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3篇 您的检索式:作者名="Liu Yanghao"
    题名 作者 年代 出处 被引量
1Effect of suppressing dust by multi-direction whirling air curtain on fully mechanized mining face显示文摘A combined method of numerical simulation and field testing was adopted in this study in the interest of solving the problem of hard to control high concentrate dusts on a fully mechanized mining face.In addition,the dust suppression effect of a multi-direction whirling air curtain was studied in this paper.Under the influence of the wall attachment effect,the compressed air which blows out from the two-phase or three-phase radial outlets on the generator of the air curtain can form a multi-direction whirling air curtain,which can cover the whole roadway section of a fully mechanized mining face.The traditional method of controlling dust is a forcing system with exhaust overlap which has the major disadvantage of lacking a jet effect and consequently results in poor dust control.It is difficult to form the air flow field within the range of L_p5Sr^(1/2).However,due to the effect of this novel system,the radial airflow can be turned into axial airflow allowing fresh air to flow through the length of the heading.The air flow field which is good at controlling dust diffusion can be formed 12.8 m from the heading face.Furthermore,the field measurement results show that before the application of a multi-direction whirling air curtain,the dust concentration is 348.6 mg/m^3 and 271.4 mg/m^3 respectively at the roadway cross-section measurement points which are 5 m and 10 m from the heading face.However,after the application of the multi-direction whirling air curtain,the dust concentration is only 61.2 mg/m^3 and 14.8 mg/m^3,respectively.Therefore,the dust control effect of a multi-direction whirling air curtain is obvious.Nie Wen Liu Yanghao Wei Wenle Hu Xiangming Ma Xiao Peng Huitian 2016International Journal of Mining Science and Technology2016,26,4:6
2Recommender systems based on ranking performance optimization显示文摘Richong ZHANG Han BAO Hailong SUN Yanghao WANG Xudong LIU 2016Frontiers of Computer Science2016,10,2:1
3Engineering Komagataella phaffii to biosynthesize cordycepin from methanol which drives global metabolic alterations at the transcription level显示文摘Cordycepin has the potential to be an alternative to the disputed herbicide glyphosate.However,current laborious and time-consuming production strategies at low yields based on Cordyceps militaris lead to extremely high cost and restrict its application in the field of agriculture.In this study,Komagataella phaffii(syn.Pichia pastoris)was engineered to biosynthesize cordycepin from methanol,which could be converted from CO_(2).Combined with fermentation optimization,cordycepin content in broth reached as high as 2.68±0.04 g/L within 168 h,around 15.95 mg/(L⋅h)in productivity.Additionally,a deaminated product of cordycepin was identified at neutral or weakly alkaline starting pH during fermentation.Transcriptome analysis found the yeast producing cordycepin was experiencing severe inhibition in methanol assimilation and peroxisome biogenesis,responsible for delayed growth and decreased carbon flux to pentose phosphate pathway(PPP)which led to lack of precursor supply.Amino acid interconversion and disruption in RNA metabolism were also due to accumu-lation of cordycepin.The study provided a unique platform for the manufacture of cordycepin based on the emerging non-conventional yeast and gave practical strategies for further optimization of the microbial cell factory.Huiping Tan Liang Wang Huiguo Wang Yanghao Cheng Xiang Li Huihui Wan Chenguang Liu Tian Liu Qian Li 2023Synthetic and Systems Biotechnology2023,8,2:0
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