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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Operational space trajectory tracking control of robot manipulators endowed with a primary controller of synthetic joint velocity 显示文摘 | Javier M V Luis G H | 2011 | ISATransactions(S0019-0578)2011，50，： | 1 |
| 3 | Dynamic Buckling of Anchored Steel Tanks Subjected to Horizontal Earthquake Excitation 显示文摘 | Juan C V Luis A G Luis E S | 2006 | Journal of Constructional Steel Research2006，62，6： | 1 |
| 4 | A validated solid - liquid extraction method for the HPLC determination of polyphenols in apple tissues Comparison with pressurised liquid extraction显示文摘 | ROSA M ALEJANDRO B EDURNE C LUIS A BLANCA G FRANCISCA V | 2005 | Talanta2005，，65： | 1 |
| 5 | Adherence pili of pathogenic srains of avian Escherichia coli显示文摘 | Helio R N Marilda C V Luis C J G | 1997 | Veterinary Microbiology1997，59，： | 1 |
| 6 | Epicuticular wax content and mor- phology as related to ethylene and storage performance of 'Navelate~ orange fruit显示文摘 | Jacques F C Luis G C Ana V | 2010 | Postharvest Biology and Technology2010，55，： | 1 |
| 7 | Acute and chron- ic toxicities of Irgarol alone and in combination with copper to the marine copepod Tigriopus japonicas 显示文摘 | Bao V W Leung K M Lui G C | 2013 | Chemosphere2013，90，3： | 1 |
| 8 | Rejection after conversion to a proliferation signal inhibitor in chronic heart transplantation显示文摘 | Francisco González‐Vílchez José A. Vázquez de Prada María J. Paniagua Luis Almenar Sonia Mirabet Manuel Gómez‐Bueno Beatriz Díaz‐Molina Jose M. Arizón Juan Delgado Félix Pérez‐Villa María G. Crespo‐Leiro Luis Martínez‐Dolz Eulalia Roig Javier Segovia José | 2013 | Clin Transplant2013，，6： | 1 |
| 9 | Wireless-control strategy for parallel operation of distributed-generation inverters显示文摘 | Guerrero J M Matas J Luis G D V | 2006 | IEEE Transactions on Industrial Electronics2006，53，5： | 1 |
| 10 | Output impedance design of parallel-connected UPS inverters with wireless load-sharing control显示文摘 | Guerrero J M Luis G De V L Matas J | 2005 | IEEE Transactions on Industrial Electronics2005，52，4： | 1 |
| 11 | Cooperation mechanism taxonomy for wireless sensor and actor networks显示文摘 | Erica R I Luis V G | | 0，，01： | 1 |
| 12 | An ontology-based approach for evaluating the domain appropriateness and comprehensibility appropriateness of modeling languages显示文摘 | GIANCARLO G LUIS F MARTEN V | | 0，，01： | 1 |
| 13 | Outputimpendance design of parallel-connected UPSinverters with wireless load-sharing control 显示文摘 | GUERRERO J M LUIS G de V MATAS J | 2005 | IEEE Trans on Industry Electronics2005，52，4： | 1 |
| 14 | Association of MHC class I related gene B (M I CB)to celiac disease显示文摘 | Segundo G Luis R Antonio L V | 2004 | Am J Gastroenterol2004，99，4： | 1 |
| 15 | Feedback linearization of a single-phase active power filter via sliding mode control显示文摘 | JoséM Luis G V Jaume M | 2008 | IEEE Trans on Power Electronic2008，23，1： | 1 |
| 16 | Operational space trajectory tracking control of robot manipulators endowed with a primary controller of synthetic joint velocity 显示文摘 | Javier M V Luis G H | 2011 | ISATransactions(S0019-0578)2011，50，1： | 1 |
| 17 | Pareto-adaptive ε-dominance显示文摘 | Alfredo G Hernández-Díaz Luis V Santana-Quintero | | 0，，04： | 1 |
| 18 | Robust support vector method for hyperspectral data classification and knowledge discovery显示文摘 | Custavo C V Luis G C Javier C M | 2004 | IEEE Transactions on Geoscience and Remote Sensing2004，42，7： | 1 |
| 19 | DEMORS:A hybrid multi- objective optimization algorithm using differential evolution and rough theory for constrained problems 显示文摘 | Luis V Santana- Quintero Alfredo G Hernandez- Diaz Julian Monlina | 2010 | Computers & Operations Research2010，37，： | 1 |
| 20 | A dherence pill of pathogenic strains of avian Escherichia coli显示文摘 | HELLO R N MARILDA C V LUIS C J G | 1997 | Veterinary Microbiology1997，59，： | 1 |
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