promising. | Hans-Gerd Berns Hucheng Chen Alessio D’Andragora Jack Fried Daniel Gastler S.Gao Eric Hazen Wenbin Hou Shaorui Li Feng Liu Veljko Radeka Maura Spanu Emerson Vernon Elizabeth Worcester Matthew Worcester Krithika Yethiraj Bo Yu Junbin Zhang | 2019 | Radiation Detection Technology and Methods2019，3，3： | 0 |
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