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| 1 | Investigation on the co-infections of Toxoplasma gondii with PRRSV, CSFV or PCV-2 in swine in part of China显示文摘The objective of the present investigation was to estimate the prevalence of Toxoplasma gondii infection and co-infection with porcine reproductive and respiratory syndrome virus(PRRSV), classical swine fever virus(CSFV) and porcine circovirus type 2(PCV-2) in pigs in China. A total of 372 tissues or serum samples collected from pigs distributed in 9 provinces/municipalities of China during the period from February 2011 to November 2012 were assayed for T. gondii antigens and antibodies using enzyme linked immunosorbent assay(ELISA) technique, while the PCR was designed for the detection of the PRRSV, CSFV and PCV-2, respectively. The total positive rate of T. gondii, PRSSV, CSFV and PCV-2 was 9.14%(34/372), 50.00%(186/372), 37.10%(138/372) and 3.23%(12/372), respectively. Among the 34 T. gondii positive samples, 26 samples were simultaneously infected with T. gondii and viruses, while the remaining eight samples were infected with T. gondii alone. In addition, the co-infection rate of T. gondii with PRSSV, T. gondii with PRSSV and CSFV, T. gondii with PRSSV and PCV-2, T. gondii with CSFV and PCV-2, T. gondii with PRSSV, CSFV and PCV-2 was 1.61%(6/372), 4.03%(15/372), 0.27%(1/372), 0.27%(1/372) and 0.81%(3/372), respectively. The results of the present survey revealed that PRRSV and CSFV were the common pathogens co-existing with porcine toxoplasmosis in China, and both of them could increase the chances of T. gondii infection in pig. This is the first report of T. gondii co-infections with viruses in pigs. It is very important to understand the interactions of parasite and virus, and can be used as reference data for the control and prevention of co-infections of T. gondii and viruses in pigs. | WANG Shuai ZHANG Meng LIU Xin-chao LIN Tao YANG Han-chun YUAN Shi-shan ZHAO Guang-wei IA Hassan YAN Ruo-feng SONG Xiao-kai XU Li-xin LI Xiang-rui | 2015 | Journal of Integrative Agriculture2015，14，9： | 2 |
| 2 | The relationship between cell proliferation, Cl^- secretion, and renal cyst growth: a study using CFTR inhibitors 显示文摘 | Li H Findlay IA Sheppard DN | 2004 | Kidney Int2004，66，5： | 1 |
| 3 | Type I strain of Toxoplasma gondii from chicken induced different immune responses with that from human,cat and swine in chicken显示文摘In this study,four strains of Toxoplasma gondii with the same genetic type(Type I) originated from chicken,human,cat and swine were used to compare the immune responses in resistant chicken host to investigate the relationships between the parasite origins and the pathogenicity in certain host.A total of 300,10-day-old chickens were allocated randomly into five groups which named JS(from chicken),CAT(from cat),CN(from swine),RH(from human) and a negative control group(—Ve) with 60 birds in each group.Tachyzoites of four different T.gondii strains(JS,CAT,CN and RH) were inoculated intraperitoneally with the dose of 1×10~7 in the four designed groups,respectively.The negative control(-Ve) group was mockly inoculated with phosphate-buffered saline(PBS) alone.Blood and spleen samples were obtained on the day of inoculation(day 0) and at days 4,11,25,39 and 53 post-infection to screen the immunopathological changes.The results demonstrated some different immune characters of T.gondii infected chickens with that of mice or swine previous reported.These differences included up-regulation of major histocompatibility complex class Ⅱ(MHC Ⅱ) molecules in the early stage of infection,early peak expressions of interleukin(IL)-12(IL-12) and-10(IL-10) and long keep of IL-17.These might partially contribute to the resistance of chicken to T.gondii infection.Comparisons to chickens infected with strains from human,cat and swine,chickens infected with strain from chicken showed significant high levels of CD4^+ and CD8^+ T cells,interferon gamma(IFN-γ),IL-12 and IL-10.It suggested that the strain from chicken had different ability to stimulate cellular immunity in chicken. | ZHAO Guang-wei WANG Shuai WANG Wang ZHANG Zhen-chao XIE Qing ZHANG Meng IA Hassan YAN Ruo-feng SONG Xiao-kai XU Li-xin LI Xiang-rui | 2015 | Journal of Integrative Agriculture2015，14，5： | 1 |
| 4 | MiR-223 suppresses cell proliferation by targeting IGF-IR 显示文摘 | Ia CY Li HH Zhu XC | 2011 | PLoS One2011，6，27： | 1 |
| 5 | Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin显示文摘 | Li B Yuan M Kim IA | 2004 | Oncogene2004，23，26： | 1 |
| 6 | Protein that binds fatty acids (I-FABP)--a new perspective evidence {or injury of the small intestine显示文摘 | Drozdov VN Li IA Varvanina GG | 2011 | Eksp Klin Gastroenterol2011，，5： | 1 |
| 7 | Papilin in development:a pericellular protein with a homology to the ADAMTS metalloproteinases显示文摘 | Kramerova IA Kawaguchi N Fessler LI | 2000 | Development2000，127，24： | 1 |
| 8 | Genetic pathways and mutation profiles of human cancers:site-and exposure-specific patterns显示文摘 | Lea IA Jackson MA Li X | 2007 | Carcinogenesis2007，28，9： | 1 |
| 9 | Surviving blood loss without fluid resuscitation christian shults显示文摘 | Sailhamer IA Li YQ | 2008 | J Trauma2008，64，3： | 1 |
| 10 | Novel pH-sensitive chitosan-derived micelles loaded with paclitaxel显示文摘 | Liu J ia Li Hongxia Jiang Xiaoqun | 2010 | Carbo- hydrate Polymers2010，82，2： | 1 |
| 11 | Mutant epidermal growth factor receptor displays increased signaling through the phosphatidylinositol-3 kinase/AKT pathway and promotes radioresistance in cells of astrocytic origin显示文摘 | Li B Yuan M Kim IA | | 0，，： | 1 |
| 12 | IrO2/SnO2 electrodes:prepared by sol-gel process and their electrocatalytic for pyrocatechol 显示文摘 | Liu Y IA Z Y Li J H | 2004 | Acta Materialia2004，52，： | 1 |
| 13 | Jones oxidation and high performance liquid chromatographic analysis of cholesterol in biologi- cal samples 显示文摘 | Jun Dong Wenxiang Chen Shu Wang Jiangtao Zhang Hongx- ia Li Hanhang Guo Yong Man Baosheng Chen | 2007 | Journal of Chromatography B2007，，： | 1 |
| 14 | What Triggers Top Turnovers in Management China 显示文摘 | Peter Cheng Jack L Li Wilson IA S | 2008 | Journal of Contemporary Accounting & Economics2008，14，1： | 1 |
| 15 | Microstructure and phase consti- tution near interface of Cu/Al vacuum brazing 显示文摘 | Ia C Z Li Y J Wang J | 2007 | Materials Science and Technology2007，23，7： | 1 |
| 16 | A new adaptive median filtering based on multidireetional eriterion显示文摘 | Li Li IA Xiuhua | 2008 | IEEE International Con- ferenee on Multimedia and lnformation Technology2008，，150： | 1 |
| 17 | Determination of carbaryl and its me- taholite 1-naphthol in water samples by fluorescence spectro- photometer after anionic surfactant micelle-mediated extraction with sodium dodecylsulfate显示文摘 | J IA G LI L QIU J | 2007 | Spectrochimica Acta Part A2007，67，2： | 1 |
| 18 | Increased endo-plasmic reticulum stress in decidual tissue from pregnan-cies complicated by fetal growth restriction with andwithout pre-eclampsia 显示文摘 | IA Li an ML0set SB Mundal | 2011 | Placenta2011，32，11： | 1 |
| 19 | Genetic pathways and mutation profiles of human cancers: site- and exposure-specific patterns显示文摘 | Lea IA Jackson MA Li X | 2007 | Carcinogenesis2007，28，9： | 1 |
| 20 | Nutrition and growth in relation to severity of renal disease in children 显示文摘 | Norman LI Coleman JE Macdonald IA | 2000 | Pediatr Nephrol2000，15，34： | 1 |
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