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| 1 | Joint utilization of genetic analysis and semi-cloning technology reveals a digenic etiology of Müllerian anomalies显示文摘Dear Editor,Identifying pathogenic gene mutations and their combination is critical but challenging in dissecting the etiology of complex diseases when more than one gene is involved.1 The digenic/oligogenic/omnigenic models,holding that more than one gene could act synergistically,appeal to a wide range of genes responsible for complex phenotypes.1,2,3,4 These genetic models advanced our understanding of genetic factors underlying complex phenotypes,yet an accordingly rapid and efficient experimental assay for identifying pathogenic combinations of genetic variants at animal model level is lacking and urgently needed. | Lingbo Wang Ying Zhang Xiaoyi Fu Shuangshuang Dong Shuyan Tang Ning Zhang Chengcheng Song Nan Yang Lin Zhang Hongyan Wang Huijuan Shi Li Jin Feng Zhang Jinsong Li Keqin Hua | 2020 | Cell Research2020，30，1： | 8 |
| 2 | Carbon inputs regulate the temperature sensitivity of soil respiration in temperate forests显示文摘Litter and root activities may alter the temperature sensitivity(Q_(10))of soil respiration.However,existing studies have not provided a comprehensive understanding of the effects of litter and root carbon inputs on the Q_(10)of soil respiration in different seasons.In this study,we used the trench method under in situ conditions to measure the total soil respiration(R_(total)),litter-removed soil respiration(R_(no-litter)),root-removed soil respiration(R_(no-root)),and the decomposition of soil organic matter(i.e.,both litter and root removal;R_(SOM))in different seasons of pioneer(Populus davidiana Dode)and climax(Quercus liaotungensis Mary)forests on the Loess Plateau,China.Soil temperature,soil moisture,litter biomass,fine root biomass,litter carbon,and root carbon were analyzed to obtain the drive mechanism of the Q_(10)of soil respiration in the two forests.The results showed that the Q_(10)of soil respiration exhibited seasonality,and the Q_(10)of soil respiration was higher in summer.The litter enhanced the Q_(10)of soil respiration considerably more than the root did.Soil temperature,soil moisture,fine root biomass,and litter carbon were the main factors used to predict the Q_(10)of different soil respiration components.These findings indicated that factors affecting the Q_(10)of soil respiration highly depended on soil temperature and soil moisture as well as related litter and root traits in the two forests,which can improve our understanding of soil carbon–climate feedback in global warming.The results of this study can provide reference for exploring soil respiration under temperate forest restoration. | LIU Yulin LI Jiwei HAI Xuying WU Jianzhao DONG Lingbo PAN Yingjie SHANGGUAN Zhouping WANG Kaibo DENG Lei | 2022 | Journal of Arid Land2022，14，9： | 3 |
| 3 | Soil microbial respiration is regulated by stoichiometric imbalances: Evidence from a humidity gradient case显示文摘Humidity not only affects soil microbial respiration(SMR) directly, but, indirectly by regulating the availability of soil water and nutrients. However,the patterns of direct and indirect effects of humidity on SMR over large precipitation gradients remain unclear, limiting our understanding of the effects of precipitation changes on soil C cycle. Here, we investigated the relationships among humidity, soil nutrients, and SMR by identifying stoichiometric imbalances, microbial elemental homeostasis, and microbial C use efficiency along a precipitation gradient at a continental scale. The relationship between SMR and humidity index(HI) corresponded to a Richard’s curve with an inflection point threshold value of approximately 0.7. Soil microbial respiration increased with increasing humidity in drier areas(HI < 0.7), but tended to balance above this threshold. Increasing humidity exacerbated C:P and N:P imbalances across the selected gradient. Severe N and P limitations in soil microbial communities were observed in drier areas, while soil microbes suffered from aggravated P limitation as the humidity increased in wetter areas(HI > 0.7). Soil microbial communities regulated their enzyme production to maintain a strong stoichiometric homeostasis in drier areas;enzyme production, microbial biomass, and threshold elemental ratios were non-homeostatic under P limitation in wetter areas, which further contributed to the increase in SMR. Our results identified a moisture constraint on SMR in drier areas and highlighted the importance of nutrient(especially for P) limitations induced by humidity in regulating SMR in wetter areas. Understanding the modulation of SMR via soil enzyme activity may improve the prediction of soil C budget under future global climate change. | Jiwei LI Jiangbo XIE Jianzhao WU Yongxing CUI Lingbo DONG Yulin LIU Xuying HAI Yan LI Zhouping SHANGGUAN Kaibo WANG Changhui PENG Lei DENG | 2023 | Pedosphere2023，33，6： | 0 |
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