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| 1 | In vitro degradation and biocompatibility of Mg-Nd-Zn-Zr alloy显示文摘In this study,in vitro degradation and biocompatibility of Mg-Nd-Zn-Zr(NZK) alloy were investigated to determine its suitability as a degradable medical biomaterial.Its corrosion properties were evaluated by static immersion test,electrochemical corrosion test,scanning electron microscopy(SEM),and energy dispersive spectroscopic(EDS) analysis,and in vitro biocompatibilities were assessed by hemolysis and cytotoxicity tests.Pure magnesium was used as control.The results of static immersion test and electrochemical corrosion test in simulated body fluid(SBF) demonstrated that the addition of alloying elements could improve the corrosion resistance.The hemolysis test found that the hemolysis rate of calcium phosphate coated NZK alloy was 4.8%,which was lower than the safe value of 5%.The cytotoxicity test indicated that NZK alloy extracts did not significantly reduce MC3T3-E1 cell viability.Hemolysis test and cytotoxicity test display excellent hemocompatibility and cytocompatibility of NZK alloy in vitro.Our data indicate that NZK alloy has excellent biocompatibility and thus can be considered as a potential degradable medical biomaterial for orthopedic applications. | WANG YongPing HE YaoHua ZHU ZhaoJin JIANG Yao ZHANG Jian NIU JiaLin MAO Lin YUAN GuangYin | 2012 | Chinese Science Bulletin2012，57，17： | 8 |
| 2 | Statolith Morphology of the Sthenoteuthis oualaniensis in the Central South China Sea显示文摘The morphology,microstructure and demographic parameters of statolith of Sthenoteuthis oualaniensis were studied from 90 individuals captured in the central South China Sea in September and October,2012. The morphologic results showed that the statolith has great lateral dome and wing dome,small dorsal dome,and long narrow rostrum dome. S. Oualaniensis could be divided into three populations by statolith morphology in the central South China Sea. Five most important featured parameters including total statolith length( TSL),wing length( WL),maximum width( MW) were described by logarithmic functions with mental length( ML)( P < 0. 05); rostrum length( RSL),dorsolateral length( DLL) were described by linear functions with ML( P < 0. 05). With the squid growth,the size of statolith gradually develops,while the ratio of each featured parameter to ML slowly decreases,the ratio of DLL,LDL,RSL and WL to TSL almost remain the same level,corresponding to 48. 05%,60. 05%,35. 44%,67. 59%,and the ratio of LDL and WL to SL show little higher. | Jiang Yan'e Chen Zuozhi Zhang Peng Lin Zhaojin Qiu Yongsong Fang Zhanqiang | 2015 | Animal Husbandry and Feed Science2015，7，5： | 1 |
| 3 | Clinical implications of ERβ methylation on sporadic breast cancers in Chinese women显示文摘 | Lin Zhao Zhaojin Yu Yunan Li Xiaoyan Wen Wenfeng Ma Lin Wang Jie Ren Caigang Liu Miao He Xuefeng Bai Mingli Sun Zhihong Zheng Xiaoyi Mi Enhua Wang Olufunmilayo I. Olopade Feng Jin Minjie Wei | 2012 | Medical Oncology2012，，3： | 1 |
| 4 | Synthesis and antiviral activities of a novel class of thioflavone and flavonoid analogues显示文摘A novel class of thioflavone and flavonoid derivatives has been prepared and their antiviral activities against enterovirus 71(EV71)and the coxsackievirus B3(CVB3)and B6(CVB6)were evaluated.Compounds 7d and 9b showed potent antiviral activities against EV71 with ICso values of 8.27 and 5.48μM,respectively.Compound 7f,which has been synthesized for the first time in this work,showed the highest level of inhibitory activity against both CVB3 and CVB6 with an ICso value of 0.62 and 0.87μM.Compounds 4b,7a,9c and 9e also showed strong inhibitory activities against both the CVB3 and CV B6 at low concentrations(IC_(50)=1.42-7.15μM),whereas compounds 4d,7c,7e and 7g showed strong activity against CVB6(IC_(50)=2.91-3.77μM)together with low levels of activity against CVB3.Compound 7d exhibited stronger inhibitory activity against CVB3(IC_(50)=6.44μM)thaln CVB6(IC_(50)>8.29μM).The thioflavone derivatives 7a,7c,7d,7e,7f and 7g,represent a new class of lead compounds for the development of novel antiviral agents. | Dajun Zhang Xingyue Ji Rongmei Gao Huiqiang Wang Shuai Meng Zhaojin Zhong Yuhuan Lin Jiandong Jiang Zhuorong Li | 2012 | Acta Pharmaceutica Sinica B2012，2，6： | 0 |
| 5 | Seasonal variations in diversity and abundance of surface ichthyoplankton in the northern South China Sea显示文摘The objective of this study was to investigate the seasonal variations of ichthyoplankton diversity and abundance in the northern South China Sea based on the data collected during summer, winter and spring. In total, 95 taxa of larval fishes were identified. The greatest number of species was recorded in spring, followed by summer and winter. The number of species was distributed mainly in the coastal waters from the east of Leizhou Peninsula to the southeast of Hainan Island during the surveyed periods of summer and spring, but in the offshore waters during winter. The abundance of larval fish was lowest in winter, increased in spring, and reached the maximum in summer. High abundance of larval fish was generally restricted to coastal waters with the isobaths less than 50 m. Seasonal variations of larval fish richness, abundance and diversity index were significant(P<0.001). Carangidae was the most common and abundant taxon in summer and winter, while Sardinella sp., Thrissa mystax and Leiognathus sp. were dominant in spring. High diversity and abundance of larval fish might be attributed to increased temperature and coastal upwelling in spring and summer. | LI Kaizhi YIN Jianqiang HUANG Liangmin LIN Zhaojin | 2014 | Acta Oceanologica Sinica2014，33，12： | 0 |
| 6 | Progress of Planetary Science in China显示文摘The national and international progress in deep space exploration has greatly promoted the development of planetary science in China.Substantial progress in different areas of planetary science has been achieved in 2020-2022.In this report,we summarize the research achievements obtained in China in the last three years.The achievements include the research on geology,geochemistry,and space physics of the Moon,Mars,Mercury,Venus,giant planets,asteroids,and comets.The recent work on science objectives,mission payloads,and analytical capabilities that supports the lunar and deep space exploration program of China has also been introduced in this report.Finally,we report the progress on developments of discipline and research team of planetary science in China. | HUI Hejiu RONG Zhaojin ZHANG Jinhai HU Sen LIN Honglei WEI Yong LIN Yangting | 2022 | 空间科学学报2022，42，4： | 0 |
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