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| 1 | Direct generation of an ultrafast vortex beam in a CVD-graphene-based passively mode-locked Pr:LiYF4 visible laser显示文摘We report on the direct generation of passively mode-locked vortex lasers in the visible spectral region, for the first time to the best of our knowledge, using a Pr :Li YF4(Pr:YLF) crystal as the gain medium. A stable mode-locked TEM00 mode has been achieved with a maximum average output power of 75 m W using a graphene saturable absorber mirror. The mode-locked pulse width is measured to be as short as about 73.4 ps at a repetition rate of about 140 MHz, and the laser wavelength is at about 721 nm with spectral width of about 0.5 nm. By slightly misaligning the laser resonator, a first-order Laguerre-Gaussian mode(LG0,1) has also been obtained with output power reduced to about 22 m W. The achieved LG0,1 mode has been verified via a home made improved Fizeau interferometer. This work provides a simple and universal method for direct generation of an ultrafast vortex laser,which can be readily extended to other spectral regions by using different laser gain mediums. | Nan Li Junjie Huang Bin Xu Yaqi Cai Jie Lu Linjie Zhan Zhengqian Luo Huiying Xu Zhiping Cai Weiwei Cai | 2019 | Photonics Research2019，7，11： | 9 |
| 2 | 16 × 16 silicon Mach–Zehnder interferometer switch actuated with waveguide microheaters显示文摘We experimentally demonstrate a 16 × 16 reconfigurably nonblocking optical switch fabric using a Benes architecture. The switch fabric consists of 56 2 × 2 Mach–Zehnder interferometer based elementary switches, with each integrated with a pair of waveguide microheaters. The average on-chip insertion loss is ~5.2 dB for both of the 'all-cross' and the 'all-bar' states, with a loss variation of 1 dB over all routing paths. The cross talk for all switching states is better than -30 d B. The switching time of the switch element is about 22 μs. The switching functionality is verified by transmission of a 40 Gb∕s quadrature phase-shift keying optical signal. | Shuoyi Zhao Liangjun Lu Linjie Zhou Dong Li Zhanzhi Guo Jianping Chen | 2016 | Photonics Research2016，4，5： | 7 |
| 3 | Hexagonal boron nitride:A metal-free catalyst for deep oxidative desulfurization of fuel oils显示文摘Oxidative desulfurization(ODS)has been proved to be an efficient strategy for the production of clean fuel oil.Numerous metal-based materials have been employed as excellent ODS catalysts,but being hindered by their high-cost and potential secondary pollution.In this work,we employed graphene analogous hexagonal boron nitride(h-BN)as a metal-free catalyst for ODS with hydrogen peroxide(H2O2)as the oxidant.The h-BN catalyst was characterized and proved to be a few-layered structure with relatively high specific surface areas.The h-BN catalyst showed a 99.4%of sulfur removal in fuel oil under the optimized reaction conditions.Besides,the h-BN can be recycled for 8 times without significant decrease in the catalytic performance.Detailed mechanism analysis found that it is the boron radicals in h-BN activated H2O2 to generate·OH species,which can readily oxidize sulfides to corresponding sulfones for separation.This work would provide another choice in choosing metal-free catalysts for ODS. | Peiwen Wu Linjie Lu Jing He Linlin Chen Yanhong Chao Minqiang He Fengxia Zhu Xiaozhong Chu Huaming Li Wenshuai Zhu | 2020 | Green Energy & Environment2020，5，2： | 3 |
| 4 | 4×4 nonblocking optical switch fabric based on cascaded multimode interferometers显示文摘We experimentally demonstrate a 4 × 4 nonblocking silicon thermo-optic(TO) switch fabric consisting of three stages of tunable generalized Mach–Zehnder interferometers. All 24 routing states for nonblocking switching are characterized. The device's footprint is 4.6 mm × 1.0 mm. Measurements show that the worst cross talk of all switching states is-7.2 dB. The on-chip insertion loss is in the range of 3.7–13.1 dB. The average TO switching power consumption is 104.8 mW. | Zuxiang Li Linjie Zhou Liangjun Lu Shuoyi Zhao Dong Li Jianping Chen | 2016 | Photonics Research2016，4，1： | 2 |
| 5 | Nonvolatile waveguide transmission tuning with electrically-driven ultra-small GST phase-change material显示文摘Low-power reconfigurable optical circuits are highly demanded to satisfy a variety of different applications. Conventional electro-optic and thermo-optic refractive index tuning methods in silicon photonics are not suitable for reconfiguration of optical circuits due to their high static power consumption and volatility. We propose and demonstrate a nonvolatile tuning method by utilizing the reversible phase change property of GST integrated on top of the silicon waveguide. The phase change is enabled by applying electrical pulses to the lm-sized GST active region in a sandwich structure. The experimental results show that the optical transmission of the silicon waveguide can be tuned by controlling the phase state of GST. | Hanyu Zhang Linjie Zhou Jian Xu Ningning Wang Hao Hu Liangjun Lu B. M. A. Rahman Jianping Chen | 2019 | Science Bulletin2019，64，11： | 2 |
| 6 | 3D-printing of integrated spheres as a superior support of phosphotungstic acid for deep oxidative desulfurization of fuel显示文摘Construction of catalysts with integral structure for oxidative reaction process is an essential promotion to catalysts in industrial application.In this work,a 3D printing method was employed to prepare 3D printed spheres(3D-PSs),followed by carbonization to form 3D carbon spheres(3D-CSs).Then,a 3D-CSs supported phosphotungstic acid(HPW/3D-CSs)was prepared for deep oxidative desulfurization.Compared with traditional powder catalysts,the as-prepared catalyst is easy to be operated and separated from oil products.The supported catalyst possesses excellent catalytic performance and the removal of DBT,4-MDBT and 4,6-DMDBT in fuel oil,reaching^100%of sulfur removal.The effects of various experimental parameters on desulfurization efficiency were considered to optimize reaction conditions.Moreover,the catalyst shows excellent thermal and chemical stability,with no obvious decrease in desulfurization activity after 5 cycles.GC–MS analysis indicates DBT sulfone was the solely oxidized product of DBT. | Jie Zhu Peiwen Wu Linlin Chen Jing He Yingcheng Wu Chao Wang Yanhong Chao Linjie Lu Minqiang He Wenshuai Zhu Huaming Li | 2020 | Journal of Energy Chemistry2020，29，6： | 2 |
| 7 | 中国西南地区2007年-2011年男性乳腺癌发生率(英文)显示文摘Objective: Male breast cancer is a rare disease with an incidence of about 1% of breast cancers in USA, but relatively lack of the information of male breast cancer in China, especially in Southwest of China, led us to study its incidence trends. Methods: Chongqing is one of the biggest and the most important areas that is located in Southwest of China. There are around 31.4 million people who live in approximate 82 402.95 km2area of Chongqing. Data about breast cancer patients registered in the Center for Disease Prevention and Control of Chongqing(China) were statistically collected from 187 hospitals, about 58 hospitals in city and 129 hospitals in country, and over 6.2 million people were studied every year. It was tried to represent all the people in villages and cities in Chongqing, China. Results: The incidence of male breast cancer in Southwest of China ranged from 0.34/100 000 to 1.45/100 000 between 2007 and 2011, while the incidence of female breast cancer ranged from 15.40/100000 to 21.66/100000 at the same time. The rate of male breast cancer to female breast cancer ranged from 0.02:1 to 0.07:1, male breast cancer accounted for 1.96% to 6.5%(with the mean value of 2.9%) of breast cancers in Southwest of China from 2007 to 2010. Conclusion: In Southwest of China male breast cancer accounts for about 2.9% of breast cancers which is higher than that in United States. It is important for policy makers and health manager to seriously consider breast cancer in future plan in Southwest of China. | Liangbin Jin Linjie Lu Lingquan Kong Yang Bai Zixiang Yao Guangyan Ji Shengchun Liu Guosheng Ren Kainan Wu Hua Tang Deqiang Mao | 2013 | The Chinese-German Journal of Clinical Oncology2013，12，11： | 2 |
| 8 | Microwave frequency upconversion employing a coupling-modulated ring resonator显示文摘We present a method to generate a frequency-doubled microwave signal by employing a coupling-modulated ring resonator. Critical coupling is achieved when the resonator intrinsic loss is perfectly balanced by the external coupling enabled by a Mach–Zehnder interferometer coupler. The high suppression of the carrier leads to a clean two-tone optical signal with the frequency interval two times larger than that of the input microwave frequency.The beating of the two-tone signal at a photodiode generates the frequency upconverted microwave signal.A theoretical model is established to analyze the modulation process and the microwave signal generation.Experimental results show that the electrical harmonic suppression ratio is around ~20 dB(29 dB) for an input microwave signal with 5 dBm(10 dBm) power. | YIMING ZHONG LINJIE ZHOU YANYANG ZHOU YUJIE XIA SIQI LIU LIANGJUN LU JIANPING CHEN XINGJUN WANG | 2017 | Photonics Research2017，5，6： | 1 |
| 9 | Continuous-variable quantum key distribution with on-chip light sources显示文摘Integrated quantum key distribution(QKD)systems based on photonic chips have high scalability and stability,and are promising for further construction of global quantum communications networks.On-chip quantum light sources are a critical component of a fully integrated QKD system;especially a continuous-variable QKD(CVQKD)system based on coherent detection,which has extremely high requirements for the light sources.Here,for what we believe is the first time,we designed and fabricated two on-chip tunable lasers for CV-QKD,and demonstrated a high-performance system based on these sources.Because of the high output power,fine tunability,and narrow linewidth,the involved on-chip lasers guarantee the accurate shot-noise-limited detection of quantum signals,center wavelength alignment of nonhomologous lasers,and suppression of untrusted excess noise.The system’s secret key rate can reach 0.75 Mb/s at a 50 km fiber distance,and the secure transmission distance can exceed 100 km.Our results mark a breakthrough toward building a fully integrated CV-QKD,and pave the way for a reliable and efficient terrestrial quantum-secure metropolitan area network. | LANG LI TAO WANG XINHANG LI PENG HUANG YUYAO GUO LIANGJUN LU LINJIE ZHOU GUIHUA ZENG | 2023 | Photonics Research2023，11，4： | 0 |
| 10 | Low temperature sensitivity on-chip Fouriertransform spectrometer based on dual-layer Si_(3)N_(4)spiral waveguides显示文摘On-chip Fourier-transform spectrometers(FTSs)based on Mach–Zehnder interferometer(MZI)arrays suffer from severe central wavelength and fringe contrast variation due to fabrication errors.Even though a calibration matrix can be employed to correctly retrieve the input spectra,environmental temperature variation greatly degrades the retrieving performance.In this paper,we devise a dual-layer Si_(3)N_(4) waveguide interferometer to reduce the temperature sensitivity.The beating of the even and odd supermodes in the dual-layer waveguide generates periodic intensity fluctuations in the spectrum.Since these two modes have similar modal profiles,their thermal sensitivity and propagation loss are relatively balanced,leading to a low temperature sensitivity and a high interference extinction ratio.We designed and fabricated a passive FTS based on a 32-channel dual-layer Si_(3)N_(4) waveguide array.Experimental results show that the temperature sensitivity is reduced to 10 pm/°C,which is almost half that of single-layer Si_(3)N_(4) MZI-based FTSs.With this chip,we accurately reconstructed various types of optical spectra,including single and two sparse laser lines,and broadband optical spectra.Our method can fit a wide wavelength range,which is a promising technology to improve the practical applications of on-chip FTSs. | LIANGJUN LU HONGYI ZHANG XIN LI JIANPING CHEN LINJIE ZHOU | 2023 | Photonics Research2023，11，4： | 0 |
| 11 | Ultra-low-loss multi-layer 8×8 microring optical switch显示文摘Microring-based optical switches are promising for wavelength-selective switching with the merits of compact size and low power consumption.However,the large insertion loss,the high fabrication,and the temperature sensitivity hinder the scalability of silicon microring optical switch fabrics.In this paper,we utilize a three-dimensional(3D)microring-based optical switch element(SE)on a multi-layer Si_(3)N_(4)-on-SOI platform to realize highperformance large-scale optical switch fabrics.The 3D microring-based SE consists of a Si∕Si_(3)N_(4) waveguide overpass crossing in the bottom and the top layers,and Si_(3)N_(4) dual-coupled microring resonators(MRRs)in the middle layer.The switch is calibration-free and has low insertion loss.With the 3D microring-based SEs,we implement an 8×8 crossbar optical switch fabric.As the resonance wavelengths of all SEs are well aligned,only one SE needs to be turned on in each routing path,which greatly reduces the complexity of the switch control.The optical transmission spectra show a box-like shape,with a passband width of~69 GHz and an average on-state loss of~0.37 dB.The chip has a record-low on-chip insertion loss of 0.52-2.66 dB.We also implement a non-duplicate polarization-diversity optical switch by using the bidirectional transmission characteristics of the crossbar architecture,which is highly favorable for practical applications.100 Gb/s dual-polarization quadrature-phase-shift-keying(DP-QPSK)signal is transmitted through the switch without significant degradation.To the best of our knowledge,this is the first time that 3D MRRs have been used to build highly scalable polarization-diversity optical switch fabrics. | XIN LI WEI GAO LIANGJUN LU JIANPING CHEN LINJIE ZHOU | 2023 | Photonics Research2023，11，5： | 0 |
| 12 | Erratum to:Membrane fusion reverse micelle platforms as potential oral nanocarriers for efficient internalization of free hydrophilic peptides显示文摘Erratum to Nano Research 2023,16(7):9768-9780 http://gffzzd3cc09b8251d45dfs0b66bp0cqcfw69qb.ffgz.tsg.suse.edu.cn/10.1007/s12274-023-5645-7 The complete affiliations of co-author Yiying Lu is Institute of Pharmaceutics,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China and Department of Pharmacy,Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310058,China. | Mengting Lin Linjie Wu Yiying Lu Xiaoyan Bao Haiqing Zhong Qi Dai Qiyao Yang Yiyi Xia Xin Tan Yaxin Qin Ruolin Jiang Min Han | 2023 | Nano Research2023，16，7： | 0 |
| 13 | Self-Assembled Porous-Reinforcement Microstructure-Based Flexible Triboelectric Patch for Remote Healthcare显示文摘Realizing real-time monitoring of physiological signals is vital for preventing and treating chronic diseases in elderly individuals. However,wearable sensors with low power consumption and high sensitivity to both weak physiological signals and large mechanical stimuli remain challenges.Here, a flexible triboelectric patch(FTEP) based on porous-reinforcement microstructures for remote health monitoring has been reported. The porousreinforcement microstructure is constructed by the self-assembly of silicone rubber adhering to the porous framework of the PU sponge. The mechanical properties of the FTEP can be regulated by the concentrations of silicone rubber dilution. For pressure sensing, its sensitivity can be effectively improved fivefold compared to the device with a solid dielectric layer, reaching 5.93 kPa^(-1) under a pressure range of 0–5 kPa. In addition, the FTEP has a wide detection range up to 50 kPa with a sensitivity of 0.21 kPa^(-1). The porous microstructure makes the FTEP ultra-sensitive to external pressure, and the reinforcements endow the device with a greater deformation limit in a wide detection range. Finally, a novel concept of the wearable Internet of Healthcare(Io H) system for real-time physiological signal monitoring has been proposed, which could provide real-time physiological information for ambulatory personalized healthcare monitoring. | Hao Lei Haifeng Ji Xiaohan Liu Bohan Lu Linjie Xie Eng Gee Lim Xin Tu Yina Liu Peixuan Zhang Chun Zhao Xuhui Sun Zhen Wen | 2023 | Nano-Micro Letters2023，15，7： | 0 |
| 14 | Optical generation of UWB pulses utilizing Fano resonance modulation显示文摘In this paper,we reported an integrated method to generate ultra-wideband(UWB)pulses of different orders based on a reconfigurable silicon micro-ring resonator-coupled Mach–Zehnder interferometer.Under proper operating conditions,the device can produce Fano resonances with a peak-to-valley extinction ratio of above 20 dB.UWB monocycle and doublet signals with picosecond pulse widths are produced when the microring resonator is modulated by square and Gaussian electrical pulses,respectively.With our Fano resonance modulator on silicon photonics,it is promising to foresee versatile on-chip microwave signal generation. | Zhe XU Yanyang ZHOU Shuhuang CHEN Liangjun LU Gangqiang ZHOU Jianping CHEN Linjie ZHOU | 2021 | Frontiers of Optoelectronics2021，14，4： | 0 |
| 15 | Few-layered hexagonal boron nitride nanosheets stabilized Pt NPs for oxidation promoted adsorptive desulfurization of fuel oil显示文摘A few-layered hexagonal boron nitride nanosheets stabilized platinum nanoparticles(Pt/h-BNNS)is engineered for oxidation-promoted adsorptive desulfurization(OPADS)of fuel oil.It was found that the few-layered structure and the defective sites of h-BNNS not only are beneficial to the stabilization of Pt NPs but also favor the adsorption of aromatic sulfides.By employing Pt/h-BNNS with a Pt loading amount of 1.19 wt%as the active adsorbent and air as an oxidant,a 98.0%sulfur removal over dibenzothiophene(DBT)is achieved along with a total conversion of the DBT to the corresponding sulfones(DBTO_(2)).Detailed experiments show that the excellent desulfurization activity originates from the few-layered structure of h-BNNS and the high catalytic activity of Pt NPs.In addition,the OPADS system with Pt/h-BNNS as the active adsorbent shows remarkable stability in desulfurization performance with the existence of different interferents such as olefin,and aromatic hydrocarbons.Besides,the Pt/h-BNNS can be recycled 12 times without a significant decrease in desulfurization performance.Also,a process flow diagram is proposed for deep desulfurization of fuel oil and recovery of high value-added products,which would promote the industrial application of such OPADS strategy. | Peiwen Wu Xin Song Linlin Chen Lianwen He Yingcheng Wu Duanjian Tao Jing He Chang Deng Linjie Lu Yanhong Chao Mingqing Hua Wenshuai Zhu | 2024 | Green Energy & Environment2024，9，3： | 0 |
| 16 | Engineering 3D-printed aqueous colloidal ceramic slurry for direct ink writing显示文摘The construction of rapid prototyping for structured ceramics has a promoting effect on potential applications.In this work,engineering slurry with different formulations were used to develop aqueous colloidal ceramic slurry for direct ink writing(DIW).Optimized slurry of Formulation 5 possessed good printing effect for DIW with stable mechanical properties.Related characteristics,including shrinkage,compressive strength,rheological behavior,and chemical property,were also examined.DIW ceramics prepared from optimized slurry can be preliminarily applied to adsorption of Rhodamine B and chlortetracycline,and possessed the advantages of easy separation and operation compared with powder adsorbents.This work provides a strategy for the design of 3D-printed kaolin ceramic slurry,and also extends to potential application in adsorption. | Jie Zhu Jiangtao Yu Yingcheng Wu Yanhong Chao Peiwen Wu Linjie Lu Linlin Chen Jing He Wenshuai Zhu | 2023 | Green Chemical Engineering2023，4，1： | 0 |
| 17 | Experimental study on sand production and coupling response of silty hydrate reservoir with different contents of fine clay during depressurization显示文摘To further understand the characteristics of clay and sand production(hereafter collectively referred to as sand production)and to provide optimization designs of sand control schemes are critical for gas production from clayey silt natural gas hydrate reservoirs in the South China Sea.Thus,gas-water-sand production behavoirs and coupling reservoir subsidence characteristics before,during,and after hydrate dissociation of the clayey silt hydrate reservoirs with different clay contents(5%,10%,15%,20%,25%,and 30%)have been studied through a self-developed experimental system.The results show that with the increase of clay content,the total mass of sand production first increases and then decreases,and it reaches maximum when the clayey content is 20%.The sand production is the lowest before hydrate dissociation and increases significantly during hydrate dissociation,which mainly occurs in the high-speed gas and water production stage at the beginning of hydrate dissociation.After hydrate dissociation,the sand production decreases significantly.During the whole depressurization process,the clay and free sand particles generally move to the sand outlet due to the fluid driving force and overlying stress extrusion.However,for conditions of high clay contents,those particles fail to pass through the sand control screen and gradually accumulate and block the screen by forming a mud cake,which greatly reduce the permeability of the screen and limite sand production as well as gas and water production.Our research lays a foundation for sand production prediction and sand control scheme selection during gas recovery from clayey silty hydrate reservoirs that greatly need to consider a balance between sand control and gas productivity. | Xiangyu Fang Dianheng Yang Fulong Ning Linjie Wang Zhichao Liu Yanjiang Yu Wenwei Xie Hongfeng Lu Yanlong Li Meng Xu | 2023 | Petroleum2023，9，1： | 0 |
| 18 | Stable Au nanoparticles confined in boron nitride shells for optimizing oxidative desulfurization显示文摘Supported gold(Au)nanocatalysts have long played an important role in numerous heterogeneous catalysis.However,the dominant difficulty of poor thermodynamic stability hampers its practical application.Herein,a core–shell structured Au nanocatalyst with Au nanoparticles(NPs)confined in boron nitride(BN)shells is proposed for enhanced thermodynamic stability.The two-dimensional porous structure of BN not only functions as a physical separator for the sintering resistance of Au NPs,but also provides a microchannel for catalytic reaction substrates.Besides,owing to the confinement effect,a strengthened interaction between well-designed Au NPs and the BN can be expected,which further boosts the stability and catalytic activity.Detailed experiments show that a proper BN shell thickness is important to maintain the balance between the sintering resistance and catalytic activity.A significantly boosted performance of 97.2%conversion in oxidative desulfurization(ODS)was obtained with a proper number of BN coating layers,outperforming the one with a thicker BN shell.Moreover,the recyclability of the prepared catalyst was investigated with no obvious decrease in catalytic performance after 10 runs,greatly higher than that without a BN shell,suggesting excellent durability. | Linjie Lu Jing He Peiwen Wu Yang Sun Mingqing Hua Peng Cui Wenshuai Zhu Huaming Li Zhichang Liu Chunming Xu | 2023 | Nano Research2023，16，10： | 0 |
| 19 | Engineering the electronic and geometric structure of VO_(x)/BN@TiO_(2)heterostructure for efficient aerobic oxidative desulfurization显示文摘Particle size governs the electronic and geometric structure of metal nanoparticles(NPs),shaping their catalytic performances in heterogeneous catalysis.However,precisely controlling the size of active metal NPs and thereafter their catalytic activities remain an affordable challenge in ultra-deep oxidative desulfurization(ODS)field.Herein,a series of highly-efficient VO_(x)/boron nitride nanosheets(BNNS)@TiO_(2)heterostructures,therein,cetyltrimethylammonium bromide cationic surfactants serving as intercalation agent,BNNS and MXene as precursors,with various VO_(x)NP sizes were designed and controllably constructed by a facile intercalation confinement strategy.The properties and structures of the prepared catalysts were systematically characterized by different technical methods,and their catalytic activities were investigated for aerobic ODS of dibenzothiophene(DBT).The results show that the size of VO_(x)NPs and V^(5+)/V^(4+)play decisive roles in the catalytic aerobic ODS of VO_(x)/BNNS@TiO_(2)catalysts and that VO_(x)/BNNS@TiO_(2)-2 exhibits the highest ODS activity with 93.7%DBT conversion within 60 min under the reaction temperature of 130℃and oxygen flow rate of 200 mL·min-1,which is due to its optimal VO_(x)dispersion,excellent reducibility and abundant active species.Therefore,the finding here may contribute to the fundamental understanding of structure-activity in ultradeep ODS and inspire the advancement of highly-efficient catalyst. | Lu Zhang Jixing Liu Deqi Huang Wenfeng Zhang Linjie Lu Mingqing Hua Hui Liu Huifang Cheng Huaming Li Wenshuai Zhu | 2023 | Frontiers of Chemical Science and Engineering2023，17，3： | 0 |
| 20 | Membrane fusion reverse micelle platforms as potential oral nanocarriers for efficient internalization of free hydrophilic peptides显示文摘Orally administered peptides or proteins are garnering increasing preference owing to their superiority in terms of patient compliance and convenience.However,the development of oral protein formulations has stalled due to the low bioavailability of macromolecules that encounter the aggressive gastrointestinal environment and harsh mucus villi barrier.Herein,we propose an ideal reverse micelle/self-emulsifying drug delivery system(RM/SEDDS)nanoplatform that is capable of improving the oral bioavailability of hydrophilic peptides by preventing enzymatic degradation and enhancing mucosal permeability.Upon the passage through the mucus,the self-emulsifying drug delivery system with optimal surface properties effectively penetrates the viscoelastic mucosal barrier,followed by the exposure of the inner reverse micelle amphipathic vectors,which autonomously form continua with the lipidic cell membrane and facilitate the internalization of drugs.This membrane-fusion mechanism inaugurates a new way for hydrophilic peptide delivery in the free form,circumventing the traditional impediments of the cellular internalization of nanocarriers and subsequent poor release of drugs.And more importantly,reverse micelles are not spatially specific to the laden drugs,which enables their delivery for a myriad of peptide clinical drugs.In conclusion,as an exquisitely designed nanoplatform,RM/SEDDS overcomes multiple physiological barriers and opens a new path for drug cellular entry,providing new prospects for the development of oral drug delivery systems. | Mengting Lin Linjie Wu Yiying Lu Xiaoyan Bao Haiqing Zhong Qi Dai Qiyao Yang Yiyi Xia Xin Tan Yaxin Qin Ruolin Jiang Min Han | 2023 | Nano Research2023，16，7： | 0 |
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