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| 1 | Human immune repertoire in hepatitis B virus infection显示文摘Hepatitis B virus(HBV)infection is a public health threat that affects 257 million people worldwide and can progress to liver cirrhosis,liver failure,and hepatocellular carcinoma.The HBV antigen-induced adaptive immune response plays an important role in HBV clearance.Immune repertoire sequencing(IRS)has been used to investigate the molecular mechanisms behind the immune system,find novel ways to treat HBV infection,and evaluate the genetic responses and immune characteristics of individuals infected by HBV or immunized by HBV vaccine.This review summarizes the human immune repertoire analysis methodology,and the application of the IRS in the prediction of HBV infection progression,treatment,and vaccination. | Qiao Zhan Jing-Hang Xu Yan-Yan Yu Emily Lo KK Felicianna Hani El-Nezami Zheng Zeng | 2021 | World Journal of Gastroenterology2021，27，25： | 4 |
| 2 | Outcome analysis of management of liver trauma: A 10-year experience at a trauma center显示文摘AIM: To review the outcomes of liver trauma in patients with hepatic injuries only and in patients with associated injuries outside the liver.METHODS: Data of liver trauma patients presented to our center from January 2003 to October 2013 were reviewed. The patients were divided into two groups. Group 1 consisted of patients who had hepatic injuries only. Group 2 consisted of patients who also had associated injuries outside the liver.RESULTS: Seven(30.4%) patients in group 1 and 10(28.6%) patients in group 2 received non-operative management; the rest underwent operation. Blunt trauma occurred in 82.8%(48/58) of the patients and penetrative trauma in 17.2%(10/58). A higher injury severity score(ISS) was observed in group 2(median 45 vs 25, P < 0.0001). More patients in group 1 were hemodynamically stable(65.2% vs 37.1%, P = 0.036). Other parameters were comparable between groups. Group 1 had better 30-d survival(91.3% vs 71.4%, P = 0.045). On multivariate analysis using the logistic regression model, ISS was found to be associated with mortality(P = 0.004, hazard ratio = 1.035, 95%CI:CONCLUSION: Liver trauma patients with multiple injuries are relatively unstable on presentation. Despite a higher ISS in group 2, non-operative management was possible for selected patients. Associated injuries outside the liver usually account for morbidity and mortality. | Wong Hoi She Tan To Cheung Wing Chiu Dai Simon HY Tsang Albert CY Chan Daniel KH Tong Gilberto KK Leung Chung Mau Lo | 2016 | World Journal of Hepatology2016，8，15： | 3 |
| 3 | Thyroarytenoid muscle activity associated with hypophonia in Parkinson disease and aging显示文摘 | Baker KK Ramig LO Luschei ES | 1998 | Neurology1998，51，： | 1 |
| 4 | Detecting exon deletions and duplications of the DMD gene using Multiplex Ligation-dependent Probe Amplification (MLPA) 显示文摘 | Lai KK Lo IF Tong TM | 2006 | Clin Biochem2006，39，4： | 1 |
| 5 | Intercellular adhesion molecule - 1 mediates murine colon adenocarcinoma invasion显示文摘 | Howard K Lo KK Ao L | 2014 | J Surg Res2014，187，1： | 1 |
| 6 | Retroperitoneal ancient schwannoma : review of clinico-radiological features 显示文摘 | Loke TK Yuen NW Lo KK | 1998 | Australas Radiol1998，42，2： | 1 |
| 7 | Survival analysis of patients withtransplantable recurrent hepatocellular carcinoma: implications forsalvage liver transplant显示文摘 | Ng KK Lo CM Liu CL | 2008 | Arch Surg2008，143，1： | 1 |
| 8 | Detecting exon deletions and duplications of the DMD gene using Multiplex Ligation -dependent Probe Amplification ( MLPA ) 显示文摘 | Lai KK Lo IF Tong TM | 2006 | Clin Biochem2006，39，4： | 1 |
| 9 | Linkage and association of myocilin (MYOC) polymorphisms with high myopia in a Chinese population显示文摘 | Tang WC Yip SP Lo KK | 2007 | Mol Vis2007，13，： | 1 |
| 10 | A First Reported Case of oculocerebrorenal syndrome of Lowe in Hong Kong and review ofliterature显示文摘 | Chan KK Lo IFM Cherk SWW eta | 2007 | HK J Paediatr (New Series)2007，12，： | 1 |
| 11 | Exclusion of candidate genes from a role in cleft lip with or without cleft palate显示文摘 | Vintiner GM Lo KK Holder SE | 1993 | J Med Genet1993，30，9： | 1 |
| 12 | Mycosis fungoides-a retrospective study of 40 cases in Hong Kong显示文摘 | Ku LS Lo KK | 2005 | Int J Dermatol2005，44，3： | 1 |
| 13 | Prevalence of obesity and trends in body mass index among US children and adoles- cents, 1999-2010显示文摘 | CYNTHIA LO MARGARET DC BRIAN KK | 2012 | JAMA2012，307，5： | 1 |
| 14 | Prevalence of skin disease among school children and adolescents in a Student Health Service Center in Hong Kong显示文摘 | Fung WK Lo KK | | 0，，06： | 1 |
| 15 | Simplifying hepatic venous outflow reconstruction in sequential living donor liver transplantation显示文摘 | Chan SC Lo CM Ng KK | 2009 | Liver Transpl2009，15，11： | 1 |
| 16 | 显示文摘 | Tang WY Lo KK Lam WY | 1995 | Br J Dermatol1995，133，3： | 1 |
| 17 | Breast and prostate cancer patients differ significantly in their serum Thymidine kinase1(TK1)specific activities compared with those hematological malignancies and blood donors:implications of using serum TK1 as a biomarker显示文摘 | Jagarlamudi KK Hansson LO Eriksson S | 2015 | BMC Cancer2015，，15： | 1 |
| 18 | Linkage and association of myocilin (MYOC) polymorphisms with high myopia in a Chinese population显示文摘 | Tang WC Yip SP Lo KK | 2007 | Mol Vis2007，13，： | 1 |
| 19 | Linkage and association of myocilin (MYOC) polymorphisms with high myopia in a Chinese population显示文摘 | Tang WC Yip SP Lo KK Ng PW Choi PS Lee SY | 2007 | Mol Vis2007，13，： | 1 |
| 20 | Gabapentin for complex regional pain syn-drome in Machado-Joseph disease: a case report 显示文摘 | Lo YC Liao KK Lee YC | 2011 | J MedCaseReports2011，5，1： | 1 |
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