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| 1 | Wheat genomic study for genetic improvement of traits in China显示文摘Bread wheat(Triticum aestivum L.)is a major crop that feeds 40%of the world’s population.Over the past several decades,advances in genomics have led to tremendous achievements in understanding the origin and domestication of wheat,and the genetic basis of agronomically important traits,which promote the breeding of elite varieties.In this review,we focus on progress that has been made in genomic research and genetic improvement of traits such as grain yield,end-use traits,flowering regulation,nutrient use efficiency,and biotic and abiotic stress responses,and various breeding strategies that contributed mainly by Chinese scientists.Functional genomic research in wheat is entering a new era with the availability of multiple reference wheat genome assemblies and the development of cutting-edge technologies such as precise genome editing tools,highthroughput phenotyping platforms,sequencing-based cloning strategies,high-efficiency genetic transformation systems,and speed-breeding facilities.These insights will further extend our understanding of the molecular mechanisms and regulatory networks underlying agronomic traits and facilitate the breeding process,ultimately contributing to more sustainable agriculture in China and throughout the world. | Jun Xiao Bao Liu Yingyin Yao Zifeng Guo Haiyan Jia Lingrang Kong Aimin Zhang Wujun Ma Zhongfu Ni Shengbao Xu Fei Lu Yuannian Jiao Wuyun Yang Xuelei Lin Silong Sun Zefu Lu Lifeng Gao Guangyao Zhao Shuanghe Cao Qian Chen Kunpu Zhang Mengcheng Wang Meng Wang Zhaorong Hu Weilong Guo Guoqiang Li Xin Ma Junming Li Fangpu Han Xiangdong Fu Zhengqiang Ma Daowen Wang Xueyong Zhang Hong-Qing Ling Guangmin Xia Yiping Tong Zhiyong Liu Zhonghu He Jizeng Jia Kang Chong | 2022 | Science China(Life Sciences)2022，65，9： | 9 |
| 2 | Translational Informatics for Parkinson’s Disease:from Big Biomedical Data to Small Actionable Alterations显示文摘Parkinson’s disease(PD)is a common neurological disease in elderly people,and its morbidity and mortality are increasing with the advent of global ageing.The traditional paradigm of moving from small data to big data in biomedical research is shifting toward big data-based identification of small actionable alterations.To highlight the use of big data for precision PD medicine,we review PD big data and informatics for the translation of basic PD research to clinical applications.We emphasize some key findings in clinically actionable changes,such as susceptibility genetic variations for PD risk population screening,biomarkers for the diagnosis and stratification of PD patients,risk factors for PD,and lifestyles for the prevention of PD.The challenges associated with the collection,storage,and modelling of diverse big data for PD precision medicine and healthcare are also summarized.Future perspectives on systems modelling and intelligent medicine for PD monitoring,diagnosis,treatment,and healthcare are discussed in the end. | Bairong Shen Yuxin Lin Cheng Bi Shengrong Zhou Zhongchen Bai Guangmin Zheng Jing Zhou | 2019 | Genomics, Proteomics & Bioinformatics2019，17，4： | 2 |
| 3 | Arabidopsis DREB1A/CBF3 bestowed transgenic tall fescue increased tolerance to drought stress显示文摘 | Junsheng Zhao Wei Ren Daying Zhi Lin Wang Guangmin Xia | 2007 | Plant Cell Reports2007，，9： | 1 |
| 4 | Ca^(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance plasma membrane H^(+)-ATPase activity and alkali stress tolerance by inhibiting PP2C-mediated dephosphorylation of TaHA2 in wheat显示文摘Alkali stress is a major constraint for crop production in many regions of saline-alkali land.However,little is known about the mechanisms through which wheat responds to alkali stress.In this study,we identified a calcium ion-binding protein from wheat,TaCCD1,which is critical for regulating the plasma membrane(PM)H^(+)-ATPase-mediated alkali stress response.PM H+-ATPase activity is closely related to alkali tolerance in the wheat variety Shanrong 4(SR4).We found that two D-clade type 2C protein phosphatases,TaPP2C.D1 and TaPP2C.D8(TaPP2C.D1/8),negatively modulate alkali stress tolerance by dephosphorylating the penultimate threonine residue(Thr926)of TaHA2 and thereby inhibiting PM H+-ATPase activity.Alkali stress induces the expression of TaCCD1 in SR4,and TaCCD1 interacts with TaSAUR215,an early auxin-responsive protein.These responses are both dependent on calcium signaling triggered by alkali stress.TaCCD1 enhances the inhibitory effect of TaSAUR215 on TaPP2C.D1/8 activity,thereby promoting the activity of the PM H^(+)-ATPase TaHA2 and alkali stress tolerance in wheat.Functional and genetic analyses verified the effects of these genes in response to alkali stress,indicating that TaPP2C.D1/8 function downstream of TaSAUR215 and TaCCD1.Collectively,this study uncovers a new signaling pathway that regulates wheat responses to alkali stress,in which Ca^(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance PM H+-ATPase activity and alkali stress tolerance by inhibiting TaPP2C.D1/8-mediated dephosphorylation of PM H+-ATPase TaHA2 in wheat. | Minghan Cui Yanping Li Jianhang Li Fengxiang Yin Xiangyu Chen Lumin Qin Lin Wei Guangmin Xia Shuwei Liu | 2023 | Molecular Plant2023，16，3： | 1 |
| 5 | Arabidopsis DREB1A/CBF3 bestowed transgenic tall fescue increased tolerance to drought stress显示文摘 | Junsheng Zhao Wei Ren Daying Zhi Lin Wang Guangmin Xia | 2007 | Plant Cell Reports2007，，9： | 1 |
| 6 | Evolutionary Programming Made Faster显示文摘 | Yao Xin Liu Yong Lin Guangmin | 1999 | IEEE Transactions on Evolutionary Computation1999，3，2： | 1 |
| 7 | Synergies between microsites of plant communities and steady-stage alpine meadows on the Qinghai-Tibetan Plateau显示文摘Background:Due to the effects of climate change and overgrazing in recent decades,alternative stable states in the alpine Kobresia meadow degradation process have coexisted in the same geographical and climatic environment,with variations occurring among microsites.Methods:We used a space-for-time substitution approach to explore the synergies of microsite variation according to its numerical characteristics and the proportion of each stable state at various stages of succession in alpine Kobresia meadows on the Qinghai-Tibetan Plateau.Results:(1)The highest average aboveground biomass in summer was 196.2±20.3 gm-2,with significantly higher levels of biomass in≤3.65 sheep unit ha-1 than in other levels of grazing intensity,while the parameters showed no significant differences among grazing intensity levels in>3.65 sheep unit ha-1.(2)The importance of plant functional groups,aboveground biomass,and niche breadth of Poaceae and Cyperaceae significantly decreased as the grazing intensity increased.(3)The effects of≥0°C accumulated temperature,total precipitation,altitude,longitude,and latitude cumulatively contributed less than 20%of the variation in the distribution of functional group characteristics across microsites.Conclusions:(1)Overgrazing decreases primary production in alpine Kobresia meadows,but ecosystem responses regulate plant community structure and botanical components so as to partially counteract grazing disturbance.(2)Overgrazing changed the proportion of microsites,which in turn led to regime shift in the plant community and subsequent synergies between the microsites of plant communities and their stable states. | Li Lin Xingliang Xu Guangmin Cao Fawei Zhang Yikang Li Bo Fan Qian Li Junjie Huang | 2023 | Grassland Research2023，2，4： | 0 |
| 8 | Effect of Spraying Liquid Mineral Mixed Fertilizers on the Mineral Elements of Potted Poa crymophila cv. Qinghai显示文摘[Objective] The aim was to explain the accumulation characteristic of mineral elements in alpine grassland plants and the effect of supplementary supply on the nutrient changes of mineral elements. [Method]Potted Poa crymophila cv. Qinghai plants were regularly applied with liquid mineral mixed fertilizers,and samples were collected for analysis and detection. [Result] After the regular spraying of liquid mineral mixed fertilizers,the mineral elements in potted P. crymophila and its soil reduced( P < 0. 05),but the accumulation of corresponding mineral elements of P. crymophila in the control group was increased due to the ' Starvation Effect',which was one of the endogenetic forces driving the increase in the accumulation of mineral elements. [Conclusion]This study is of great significance for the study of the accumulation of mineral elements in degraded grassland plants and its dynamic mechanism,as well as testing the hypothesis of the Starvation Effect of mineral elements. In addition,it also provides scientific bases and technical support for the restoration and remediation of degraded grassland and the development of ecological livestock husbandry. | Tiancai LI Guangmin CAO Li LIN Xiaowei GUO Yikang LI | 2018 | Agricultural Biotechnology2018，7，5： | 0 |
| 9 | Self-stabilizing maintenance process in plant communities of alpine meadows under different grazing intensities显示文摘Backgrounds:Grazing prohibition and reduced grazing intensity,as two important“vegetation close-to-nature recovery”methods,have been suggested as economical and effective technologies for enhancing forage production.However,numerous studies have found that the yield of forage could be increased by removing or reducing grazing in a short time in some steady stage of alpine Kobresia meadows,but not in others.To reveal the mechanism behind this phenomenon,we proposed a series of experiments.Methods:We monitored the plant and soil characteristics in the key steady stages of Kobresia meadows under reduced and prohibited grazing conditions in the same geographic and climatic environments in the northeastern Qinghai-Tibet Plateau for 6 years.We estimated the relationships between the plant community and soil nutrients and obtained the following results.Results:All measured variables were positively correlated with each other.The plant community structure had higher path coefficients to aboveground biomass,soil organic matter,total nitrogen,and nitrate nitrogen than to other factors.The plant community structure played an important role in response to grazing intensity.Different plant functional groups(PFGs)had different responses to grazing intensity,which led to plant community re-establishment or re-organization under different grazing intensities.Poaceae and Kobresia were more sensitive to grazing intensity than other PFGs,and the ratio of Kobresia biomass(including Kobresia humilis and Kobresia pygmaea)to the total biomass of Poaceae and Kobresia could be used as an indicator of regime shifts within plant communities.With Kobresia pygmaea as the dominant species,the prohibition of grazing was not an efficient approach to increase the yield in the steady stages because this treatment needed more time to recover aboveground biomass.If Poaceae is the dominant PFG,grazing should only be prohibited for 3 years in the steady stages because the aboveground biomass will decrease if grazing is prohibited for more than 3 years.Conclusions:Therefore,the different steady stages of alpine meadows require different recovery methods to increase recovery efficiency and speed. | Li Lin Xingliang Xu Guangmin Cao Fawei Zhang Yikang Li Junjie Huang | 2023 | Grassland Research2023，2，2： | 0 |
| 10 | Characterizing nitric oxide emissions from two typical alpine ecosystems显示文摘portion of alpine meadows has been and will continue to be cultivated due to the concurrent increasing demands for animal-and crop-oriented foods and global warming.However, it remains unclear how these long-term changes in land use will affect nitric oxide(NO) emission. At a field site with a calcareous soil on the Qinghai-Tibetan Plateau,the authors measured the year-round NO fluxes and related variables in a typically wintergrazed natural alpine meadow(NAM) and its adjacent forage oat field(FOF). The results showed that long-term plow tillage, fertilization and growing forage oats significantly yielded ca. 2.7 times more(p < 0.01) NO emissions from the FOF than the NAM(conservatively 208 vs. 56 g N/(ha·year) on average). The spring freeze–thaw period and non-growing season accounted for 17%-35% of the annual emissions, respectively. The Q10 of surface soil temperature(Ts) was 8.9 in the NAM(vs. 3.8 in the FOF), indicating increases of 24%–93% in NO emissions per 1–3 °C increase. However, the warming-induced increases could be smaller than those due to land use change and management practices. The Tsand concentrations of ammonium, nitrate and water-extractable organic carbon jointly explained 69% of the variance in daily NO fluxes from both fields during the annual period(p < 0.001). This result indicates that temporally and/or spatially distributed NO fluxes from landscapes with calcareous soils across native alpine meadows and/or fields cultivated with forage oats can be predicted by simultaneous observations of these four soil variables. | Fei Lin Chunyan Liu Xiaoxia Hu Yongfeng Fu Xunhua Zheng Rui Wang Wei Zhang Guangmin Cao | 2019 | Journal of Environmental Sciences2019，31，3： | 0 |
| 11 | 高寒小嵩草草甸可能成为青藏高原相同地理和气候单元下多种类型草地的偏途演替状态显示文摘高寒嵩草(Kobresia)草甸是青藏高原冬春放牧草场的主体,在放牧强度分异的条件下可以形成特征迥异的稳态。然而,目前还不清楚在不同放牧强度下其他类型草地是否可以演替成为这些稳态。本研究通过土壤剖面特征推断其历史植物群落特征,以植物群落现场调查确定其现实植物群落特征,以非结构式问卷调查确定草地放牧强度,采用多元回归树模型分析导致草地稳态转化的节点。研究结果表明,高寒灌丛草甸和旱化沼泽草甸在过度放牧条件下均可转化成为高寒矮嵩草(K.humilis)草甸和高寒小嵩草(K.pygmaea)草甸,从而使高寒灌丛草甸和旱化沼泽化草甸进入高寒矮嵩草草甸退化演替序列,最终转化成为黑土滩-杂类草次生裸地。以放牧强度为分节点,最多可以将这些植物群落划分为4类稳态,各稳态转化的节点依次为11.0、8.0、5.5羊/ha。所有研究草地总体表现为随放牧强度的增高地上总生物量呈下降趋势。其中,11.0羊/ha是草地转化成为黑土滩杂类草次生裸地的节点。放牧强度改变可以影响植物群落特征及其演替方向,进而改变草地的畜牧生产服务能力,因此放牧强度可以作为反映牧场畜牧生产服务能力的表观指标。未来牧场的可持续发展策略应以草畜平衡为主,合理控制放牧强度,增加草地生产附加值和延伸畜牧业产业链以实现区域草场生态和生产效益的双赢。 | Li Lin Guangmin Cao Xingliang Xu Fawei Zhang Junjie Huang Bo Fan Bencuo Li Yikang Li | 2023 | Journal of Plant Ecology2023，16，5： | 0 |
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