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| 1 | Changed clinical aspects of primary liver cancer in China during the past 30 years显示文摘BACKGROUND: Primary liver cancer (PLC) is one of the most frequently seen tumors in China. Thirty years ago, patients with PLC were often detected at relatively late stage, with a palpable mass or marked clinical symptoms and poor prognosis. In the past 30 years, the diagnosis and treatment of PLC have been greatly improved with better prognosis. METHODS: In order to study the changes of PLC during the 30 years, the clinical data of 3250 patients with PLC from 10 medical institutions of China were collected, ana- lyzed , and compared with those of 3254 PLC patients be- fore the 30 years. RESULTS: In the 3250 patients aged 1-80 years, with an average age of 49.1 years, the male to female ratio (2.3:1) was lower than that before the 30 years. 73.5% of the 3250 patients sought medical advice within 3 months after the onset of the disease in contrast to 63.8% before the 30 years. Compared with those patients before the 30 years the symptoms and signs were alleviated generally. The HBsAg positive rate was 81.0%, but the HCV-Ab positive rate was 13.2%. The AFP level in 75% of patients was elevated, but in the remaining 25% was normal. 1912 patients (58.8%) were confirmed pathologically. Among them 1755 patients (91.8%) had hepatocellular carcinoma. The overall resec- tion rate was 46.3%. Those who had early, middle, late stage carcinoma accounted for 29.9%, 51.5%, and 18.6%respectively in contrast to 0.4%, 47.0%, and 52.6% repor- ted before the 30 years. The 1-, 3-, 5-year survival rates of the patients were 66.1%, 39.7%, and 32.5% respectively, whereas 93.5%, 70.1%, and 59.1% for the early stage pa- tients, and 65.3%, 30.5%, and 23.5% for the middle stage patients. The half and 1-year survival rates of the late stage patients were 52.5%, and 14.7%, respectively. CONCLUSION: Comparison with the clinical data before and after the 30 years show that PLC can be diagnosed ear- ly. More PLC patients tend to undergo resection while re- ceiving a better conservative treatment, which ensures a prognosis. | Bing-Hui Yang, Jing-Lin Xia, Li-Wen Huang, Zhao-You Tang, Ming-Shan Chen, Jin-Qing Li, An-Min Liang, Qin-Guo Mo, Hui-Shan Lu, Chao-Liu Dai, Lu-Nan Yan, Zhi-Jian Yu, Rong-Sheng Rao, Le-Qun Li, Zhi-Xiong Su, Zhuang-Wei Fang Shanghai, China Liver Cancer Institute & Zhongshan Hospital, Fudan University, Shanghai 200032, China Tumor Hospital, Zhongshan University, Guangzhou 510000, China Tumor Hospital, Guangxi Medical Universi- ty, Nanning 530000, China Xiehe Hospital, Fujian Medical University, Fuzhou 350000, China Second Hos- pital, Chinese Medical University, Shenyang 110000, China Huaxi Hospital, Sichuan University, Chengdu 610041, China Hospital Affiliated to Nantong Medical University, Nantong 226000 , China Second Hospital, Jiangxi Medical University, Nanchang 330000 , China First Hospital Affiliated to Guangxi Medical University, Nanning 530000 , China People’s Hospital of Hainan Province, Haikou 570000, China | 2004 | Hepatobiliary & Pancreatic Diseases International2004，3，2： | 20 |
| 2 | Emergency assessment of seismic landslide susceptibility: a case study of the 2008 Wenchuan earthquake affected area显示文摘The 8.0 Mw Wenchuan earthquake triggered widespread and large scale landslides in mountainous regions.An approach was used to map and assess landslide susceptibility in a given area.A numerical rating system was applied to fi ve factors that contribute to slope instability.Factors such as lithology,topography,streams and faults have an important influence as event-controlling factors for landslide susceptibility assessment.A f inal map is provided to show areas of low,medium,and high landslide susceptibility.Areas identifi ed as having high landslide susceptibility were located in the central,northeastern,and far south regions of the study area.The assessment results will help decision makers to select safe sites for emergency placement of refuges and plan for future reconstruction.The maps may also be used as a basis for landslide risk management in the study area. | Tang Chuan,Zhu Jing and Liang Jingtao State Key Laboratory of Geo-Hazard Prevention,Chengdu University of Technology,Chengdu 610059,China Professor Associate Professor Graduate Student | 2009 | Earthquake Engineering and Engineering Vibration2009，8，2： | 16 |
| 3 | Effect of caffeic acid phenethyl ester on proliferation and apoptosis of hepatic stellate cells in vitro显示文摘AIM: To investigate the role of nuclear factor-κB (NF-κB)inhibitor caffeic acid phenethy1 ester (CAPE) in the proliferation, collagen synthesis and apoptosis of hepatic stellate cells (HSCs) of rats.
METHODS: The HSCs from rats were isolated and cultured in Dulbecco's Modified Eagle's Medium (DMEM) and treated with CAPE. The proliferation and collagen synthesis of HSCs were determined by 3H-TdR and 3H-proline incorporation respectively, and the expression of type Ⅰ, Ⅲ procollagen genes was further explored byin situ hybridization. Apoptosis cell indices (AIs) were examined using terminal deoxynucleotidyl transferase- mediated DIG-dUTP nick end labeling (TUNEL).
RESULTS: Tn activated HSC in culture, CAPE significantly inhibited 3H-TdR and 3H-proline incorporation by HSCs at concentrations of 5 μmol/L and 10 μmol/L respectively. CAPE also reduced the type I procollagen gene expression (P<0.05)at higher concentration. Apoptosis of HSC was induced by CAPE and the AIs were time-and dose-dependently increased from 2.82+0.73 % to 7.66±1.25 % at 12 h (P<0.01) and from 3.15±0.88 % to 10.6L±2.88 % at 24 h (P<0.01).
CONCLUSION: CAPE inhibits proliferation and collagen synthesis of HSC at lower concentration and induces HSC apoptosis at higher concentration. | Wen-Xing Zhao Jing Zhao Chong-Li Liang Bing Zhao Rong-Qing Pang Xing-Hua Pan Medical Laboratory of Kunming General Hospital,Chengdu Command,Kunming 650032,Yunnan Province,China | 2003 | World Journal of Gastroenterology2003，9，6： | 12 |
| 4 | Ni supported on activated carbon as catalyst for flue gas desulfurization显示文摘A series of Ni supported on activated carbon are prepared by excessive impregnation and the desulfurization activity is investigated. It has been shown that the activated carbon-supported Ni is an efficient solid catalyst for flue gas desulfurization. The activated carbon treated by HNO3 exhibits high desulfurization activity, and different amounts of loaded-Ni on activated carbon significantly influence the desulfurization activity. The catalysts are studied by X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The results of XRD and XPS indicate that the activated carbon treated by HNO3 can increase oxygen-containing functional groups. Ni on activated carbon after calcination at 800 °C shows major Ni phase and minor NiO phase, and with increasing Ni content on activated carbon, Ni phase increases and affects the desulfurization activity of the catalyst, which proves that Ni is the main active phase. | CHU YingHao1,2, GUO JiaXiu1,2, LIANG Juan1,2, ZHANG QiangBo1 & YIN HuaQiang1,2 1Department of Environmental Science and Engineering, Sichuan University, Chengdu 610065, China 2National Engineering Technology Research Center for Flue Gas Desulfurization, Sichuan University, Chengdu 610065, China | 2010 | Science China Chemistry2010，53，4： | 11 |
| 5 | CONTINUOUS L-DOMAINS显示文摘Two characterization theorems of continuous L-domain are given. Then a problem raisedby J. D. Lawson and M. Mislove is solved. | LIANG JIHUA LIU YINGMING(Institute of Mathematics, Sichuan University, Chengdu 610064, China.)(Project supported by the National Natural Science Foundation of China.) | 1996 | Chinese Annals of Mathematics,Series B1996，17，3： | 8 |
| 6 | High-performance aqueous symmetric sodium-ion battery using NASICON-structured Na2VTi(PO4)3显示文摘 | Hongbo wang Tianran Zhang Chao Chen Min Ling Zhan Lin Shanqing Zhang Feng Pan Chengdu Liang | 2018 | Nano Research2018，11，1： | 6 |
| 7 | Synthesis and Crystal Structure of Binuclear Oxomolybdenum(VI) Complex with Both o-Mercaptophenolate显示文摘The complex (Bu4N) 2 [Mo2O5 (mp)2] was synthesized by the reactionof (Bu4N)2[Mo8O26] with H2mp (H2mp=o-mercaptophenol) in methanol. The molecular formula is C44H80Mo2N2O7S2, M.=1005.10. The complex is crystallized in monoclinic, space group P21/n with unit cell parameters, a = 17. 829 (2) A, b= 13. 759 (2 )A,c= 21. 974(2) A, g=105. 386(8)°, V= 5197. 4(1) , Dc= 1. 285 g/cm3, Z=4,λ(MoKa) =0. 71073 , μ=0. 607 mm-1,F(000) = 2120, final R=0.0348 and wR=0. 0741 for 4912 independent observed reflections (FM>4σ(Fo) ). Two MoO5S units inthe complex molecule exhibits the con facial distorted bioctahedral geometry and possesses an approximate C2 symmetry. | WANG Xiu-Jian CHEN Zhen-Feng LIANG Hong(Department of Chemistry and Chemical Industry,Guangxi Normal University, Guilin, 541004)YU Kai-Bei(Chengdu Center of Analysis and Measurememt,the Chinese Academy of Scicnces, Chengdu 610041) | 1997 | Chinese Journal of Structural Chemistry1997，16，5： | 4 |
| 8 | Influence of CaZrO_3 on dielectric properties and microstructures of BaTiO_3-based X8R ceramics显示文摘The influences of CaZrO3 on the dielectric properties and microstructures of BaTiO3 (BT)-based ceramics have been investigated. The experiment results showed that the dielectric constant at room temperature increased with the addition of CaZrO3 in the range of 0―3.0 mol%, which could be explained by the growth of BT grains. XRD analysis revealed that the tetragonality declined as CaZrO3 concentration in-creased. XRD patterns of BT ceramics with different amounts of CaZrO3 doping were analyzed by a recently developed procedure-materials analysis using diffrac-tion (MAUD), which was based on the Rietveld method combined with Fourier analysis. The results depicted that the high temperature peak of tempera-ture-capacitance characteristics (TCC) was largely dependent on the micro-strain of samples. Furthermore, more CaZrO3 doping resulted in lower porosity and higher density. It was revealed that proper usage of CaZrO3 could improve the di-electric properties significantly, which was benefit to develop X8R multi-layer ce-ramic capacitors. | TANG Bin, ZHANG ShuRen, YUAN Ying, ZHOU XiaoHua & LIANG YiShuai State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu 610054, China | 2008 | Science China(Technological Sciences)2008，51，9： | 2 |
| 9 | Ladinian radiolarian fauna, siliceous rock from the Xianshuihe Belt, West Sichuan and their tectonic significance显示文摘Ladinian radiolarian fauna, including Muelleritortis, Baumgartneria, Oertlispongus,Paroertlispongus, Pseudoertlispongus, etc., was discovered from the siliceous rock of the Runiange Formation in the Xianshuihe belt, West Sichuan Province. Geochemical test on five samples from the siliceous rock indicates that SiO2 content varies in 71.16%-90.06% and Si/Al ratio, in 49-71, which shows that the siliceous rock contains more terrigenous mud sediments.The siliceous rock is characterized by the large ratios of Al203/(Al203+Fe203) (0.63-0.81) and TiN (>26), the low ratio of V/Y (<2.8), and low vanadium content (<23 μg/g), which are similar to the geochemical characteristics of continental margin siliceous rock. The Ce/Ce* ratios of the four samples vary in 1.02-1.47 and the LaN/CeN ratio, in 0.75-1.07, which imply that the siliceous rock was deposited in the continental margin basin. But only one sample is similar to the oceanic siliceous rock in REE. Turbidite-siliceous rock bearing radiolarian-basalt assemblage and the geochemical characteristics of the siliceous rock indicate that the Xianshuihe belt is in the strong rift stage in the Ladinian age. | LIANG Bin, FENG Qinglai, WANG Quanwei, GUO Jianqiu, ZHONG Changhong & LI Zhenjiang Faculty of Earth Science, China University of Geosciences, Wuhan 430074, China Sichuan Geological Survey, Chengdu 610000, China | 2005 | Science China Earth Sciences2005，48，1： | 2 |
| 10 | Effect of Konjac Food on Blood Glucose Level in Patients with Diabetes显示文摘Seventy-two type II diabetic subjects were given Konjac food for 65 days. The data analyzed by multiple F test indicate that the fasting blood glucose (FBG) and the 2-h postprandial blood glucose (PBG) on the 30th and the 65th days after the food was ingested were significantly reduced (P = 0.001, P < 0.001, respectively), as was the glycosylated hemoglobin level at the end of the trial (P < 0.05). The final FBG and PBG of the subjects with initial FBG-O >200 mg% decreased on the average by 51.8 and 84.6 mg%. respectively; those with FBG-0 150-200 mg% decreased by 24.1 and 68.7 mg%; and those with FBG-O < 150 mg% decreased by 4.8 and 21.4 mg%. No significant changes in blood lipid indexes were observed, except that the triglycer-ide values of subjects with hypertriglyceridemia (>200 mg%) significantly decreased by 118.7 mg%. It was concluded that Konjac food is very useful in the prevention and treatment of hyperglycemia. (C)1990 Academic Press. Inc. | HUANG CHENG-YU,~*ZHANG MAO-YU,~*PENG SHU-SHENG,~*HONG JUN-RONG,~*WANG XU,~*JIANG HUIJUN,~*ZHANG FULIN,~*BAI YUNXIANG,~*LIANG JINZHONG,Yu YERONG,LUO ZHAOTIAN,ZHANG XIANGXUN,AND ZHOU ZANCHENG~*School of Public Health, West China University of Medical Sciences (WCUMS). Chengdu, China Department of Endocrinology, First University Hospital of WCUMS, Chengdu, China and Staff Hospital of 107 Post Office Box, Chengdu, China | 1990 | Biomedical and Environmental Sciences1990，3，2： | 2 |
| 11 | ON THE SPACES OF THE MAXIMAL POINTS显示文摘For a continuous domain D, some characterization that the convex powerdomain CD is adomain hull of Max(CD) is given in terms of compact subsets of D. And in this case, it isproved that the set of the maximal points Max(CD) of CD with the relative Scott topology ishomeomorphic to the set of all Scott compact subsets of Max(D) with the topology induced bythe Hausdorff metric derived from a metric on Max(D) when Max(D) is metrizable. | LIANG JIHUA LIU YINGMING Institute of Mathematics, Sichuan University, Chengdu 610064, China. Institute of Mathematics, Sichuan University, Chengdu 610064, China. | 2003 | Chinese Annals of Mathematics,Series B2003，24，3： | 2 |
| 12 | Synthesis of a large-scale highly ordered porous carbon film by self-assembly of block copolymers 显示文摘 | Liang Chengdu Hong Kunlun Guiochon G A | 2004 | Angewandte Chemie International Edition2004，43，43： | 1 |
| 13 | MORE FACILE SYNTHESES TO THE SEX PHEROMONE COMPONENTS OF THE WINTER MOTH(OPEROPHTERABRUMATAL.(LEPIDOPTERA:GEOMETRIDAE):(3Z,6Z,9Z)-3,6,9-NONADECATRIENE,(6Z,9Z)-6,9-NONADECADIENE显示文摘MOREFACILESYNTHESESTOTHESEXPHEROMONECOMPONENTSOFTHEWINTERMOTH(OPEROPHTERABRUMATAL.(LEPIDOPTERA:GEOMETRIDAE):(3Z,6Z,9Z)-3,6,9-... | Bao Ming Xu Liang Fn HUANG Shu Xiang SHAN and Xue You ZHU(Departmnt of Biotechnoleqy, Sichuan University, Chengdu 610064)(Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,345 Linqling Lu, Shanghai Z00032)(Present address:Chemical Eng | 1994 | Chinese Chemical Letters1994，5，1： | 1 |
| 14 | Development of a new atropine sulfate bulk acoustic wave sensor based on a molecularly imprinted electrosynthesized copolymer of aniline with o-phenylenediamine显示文摘 | Peng Hui Liang Chengdu Zhou Anhong | 2000 | Anal Chim Acta2000，423，2： | 1 |
| 15 | Development of a new atropine sulfate bulk acoustic wave sensor based on a molecularly imprinted electrosynthesized copolymer of aniline with o-phenylenediamine 显示文摘 | PENG Hui LIANG Chengdu ZHOU Anhong | 2000 | Anal Chim Acta2000，423，2： | 1 |
| 16 | Hierarchically structured sulfur/carbon nanocomposite material for high-energy lithium battery显示文摘 | Liang Chengdu Dudney Nancy J Howe Jane Y | 2009 | Chemistry of Materials2009，21，19： | 1 |
| 17 | Selective Adsorption and Electrocatalysis of Polysulfides through Hexatomic Nickel Clusters Embedded in N-Doped Graphene toward High-Performance Li-S Batteries显示文摘The shuttle effect hinders the practical application of lithium-sulfur(Li-S)batteries due to the poor affinity between a substrate and Li polysulfides(LiPSs)and the sluggish transition of soluble LiPSs to insoluble Li2S or elemental S.Here,we report that Ni hexatomic clusters embedded in a nitrogen-doped three-dimensional(3D)graphene framework(Ni-N/G)possess stronger interaction with soluble polysulfides than that with insoluble polysulfides.The synthetic electrocatalyst deployed in the sulfur cathode plays a multifunctional role:(i)selectively adsorbing the polysulfides dissolved in the electrolyte,(ii)expediting the sluggish liquid-solid phase transformations at the active sites as electrocatalysts,and(iii)accelerating the kinetics of the electrochemical reaction of multielectron sulfur,thereby inhibiting the dissolution of LiPSs.The constructed S@Ni-N/G cathode delivers an areal capacity of 9.43mAhcm^(-2) at 0.1 C at S loading of 6.8 mg cm^(-2),and it exhibits a gravimetric capacity of 1104mAhg^(-1) with a capacity fading rate of 0.045%per cycle over 50 cycles at 0.2 C at S loading of 2.0 mg cm^(-2).This work opens a rational approach to achieve the selective adsorption and expediting of polysulfide transition for the performance enhancement of Li-S batteries. | Jiapeng Ji Ying Sha Zeheng Li Xuehui Gao Teng Zhang Shiyu Zhou Tong Qiu Shaodong Zhou Liang Zhang Min Ling Yanglong Hou Chengdu Liang | 2020 | Research2020，，1： | 1 |
| 18 | Mesoporous Carbon Materials:Synthesis and Modification显示文摘 | Liang Chengdu Li Zuojiang Dai Sheng | 2008 | Angewandte Chemie International Edition2008，47，20： | 1 |
| 19 | Synthesis of a large-scale highly ordered porous carbon film by self-assembly of block copolymers 显示文摘 | Liang Chengdu Hong Kunlun Georges A Guiochon | 2004 | Angew Chem Int Ed Eng12004，43，43： | 1 |
| 20 | Hierarchically Structured Sulfur/Carbon NanocompositeMaterial for High-Energy Lithium Battery显示文摘 | Liang Chengdu Nancy J D Jane Y H | 2009 | Chemistry of Materials2009，21，： | 1 |
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