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| 1 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 2 | Strategies to tackle the challenges of external beam radiotherapy for liver tumors显示文摘Primary and metastatic liver cancer is an increasingly common and difficult to control disease entity.Radiation offers a non-invasive treatment alternative for these patients who often have few options and a poor prognosis.However,the anatomy and aggressiveness of liver cancer poses significant challenges such as accurate localization at simulation and treatment,management of motion and appropriate selection of dose regimen.This article aims to review the options available and provide information for the practical implementation and/or improvement of liver cancer radiation programs within the context of stereotactic body radiotherapy and image-guided radiotherapy guidelines.Specific patient inclusion and exclusion criteria are presented given the significant toxicity found in certain sub-populations treated with radiation.Indeed,certain sub-populations,such as those with tumor thrombosis or those with larger lesions treated with transarterial chemoembolization,have been shown to have significant improvements in outcome with the addition of radiation and merit special consideration.Implementing a liver radiation programrequires three primary challenges to be addressed:(1) immobilization and motion management;(2) localization;and(3) dose regimen and constraint selection.Strategies to deal with motion include simple internal target volume(ITV) expansions,non-gated ITV reduction strategies,breath hold methods,and surrogate marker methods to enable gating or tracking.Localization of the tumor and organs-at-risk are addressed using contrast infusion techniques to take advantage of different normal liver and cancer vascular anatomy,imaging modalities,and margin management.Finally,a dose response has been demonstrated and dose regimens appear to be converging.A more uniform approach to treatment in terms of technique,dose selection and patient selection will allow us to study liver radiation in larger and,hopefully,multicenter randomized studies. | Michael I Lock Jonathan Klein Hans T Chung Joseph M Herman Edward Y Kim William Small Nina A Mayr Simon S Lo | 2017 | World Journal of Hepatology2017，9，14： | 2 |
| 3 | Characterization of silane-modified immobilized gold colloids as a substrate for surface-enhanced Raman spectroscopy显示文摘 | Olson L G Lo Y S Beebe T P | 2001 | Analytical Chemistry2001，73，： | 1 |
| 4 | Rapid clearance of fetal DNA from maternal plasma显示文摘 | Lo Y M Zhang J Leung T N | 1999 | Am J Hum Genet1999，64，： | 1 |
| 5 | Novel baculovirus DNA elements strongly stimulate activities of exogenous and endogenous promoters 显示文摘 | LO H R CHOU C C WU T Y | 2002 | The Journal of Biological Chemistry2002，277，7： | 1 |
| 6 | Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange(Citrus sinensis) peel显示文摘 | Li S Lo C Y Ho C T | 2006 | Journal of Agriculture Food Chemistry2006，54，： | 1 |
| 7 | Diaehronous uplift of the Tibetan Plateau starting 40 Myr ago显示文摘 | Chung S L Lo C H Lee T Y | 1998 | Nature1998，394，： | 1 |
| 8 | Reduced expression of APC and DCC gene protein in breast cancer显示文摘 | Ho K Y Kalle W H Lo T H | 1999 | Histopathology1999，35，3： | 1 |
| 9 | Microwave-hydrothermal decomposition of perfluorooctanoic acid in water by iron-activated persulfate oxidation显示文摘 | Lee Y C Lo S L Chiueh P T | | Water Research0，44，3： | 1 |
| 10 | Erythropoietin enhances endog- enous haem oxygenase-I and represses immune responses to amelio- rate experimental autoimmune encephalomyelitis 显示文摘 | Chen S J Wang Y L Lo W T | 2010 | Clin Exp Im- munol2010，162，2： | 1 |
| 11 | A high- efficiency dimmable LED driver for low-power lighting applications 显示文摘 | CHIU H J LO Y K CHEN J T | 2010 | IEEE Trans Indus Elec2010，57，2： | 1 |
| 12 | Determination of volatile organic compounds in workplace air by multisorbent adsorption/thermal desorption-GC/MS显示文摘 | WU C H FENG C T LO Y S | 2004 | Chemosphere2004，56，1： | 1 |
| 13 | Haptic feedback in teleoperation of multifingered robot hands显示文摘 | SHEN Y T LO W T LIU Y H | 2003 | Int J on Intelligent Automation and Soft Computing2003，，： | 1 |
| 14 | Single element rectangular microstrip antenna for dual-frequency operation显示文摘 | ZHONG S S LO Y T | 1983 | Electron Lett1983，19，8： | 1 |
| 15 | (3RK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood显示文摘 | Arnon T I Xu Y Lo C | 2011 | Science2011，333，6051： | 1 |
| 16 | Effect of external cephalic version at term on fetal circulation显示文摘 | LAU T K LEUNG T Y LO K W | 2000 | American Jour- nal of Obstetrics and Gynecology2000，182，5： | 1 |
| 17 | Adakites from continental collision zones: Melting of thickened lower crust beneath southern Tibet 显示文摘 | Chung S L Liu D Y Ji J Q Chu M F Lee H Y Wen D J Lo C H Lee T Y Qian Q Zhang Q | 2003 | Geology2003，31，11： | 1 |
| 18 | Hydroxylated polymethoxyflavones and methylated flavonoids in sweet orange (Citrus sinensis) peel 显示文摘 | Li S M Lo C Y Ho C T | 2006 | J Agri Food Chem2006，54，12： | 1 |
| 19 | A decision support framework for strategic purchasing显示文摘 | V H Y Lo R T McIvor | 2000 | Journal of Materials Processing Technology2000，，107： | 1 |
| 20 | A fuzzy indexmodel for trophic status evaluationof reservoirwaters 显示文摘 | Liou Y T Lo S L | 2005 | Water Research2005，39，7： | 1 |
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