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| 1 | Taxonomic composition, abundance and biomass of mesozooplankton in the Zhelin Bay—an estuary with intensive aquaculture显示文摘The Zhelin Bay is an estuary that supports intensive aquaculture in South China. Aside from traditional nutrient inputs derived from waste water and agriculture, the increased intensification of aquaculture has accelerated eutrophication during the past decade, jeopardizing aquacultural production. Annual variations of mesozooplankton in the Zhelin Bay were described, providing baseline data for long-term ecological studies. The taxonomic composition, abundance and biomass of mesozooplankton were studied monthly from July 2001 to July 2002 at 19 stations. Collections yielded 73 taxa, including 60 species of copepods, three species of cladocerans, as well as tunicates, chaetognaths, polychaetes, medusae, ostracods, rotatori, amphipods, planktonic mollusks, pelagic larvae, and planktonic shrimps. The Zhelin Bay was dominated by small mesozooplankton, with 76% of the species smaller than 1.4 mm, and 97% of the individuals smaller than 1.0 mm. Dominant species (Paracalanus crassirostris, Oithona brevicornis,and Penilia avirostris) accounting for 60% of the total abundance were less than 0.6 mm in body length. Species diversity, biomass, and total abundance of mesozooplankton were greater in the samples collected outside the bay than inside the bay. Samples from the outer and eastern boundaries of the bay had greater biomass, diversity, and abundance than those from the inner and western boundaries. Total abundance and biomass had a unimodal annual pattern and were the greatest in August 2001 when water temperature was maximum, and the least in February 2002 when water temperature was minimum. Canonical correspondence analysis (CCA) revealed that temperature, turbidity, nutrients and salinity were the main determinants of spatial and temporal distributions of mesozooplankton in the Zhelin Bay, and six distinct zones were identified across the 19 sampling stations. | DONG Qiaoxiang LIN Xiaoping HE Xin KELSO WE HUANG Changjiang | 2006 | Acta Oceanologica Sinica2006，25，5： | 3 |
| 2 | High-resolution X-ray diffraction and transmission electron microscopy of multiferroic BiFeO3 films 显示文摘 | QI X D WE M LIN Y | 2005 | Appl Phys Lett2005，86，07： | 1 |
| 3 | Wild-type-like viral replication potential of human immunodeficiency virus type 1 envelope mutants lacking palmitoylation signals显示文摘 | Chan WE Lin HH Chen SS | 2005 | J Virol2005，79，13： | 1 |
| 4 | Intrarenal angiotensin Ⅱ is associated with inflammation,renal damage and dysfunction in dahl salt-sensitive hypertension显示文摘 | Lin L Phillips WE Manning RD | 2009 | J Am Soc Hypertens2009，3，5： | 1 |
| 5 | Lower extremity biomechanics during the landing of a stop-jump task 显示文摘 | Yu B Lin CF Garrett WE | 2006 | Clin Biomech2006，21，3： | 1 |
| 6 | Removal of EATX from waste gases by a trickle bed air biofiher显示文摘 | Lu C Lin M R We Y | 2001 | Environmental and Engeering2001，127，10： | 1 |
| 7 | Intrarenal angiotensinlI is asscoiated with inlfammation,renal damage and dysfunction in Dalai saltsensitive hypertension显示文摘 | L Lin WE Phillips RD Manning | 2009 | Journal of the American society of hypertension2009，3，5： | 1 |
| 8 | Drp1-dependent remodeling of mitochondrial morphology triggered by EBV-LMP1 increases cisplatin resistance显示文摘Latent membrane protein 1(LMP1)is a major Epstein–Barr virus(EBV)-encoded oncoprotein involved in latency infection that regulates mitochondrial functions to facilitate cell survival.Recently,mitochondrial fission has been demonstrated as a crucial mechanism in oncovirus-mediated carcinogenesis.Mitochondrial dynamin-related protein 1(Drp1)-mediated mitochondrial fission has an impact on the chemoresistance of cancers.However,the mechanism by which oncogenic stress promotes mitochondrial fission,potentially contributing to tumorigenesis,is not entirely understood.The role of Drp1 in the oncogenesis and prognosis of EBV-LMP1-positive nasopharyngeal carcinoma(NPC)was determined in our study.We show that EBV-LMP1 exhibits a new function in remodeling mitochondrial morphology by activating Drp1.A high level of p-Drp1(Ser616)or a low level of p-Drp1(Ser637)correlates with poor overall survival and disease-free survival.Furthermore,the protein level of p-Drp1(Ser616)is related to the clinical stage(TNM stage)of NPC.Targeting Drp1 impairs mitochondrial function and induces cell death in LMP1-positive NPC cells.In addition,EBV-LMP1 regulates Drp1 through two oncogenic signaling axes,AMPK and cyclin B1/Cdk1,which promote cell survival and cisplatin resistance in NPC.Our findings provide novel insight into the role of EBV-LMP1-driven mitochondrial fission in regulating Drp1 phosphorylation at serine 616 and serine 637.Disruption of Drp1 could be a promising therapeutic strategy for LMP1-positive NPC. | Longlong Xie Feng Shi Yueshuo Li We Li Xinfang Yu Lin Zhao Min Zhou Jianmin Hu Xiangjian Luo Min Tang Jia Fan Jian Zhou Qiang Gao Weizhong Wu Xin Zhang Weihua Liao Ann MBode Ya Cao | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 1 |
| 9 | Identification of tyrosine kinases overexpressed in head and neck cancer显示文摘 | Lin HS Berry GJ Fee WE Jr | 2004 | Arch Otolaryngol Head Neck Surg2004，130，3： | 1 |
| 10 | Airway management after maxillectomy: routine tracheostomy is unnecessary 显示文摘 | Lin HS Wang D Fee WE | 2003 | Laryngoscope2003，113，6： | 1 |
| 11 | Biochemical and functional effects of prenatal and postnatal n-3 fatty acid deficiency on retina and brain in rhesus monkeys显示文摘 | Neuringer M Conner WE Lin DS | 1986 | Proc Natl Sci USA1986，83，11： | 1 |
| 12 | Accumulation of tissue advanced glycation end products correlated with glucose exposure dose and associated with cardiovascular morbidity in patients on peritoneal dialysis显示文摘 | Jianping Jiang Pingyan Chen Jianghua Chen Xueqing Yu Di Xie Changlin Mei Fei Xiong Wei Shi Wei Zhou Xusheng Liu Shiren Sun Ping Zhang Xiao Yang Yixiang Zhang Yanmin Zhang Xinling Liang Zhimin Zhang Qizhan Lin Yan Yu Toshio Miyata Jianwei Tian Min Liang We | 2012 | Atherosclerosis2012，，1： | 1 |
| 13 | The urokinase - type plasminogen activator (uPA) system as a biomarkerand therapeutic target in human malignancies显示文摘 | Su SC Lin CW Yang WE | 2015 | Expert Opin Ther Targets2015，14，： | 1 |
| 14 | Airway management after maxillectomy: routine tracheostomy is unnecessary显示文摘 | Wang D Fee WE | 2003 | Laryngoscope2003，113，6： | 1 |
| 15 | Reactive power optimisation with voltage stability consideration in power market systems显示文摘 | Lin X David A K Yu C We t al | 2003 | IEE Proceedings-Generation Transmission&Distribu-tion2003，50，3： | 1 |
| 16 | Construction of antithrombogenic polyelcctrolyte muhilayer on thermoplastic polyurethane via layer- by-layer self-assembly technique显示文摘 | Yu DG Lin WE Lin CH | 2007 | J Biomed Mater Res B Appl Biomater2007，83，1： | 1 |
| 17 | Lower extremity biomechanics during the landing of a stop-jump task显示文摘 | Yu B Lin CF Garrett WE | 2006 | Clin Biomech2006，21，3： | 1 |
| 18 | Risk assessment of hemorrhagic transformation of acute middle cerebral artery stroke using multimodal CT显示文摘 | Lin K Zink WE Tsiouris AJ | 2012 | J Neuroimaging2012，22，2： | 1 |
| 19 | What ASPECTS value best predicts the 100 - ml threshold on diffusion weighted imaging study of 150 patients with middle cerebral arte stroke 显示文摘 | Lin K Lee SA Zink WE | 2011 | J Neuroimaging2011，21，3： | 1 |
| 20 | Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720 显示文摘 | Hale JJ Lin Y Neway WE | 2004 | Bioorg Med Chem2004，12，： | 1 |
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