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| 1 | Transcriptional Activation and Production of Tryptophan-Derived Secondary Metabolites in Arabidopsis Roots Contributes to the Defense against the Fungal Vascular Pathogen Verticillium Iongisporum显示文摘忍受土壤的真菌的病原体 Verticillium longisporum 在象 oilseed 强奸那样的 Brassicaceae 主人植物上引起脉管的疾病。真菌开拓殖民地于根木部并且向上搬到疾病症状变得可见的叶子。为早基因正式就职把 Arabidopsis 用作一个模型,我们分别地在孢子萌芽以后并且在根外皮的穿入期间立即响应菌丝的生长执行了根 transcriptome 分析。感染的根显示出象抄写因素的激活那样的基因表示的快速的 reprogramming,应力 -- ,并且防卫相关的基因。这里,我们集中了于导致导出色氨酸的第二等的代谢物的生产的高度协调的基因正式就职。在叶子的以前的研究证明 CYP81F2 和 PEN2 (PENETRATION2 ) 编码的酶执行抗真菌的吲哚 glucosinolate (IGS ) 的形成代谢物。在感染 Verticillium 的根,我们发现 transcriptional CYP81F2 和 PEN2 的激活相当或相同的事物 PEL1 (PEN2-LIKE1 ) ,而是抗真菌的 IGS 故障产品的没有增加。相反, indole-3-carboxylic 酸(I3CA ) 和 phytoalexin camalexin 在感染的根积累了,但是仅仅 camalexin 在 vitro 禁止了 Verticillium 生长。而导致 camalexin 或 CYP81F2 依赖的 IGS 代谢物的单个新陈代谢的小径的基因混乱没改变导致 Verticillium 的疾病症状, cyp79b2 cyp79b3 异种在两个分支损害了导致了显著地提高的危险性。因此,我们的数据提供卓见进根特定的早防卫并且对脉管的病原体作为活跃抗真菌的混合物建议导出色氨酸的代谢物。 | Tim Iven Stefanie Konig Seema Singh Susanna A. Braus-Stromeyer Matthias Bischoff Lutz F. Tietze Gerhard H. Braus Volker Lipka Ivo Feussner Wolfgang Droge-Laser | 2012 | Molecular Plant2012，5，6： | 4 |
| 2 | Substrate-decoupled,bulk-acoustic wave gyroscopes:Design and evaluation of next-generation environmentally robust devices显示文摘This paper reports on a new type of high-frequency mode-matched gyroscope with significantly reduced dependencies on environmental stimuli such as temperature,vibration,and shock.A novel stress-isolation system is used to effectively decouple an axis-symmetric bulk-acoustic wave(BAW)vibratory gyro from its substrate,minimizing the effect that external sources of error have on the offset and scale factor of the device.Substrate-decoupled(SD)BAW gyros with a resonance frequency of 4.3 MHz and Q values near 60000 were implemented using the high aspect ratio poly and single-crystal silicon(HARPSS)process to achieve ultra-narrow capacitive gaps.Wafer-level packaged sensors were interfaced with a customized application-specific integrated circuit(ASIC)to achieve low variations in the offset across temperature(±26°s^(−1) from−40 to 85℃),supreme random-vibration immunity(0.012°s^(−1) gRMS−1)and excellent shock rejection.With a scale factor of 800μV(°s^(−1))^(−1),the SD-BAW gyro system attains a large full-scale range(±1250°s^(−1))with a non-linearity of less than 0.07%.A measured angle-random walk(ARW)of 0.39°/√h and a bias instability of 10.5°h^(−1) are dominated by the thermal and flicker noise of the integrated circuit(IC),respectively.Additional measurements using external electronics show bias-instability values as low as 3.5°h−1,which are limited by feed-through signals coupled from the drive loop to the sense channel,which can be further reduced through proper re-routing of the gyroscope pin-out configuration. | Diego E.Serrano Mohammad F.Zaman Amir Rahafrooz Peter Hrudey Ron Lipka Duane Younkin Shin Nagpal Ijaz Jafri Farrokh Ayazi | 2016 | Microsystems & Nanoengineering2016，2，1： | 3 |
| 3 | Enantioseparation of ben- zoxazolinone aminoalcohols and their aminoketone precur- sors, potential adrenergic ligands, by analytical and prepara- tive liquid chromatography on amylose chiral stationary phases and characterization of the enantiomers 显示文摘 | Lipka E Vaccher C Bonte J P | 2009 | Chirality2009，21，8： | 1 |
| 4 | The value of knee arthroscopy in patients with severe radiological osteoarthritis显示文摘 | Bohnsack M Lipka W Rühmann O | | 0，，08： | 1 |
| 5 | Biomaehanical study of C1-C2 posterior arthrodesis显示文摘 | Hajek PD Lipka J Hartline P | 1993 | spine1993，18，2： | 1 |
| 6 | Enantioseparation of four cis and trans diastereomers of 2'3-didehydro-2'3-dideoxythymidine analogues by high-performance liquid chromatography and capillary electrophoresis显示文摘 | Lipka L Selouane A Postel D | 2004 | J Chromatogr A2004，1034，12： | 1 |
| 7 | Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption显示文摘 | Yu LX Lipka E Crison JR | 1996 | Adv Drug Deliv Rev1996，19，3： | 1 |
| 8 | Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor显示文摘 | Lipka LJ | 2003 | Cardiovasc Drug Rev2003，21，4： | 1 |
| 9 | 精神药物所致的癫痫发作与猝死显示文摘 | Lipka IJ 李焕德 朱运贵 | 1988 | 国外医学精神病学分册1988，，03： | 1 |
| 10 | An Arabidopsis callose synthase, GSL, is required for wound and papillary callose formation 显示文摘 | Jacobs A K Lipka V Burton R A | 2003 | Plant cell2003，15，： | 1 |
| 11 | Transport approaches to the biopharmaceutical design of oral drug delivery systems : prediction of intestinal absorption 显示文摘 | Yu L X Lipka E Crison J R | 1996 | Adv Drug Deliv Rev1996，19，3： | 1 |
| 12 | Transport approaches to the biopharmaceutical design of oral drug deli,Jery systems: Prediction of intestinal absorption显示文摘 | Yu LX Lipka E Crison J R | 2006 | Adv Drug Deliv Rev2006，19，3： | 1 |
| 13 | Bionmechanical study of C1-C2posterior arthrodesis techniques 显示文摘 | Hajed PD Lipka J Hartline P | 1993 | Spine1993，18，2： | 1 |
| 14 | Lessons from Dwarf8 on the strengths and weaknesses of structured association mapping显示文摘 | Larsson S J Lipka A E Buckler E S | 2013 | PLoS Genetics2013，9，10： | 1 |
| 15 | The literate brain:The relationship between spelling and reading显示文摘 | Rapp B Lipka K | | 0，，05： | 1 |
| 16 | An Arabidopsiscallose synthase, GSL5,is required for wound andpapillary callose formation 显示文摘 | Jacobs A K Lipka V Burton R A | 2003 | Plant Cell2003，15，： | 1 |
| 17 | Biomechanical study of C1-C2 posterior arthrodesis techniques显示文摘 | Hajek PK Lipka J Hartline P | 1993 | Spine1993，18，2： | 1 |
| 18 | The role of 2,3 DPG in nerve conduction in children with type 1 diabetes显示文摘 | SzypowskaMarta Ewa PańkowskaAgnieszka WysockaMaria Lipka | 2009 | 2009，，41： | 1 |
| 19 | No Evidence for Efficacy of Radiofrequency Ablation for Treatment of Gastroesophageal Reflux Disease: A Systematic Review and Meta-analysis显示文摘 | Seth Lipka Ambuj Kumar Joel E. Richter | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 1 |
| 20 | Basal insulin and total daily insulin dose in children with type 1 diabetes using insulin pumps显示文摘 | Pankowska E Szypowska A Lipka M | 2008 | Pediatr Diabetes2008，9，31： | 1 |
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