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| 1 | Relationship between Th17 immune response and cancer显示文摘Cancer is the second leading cause of death worldwide and epidemiological projections predict growing cancer mortality rates in the next decades.Cancer has a close relationship with the immune system and,although Th17 cells are known to play roles in the immune response against microorganisms and in autoimmunity,studies have emphasized their roles in cancer pathogenesis.The Th17 immune response profile is involved in several types of cancer including urogenital,respiratory,gastrointestinal,and skin cancers.This type of immune response exerts pro and antitumor functions through several mechanisms,depending on the context of each tumor,including the protumor angiogenesis and exhaustion of T cells and the antitumor recruitment of T cells and neutrophils to the tumor microenvironment.Among other factors,the paradoxical behavior of Th17 cells in this setting has been attributed to its plasticity potential,which makes possible their conversion into other types of T cells such as Th17/Treg and Th17/Th1 cells.Interleukin(IL)-17 stands out among Th17-related cytokines since it modulates pathways and interacts with other cell profiles in the tumor microenvironment,which allow Th17 cells to prevail in tumors.Moreover,the IL-17 is able to mediate pro and antitumor processes that influence the development and progression of various cancers,being associated with variable clinical outcomes.The understanding of the relationship between the Th17 immune response and cancer as well as the singularities of carcinogenic processes in each type of tumor is crucial for the identification of new therapeutic targets. | Hanna Santos Marques Breno Bittencourt de Brito Filipe Antônio França da Silva Maria Luísa Cordeiro Santos Júlio César Braga de Souza Thiago Macêdo Lopes Correia Luana Weber Lopes Nayara Silva de Macêdo Neres Rafael Santos Dantas Miranda Dórea Anna Carolina Saúde Dantas Lorena Lôbo Brito Morbeck Iasmin Souza Lima Amanda Alves de Almeida Maiara Raulina de Jesus Dias Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，10： | 5 |
| 2 | Mood swings in patients with Crohn's disease: incidence and associat ed factors显示文摘 | Lima F D Ribeiro T C Chebli L A | 2012 | Rev Assoc Med Bras2012，58，4： | 1 |
| 3 | Magnitude and time course of microvascular obstruction and tissue injury after acute myocardial infarction显示文摘 | Rochitte C E Lima J A Bluemke D A | 1998 | Circulation1998，98，10： | 1 |
| 4 | A Comprehensive Strategy to Boost the Quantum Yield of Luminescence of Europium Complexes 显示文摘 | Lima N B D Gonqalves S M C Jtnior S A | 2013 | Sci Rep2013，3，： | 1 |
| 5 | Neurohumoral features of myocardial stunning due to sudden emotional stress显示文摘 | WITTSTEIN I S THIEMANN D R LIMA J A C | 2005 | N Engl J Med2005，352，： | 1 |
| 6 | Magnitude and time course of microvascular obstruction and tissue injury after acute myocardial infarction显示文摘 | Rochitte C E Lima J A Bluemke D A | 1998 | Circulation1998，98，10： | 1 |
| 7 | Knowledge about HPV and screening of cervical cancer among women from the metropolitan region of natal, brazil显示文摘 | Lima E G de Lima D B Miranda C A | 2013 | ISRN Obstet Gynecoh2013，2013，93： | 1 |
| 8 | Physical Characterization and Electrochemical Activity of Bimetallic Platinum- Silver Particles for Oxygen Reduction in Alkaline Electrolyte 显示文摘 | Lima F H B Sanches C D Ticianelli E A | 2005 | J Electrochem Soc2005，152，7： | 1 |
| 9 | lntestinal and pancreas enzyme activity of broilers exposed to thermal stress 显示文摘 | Routman K S l Yoshida L I Frizzas de Lima A C I et d | 2003 | Revista Brasileira de Ci-ncia Avlcola2003，5，1： | 1 |
| 10 | Neurohumoral features of myocardial stunning due to sudden emotional stress显示文摘 | WITTSTEIN I S THIEMANN D R LIMA J A C | 2005 | N Engl J Med2005，352，： | 1 |
| 11 | Imposex induction is mediated through the retinoid X receptor signalling pathway in the neogastropod nucella lapillus显示文摘 | CASTRO L F C LIMA D MACHADO A | 2007 | Aquatic Toxicology2007，85，1： | 1 |
| 12 | Neurohumoral features of myocardial stunning due to sudden emotional stress显示文摘 | WITTSTEIN I S THIEMANN D R LIMA J A C | 2005 | N Engl J Ivied2005，352，： | 1 |
| 13 | Biochar: A Synthesis of Its Agronomic Impact beyond Carbon Sequestration显示文摘 | Spokas Kurt A Cantrell Keri B M Novak Jeffrey Archer David W Ippolito James A Collins Harold P Boateng Akwasi A Lima Isabel M Lamb Marshall C McAloon Andrew J Lentz Rodrick D Nichols Kristine A | 2012 | Journal of Environmental Quality2012，，4： | 1 |
| 14 | Heart rate monitoring in soccer:interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bara Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength Cond Res2012，26，10： | 1 |
| 15 | Pine oleoresin: tapping green chemicals, biofuels, fnw| protection, and carbon sequestra lion from multipurpose trees显示文摘 | Rodrigues K C D S Lima J C Fett A G | 2013 | Food and Energy Seeurily2013，1，2： | 1 |
| 16 | Heart rate monitoring in soccer: interest and limits during competitive match play and training, practical applica- tion显示文摘 | Alexandre D da Silva C D Hill-Haas S Wong del P Natali A J De Lima J R Bars Filho M G Matins J J Garcia E S Karim C | 2012 | J Strength C ond Res2012，26，10： | 1 |
| 17 | Bmeystatin,a cysteine proteinase inhibitor characterized from the tick Boophilus microplus显示文摘 | LIMA C A SASAKI S D TANAKA A S | 2006 | Biochemical and Biophysical Research Communications2006，347，1： | 1 |
| 18 | Synthesis, doc- king and in vitro activity of thiosemicarbazones, aminoacyl- thiosemi-carbazides and acyl-thiazolidones against Trypano- soma cruzi显示文摘 | Leite A C de Lima R S Moreira D R | 2006 | Bioorg Med Chem Lett2006，14，11： | 1 |
| 19 | Synthesis of alumina powders by the glycine-nitrate combustion process 显示文摘 | Toniolo J C Lima M D Takimi A S | 2005 | Materials Research Bulletin2005，40，： | 1 |
| 20 | Comparative analysis of coherent light action (laser) versus non-coherent light (light-emitting diode) for tissue repair in diabetic rats显示文摘 | AgnolMAD Nicolau R A Lima C J D | 2009 | Lasers in Medical Science2009，24，6： | 1 |
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