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3篇 您的检索式:作者名="Linxiao Fan"
    题名 作者 年代 出处 被引量
1Performance analysis of pattern classifier combination by plurality voting 显示文摘LinXiao fan Yacoub S Bums J 2003Pattern Recognition Letters2003,24,12:1
2Angle-selective perfect absorption with two-dimensional materials显示文摘Two-dimensional(2D)materials have great potential in photonic and optoelectronic devices.However,the relatively weak light absorption in 2D materials hinders their application in practical devices.Here,we propose a general approach to achieve angleselective perfect light absorption in 2D materials.As a demonstration of the concept,we experimentally show giant light absorption by placing large-area single-layer graphene on a structure consisting of a chalcogenide layer atop a mirror and achieving a total absorption of 77.6%in the mid-infrared wavelength range(~13μm),where the graphene contributes a record-high 47.2%absorptivity of mid-infrared light.Construction of such an angle-selective thin optical element is important for solar and thermal energy harvesting,photo-detection and sensing applications.Our study points to a new opportunity to combine 2D materials with photonic structures to enable novel device applications.Linxiao Zhu Fengyuan Liu Hongtao Lin Juejun Hu Zongfu Yu Xinran Wang Shanhui Fan 2015Light(Science & Applications)2015,4,1:0
3Temporal Integrative Omics Reveals an Increase in Nondegradative Ubiquitylation during Primary Hepatocyte Dedifferentiation显示文摘Primary hepatocytes(PHCs)are widely used in various fields,but the progressive deterioration of liverspecific features in vitro significantly limits their application.While the transcriptional regulation and whole cell proteome(WCP)of PHCs have been extensively studied,only a small number of studies have addressed the role of posttranslational modifications in this process.To elucidate the underlying mechanisms that induce dedifferentiation,we carried out parallel quantifications of the transcriptome,WCP,ubiquitinome,and phosphoproteome of rat PHCs after 0,6,12,24,and 48 h of in vitro culture.Our data constitute a detailed proteomic analysis of dedifferentiated PHCs including 2196 proteins,2056 ubiquitinated sites,and 4932 phosphorylated peptides.We revealed a low correlation between the transcriptome and WCP during dedifferentiation.A combined analysis of the ubiquitinome with the corresponding WCP indicated that the dedifferentiation of PHCs led to an increase in nondegradative K27 ubiquitination.Functional analysis of the altered phosphoproteins suggested a significant enrichment in ferroptosis.In all,404 proteins with both ubiquitination and phosphorylation were identified to be involved in critical metabolic events.Furthermore,Ptbph Hnqjd,Hnrnpu,and Srrm2 were identified as hub genes.Taken together,our data provide new insights into proteome dynamics during PHC dedifferentiation and potential targets to inhibit the dedifferentiation process.Zhengyi Jiang Zeyu Sun Xiaoxi Ouyang Yalei Zhao Menghao Zhou Baohong Wang Qirui Li Linxiao Fan Sainan Zhang Lanjuan Li 2020Engineering2020,6,11:0
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