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| 1 | The characteristics of CO_2 assimilation of photosynthesis and chlorophyll fluorescence in transgenic PEPC rice显示文摘With PEPC, PPDK, NADP-ME and PEPC+ PPDK transgenic and untransformed rice (Orysa sativa L.), the activities of related C4 photosynthesis enzymes, the chlorophyll fluorescence parameters, CO2 exchange and other physiological indexes were compared, in which the physiological characteristics of PEPC transgenic rice were mainly studied. The results were as follows: (i) The activities of PEPC in PEPC transgenic rice were 20-fold higher than those in untransformed rice; the light-saturation photosynthetic rates and the carboxylation efficiency of PEPC transgenic rice were increased by 55% and 50% more than those of untransformed rice, respectively, while the CO2 compensation point decreased by 27%. (ii) The PS II photochemical efficiency (Fv/Fm) and photochemical quenching (qp) of transgenic PEPC rice decreased less in comparison with those of untransformed rice after the treatment with high light intensity (3 h) or methyl viologen (MV), a photooxidative reagent, which demonstrated that the tolerance of PEPC | JIAO Demao, LI Xia, HUANG Xueqing, CHI Wei, KUANG Tingyun & Ku SB Maurice1. Institute of Agrobiological Genetics and Physiology, Jiangsu Academy of Agricultural Sciences, Nangjing 210014, China 2. Institute of Botany, the Chinese Academy of Sciences, Beijing 100093, China 3. Botany Department, Washington State University, Pullman, WA 99164-4236, USA | 2001 | Chinese Science Bulletin2001，46，13： | 29 |
| 2 | 3′-Daidzein sulfonate sodium improves mitochondrial functions after cerebral ischemia/reperfusion injury显示文摘3′-Daidzein sulfonate sodium is a new synthetic water-soluble compound derived from daidzein(an active ingredient of the kudzu vine root). It has been shown to have a protective effect on cerebral ischemia/reperfusion injury in rats. We plan to study the mechanism of its protective effect. 3′-Daidzein sulfonate sodium was injected in rats after cerebral ischemia/reperfusion injury. Results showed that 3′-daidzein sulfonate sodium significantly reduced mitochondrial swelling, significantly elevated the mitochondrial membrane potential, increased mitochondrial superoxide dismutase and glutathione peroxidase activities, and decreased mitochondrial malondialdehyde levels. 3′-Daidzein sulfonate sodium improved the structural integrity of the blood-brain barrier and reduced blood-brain barrier permeability. These findings confirmed that 3′-daidzein sulfonate sodium has a protective effect on mitochondrial functions after cerebral ischemia/reperfusion injury, improves brain energy metabolism, and provides protection against blood-brain barrier damage. | Wa Yuan Qin Chen Jing Zeng Hai Xiao Zhi-hua Huang Xiao Li Qiong Lei | 2017 | Neural Regeneration Research2017，12，2： | 10 |
| 3 | Oroclinal bending and block rotations in South China since the Mesozoic——Geological and paleomagnetic evidence显示文摘THE South China Block exhibits a complex structural pattern in its Neoproterozoic-Mesozoic sedimentary cover. The lack of knowledge about the formation of this pattern hinders our understanding of the regional tectonic evolution and paleogeography, and the reconstruction of Phanerozoic apparent polar wander path(s). In this note we present a synthesis based on a paleomagnetic and tectonic analysis, which suggests that (i) the structural pattern over | LI Zhengxiang, FANG Dajun, Christopher McA. Powell and LOU Gang1. Department of Geology and Geophysics, The University of Western Australia, Nedlands WA 6907, Australia 2. Department of Earth Sciences, Zhejiang University, Hangzhou 310027, China | 1997 | Chinese Science Bulletin1997，42，2： | 7 |
| 4 | Would integrated Western and traditional Chinese medicine have more benefits for stroke rehabilitation? A systematic review and meta-analysis显示文摘Background Stroke is a major cause of death or long-term disability worldwide.Many patients with stroke receive integrative therapy consisting of Western medicine(WM)and routine rehabilitation in conjunction with Chinese medicine(CM),such as acupuncture and Chinese herbal medicine.However,there is no available evidence on the effectiveness of the combined use of WM and CM interventions in stroke rehabilitation.Aims The purpose of this meta-analysis is to evaluate the results of all individual studies to assess the combined use of CM and WM in stroke rehabilitation compared with WM only.Methods The Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines were followed.MEDLINE,EMBASE,Cochrane and China National Knowledge Infrastructure(CNKI)were searched.The included outcomes were dependency,motor function,depression and swallowing function.Subgroup analysis was performed,and publication bias was assessed using funnel plots.Summary of review 58 studies and 6339 patients were included in the meta-analysis.Subgroup analysis revealed that combined therapy comprising both acupuncture and WM had a superior effect on improving dependency and swallowing function compared with standard WM therapy alone.Potential superiority of combined therapy comprising CM and WM in improving depression compared with standard WM therapy was also found.Conclusions Our results indicate that the combined use of CM and WM could be more efficacious in stroke rehabilitation compared with the use of WM therapy alone.However,most studies were short in duration(2 to 4 weeks)and prone to different types of biases,which prevents making any conclusion regarding the long-term effects and raises concerns regarding true efficacy in context of high likelihood of Hawthorn bias.So,more randomised controlled trials with more rigorous design and longer duration of treatment and follow-up need to be conducted to compare WM alone versus WM and CM combined. | Linda LD Zhong Ya Zheng Alexander Y Lau Norman Wong Liang Yao Xingyao Wu Tengteng Shao Zhenxing Lu Huijuan Li Chun Sum Yuen Jianwen Guo Suzanne Lo Janita Chau Kam Wa Chan Bacon Fung Leung Ng Zhaoxiang Bian Edwin Chau-leung Yu | 2022 | Stroke & Vascular Neurology2022，7，1： | 7 |
| 5 | Factors associated with delayed intracerebral hemorrhage after superficial temporal artery-middle cerebral artery bypass in stenoocclusive cerebrovascular diseases显示文摘 | MaoZQ YuXG Li M Li WA | 2014 | Chinese Medical Journal2014，，4： | 6 |
| 6 | Challenges and strategies in high-accuracy manufacturing of the world’s largest SiC aspheric mirror显示文摘In the process of manufacturing the world’s largest silicon carbide(SiC)aspheric mirror,the primary difficulties are mirror blank preparation,asphere fabrication,and testing,as well as cladding and coating.Specifically,the challenges include the homogeneity of the complicated structure casting,accuracy and efficiency of the fabrication process,print-through effect,fidelity and precision of test procedure,stress and denseness of cladding process,the dynamic range of interferometric measurement,and air turbulence error due to the long optical path.To break through such a barrier of difficulties,we proposed the water-soluble room temperature vanishing mold and gel casting technology,homogeneous microstructure reaction-formed joint technology,nano-accuracy efficient compound fabrication,gravity unloading technology,high-denseness low-defect physical vapor deposition(PVD)Si-cladding technology,test data fusion method,and time-domain averaging method,etc.Based on the proposed technologies and methods,we have accomplished the world’s largest SiC aspheric mirror with a size of φ4.03 m.The impressive performance of the SiC aspheric mirror is validated by the characteristics of the fabricated SiC aspheric mirror.The aerial density of the SiC blank is less than 120 kg/m^(2),surface shape test accuracy is better than 6 nm RMS,thickness inhomogeneity of the cladding layer is less than 5%,and the final surface figure error and roughness are 15.2 nm RMS and 0.8 nm RMS,respectively. | Xuejun Zhang Haixiang Hu Xiaokun Wang Xiao Luo Ge Zhang Wenxing Zhao Xiaoyi Wang Zhenyu Liu Ling Xiong Erhui Qi Congcong Cui Yanchao Wang Yingjie Li Xu Wang Longxiang Li Yang Bai Qiang Cheng Zhiyu Zhang Ruigang Li Wa Tang Xuefeng Zeng Weijie Deng Feng Zhang | 2022 | Light(Science & Applications)2022，11，12： | 3 |
| 7 | Formation mechanisms of heavy oils in the Liaohe Western Depression,Bohai Gulf Basin显示文摘The Liaohe Oilfield in the Liaohe Western Depression of the Bohai Gulf Basin is the third-largest oil producing province and the largest heavy oil producing oilfield in China. A total of 65 oil samples,35 rock samples and 36 reservoir sandstone samples were collected and analyzed utilizing conventional geochemical and biogeochemical approaches to unravel the mechanisms of the formation of the heavy oils. Investigation of the oils with the lowest maturity compared with the oils in the Gaosheng and Niuxintuo oilfields indicates no apparent relation between the maturity and physical properties of the heavy oils. It is suggested that the heavy oil with primary origin is not likely the main mechanism re-sponsible for the majority of the heavy oils in the Liaohe Western Slope. The absence and/or depletion of n-alkanes etc.,with relatively low molecular weight and the occurrence of 25-norhopane series in the heavy oils as well as the relatively high acidity of the oils all suggest that the majority of the heavy oils once experienced secondary alteration. The fingerprints of the total scanning fluorescence (TSF) of the inner adsorbed hydrocarbons on the reservoir grains and the included hydrocarbons in fluid inclusions are similar to that of the normal oils in the area but are different from the outer adsorbed and reser-voired free oils at present,further indicating that most of the heavy oils are secondary in origin. Analyses of bacteria (microbes) in 7 oil samples indicate that anaerobic and hyperthermophilic Ar-chaeoglobus sp. are the dominant microbes relevant to oil biodegradation,which coincides with the shallow commercial gas reservoirs containing anaerobic bacteria derived gas in the Gaosheng and Leijia teotonic belts. The biodegradation most likely occurs at the water/oil interface,where the forma-tion water is essential for microbe removal and nutrient transportation. We think that biodegradation,water washing and oxidization are interrelated and are the main mechanisms for the formation of the heavy oils. Biodegradation was the predominant process with water washing being a prerequisite,and oxidization acting as a metabolic manifestation. This study provides unique approaches for further investigation of the formation mechanisms of heavy oils in general,and may provide some important insight for the exploration of shallow biogas in the area. | LI SuMei1,2,PANG XiongQi1,2,LIU KeYu3,GAO XianZhi1,2,LI XiaoGuang4,CHEN ZhenYan4 & LIU BaoHong41 State Key Laboratory of Petroleum Resource and Prospecting,China University of Petroleam,Beijing 102249,China 2 Basin and Reservoir Research Center,China University of Petroleum,Beijing 102249,China 3 CSIRO Petroleum,P.O. Box 1130,Bentley WA 6102,Australia 4 Liaohe Oilfield Co. Ltd,PetroChina,Panjin 124010,China | 2008 | Science China Earth Sciences2008，51，S2： | 2 |
| 8 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 2 |
| 9 | Epidemiology and control of hand,foot and mouth disease in Singapore,2001-2007 显示文摘 | Li WA Benjamin KW Kwai PC | 2009 | Ann Acad Med Singapore2009，38，： | 1 |
| 10 | Statin therapy and risk of dementia in the elderly: a community-based prospeetive cohort study显示文摘 | Li G Higdon R Kukull WA et L | 2004 | Neurology2004，63，9： | 1 |
| 11 | Expression of a novel alternative transcript of the novel retinal pigment epithelial cell gene NORPEG in human testes显示文摘瞄准:为了识别新奇网膜的颜料的一个新奇其他的抄本,上皮的房间基因(NORPEG ) 在人的睾丸表示了。方法:人的睾丸 cDNA 微数组被建立,有 cDNA 的 hybridized 从人的胎儿的睾丸,成年睾丸和人的精子探查。差别表示了克隆被定序并且分析。这些克隆之一是我们继续了由 RT-PCR 分析的 NORPEG 的一个短抄本。结果:NORPEG 的新奇短其他的抄本被孤立并且称为 sNORPEG。它是在长度的 3486 bp 并且包含了一个 2952-bp open 读物框架,编码 983 氨基酸的 110.4-kDa 蛋白质。氨基酸顺序分析证明 sNORPEG 蛋白质包含六次 ankyrin 重复和二个卷卷领域。它在它的顺序和主题与 NORPEG 和 ankycorbin 蛋白质分享高相同。爆炸人的染色体数据库局部性的 sNORPEG 到人的染色体 5p13.2-13.3。表示侧面证明 sNORPEG 在人的胎儿的睾丸,成年睾丸和精子被表示。而且, sNORPEG 被发现无所不在地在人的纸巾被表示。结论:sNORPEG 在睾丸的不同发展阶段被表示并且编码可以在人的睾丸开发和精子发生有角色的蛋白质。 | Wa Yuan Ying Zheng Ran Huo Li Lu Xiao-Yan Huang Lan-Lan Yin Jian-Min Li Zuo-Min Zhou Jia-Hao Sha | 2005 | Asian Journal of Andrology2005，7，3： | 1 |
| 12 | Simuhaneous quantification of five major biologically active ingredients of saffron by high - perform- ance liquid chromatography显示文摘 | Na Li Ge Lin Yiu - Wa Kwana | 1999 | J of Chromatogr A1999，849，： | 1 |
| 13 | Structure and evolution of the lipase superfamily显示文摘 | Hide WA Chan L Li WH | 1992 | J Lipid Res1992，33，2： | 1 |
| 14 | St r o k e i nChina:epidemiology, prevention, and managementstrategies显示文摘 | Li u M Wu B Wa n g WZ e t a l | 2007 | Lancet Neurol2007，6，： | 1 |
| 15 | Electronic confinement and coherence in patterned epitaxial grapheme 显示文摘 | Berger C Song Z Li X Wu X Naud C Mayou D LJ T Hass J Marchenkov AN Conrad EH First PN de Heer WA | 2006 | Science2006，312，： | 1 |
| 16 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng FRCSEd (Gen) Ka Lau Leung MD FRCS (Edin) Janet F. Y. Lee MD FRCSEd (Gen) Raymond Y. C. Yiu FRCSEd (Gen) Jimmy C. M. Li FRACS Anthony Y. B. Teoh MRCS (Edin) Wing Wa Leung MSc | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 17 | Laparoscopic-Assisted Versus Open Abdominoperineal Resection for Low Rectal Cancer: A Prospective Randomized Trial显示文摘 | Simon S. M. Ng Ka Lau Leung Janet F. Y. Lee Raymond Y. C. Yiu Jimmy C. M. Li Anthony Y. B. Teoh Wing Wa Leung | 2008 | Annals of Surgical Oncology2008，，9： | 1 |
| 18 | Dual role for nitric oxide in dynorphin spinal neurotoxicity显示文摘 | Hu WH Li F Qiang WA | 1999 | J Neurotrauma1999，16，1： | 1 |
| 19 | Characteristics of cancercell death after exposure to cytotoxic drugs in vitro显示文摘 | Bartier WA Ross CE | 1996 | Br J Cancer1996，73，1： | 1 |
| 20 | Learning and reconsolidation implicate different synaptic mechanisms显示文摘 | Li Y Meloni EG Carlezon WA Milad MR Jr | 2013 | Proc Natl Acad Sci USA2013，110，： | 1 |
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