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    题名 作者 年代 出处 被引量
1Hepatic abscess induced by foreign body:Case report and literature review显示文摘Hepatic abscess due to perforation of the gastrointestinal tract caused by ingested foreign bodies is uncommon. Pre-operative diagnosis is difficult as patients are often unaware of the foreign body ingestion and symptoms and imagiology are usually non-specific. The authors report a case of 62-year-old woman who was admitted with fever and abdominal pain. Further investigation revealed hepatic abscess, without resolution despite antibiotic therapy. A liver abscess resulting from perforation and intra-hepatic migration of a bone coming from the pilorum was diagnosed by surgery. The literature concerning foreign body-induced perforation of the gastrointestinal tract complicated by liver abscess is reviewed.Sofia A Santos Sara CF Alberto Elsa Cruz Eduardo Pires Tomás Figueira lia Coimbra José Estevez Mário Oliveira Luís Novais Joo R Deus 2007World Journal of Gastroenterology2007,13,9:10
2Results of R0 surgery with D2 lymphadenectomy for the treatment of localised gastric cancer显示文摘Díaz de Liao A Yárnoz C Artieda C 0,,03:1
3Tolerance analysis for combdrive actuator using DRIE fabrication显示文摘Li J Lia A O Zhang Q X 2006Sensors Actuators2006,125,02:1
4Horizontal sensory strabismus:characteristics and treatment results显示文摘Merino P Mateos C Gómez De Lia(o) P Franco G Nieva I Barreto A 0,,11:1
5Morbidity and mortality in gastrectomy with D2 lymphadenectomy in a specialised unit显示文摘Díaz de Liao A Yárnoz C Aguilar R 2008Cir Esp2008,83,1:1
6A proposed mechanism for nitrate and thiocyanate elution of strong-base ion exchange resins loaded with copper and gold cyanocomplexes显示文摘Adé lia M O Versiane A L Carlos A S 2008React Funct Polym2008,68,1:1
7Effect of pantethine on post - heparin lipolytic activity and lipid peroxidation in the myocardium显示文摘KUMEROVA A O SILOVA A A LIA U 1991Biulleten''Eksperimentalfioi Biologiii Meditsiny1991,111,1:1
8Life-cycle assessment ofbiodiesel production from microalgae显示文摘Lardon L Hélias A Sialve B Steyer J P Bernard O 0,,17:1
9Partitioning of model proteins in aqueous two-phase systems containing polyethylene glycol and ammonium carbamate显示文摘NAT(A)LIA LUIZA PENNA DALLORA JO(A)O GABRIEL DEGAM KLEM PEDRO DE ALC(A)NTARA PESSO(O)A FILHO 2007Biochemical Engineering Journal2007,34,1:1
10Partitioning of model proteins in aqueous two-phasesystems containing polyethylene glycol and ammonium carbamate显示文摘Natália Luiza Penna Dalloraa Jo?o Gabriel Degam Klemza and Pedro de Alc?ntara Pess?a Filho 2007Biochemical Engineering Journal2007,34,1:1
11Prognosis of acute tubular necrosis: an extended prospectively contrasted study显示文摘Lia O F Gallego A Pascual J 1993Nephron1993,63,1:1
12Emerging role of liquid biopsy in rat sarcoma virus mutated metastatic colorectal cancer:A case report显示文摘BACKGROUND In patients with metastatic colorectal cancer(mCRC),the treatment options are limited and have been proved to be affected by rat sarcoma virus(RAS)mutational status.In RAS wild-type(wt)patients,the combination of antiepidermal growth factor receptor(EGFR)monoclonal antibodies with chemotherapy(CT)is more effective than CT alone.On the other hand,RAS-mutated patients are not eligible for treatment with anti-EGFR antibodies.CASE SUMMARY Eleven patients with initially RAS-mutated mCRC were followed from diagnosis to May 2022.At the time of cell-free DNA determination,five patients had undergone one CT line,five patients had undergone two CT lines,and one patient had undergone three CT lines(all in combination with bevacizumab).At the second and third treatment lines[second line(2L),third line(3L)],patients with neo-RAS wt received a combination of CT and cetuximab.In neo-RAS wt patients treated with anti-EGFR,our findings indicated an increase in progression-free survival for both 2L and 3L(14.5 mo,P=0.119 and 3.9 mo,P=0.882,respectively).Regarding 2L overall survival,we registered a slight increase in neo-RAS wt patients treated with anti-EGFR(33.6 mo vs 32.4 mo,P=0.385).At data cut-off,two patients were still alive:A RAS-mutated patient undergoing 3L treatment and a neo-RAS wt patient who received 2L treatment with anti-EGFR(ongoing).CONCLUSION Our case series demonstrated that monitoring RAS mutations in mCRC by liquid biopsy may provide an additional treatment line for neo-RAS wt patients.João Gramaça Isabel Gomes Fernandes Carolina Trabulo Joana Gonçalves Rita Gameiro dos Santos Adriano Baptista Idília Pina 2024World Journal of Gastrointestinal Oncology2024,16,1:0
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