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3篇 您的检索式:作者名="Linqi Shao"
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1Biomedical polymers: synthesis, properties, and applications显示文摘Biomedical polymers have been extensively developed for promising applications in a lot of biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis, biosensing, regenerative medicine, and disease treatment. In this review, we summarize the most recent advances in the synthesis and application of biomedical polymers, and discuss the comprehensive understanding of their property-function relationship for corresponding biomedical applications. In particular, a few burgeoning bioactive polymers, such as peptide/biomembrane/microorganism/cell-based biomedical polymers, are also introduced and highlighted as the emerging biomaterials for cancer precision therapy. Furthermore, the foreseeable challenges and outlook of the development of more efficient, healthier and safer biomedical polymers are discussed. We wish this systemic and comprehensive review on highlighting frontier progress of biomedical polymers could inspire and promote new breakthrough in fundamental research and clinical translation.Wei-Hai Chen Qi-Wen Chen Qian Chen Chunyan Cui Shun Duan Yongyuan Kang Yang Liu Yun Liu Wali Muhammad Shiqun Shao Chengqiang Tang Jinqiang Wang Lei Wang Meng-Hua Xiong Lichen Yin Kuo Zhang Zhanzhan Zhang Xu Zhen Jun Feng Changyou Gao Zhen Gu Chaoliang He Jian Ji Xiqun Jiang Wenguang Liu Zhuang Liu Huisheng Peng Youqing Shen Linqi Shi Xuemei Sun Hao Wang Jun Wang Haihua Xiao Fu-Jian Xu Zhiyuan Zhong Xian-Zheng Zhang Xuesi Chen 2022Science China Chemistry2022,65,6:2
2Tailoring spin mixtures by ion-enhanced Maxwell magnetic coupling in colortunable organic electroluminescent devices显示文摘In this work,we show that the spin dynamics of excitons can be dramatically altered by Maxwell magnetic field coupling,together with an ion-enhanced,low-internal-splitting-energy organic semiconducting emitter.By employing a unique,alternating current(AC)-driven organic electroluminescent(OEL)device architecture that optimizes this magnetic field coupling,almost complete control over the singlet-to-triplet ratio(from fluorescent to phosphorescent emission in a single device)is realized.We attribute this spin population control to magnetically sensitive polaron–spin pair intersystem crossings(ISCs)that can be directly manipulated through external driving conditions.As an illustration of the utility of this approach to spin-tailoring,we demonstrate a simple hybrid(double-layer)fluorescence–phosphorescence(F–P)device using a polyfluorene-based emitter with a strong external Zeeman effect and ion-induced long carrier diffusion.Remarkable control over de-excitation pathways is achieved by controlling the device-driving frequency,resulting in complete emission blue–red color tunability.Picosecond photoluminescence(PL)spectroscopy directly confirms that this color control derives from the magnetic manipulation of the singlet-totriplet ratios.These results may pave the way to far more exotic organic devices with magnetic-field-coupled organic systems that are poised to usher in an era of dynamic spintronics at room temperature.Junwei Xu Yue Cui Gregory M.Smith Peiyun Li Chaochao Dun Linqi Shao Yang Guo Hongzhi Wang Yonghua Chen David L.Carroll 2018Light(Science & Applications)2018,7,1:2
3Structural insights into the SARS-CoV-2 Omicron RBD-ACE2 interaction显示文摘Dear Editor,The global fight against the COVID-19 pandemic is still in great uncertainty due to the emergence of SARS-CoV-2 variants,especially the variants of concern(VOCs)with changed pathogenicity,increased transmissibility and the resistance to convalescent/vaccination sera and monoclonal neutralizing antibodies.1,2 As a newly reported VOC,the Omicron variant has caused great concern with 32 mutations in the spike glycoprotein including unprecedented 15 mutations in the receptor-binding domain(RBD),which would have significant impact on the viral infectivity and the protection effects of approved vaccines and therapeutic antibodies.3,4 A detailed description of the Omicron spike and its interactions with ACE2 receptor and neutralizing antibodies is essential for fully understanding the infection and immune escape of the Omicron variant at the molecular level.Jun Lan Xinheng He Yifei Ren Ziyi Wang Huan Zhou Shilong Fan Chenyou Zhu Dongsheng Liu Bin Shao Tie-Yan Liu Qisheng Wang Linqi Zhang Jiwan Ge Tong Wang Xinquan Wang 2022Cell Research2022,32,6:0
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