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| 1 | The Hardy Rubber Tree Genome Provides Insights into the Evolution of Polyisoprene Biosynthesis显示文摘Eucommia ulmoides,也叫的强壮的橡胶树,是一棵经济地重要的树;然而,它的染色体顺序的缺乏 ?限制基本生物研究和这植物种的应用研究。这里,我们在场它的 1.2-Gb 染色体的一个高质量的集会(支架 N50 ?=? 1.88 Mb ) 与至少 26 ? 为 E 的 723 预言的基因。ulmoides,顺序 Garryales 的首先定序的染色体,它用联合定序的 Illumina 的综合策略被获得,定序的 PacBio,和印射的 BioNano。作为到 lamiids 和 campanulids 的姐妹 taxon, E。ulmoides 经历了三倍由核心 eudicots 而是没有进一步整个染色体的复制分享了的一个古老的染色体 ? 在最后 1.25 亿年里。E。ulmoides 为涉及压力回答和第二等的代谢物的生合成的多重基因展出高表达式层次或基因数字扩大,它可以说明它的可观的环境适应性。与橡胶树(Hevea brasiliensis ) 相对照,它生产 cis 聚异式戊二我烯, E。ulmoides 演变综合经由 farnesyl diphosphate synthases (FPS ) 的长链的 trans 聚异式戊二我烯。而且, FPS 和橡胶延伸 factor/small 橡胶粒子蛋白质基因家庭从 H 独立地被扩展。brasiliensis 系。这些结果提供新卓见进 E. 的生物学 ? ulmoides 和聚异式戊二我烯生合成的起源。 | Ta-na Wuyun Lin Wang Huimin Liu Xuewen Wang Liangsheng Zhang Jeffrey L. Bennetzen Tiezhu Li Lirong Yang Panfeng Liu Lanying Du Lu Wang Mengzhen Huang Jun Qing Iili Zhu Wenquan Bao Hongguo Li Qingxin Du Jingle Zhu Hong Yang Shuguang Yang Hui Liu Hui Yue Jiang Hu Suoliang Yu Yu Tian Fan Liang Jingjing Hu Depeng Wang Ruiwen Gao Dejun Li Hongyan Du | 2018 | Molecular Plant2018，11，3： | 24 |
| 2 | Markov repairable systems with stochastic regimes switching显示文摘Compared with the classical Markov repairable system,the Markov repairable system with stochastic regimes switching introduced in the paper provides a more realistic description of the practical system.The system can be used to model the dynamics of a repairable system whose performance regimes switch according to the external conditions.For example,to satisfy the demand variation that is typical for the power and communication systems and reduce the cost,these systems usually adjust their operating regimes.The transition rate matrices under distinct operating regimes are assumed to be different and the sojourn times in distinct regimes are governed by a finite state Markov chain.By using the theory of Markov process,Ion channel theory,and Laplace transforms,the up time of the system are studied.A numerical example is given to illustrate the obtained results.The effect of sojourn times in distinct regimes on the availability and the up time are also discussed in the numerical example. | Liying Wang Lirong Cui Mingli Yu | 2011 | Journal of Systems Engineering and Electronics2011，22，5： | 5 |
| 3 | Fabricating Pd isolated single atom sites on C3N4/rGO for heterogenization of homogeneous catalysis显示文摘Metal isolated single atomic sites catalysts have attracted intensive attention in recent years owing to their maximized atom utilization and unique structure.Despite the success of single atom catalyst synthesis,directly anchoring metal single atoms on three-dimensional(3D)macro support,which is promising to achieve the heterogenization of homogeneous catalysis,remains a challenge and a blank in this field.Herein,we successfully fabricate metal single atoms(Pd,Pt,Ru,Au)on porous carbon nitride/reduced graphene oxide(C3N4/rGO)foam as highly efficient catalysts with convenient recyclability.C3N4/rGO foam features two-dimensional microstructures with abundant N chelating sites for the stabilization of metal single atoms and vertically-aligned hierarchical mesostructure that benefits the mass diffusion.The obtained Pdi/C3N4/rGO monolith catalyst exhibits much enhanced activity over its nanoparticle counterpart for Suzuki-Miyaura reaction.Moreover,the Pdi/C3N4/rGO monolith catalyst can be readily assembled in a flow reactor to achieve the highly efficient continuous production of 4-nitro-1,1'-biphenyl through Suzuki-Miyaura coupling. | Ninghua Fu Xiao Liang Zhi Li Wenxing Chen Yu Wang Lirong Zheng Qinghua Zhang Chen Chen Dingsheng Wang Qing Peng Lin Gu Yadong Li | 2020 | Nano Research2020，13，4： | 5 |
| 4 | Protective effects of MCI-186 on oxidative damage in a cell model of Alzheimer's disease显示文摘Oxidative stress has an important role in the development of Alzheimer's disease (AD). Beta amyloid protein 25-35 (Aβ25-35) can generate oxygen free radicals, and MCI-186 (3-methyl-1-phenyl-2-pyrazolin-5-one, edaravone) can specifically eliminate hydroxyl radicals. The present study introduced Aβ25-35 into PC12 cells to establish a cell model of AD, and investigated the neuroprotective effects of MCI-186 on AD. Results showed that MCI-186 had a positive effect on the prevention and treatment of AD by inhibiting protein oxidative products, advanced glycation end products, lipid oxidative end products and DNA oxidative damage in PC12 cells induced by Aβ25-35. | Ming Yu Shujuan Li Wenhui Leng Han Chen Yingquan Wu Lirong Yan | 2010 | Neural Regeneration Research2010，5，16： | 5 |
| 5 | The soil configuration on granite residuals affects Benggang erosion by altering the soil water regime on the slope显示文摘A permanent collapsing gully,locally called Benggang,formed on slopes with deep granite red soil and is a type of unique gully erosion widely prevalent in southern China.Three different soil configurations(SC),ie,red-transition-sandy(SC I,the transition is the soil layer between the red soil and the sandy soil layer),transition-sandy(SC II)or sandy(SC III)are usually present in the soil profile of the Benggang slope.However,little attention has been paid to impacts of SCs on the triggering of Benggang erosion.In this study,we aimed to explore the relationships between soil water content(SWC)and triggering of Benggang erosion under different SC conditions.The soil properties of different soil layers were measured and the SWC at depths of 20,40,60,and 80 cm were monitored at 5-min intervals along a typical Benggang(SC I)during 2016-2018.The SWC of Benggang slopes with different SCs were simulated by VADOSE/W model.Results showed that the red soil layer had a higher water retention capacity and shear strength than the sandy soil layer.Even if the SWC is higher(e.g.,0.42 cm^(3)/cm^(3))at red soil layer or transition layer,the corresponding shear strength is greater than that of sandy soil layer with a lower SWC(e.g.,032 cm^(3)/cm^(3)).Relationships between shear strength and SWC of different soil layers indicate that Benggang erosion is triggered by an increase in the SWC in the deep sandy layer.Results also showed that differences exist in the SWC distribution among the different SCs.The SWC is higher in topsoil than in deeper soil in SC I and SC II,while in SC III,the opposite trend is observed.These results revealed that the presence of the red soil or transition layer can reduce the infiltration of rainwater into the deep sandy layer,thus can reduce the possibility of collapse.Our results show that the SC affects the stability of the headwall,and results provide great significances to guide the mitigation of Benggang erosion. | Xiaoqian Duan Yusong Deng Yu Tao Yangbo He Lirong Lin Jiazhou Chen | 2021 | International Soil and Water Conservation Research2021，9，3： | 4 |
| 6 | Influence of chronic intermittent hypoxia on growth associated protein 43 expression in the hippocampus of young rats显示文摘This study aimed to explore the pathological change to hippocampal neurons and the expression of growth associated protein 43 in 21-day-old young rats following chronic intermittent hypoxia.Hematoxylin-eosin staining results showed varying degrees of degeneration and necrosis in hippocampal neurons depending on the modeling time.Immunohistochemistry revealed that growth associated protein 43 expression in young rats following chronic intermittent hypoxia decreased,but that levels were still higher than those of normal rats at each time point,especially 4 weeks after modeling.During 1-5 weeks after modeling,a slow growth in rat weight was observed.Experimental findings indicate that chronic intermittent hypoxia may induce growth dysfunction and necrosis of hippocampal neurons,as well as increase the expression of growth associated protein 43 in young rats. | Yan Chen Chunling Zhao Chunlai Zhang Lirong Luo Guang Yu | 2012 | Neural Regeneration Research2012，7，16： | 4 |
| 7 | One-pot synthesis of MoSe2 hetero-dimensional hybrid self-assembled by nanodots and nanosheets for electrocatalytic hydrogen evolution and photothermal therapy显示文摘我们基于铝硒化物设计了并且准备一个异种维的混血儿(HDH )(MoSe 2) nanodots (ND ) 经由一个一个壶在很少层 MoSe 2 nanosheets (NS )(MoSe 2 HDH ) 抛锚了热水的过程。MoSe 2 HDH 向氢进化反应展出优秀 electrocatalytic 活动(她的) 。这是因为在一方面,在 MoSe 2 NSs/NDs 的接口的 MoSe 2 ND 和唯一的充满缺点的结构的边丰富的特征能为她引进更活跃的地点;在另一方面,在支持的电极的表面上像薄片的 MoSe 2 NS 叠的随机可以完成有效费用运输。另外, MoSe 2 HDH 显示出好水稳定性,理想的 biocompatibility,和高度近红外线(NIR ) photothermal 变换效率。因此, MoSe 2 HDH 为癌症在 NIR photothermal 治疗(PTT ) 作为 nanomedicine 被调查。明确地, MoSe 2 HDH 能为计算断层摄影术(CT ) 和 photoacoustic 断层摄影术(PA ) 作为一根双形式的探针被使用由于它的强壮的 X 光检查变细能力和 NIR 吸收的成像。因此, MoSe 2 HDH,有进一个系统的 CT/PA 成像的联合 PTT,为指导成像的癌症 theranostics 的抓住伟人潜力。这个工作可以提供机灵的策略准备另外的异种维的分层的转变金属 dichalcogenides。 | Baoguang Mao Tao Bao Jie Yu Lirong Zheng Jinwen Qin Wenyan Yin Minhua Cao | 2017 | Nano Research2017，10，8： | 3 |
| 8 | Phosphonate-Decorated Covalent Organic Frameworks for Actinide Extraction: A Breakthrough Under Highly Acidic Conditions显示文摘Although solid-phase extraction is a useful approach for metal ion separation from aqueous solutions,existing sorbents suffer from low extraction effici-encies and/or instability when in contact with strong acidic media.We report here the first study on rational design and fabrication of phosphonate-decorated covalent organic frameworks,COF-IHEP1 and COF-IHEP2,for efficient and selective extraction of of uranium(VI)[U(VI)]and plutonium(IV)[Pu(IV)]from highly acidic solutions. | Jipan Yu Liyong Yuan Shuai Wang Jianhui Lan Lirong Zheng Chao Xu Jing Chen Lin Wang Zhiwei Huang Wuqing Tao Zhirong Liu Zhifang Chai John K.Gibson Weiqun Shi | 2019 | CCS Chemistry2019，1，3： | 3 |
| 9 | Uniform single atomic Cu_(1)-C_(4)sites anchored in graphdiyne for hydroxylation of benzene to phenol显示文摘For single-atom catalysts(SACs),the catalyst supports are not only anchors for single atoms,but also modulators for geometric and electronic structures,which determine their catalytic performance.Selecting an appropriate support to prepare SACs with uniform coordination environments is critical for achieving optimal performance and clarifying the relationship between the structure and the property of SACs.Approaching such a goal is still a significant challenge.Taking advantage of the strong d-πinteraction between Cu atoms and diacetylenic in a graphdiyne(GDY)support,we present an efficient and simple strategy for fabricating Cu single atoms anchored on GDY(Cu_(1)/GDY)with uniform Cu_(1)-C_(4)single sites under mild conditions.The Cu atomic structure was confirmed by combining synchrotron radiation X-ray absorption spectroscopy,X-ray photoele ctron spectroscopy and density functional theory(DFT)calculations.The as-prepared Cu1/GDY exhibits much higher activity than state-of-the-art SACs in direct benzene oxidation to phenol with H_(2)O_(2)reaction,with turnover frequency values of 251 h^(-1)at room temperature and 1889 h^(-1)at 60℃,respectively.Furthermore,even with a high benzene conversion of86%,high phenol sele ctivity(96%)is maintaine d,which can be ascribed to the hydrophobic and oleophyllic surface nature of Cu1/GDY for benzene adsorption and phenol desorption.Both experiments and DFT calculations indicate that Cu_(1)-C_(4)single sites are more effective at activating H_(2)O_(2)to form Cu=O bonds,which are important active intermediates for benzene oxidation to phenol. | Jia Yu Changyan Cao Hongqiang Jin Weiming Chen Qikai Shen Peipei Li Lirong Zheng Feng He Weiguo Song Yuliang Li | 2022 | National Science Review2022，9，9： | 3 |
| 10 | Numerical investigation of airborne transmission of respiratory infections on the subway platform显示文摘Underground subway platforms are among the world’s busiest public transportation systems,but the airborne transmission mechanism of respiratory infections on these platforms has been rarely studied.Here,computational fluid dynamics(CFD)modeling is used to investigate the airflow patterns and infection risks in an island platform under two common ventilation modes:Mode 1-both sides have air inlets and outlets;Mode 2-air inlets are present at the two sides and outlets are present in the middle.Under the investigated scenario,airflow structure is characterized by the ventilation jet and human thermal plumes.Their interaction with the infector’s breathing jet imposes the front passenger under the highest exposure risk by short-range airborne route,with intake fractions up to 2.57%(oral breathing)or 0.63%(nasal breathing)under Mode 1;oral breathing of the infector may impose higher risks for the front passenger compared with nasal breathing.Pathogen are efficiently diluted as they travel further,in particular to adjacent crowds.The maximum and median value of intake fractions of passengers in adjacent crowds are respectively 0.093%and 0.016%(oral breathing),and 0.073%and 0.014%(nasal breathing)under Mode 1.Compared with Mode 1,the 2nd mode minimizes the interaction of ventilation jet and breathing jet,where the maximum intake fraction is only 0.34%,and the median value in the same crowd and other crowds are reduced by 23–63%.Combining published quanta generation rate data of COVID-19 and influenza infectors,the predicted maximum and median infection risks for passengers in the same crowds are respectively 1.46%–40.23%and 0.038%–1.67%during the 3–10 min waiting period,which are more sensitive to ventilation rate and exposure time compared with return air.This study can provide practical guidance for the prevention of respiratory infections in subway platforms. | Jianjian Wei Sirui Zhu Feiwu He Qianfang Guo Xinxin Huang Jianxiang Yu Lirong Zou Tao Jin Jie Wu | 2022 | Geoscience Frontiers2022，13，6： | 2 |
| 11 | Analysis on the Effects of Morphological Traits of Lutraria sieboldii on Its Body Mass Trait显示文摘[Objectives]This study was conducted to explore the relationship between morphological traits and body mass trait of Lutraria sieboldii.[Methods]110 were randomly selected from 120 2^(nd)-instar L.sieboldii collected from the Tieshangang area of Beihai,Guangxi,and 132 were randomly selected from 150 shellfish at the instar of 0.6.Their morphological traits were measured:shell length(SL),shell height(SH),shell width(SW),anterior length(AL),posterior length(PL),nose length(NL)in closed shell state,and maximum open shell width(OS)between two shells in closed shell state,and the body mass trait BM was also measured.Statistical methods such as path analysis and multiple regression were used for data analysis,and the effects of these seven morphological traits on the body mass trait were studied,respectively.The correlation between the tested seven quantitative traits and one body mass trait was all positive,all reaching an extremely significant level(P<0.01).[Results]The body mass trait of the shellfish at the instar of 2 had the highest correlation coefficient with shell length(0.922),that is,shell length had the greatest direct impact on the body mass trait;the path coefficient was 0.700;and the final multiple regression equation established was BM=-124.882+1.189 SL+1.551 SH+1.035 SW+0.119 NL,and the total determination coefficient(R^(2))on body mass was 0.849.The body mass trait of the shellfish at the instar of 0.6 had the highest correlation coefficient with shell length(0.859),that is,shell length had the greatest direct impact on the body mass trait;the path coefficient was 0.494;and the final multiple regression equation established was BM=-1.917+0.111 SL+0.021 NL+0.078 SW+0.032 OS,and the total determination coefficient(R~2)on body mass was 0.828.The multivariate regression variance analysis showed that the regression between the morphological traits and body mass trait of the L.sieboldii at the instars of 2 and 0.6 reached an extremely significant level(P<0.01).[Conclusions]This study provides a scientific basis for the selection of broodstock in the selection and breeding of L.sieboldii. | Dan GUO Jian CHEN Ziqin ZHAI Tongtong REN Jijin WANG Lirong BAI Dahui YU | 2021 | Agricultural Biotechnology2021，10，4： | 2 |
| 12 | Decomposing the influencing factors of industrial carbon emissions in Shanghai using the LMDI method显示文摘 | Min Zhao Lirong Tan Weiguo Zhang Minhe Ji Yuan Liu Lizhong Yu | 2010 | Energy2010，，6： | 2 |
| 13 | Identification of two-dimensional electrophoresis-separated proteins in human hepatoma cell by electrospray ion trap mass spectrometry显示文摘As one of the most important analytical methods in proteome research, mass spectrometry was utilized to identify proteins separated by two-dimensional electrophoresis in the human hepatoma cell line BEL-7404. The protein spots were excised from the gel, followed by in-gel digestion, and the peptide mappings were analyzed by liquid chromatography electrospray ion trap mass spectrometer. Nine proteins were identified via database searching, according to the molecular weights and amino acid sequences of peptides, among which two proteins have not been identified in the other liver-cell database. The sequence coverage was 21% -72%. Furthermore, the relationship between the expressed proteins and the liver carcinoma was discussed. | Rong Zeng Lirong Yu Xiaoxia Shao Qichang Xia | 2000 | Chinese Science Bulletin2000，45，16： | 2 |
| 14 | Insights into the phenomenon of an explosive growth and sharp decline in haze:A case study in Beijing显示文摘A severe haze episode occurred in winter in the North China Plain(NCP),and the phenomenon of an explosive growth and sharp decline in PM2.5(particulate matter with an aerodynamic diameter equal to or less than 2.5μm)concentration was observed.To study the systematic causes for this phenomenon,comprehensive observations were conducted in Beijing from November 26 to December 2,2015;during this period,meteorological parameters,LIDAR data,and the chemical compositions of aerosols were determined.The haze episode was characterized by rapidly varying PM2.5 concentration,and the highest PM2.5 concentration reached 667μg/m3.During the haze episode,the NCP was dominated by a weak high-pressure system and continuously low PBL(planetary boundary layer)heights,which are unfavorable conditions for the diffusion of pollutants.The large increases in the concentrations of SNA(SO42-,NO3-and NH4+)during the haze implied that the formation of SNA was the largest contribution.Water vapor also played a vital role in the formation of haze by promoting the chemical transformation of secondary pollutants,which led to higher PM2.5 concentrations.The spatial distributions of PM2.5 in Beijing at different times and the backward trajectories of the air masses also indicated that pollutants from surrounding provinces in particular,contributed to the higher PM2.5concentration. | Wenguang Li Xingang Liu Yuanhang Zhang Qinwen Tan Miao Feng Mengdi Song Lirong Hui Yu Qu Junling An Haokai Gao | 2019 | Journal of Environmental Sciences2019，31，10： | 1 |
| 15 | Hemoglobin on phos- phonic acid terminated self-assembled monolayers at a gold electrode: Immobilization, direct electrochemistry, and electrocatalysis显示文摘 | Chen Yu Jin Bo Guo Lirong | 2008 | Chem Eur J2008，14，10： | 1 |
| 16 | Direct electro- chemistry and electrocatalysis of hemoglobin at three dimen- sional gold film electrode modified with self-assembled mono- layers of 3kmercaptopropylphosphonic acid显示文摘 | Chen Yu Yang Xiaojing Guo Lirong | 2009 | Analytica Chimica Aeta2009，644，12： | 1 |
| 17 | Trainable unit selection speech synthesis under statistical framework显示文摘This paper proposes a trainable unit selection speech synthesis method based on statistical modeling framework. At training stage, acoustic features are extracted from the training database and statistical models are estimated for each feature. During synthesis, the optimal candidate unit sequence is searched out from the database following the maximum likelihood criterion derived from the trained models. Finally, the waveforms of the optimal candidate units are concatenated to produce synthetic speech. Experiment results show that this method can improve the automation of system construction and naturalness of synthetic speech effectively compared with the conventional unit selection synthe-sis method. Furthermore, this paper presents a minimum unit selection error model training criterion according to the characteristics of unit selection speech synthesis and adopts discriminative training for model parameter estimation. This criterion can finally achieve the full automation of system con-struction and improve the naturalness of synthetic speech further. | WANG RenHua DAI LiRong LING ZhenHua HU Yu | 2009 | Chinese Science Bulletin2009，54，11： | 1 |
| 18 | Increasing temperature anomalies reduce coral growth in the Weizhou Island, northern South China Sea显示文摘 | CHEN Tianran LIShu YU Kefu ZHENG Zhaoyong WANG Lirong CHEN Tegu | 2013 | Estuarine Coastal and Shelf Science2013，130，： | 1 |
| 19 | Genomic and transcriptomic analyses enable the identification of important genes associated with subcutaneous fat deposition in Holstein cows显示文摘Subcutaneous fat deposition has many important roles in dairy cattle,including immunological defense and mechanical protection.The main objectives of this study are to identify key candidate genes regulating subcutaneous fat deposition in high-producing dairy cows by integrating genomic and transcriptomic datasets.A total of 1654 genotyped Holstein cows are used to perform a genome-wide association study(GWAS)aiming to identify genes associated with subcutaneous fat deposition.Subsequently,weighted gene co-expression network analyses(WGCNA)are conducted based on RNA-sequencing data of 34 cows and cow yield deviations of subcutaneous fat deposition.Lastly,differentially expressed(DE)m RNA,lnc RNA,and differentially alternative splicing genes are obtained for 12 Holstein cows with extreme and divergent phenotypes for subcutaneous fat deposition.Forty-six protein-coding genes are identified as candidate genes regulating subcutaneous fat deposition in Holstein cattle based on GWAS.Eleven overlapping genes are identified based on the analyses of DE genes and WGCNA.Furthermore,the candidate genes identified based on GWAS,WGCNA,and analyses of DE genes are significantly enriched for pathways involved in metabolism,oxidative phosphorylation,thermogenesis,fatty acid degradation,and glycolysis/gluconeogenesis pathways.Integrating all findings,the NID2,STARD3,UFC1,DEDD,PPP1R1B,and USP21 genes are considered to be the most important candidate genes influencing subcutaneous fat deposition traits in Holstein cows.This study provides novel insights into the regulation mechanism underlying fat deposition in high-producing dairy cows,which will be useful when designing management and breeding strategies. | Hailiang Zhang Siyuan Mia Luiz F.Brito Lirong Hu Lei Wang Longgang Ma Qing Xu Gang Guo Ying Yu Yachun Wang | 2023 | Journal of Genetics and Genomics2023，50，6： | 1 |
| 20 | Two-dimensional gel electrophoresis analysis of the proteomes expressed in the human hepatoma cell line BEL-7404 and normal liver cell line L-02显示文摘Proteome analysis technology has been used extensively in conducting discovery research of biology and has become one of the most essential technologies in functional genomics. The proteomes of the human hepatoma cell line BEL-7404 and the normal human liver cell line L-02 have been separated by high resolution two-dimensional gel electrophoresis (2-DE) with immobilized pH gradient isoelectric focusing (IPG-IEF) in the first dimension and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) in the second dimension (IPG-DALT). The resulting images have been analyzed using 2-D analysis software. Quantitative analysis reveals that 7 protein spots are detected only in hepatoma BEL-7404 cells, 14 only in L-02 cells, and 78 protein spots show significant fluctuation in quantity in both cell lines (P<0.01). These protein spots have been displayed on a proteome differential expression map. Analysis for the reproducibility of 2-DE indicates that the positional variability in the IEF dimension | YU Lirong WANG Nan WU Gaode XU Yonghua XIA Qichang | 2000 | Chinese Science Bulletin2000，45，12： | 1 |
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