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您的检索式：作者名="Lian‑Hu Yu"
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| 1 | Preface to the special issue on advanced preparation of tungsten-related materials and their applications显示文摘Tungsten and related metals,including cobalt,molybdenum,vanadium,as well as their compounds,were an important group of materials to the sustainable development of our society.Since materials hold the key on various devices,much effort has been devoted to designing a large library of advanced tungsten-related metals and compounds to improve the devices performance,including fusion reactors and energy storage and conversion(ESC)devices. | Yu‑Xiang Hu Lian‑Zhou Wang | 2020 | Tungsten2020，2，4： | 0 |
| 2 | Tackling barriers to scale up human papillomavirus vaccination in China:progress and the way forward显示文摘The human papillomavirus(HPV)vaccine is the first vaccine developed specifically targeting the prevention of cervical cancer.For more than 15 years,China has expedited a series of efforts on research and development of the domestically manufactured HPV vaccines,producing local population-based evidence,promoting free HPV vaccination from pilots,and launching action plans to tackle barriers in the scale-up of HPV vaccination.To further roll out the HPV vaccination program in China,several challenges should be addressed to support the steps forward.The availability of more locally manufactured HPV vaccines,pricing negotiation and local evidence supporting the efficacy of one-dose schedule would greatly alleviate the continued supply and financial constraints in China.Meanwhile,more attention should be paid to girls living in low-resource areas and males to ensure equal access to the HPV vaccination.Furthermore,linkage to secondary prevention and further real-world monitoring and evaluation are warranted to inform effective cervical cancer prevention strategies in the post-vaccine era. | Xue‑Lian Zhao Shang‑Ying Hu Jia‑Wei Hu Hong‑Hao Wang Tian‑Meng Wen Yu‑Shu Feng You‑Lin Qiao Fang‑Hui Zhao Yong Zhang | 2023 | Infectious Diseases of Poverty2023，12，5： | 0 |
| 3 | Altered gut microbiota composition in children and their caregivers infected with the SARS‑CoV‑2 Omicron variant显示文摘Background Gut microbiota alterations have been implicated in the pathogenesis of coronavirus disease 2019(COVID-19).This study aimed to explore gut microbiota changes in a prospective cohort of COVID-19 children and their asymptomatic caregivers infected with the severe acute respiratory syndrome coronavirus type 2(SARS-CoV-2)Omicron variant.Methods A total of 186 participants,including 59 COVID-19 children,50 asymptomatic adult caregivers,52 healthy children(HC),and 25 healthy adults(HA),were recruited between 15 April and 31 May 2022.The gut microbiota composition was determined by 16S rRNA gene sequencing in fecal samples collected from the participants.Gut microbiota functional profling was performed by using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States(PICRUSt)software.Results The gut microbiota analysis of beta diversity revealed that the fecal microbial community of COVID-19 children remained far distantly related to HC.The relative abundances of the phyla Actinobacteria and Firmicutes were decreased,whereas Bacteroidetes,Proteobacteria,and Verrucomicrobiota were increased in COVID-19 children.Feces from COVID-19 children exhibited notably lower abundances of the genera Blautia,Bifdobacterium,Fusicatenibacter,Streptococcus,and Romboutsia and higher abundances of the genera Prevotella,Lachnoclostridium,Escherichia-Shigella,and Bacteroides than those from HC.The enterotype distributions of COVID-19 children were characterized by a high prevalence of enterotype Bacteroides.Similar changes in gut microbiota compositions were observed in asymptomatic caregivers.Furthermore,the microbial metabolic activities of KEGG(Kyoto Encyclopedia of Genes and Genomes)and COG(cluster of orthologous groups of proteins)pathways were perturbed in feces from subjects infected with the SARS-CoV-2 Omicron variant.Conclusion Our data reveal altered gut microbiota compositions in both COVID-19 children and their asymptomatic caregivers infected with the SARS-CoV-2 Omicron variant,which further implicates the critical role of gut microbiota in COVID-19 pathogenesis. | Yi‑Zhong Wang Jian‑Guo Zhou Yan‑Ming Lu Hui Hu Fang‑Fei Xiao Ting Ge Xing Wang Lu Zheng Lian‑Hu Yu Jun Le Hui Yu Guang‑Jun Yu Qiang Xia Ting Zhang Wen‑Hao Zhou | 2023 | World Journal of Pediatrics2023，19，5： | 0 |
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