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9篇 您的检索式:作者名="Loquai"
    题名 作者 年代 出处 被引量
1A randomised, phase II study ofintetumumab, an anti-av-integrin mAb, alone and with dacarbazine instage IV melanoma 显示文摘ODay S Pavlick A Loquai C 2011Br J Cancer2011,105,3:1
2Genomic correlates of response to CTLA-4 blockade in metastatic melanoma显示文摘Van Allen Eliezer M. Miao Diana Schilling Bastian Shukla Sachet A. Blank Christian Zimmer Lisa Sucker Antje Hillen Uwe Geukes Foppen Marnix H. Goldinger Simone M. Utikal Jochen Hassel Jessica C. Weide Benjamin Kaehler Katharina C. Loquai Carmen Mohr Peter 2015Science . 2015 (6257)2015,,6257:1
3Increased frequencies of CD1 lb(+) CD33(+) CD14(+) HLA-DR(Iow) myeloid-derived suppressor cells are an early event in melanoma patients 显示文摘Rudolph BM Loquai C Gerwe A 2014Exp Dermatol2014,23,3:1
4Quality of life in melanoma patients during adjuvant treatment with pegylated interferon-alpha 2b: patients' and doctors' views显示文摘Loquai C Schmidtmann I Beutel M 2011European journal of dermatology2011,21,6:1
5Increased frequencies of CD11b^+CD33^+CD14^+HLA-DR^low myeloid-derived suppressor cells are an early event in melanoma patients显示文摘Rudolph BM Loquai C Gerwe A 2014Exp Dermatol2014,23,3:1
6Anxiety, posttraumatic stress, and fear of canc- er progression in patients with melanoma in cancer after care 显示文摘Erim Y Loquai C 2013Oneologie2013,36,10:1
7Radiosensitization by BRAF inhibitor therapy mechanism and frequency of toxicity in melanoma patient显示文摘Hecht M Zimmer L Loquai C 2015Ann Oncol2015,26,6:1
8Liver-directed treatment is associated with improved survival and increased response to immune checkpoint blockade in metastatic uveal melanoma:results from a retrospective multicenter trial显示文摘Metastases of uveal melanoma(UM)spread predominantly to the liver.Due to low response rates to systemic therapies,liver-directed therapies(LDT)are commonly used for tumor control.The impact of LDT on the response to systemic treatment is unknown.A total of 182 patients with metastatic UM treated with immune checkpoint blockade(ICB)were included in this analysis.Patients were recruited from prospective skin cancer centers and the German national skin cancer registry(ADOReg)of the German Dermatologic Cooperative Oncology Group(DeCOG).Two cohorts were compared:patients with LDT(cohort A,n=78)versus those without LDT(cohort B,n=104).Data were analyzed for response to treatment,progression-free survival(PFS),and overall survival(OS).The median OS was significantly longer in cohort A than in cohort B(20.1 vs.13.8 months;P=0.0016)and a trend towards improved PFS was observed for cohort A(3.0 vs.2.5 months;P=0.054).The objective response rate to any ICB(16.7%vs.3.8%,P=0.0073)and combined ICB(14.1%vs.4.5%,P=0.017)was more favorable in cohort A.Our data suggest that the combination of LDT with ICB may be associated with a survival benefit and higher treatment response to ICB in patients with metastatic UM.Elias A.T.Koch Anne Petzold Anja Wessely Edgar Dippel Markus Eckstein Anja Gesierich Ralf Gutzmer Jessica C.Hassel Harald Knorr Nicole Kreuzberg Ulrike Leiter Carmen Loquai Friedegund Meier Markus Meissner Peter Mohr Claudia Pföhler Farnaz Rahimi Dirk Schadendorf Max Schlaak Kai-Martin Thoms Selma Ugurel Jochen Utikal Michael Weichenthal Beatrice Schuler-Thurner Carola Berking Markus V.Heppt 2023Frontiers of Medicine2023,17,5:0
9彩纸样皮损伴角化过度:一种新的紫外线诱导的色素减退性疾病Loquai C Metze D Nashan D M. Bhm 冯义国 周欣 2005世界核心医学期刊文摘(皮肤病学分册)2005,0,10:0
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