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| 1 | 3D Positional and Quantitative Prediction of the Xiaoqinling Gold Ore Belt in Tongguan, Shaanxi, China显示文摘Quantitative prediction of deep orebody based on 3D visualization technology is of great significance in mineral exploration. Based on the 2D traditional quantitative predicting method, the geoanomaly theory and the mineral exploration model idea, we constructed 3D models of the topography, strata, structure, magmatite and prospecting engineering of the study area using the commercial 3D modeling software Micromine, delineated eight prospective areas and estimated the gold resources amount with methods of Abundance Estimation and Volume Estimation. Then, we compared and counted the known ore blocks and the predicted blocks, which quantitatively explains this prediction's validity. The results show that Xiaoqinling gold belt in Tongguan has convincing potential for gold development and utilization and the prediction method based on 3D visualization technology proves to be effective. | CHEN Jianping SHI Rui CHEN Zhenping WANG Limei SUN Yan | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 14 |
| 2 | Phylogenetic diversity and specificity of bacteria associated with Microcystis aeruginosa and other cyanobacteria显示文摘Interactions between bacteria and cyanobacteria have been suggested to have a potential to influence harmful algal bloom dynamics; however, little information on these interactions has been reported. In this study, the bacterial communities associated with five strains of Microcystis aeruginosa, three species of other Microcystis spp., and four representative species of non-Microcystis cyanobacteria were compared. Bacterial 16S rDNA fragments were amplified and separated by denaturing gradient gel electrophoresis (DGGE) followed by DNA sequence analysis. The similarities among bacterial communities associated with these cyanobacteria were compared to the digitized DGGE profiles using the cluster analyses. The bacterial community structure of all cyanobacterial cultures differed. Cluster analysis showed that the similarity values among M. aeruginosa cultures were higher than those of other cyanobacterial cultures. Sequence analysis of DGGE fragments indicated the presence of bacteria including, Alphaproteobacteria, Betaproteobacteria, Gammaproteobacteria, Bacteroidetes and Actinobacteria in the cyanobacterial cultures. Members of the Sphingomonadales were the prevalent group among the Microcystis-associated bacteria. The results provided further evidence for species-specific associations between cyanoabcteria and heterotrophic bacteria, which are useful for understanding interactions between Microcystis and their associated bacteria. | SHI Limei CAI Yuanfeng YANG Hualin XING Peng LI Pengfu KONG Lingdong KONG Fanxiang | 2009 | Journal of Environmental Sciences2009，21，11： | 11 |
| 3 | Spatial heterogeneity of cyanobacterial communities and genetic variation of Microcystis populations within large,shallow eutrophic lakes(Lake Taihu and Lake Chaohu,China)显示文摘Cyanobacteria,specifically Microcystis,usually form massive blooms in eutrophic freshwater lakes.Cyanobacterial samples were collected from eight sites of both Lake Taihu and Lake Chaohu in late summer to determine the diversity and distribution pattern of cyanobacteria and Microcystis in large,shallow,entropic lakes with significant spatial heterogeneity and long-term Microcystis bloom.Molecular methods based on denaturing gradient gel electrophoresis and clone library analysis were used.A similar heterogeneous distribution pattern of cyanobacteria in both lakes was observed.Most parts of these two lakes with high trophic level were dominated by Microcystis.However,in the regions with low trophic levels as well as low concentrations of chlorophyll a,Synechococcus occupied a considerable percentage.Different morphospecies and genotypes dominated the bloom-forming Microcystis populations in these two lakes.Microcystis viridis and Microcystis novacekii were dominant in Lake Chaohu,whereas Microcystis flos-aquae was dominant in Lake Taihu.Only 2 of the13 Microcystis operational taxonomic units were shared between these two lakes.Analysis of molecular variance based on 16S to 23S internal transcribed spacer sequences indicated the significant genetic differentiation of Microcystis between these two lakes(F st = 0.19,p < 0.001).However,only 19.46% of the genetic variability was explained by the population variation between lakes,whereas most(80.54%) of the genetic variability occurred within the lakes.Phylogenetic analysis revealed no phylogeographic structure of Microcystis population in these two lakes,as illustrated by their cosmopolitan nature.Our results revealed that spatial heterogeneity within lakes has more impact on the cyanobacterial diversity than geographical isolation in a local scale. | Yuanfeng Cai Fanxiang Kong Limei Shi Yang Yu | 2012 | Journal of Environmental Sciences2012，24，10： | 5 |
| 4 | Allergic diseases, immunoglobulin E, and autoimmune pancreatitis: a retrospective study of 22 patients显示文摘 | Guo Limei Huang Yonghui Wang Tianli Shi Xueying Chang Hong Yao Wei Huang Xuebiao | 2014 | Chinese Medical Journal2014，，23： | 5 |
| 5 | Busuishengxue ranules mediate their effects upon non-severe aplastic anemia via mitogen-activated protein kinase/extracellular signal-regulated kinase pathway显示文摘OBJECTIVE:To observe the clinical efficacy of Busuishengxue granules on non-severe aplastic anemia(NSAA)and investigate its effect on the mitogen-activated protein kinase/extracellular signal-regulated kinase(MAPK/ERK)pathway.METHODS:Sixty NSAA patients were divided equally into two groups.Subjects in the experimental group were treated with Busuishengxue granules,and the control group with Zaizaoshengxue tablets.The treatment course was 6 months and cu-rative efficacy was compared between the two groups as well as with 10 healthy individuals.Flow cytometry(FCM)was used to detect the intracellular concentration of Ca2+([Ca2+]i).Western blotting was employed to detect the expression of enzymes in the MAPK/ERK pathway.RESULTS:The efficacy of Busuishengxue granules was significantly better than that of Zaizaoshengxue tablets(P<0.05).Before treatment,expression of JNK,phospho-ERK 1/2 and p-JNK was higher,and[Ca2+]i higher,than that of the control group(P<0.05).After treatment with Busuishengxue granules,expression of all enzymes related to signal transduction pathways in the blood cells of NSSA patients were altered to different degrees.CONCLUSION:Busuishengxue granules had a better effect with regard to improving symptom scores,increasing the number of blood leukocytes,and increasing hemoglobin levels than Zaizaoshengxue tablets,and they differed slightly in terms of increasing the number of platelets. | Jinhuan Wang Feng Sun Weizheng Sun Yanli Yong Haitao Shi Sijia Liu Limei Liu | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 3 |
| 6 | Mn atomic layers under inert covers of graphene and hexagonal boron nitride prepared on Rh(111)显示文摘进 graphene 和它的支持的底层的接口的金属原子的置闰为削弱联合并且构造金属的接口的缘故成为了一个吸引人的话题在惰性的封面下面的原子层。然而,这新奇行为很少在类似的六角形的硼氮化物(h-BN ) 上被报导了在金属底层上综合了。这里,我们描述 Mn 置闰的比较研究进 graphene/Rh (111 ) 和 h-BN/Rh (111 ) 的接口,由使用解决 atomically 的扫描通道显微镜学(STM ) 和密度功能的理论(DFT ) 计算。置闰被退火执行同样扔的 Mn 簇,和进 h-BN/Rh (111 ) 的 Mn 置闰的开始的温度被发现是 80 瑩 ?? 数歡瀠睯牥搠湥楳祴漠 ??? ″坭洯吗? | Yu Zhang Yanfeng Zhang Donglin Ma Qingqing Ji Wei Fang Jianping Shi Teng Gao Mengxi Liu Yabo Gao Yubin Chen Limei Xu Zhongfan Liu | 2013 | Nano Research2013，6，12： | 2 |
| 7 | Molecular modulating of cobalt phthalocyanines on aminofunctionalized carbon nanotubes for enhanced electrocatalytic CO_(2)conversion显示文摘Metal porphyrins and metal phthalocyanines(Pc)constitute a promising class of metal molecular catalysts(MMCs)for efficient CO_(2)-to-CO electrocatalytic conversion due to their well-defined molecular structures.How to adjust the local coordination and electronic environment of the metal center and enhance the molecular-level dispersion of the active components remains as great challenges for further improving the performance.Herein,a cobalt(II)Pc(CoPc)-COOH/carbon nanotube(CNT)-NH_(2)hybrid catalyst was rationally designed by clicking the CoPc-COOH molecules onto the surface of CNT-NH_(2)through amidation reaction.This novel hybrid catalyst exhibited the enhanced current density of 22.4 mA/cm2 and CO selectivity of 91%at−0.88 V vs.reversible hydrogen electrode(RHE)in the CO_(2)electroreduction,as compared with CoPc-COOH/CNT and CoPc/CNT samples.The superior activity was ascribed to the charge transfer induced by introduction of-COOH and-NH_(2)functional groups to CoPc and CNT,respectively,facilitating the active centers of CoI being generated at lower potentials,and leading to the highest turnover frequency(TOF)being obtained over the CoPc-COOH/CNT-NH_(2)hybrid catalyst.The inherent directivity and saturability of covalent bonds formed via the amidation reaction ensure not only a higher density of Co active centers,but also an improved stability for CO_(2)reduction reaction(CO_(2)RR).The present study represents an effective strategy for improving MMCs performance by molecular modulating of metal phthalocyanines on functionalized carbon substrates directed by click confinement chemistry. | Huajian Xu Huizhu Cai Linxia Cui Limei Yu Rui Gao Chuan Shi | 2023 | Nano Research2023，16，3： | 2 |
| 8 | Mercury in traditional midicine:Is cinnabar toxicologicaolly similar to mercurial 显示文摘 | Liu J Shi Jingzhen Yu Limei | 2008 | Exp Biol Med2008，233，7： | 1 |
| 9 | Specific association between bacteria and buoyant M icrocystis colonies compared with other bulk bacterial communities in the eutrophic L ake T aihu, C hina显示文摘 | Limei Shi Yuanfeng Cai Fanxiang Kong Yang Yu | 2012 | Environmental Microbiology Reports2012，，6： | 1 |
| 10 | Mechanical behavior of starch/silicone oil/silicone rubber hybrid electric elastomer显示文摘 | Hao Limei Shi Zhanhua Zhao Xiaopeng | 2009 | Reactive & Functional Polymers2009，69，： | 1 |
| 11 | Therapeutic effcacy of a tuberculosis DNA vaccineencoding heat shockprotein 65 of Mycobacterium tuberculosis and the human interleukin 2 fusion gene显示文摘 | Shi Changhong Zhang Hal Wang Limei | 2009 | Tuberculosis2009，89，： | 1 |
| 12 | Therapeutic efficacy of a tuberculosis DNA vaccine encoding heat shock protein 65 of Mycobacterium tu- berculosis and the human interleukin 2 fusion gene 显示文摘 | Shi C Hai Z Limei W | 2009 | Tuberculosis (Edinb)2009，89，： | 1 |
| 13 | Identification of Ni_xS_y on Industrial Spent S Zorb Sorbents by Using XPS and TPR-MS显示文摘Three industrial spent S Zorb sorbents extracted from production line were studied with XRD, TPR-MS and XPS. The characterization results of XPS and TPR-MS identified the existence of amorphous Ni_xS_y on industrial spent S Zorb sorbents, while the existing XRD quantitative analysis methods can only provide the long-range order in phase information and the grain size of Ni metal. XPS is a powerful tool to investigate the chemical states of nickel atom and the depthwise distribution of nickel species on S Zorb sorbent. Ni_xS_y and Ni metal species coexist on the industrial spent sorbents, and their percentages to total nickel slightly change with the operating conditions in the surface layer. It proves that Ni_xS_y is a stable intermediate product rather than a transition state. The information can contribute to the better elucidation of S Zorb desulfurization mechanism and offer a new direction for selectivity optimization of industrial S Zorb sorbents. | Yuan Hui Qiu Limei Xu Guangtong Xin Mudi Shi Yanqiang Chen Shuai Zou Kang | 2018 | China Petroleum Processing & Petrochemical Technology2018，20，3： | 1 |
| 14 | Mercury in traditional medicines: Is cinnabar toxicologically similar to common mercurials 显示文摘 | Liu Jie Shi Jingzheng Yu Limei | 2008 | Exp Biol Med2008，233，7： | 1 |
| 15 | Mercury in traditionalmidicine : Is cinnabar toxicologicaolly similar to mercurial显示文摘 | Liu J Shi Jingzhen Yu Limei | 2008 | Exp Biol Med2008，233，7： | 1 |
| 16 | Immunogenicity and protective efficacy of a DNA vaccine encoding the fusion protein of mycobacterium heat shock protein 65 with interleukin-2 against Mycobacterium tuberculosis in BALB/c mice 显示文摘 | Limei Wang Yinlan Bai Changhong Shi | 2008 | APMIS2008，116，： | 1 |
| 17 | Therapeutic efficacy of a tuberculosisDNA vaccine encoding heat shock protein 65 of Myeobaeterium tu-berculosis and the human interleukin 2 fusion gene 显示文摘 | Shi C Hai Z Limei W | 2009 | Tuberculosis(Edinb)2009，89，： | 1 |
| 18 | Application value of Qisexingtai hand diagnostic method in diagnosis of coronary artery disease显示文摘OBJECTIVE:To evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method in the diagnosis of coronary artery disease(CAD).METHODS:This was an investigator-initiated,prospective,multi-center,cross-sectional study.All the participants from three hospitals in China had been diagnosed by both Qisexingtai hand diagnostic method and coronary angiography.We compared the two diagnostic methods to calculate the sensitivity,the specificity,the omission diagnostic rate,the mistaken diagnostic rate and accuracy in order to evaluate the diagnostic efficacy of Qisexingtai hand diagnostic method for CAD.RESULTS:A total of 326 subjects were enrolled,diagnosed by both Qisexingtai hand diagnostic method and coronary angiography.As a result,there were 166 positive cases according to Qisexingtai hand diagnostic method,and 131 positive cases according to coronary angiography.Compared with the results of coronary angiography,the sensitivity of Qisexingtai hand diagnostic method was 80.2%,the specificity was 68.7%,the omission diagnostic rate was 19.8%,the mistaken diagnostic rate was 31.3%,and the accuracy was 73.3%.Area under the receiver operating characteristic curve was estimated as 0.735 for all,and 0.718,0.735,0.783 for the three sub-centers.CONCLUSION:Qisexingtai hand diagnostic method with high accuracy and sensitivity has certain application value in the diagnosis of CAD. | LIU Qian ZHAO Zhupei GUO Hua WANG Shiheng HAO Mingzhao QIN Peijie WANG Liuqing LIU Xuechun ZHANG Fengxia AN Hong LI Yu SHI Xueqin ZHU Tingyu LIU Jianfeng WANG Liying XU Tao ZHANG Limei ZOU Xu | 2022 | Journal of Traditional Chinese Medicine2022，42，5： | 0 |
| 19 | Genetic and lipidomic analyses reveal the key role of lipid metabolism for cold tolerance in maize显示文摘Lipid remodeling is crucial for cold tolerance in plants.However,the precise alternations of lipidomics during cold responses remain elusive,especially in maize(Zea mays L.).In addition,the key genes responsible for cold tolerance in maize lipid metabolism have not been identified.Here,we integrate lipidomic,transcriptomic,and genetic analysis to determine the profile of lipid remodeling caused by cold stress.We find that the homeostasis of cellular lipid metabolism is essential for maintaining cold tolerance of maize.Also,we detect 210 lipid species belonging to 13 major classes,covering phospholipids,glycerides,glycolipids,and free fatty acids.Various lipid metabolites undergo specific and selective alterations in response to cold stress,especially mono-/di-unsaturated lysophosphatidic acid,lysophosphatidylcholine,phosphatidylcholine,and phosphatidylinositol,as well as polyunsaturated phosphatidic acid,monogalactosyldiacylglycerol,diacylglycerol,and triacylglycerol.In addition,we identify a subset of key enzymes,including ketoacyl-acyl-carrier protein synthase II(KAS II),acyl-carrier protein 2(ACP2),male sterility33(Ms33),and stearoyl-acyl-carrier protein desaturase 2(SAD2)involved in glycerolipid biosynthetic pathways are positive regulators of maize cold tolerance.These results reveal a comprehensive lipidomic profile during the cold response of maize and provide genetic resources for enhancing cold tolerance in crops. | Lei Gao Haifang Jiang Minze Li Danfeng Wang Hongtao Xiang Rong Zeng Limei Chen Xiaoyan Zhang Jianru Zuo Shuhua Yang Yiting Shi | 2024 | Journal of Genetics and Genomics2024，51，3： | 0 |
| 20 | Discovery of Novel Tricyclic 5H-Pyridazino[4,5-b]indoles as Potent Antitumor Agents: Design, Synthesis and Biological Evaluation显示文摘 | ZHAI Xin WANG Limei SHI Jiyue GONG Ping | 2015 | Chemical Research in Chinese Universities2015，31，3： | 0 |
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