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87篇 您的检索式:作者名="Lima RA"
    题名 作者 年代 出处 被引量
1Innate and adaptive immune responses toward nanomedicines显示文摘Since the commercialization of the frst liposomes used for drug delivery,Doxil/Caelyx® and Myocet®,tremendous progress has been made in understanding interactions between nanomedicines and biological systems.Fundamental work at the interface of engineering and medicine has allowed nanomedicines to deliver therapeutic small molecules and nucleic acids more effciently.While nanomedicines are used in oncology for immunotherapy or to deliver combinations of cytotoxics,the clinical successes of gene silencing approaches like patisiran lipid complexes(Onpattro®)have paved the way for a variety of therapies beyond cancer.In parallel,the global severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has highlighted the potential of mR NA vaccines to develop immunization strategies at unprecedented speed.To rationally design therapeutic and vaccines,chemists,materials scientists,and drug delivery experts need to better understand how nanotechnologies interact with the immune system.This review presents a comprehensive overview of the innate and adaptative immune systems and emphasizes the intricate mechanisms through which nanomedicines interact with these biological functions.Iara Maíra de Oliveira Viana Sabrina Roussel Joan Defrêne Eliana Martins Lima Frédéric Barabé Nicolas Bertrand 2021Acta Pharmaceutica Sinica B2021,11,4:5
2Choices on contraceptive methods in post-abortion family planning clinic in the northeast Brazil显示文摘Ferreira AL Souza AI Lima RA 2010Reprod Health2010,7,:1
3Prognostic factors and outcome for nasopharyngeal carcinoma 显示文摘Farias TP Dias FL Lima RA 2005Arch Otolaryngol Head Neck Surg2005,129,:1
4Flavonoids and isoflavonoids from Zollernia paraensis显示文摘Ferrari F Botta B de Lima RA 1983Phytochemistry1983,22,7:1
5Involvement and fragmentation:A study of parental care of hospitalized children in Brazil显示文摘De Lima RA Rocha SM Scochi CG 2001Pediatr Nurs2001,27,56:1
6Geissospermum vellosii stembark:anticholinesterase activity and improvement of scopolamine-induced memory deficits显示文摘Lima JA Costa RS Epifanio RA 2009Pharmacol Biochem Behav2009,92,3:1
7Supraomohyoid neck dissection in the treatment of T1/T2 squamous ceU carcinoma of oral cavity显示文摘Kligerman J Lima RA Soares JR 1994Am J Surg1994,168,5:1
8Results and complications of CT-guided transthoracic fineneedle aspiration biopsy of pulmonary lesions显示文摘Lima CD Nunes RA Saito EH 2011J Bras Pneumol2011,37,2:1
9Results and complica- tions of CT-guided transthoracic fine-needle aspiration biopsy of pulmonary lesions显示文摘De Lima CD Nunes RA Saito EH Jornal Brasi Pneumol0,37,2:1
10Supraomohyoid neck dissection in the treatment of T1/T2 squamous cell carcinoma of oral cavity 显示文摘Kligerman J Lima RA Soares JR 1994Am J Surg1994,168,5:1
11Prognostic factors and outcome for nasopharyngeal carcinoma显示文摘Farias TP Dias FL Lima RA 20032003,,:1
12Relevance of skip metastases for squamous cell carcinoma of the oral tongue and the floor of the mouth显示文摘Dias FL Lima RA Kligerman J 2006Otolaryngol Head Neck Surg2006,134,3:1
13Therapeutic options in advanced laryngeal cancer: an overview 显示文摘Dias FL Lima RA Kligerman J et at 2005ORL J Otorhinolaryngol Relat Spec2005,67,6:1
14Supraomohyoid neck dissection in the treatment of T1/T2 squamous cell carcinoma of the oral cavity显示文摘 Lima RA 1994Am J Surg1994,168,2:1
15Relevance of skip metastasesforsquamous cell carcinoma of the oral tongue and the floor of the mouth显示文摘Dias FL Lima RA Kligerman J 2006Otolaiyngol Head Neck Surg2006,134,46:1
16Prognostie factors and outcome for nasophatyngeal carcinoma显示文摘 Dias FL Lima RA 2003Arch O to laryngol Head Neck Surg2003,129,7:1
17Cryptosporidiosis: epidemiology and impact显示文摘Guerrant RL Dillingham RA Lima AA 2002Microbes and Infection2002,10,4:1
18Prognostic factors and outcome for nasopharyngeal carcinoma显示文摘Farias TP Dias FL Lima RA 2003Arch Otolaryngol Head Neck Surg2003,129,7:1
19Prognostic factors and out?come for nasopharyngeal carcinoma显示文摘Farias TP Dias FL Lima RA 2003Arch Dtolalyngol Head Neek Surg2003,129,7:1
20The prognostic value of cyclin D1 in renal cell carcinoma显示文摘Lima MS Pereira RA Costa RS 2014Int Urol Nephrol2014,46,5:1
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