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| 1 | indocyanine green-based fluorescence imaging in visceral and hepatobiliary and pancreatic surgery:State of the art and future directions显示文摘In recent years, the use of fluorescence-guided surgery(FGS) to treat benign and malignant visceral, hepatobiliary and pancreatic neoplasms has significantly increased. FGS relies on the fluorescence signal emitted by injected substances(fluorophores) after being illuminated by ad hoc laser sources to help guide the surgical procedure and provide the surgeon with real-time visualization of the fluorescent structures of interest that would be otherwise invisible. This review surveys and discusses the most common and emerging clinical applications of indocyanine green(ICG)-based fluorescence in visceral, hepatobiliary and pancreatic surgery. The analysis, findings, and discussion presented here rely on the authors' significant experience with this technique in their medical institutions, an up-to-date review of the most relevant articles published on this topic between 2014 and 2018, and lengthy discussions with key opinion leaders in the field during recent conferences and congresses. For each application, the benefits and limitations of this technique, as well as applicable future directions, are described. The imaging of fluorescence emitted by ICG is a simple, fast,relatively inexpensive, and harmless tool with numerous different applications in surgery for both neoplasms and benign pathologies of the visceral and hepatobiliary systems. The ever-increasing availability of visual systems that can utilize this tool will transform some of these applications into the standard of care in the near future. Further studies are needed to evaluate the strengths and weaknesses of each application of ICG-based fluorescence imaging in abdominal surgery. | Gian Luca Baiocchi Michele Diana Luigi Boni | 2018 | World Journal of Gastroenterology2018，24，27： | 19 |
| 2 | Effect of perioperative blood transfusion on clinical outcomes in hepatic surgery for cancer显示文摘Allogeneic blood transfusion during liver resection for malignancies has been associated with an increased incidence of different types of complications: infectious complications, tumor recurrence, decreased survival. Even if there is clear evidence of transfusion-induced immunosuppression, it is difficult to demonstrate that transfusion is the only determinant factor that decisively affects the outcome. In any case there are several motivations to reduce the practice of blood transfusion. The advantages and drawbacks of different transfusion alternatives are reviewed here, emphasizing that surgeons and anesthetists who practice in centers with a high volume of liver resections, should be familiar with all the possible alternatives. | Gianlorenzo Dionigi Luigi Boni Francesca Rovera Stefano Rausei Salvatore Cuffari Giovanni Cantone Alessandro Bacuzzi Renzo Dionigi | 2009 | World Journal of Gastroenterology2009，15，32： | 10 |
| 3 | 胃的癌症的多模式的治疗显示文摘 Gastric cancer is the second leading cause of death from malignant disease worldwide.Although complete surgical resection remains the only curative modality for early stage gastric cancer,surgery alone only provides long-term survival in 20%of patients with advancedstage disease.To improve current results,it is necessary to consider multimodality treatment,including chemotherapy,radiotherapy and surgery.Recent clinical trials have shown survival benefit of combining different neoadjuvant or adjuvant protocols compared with surgery with curative intent.Furthermore,the implementation of chemotherapy with novel targeted agents could play an important role in the multimodal management of advanced gastric cancer.In this paper,we focus on a multidisciplinary approach in the treatment of gastric cancer and discuss future strategies to improve the outcome for these patients. | Ilaria Proserpio Stefano Rausei Sabrina Barzaghi Francesco Frattini Federica Galli Domenico Iovino Francesca Rovera Luigi Boni Gianlorenzo Dionigi Graziella Pinotti | 2014 | World Journal of Gastrointestinal Surgery2014，6，4： | 8 |
| 4 | seventh tumor-node-metastasis staging of gastric cancer: Five-year follow-up显示文摘Seventh tumor-node-metastasis(TNM) classification for gastric cancer,published in 2010,introduced changes in all of its three parameters with the aim to increase its accuracy in prognostication. The aim of this review is to analyze the efficacy of these changes and their implication in clinical practice. We reviewed relevant Literature concerning staging systems in gastric cancer from 2010 up to March 2016. Adenocarcinoma of the esophago-gastric junction still remains a debated entity,due to its peculiar anatomical and histological situation: further improvement in its staging are required. Concerning distant metastases,positive peritoneal cytology has been adopted as a criterion to define metastatic disease: however,its search in clinical practice is still far from being routinely performed,as staging laparoscopy has not yet reached wide diffusion. Regarding definition of T and N: in the era of multimodal treatment these parameters should more influence both staging and surgery. The changes about T-staging suggested some modifications in clinical practice. Differently,many controversies on lymph node staging are still ongoing,with the proposal of alternative classification systems in order to minimize the extent of lymphadenectomy. The next TNM classification should take into account all of these aspects to improve its accuracy and the comparability of prognosis in patients from both Eastern and Western world. | Stefano Rausei Laura Ruspi Federica Galli Vincenzo Pappalardo Giuseppe Di Rocco Francesco Martignoni Francesco Frattini Francesca Rovera Luigi Boni Gianlorenzo Dionigi | 2016 | World Journal of Gastroenterology2016，22，34： | 2 |
| 5 | In advanced gastric cancer:Prognosis and treatment of patients with positive peritoneal cytology显示文摘Positive peritoneal cytology in gastric cancer is classified as M1 disease by the 7thEdition of American Joint Committee on Cancer staging system.With the introduction of laparoscopy and peritoneal washing cytology in the staging of gastric cancer a new category of patients has been identified.These are patients with no macroscopic peritoneal metastases but with peritoneal cytology positive(P0C1).Prognosis and treatment of such patientsrepresent a controversial issue.We evaluate the state of the art of staging system in gastric cancer and discusss tandardisation in staging and treatment procedures.There is still a lack of uniformity in the use of laparoscopy with peritoneal cytology in clinical decision making and in the surgical treatment for gastric cancer.Survival of this patient subset remains poor.Multimodal therapies and new therapeutic strategies are required to improve the survival of these patients. | Francesco Frattini Stefano Rausei Corrado Chiappa Francesca Rovera Luigi Boni Gianlorenzo Dionigi | 2013 | World Journal of Gastrointestinal Surgery2013，5，5： | 2 |
| 6 | The safety of energy-based devices in open thyroidectomy: a prospective, randomised study comparing the LigaSure? (LF1212) and the Harmonic? FOCUS显示文摘 | Gianlorenzo Dionigi Luigi Boni Stefano Rausei Francesco Frattini Cesare Ferrari Alberto Mangano Andrea Leotta Marco Franchin | 2012 | Langenbeck’s Archives of Surgery2012，，5： | 2 |
| 7 | Neuroendocrine carcinomas of the breast显示文摘 | Francesca Rovera Patrizia Masciocchi Alessandra Coglitore Stefano La Rosa Gianlorenzo Dionigi Marina Marelli Luigi Boni Renzo Dionigi | 2008 | International Journal of Surgery2008，，： | 1 |
| 8 | A decade in gastric cancer curative surgery:Evidence of progress(1999-2009)显示文摘To investigate the progress in evidence-based surgical treatment of non-metastatic gastric cancer,we re- viewed the last ten years'literature.The data used in this review were identified by searches made on MED-LINE,Current Contents,PubMed,and other references taken from relevant original articles(on prospective and retrospective studies)concerning gastric cancer surgery.Only papers published in English between January 1999 and December 2009 were selected.Data from ongoing studies were obtained in December 2009, from the trials registry of the United States National Institutes of Health(http://gffzzdbf2e3d08f4046d0hbwx0wcnnfok966n0.ffgz.tsg.suse.edu.cn).The citations list was presented according to evidence based relevance(i.e.,randomized controlled trials,pro- spective studies,retrospective series).In the last ten years,many challenges have been faced relating to the extension of gastric resection and nodal dissection as well as surgical timing,but we found only limited evidence,regardless of latitude of study.The ongoing phase-Ⅲ trials may provide answers that will be valid for the coming decades,and which may bring definitive answers for the currently unresolved questions. | Stefano Rausei Gianlorenzo Dionigi Francesca Rovera Luigi Boni Caterina Valerii Luisa Giavarini Francesco Frattini Renzo Dionigi | 2012 | World Journal of Gastrointestinal Surgery2012，4，3： | 1 |
| 9 | DNA methylation patterns in blood of patients with colorectal cancer and adenomatous colorectal polyps显示文摘 | Elisa Cassinotti Joshua Melson Thomas Liggett Anatoliy Melnikov Qilong Yi Charles Replogle Sohrab Mobarhan Luigi Boni Sergio Segato Victor Levenson | 2011 | Int. J. Cancer2011，，5： | 1 |
| 10 | Single incision laparoscopic right colectomy显示文摘 | Luigi Boni Gianlorenzo Dionigi Elisa Cassinotti Matteo Di Giuseppe Mario Diurni Stefano Rausei Fabrizio Cantore Renzo Dionigi | 2010 | Surgical Endoscopy2010，，12： | 1 |
| 11 | The double-orifice technique in mitral valve repair: A simple solution for complex problems显示文摘 | Ottavio Alfieri Francesco Maisano Michele De Bonis Pier Luigi Stefano Lucia Torracca Michele Oppizzi Giovanni La Canna | 2001 | The Journal of Thoracic and Cardiovascular Surgery2001，，4： | 1 |
| 12 | Gastrointestinal stromal tumors—frequency, malignancy, and new prognostic factors: The experience of a single institution显示文摘 | Valentina Bertolini Anna Maria Chiaravalli Catherine Klersy Claudia Placidi Silvia Marchet Luigi Boni Carlo Capella | 2007 | Pathology - Research and Practice2007，，4： | 1 |
| 13 | Refining sorafenib therapy: lessons from clinical practice显示文摘 | Luigi Bolondi Antonio Craxi Franco Trevisani Bruno Daniele Giovan Giuseppe Di Costanzo Stefano Fagiuoli Calogero Cammà Paolo Bruzzi Romano Danesi Federico Spandonaro Corrado Boni Armando Santoro Massimo Colombo | 2015 | Future Oncol2015，，3： | 1 |
| 14 | Single-Port Laparoscopic Spleen Preserving Distal Pancreatectomy显示文摘 | Stephen K. Y. Chang Davide Lomanto Maria Mayasari Luigi Boni | 2012 | Minimally Invasive Surgery2012，，： | 1 |
| 15 | Neuromonitoring and video-assisted thyroidectomy: a prospective, randomized case-control evaluation显示文摘 | Gianlorenzo Dionigi Luigi Boni Francesca Rovera Alessandro Bacuzzi Renzo Dionigi | 2009 | Surgical Endoscopy2009，，5： | 1 |
| 16 | Neuromonitoring and video-assisted thyroidectomy: a prospective, randomized case-control evaluation显示文摘 | Gianlorenzo Dionigi Luigi Boni Francesca Rovera Alessandro Bacuzzi Renzo Dionigi | 2009 | Surgical Endoscopy2009，，： | 1 |
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