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| 1 | Early infant male circumcision:Systematic review,risk-benefit analysis,and progress in policy显示文摘AIM To determine whether recent evidence-based United States polices on male circumcision(MC) apply to comparable Anglophone countries,Australia and New Zealand.METHODS Articles in 2005 through 2015 were retrieved from PubM ed using the keyword 'circumcision' together with 36 relevant subtopics.A further PubM ed search was performed for articles published in 2016.Searches of the EMBASE and Cochrane databases did not yield additional citable articles.Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further.The most relevant andrepresentative of the topic were included.Bibliographies were examined to retrieve further key references.Randomized controlled trials,recent high quality systematic reviews or meta-analyses(level 1++ or 1+ evidence) were prioritized for inclusion.A risk-benefit analysis of articles rated for quality was performed.For efficiency and reliability,recent randomized controlled trials,metaanalyses,high quality systematic reviews and large welldesigned studies were used if available.Internet searches were conducted for other relevant information,including policies and Australian data on claims under Medicare for MC.RESULTS Evidence-based policy statements by the American Academy of Pediatrics(AAP) and the Centers for Disease Control and Prevention(CDC) support infant and later age male circumcision(MC) as a desirable public health measure.Our systematic review of relevant literature over the past decade yielded 140 journal articles that met our inclusion criteria.Together,these showed that early infant MC confers immediate and lifelong benefits by protecting against urinary tract infections having potential adverse long-term renal effects,phimosis that causes difficult and painful erections and 'ballooning' during urination,inflammatory skin conditions,inferior penile hygiene,candidiasis,various sexually transmissible infections in both sexes,genital ulcers,and penile,prostate and cervical cancer.Our risk-benefit analysis showed that benefits exceeded procedural risks,which are predominantly minor,by up to 200 to 1.We estimated that more than 1 in 2 uncircumcised males will experience an adverse foreskin-related medical condition over their lifetime.Wide-ranging evidence from surveys,physiological measurements,and the anatomical location of penile sensory receptors responsible for sexual sensation strongly and consistently suggested that MC has no detrimental effect on sexual function,sensitivity or pleasure.United States studies showed that early infant MC is cost saving.The evidence supporting early infant MC has further strengthened since the positive AAP and CDC reviews.CONCLUSION Affirmative MC policies are needed in Australia and New Zealand.Routine provision of accurate,unbiased education,and access in public hospitals,will maximize health and financial benefits. | Brian J Morris Sean E Kennedy Alex D Wodak Adrian Mindel David Golovsky Leslie Schrieber Eugenie R Lumbers David J Handelsman John B Ziegler | 2017 | World Journal of Clinical Pediatrics2017，6，1： | 2 |
| 2 | Measurement of baroreceptor-mediated effects on heart rate variability in fetal显示文摘 | Lumbers ER Yu ZY | 1999 | J Physiol Lond1999，515，2： | 1 |
| 3 | Nephrin-a biomark- er of early glomerular injury显示文摘 | Kandasamy Y Smith R Lumbers E R | 2014 | Biomark Res2014，2，： | 1 |
| 4 | Globalisation and food consump- tion in tourism显示文摘 | IMak A H N Lumbers M Eves A | 2011 | Annals of Tourism Research2011，39，1： | 1 |
| 5 | Factors influencing touristfood consumption显示文摘 | MakA H N Lumbers M Eves A | 2012 | International Journal of Hospitality Manage-ment2012，31，3： | 1 |
| 6 | Globalisation and food consump-tion in tourism显示文摘 | MakA H N Lumbers M Eves A | 2012 | Annals of Tourism Research2012，39，1： | 1 |
| 7 | Food choice and secondary school meals: the nutritional implications of choices based on preference rather than perceived healthiness 显示文摘 | Noble C Comey M Eves A Kipps M Lumbers M | 2003 | International Journal of Hospitality Management2003，22，： | 1 |
| 8 | Effects of placental in- sufficiency on the ovine fetal renin-angiotensin system 显示文摘 | Zhang DY Lumbers ER Simonetta G | 2000 | Exp Physio12000，85，1： | 1 |
| 9 | Adrenergic nervous system in heart failure 显示文摘 | Esler M Kaye D Lumbere G | 1997 | Am J Cardiol1997，80，： | 1 |
| 10 | Building bridges the clinical nurse special- ist consultant role in improving diabetes self- Management educa- tion and support for medically underserved populations 显示文摘 | Crowther JQ Lumber T | 2014 | AADE in Practice2014，2，1： | 1 |
| 11 | Effects of losartan on the cardio-vascular system,renal heamodynamics and function and lung liquid flow in fetal sheep 显示文摘 | Stevenson KM Gibson KJ Lumbers ER | 1996 | Clin Exp Pharmacol Physiol1996，23，： | 1 |
| 12 | Interactions between AT1 and AT2 receptors in uterine arteries from pregnant ewes 显示文摘 | McMullen JR Gibson KJ Lumbers ER | 1999 | Eur J Pharmacol1999，378，2： | 1 |
| 13 | Inhibition by angiotensinⅡof baroreceptor-evoked activity in vagal efferent nerves in the dog显示文摘 | Lumbers ER McCloskey DI Potter ER | 1979 | J Physiol1979，294，： | 1 |
| 14 | Globalization and food con- sumption in tourism显示文摘 | Mak A H N Lumbers M Eves A | 2012 | Annals of Tourism Research2012，39，1： | 1 |
| 15 | Nutritional status in elderly female hip fracture patients:comparison with an age-matched home living group attending day centres显示文摘 | Lumbers M New SA Gibson S | | 0，，： | 1 |
| 16 | Leakage Reduction in water distribution systems: optimal valve control 显示文摘 | Kalanithy Vairavamoorthy Jeremy Lumbers | 1998 | Hydraulic Engineering1998，124，11： | 1 |
| 17 | CODE-EHR:临床研究中运用结构化电子医疗记录的最佳实践框架显示文摘改善患者生存质量是全球临床医学的发展目标,大数据是实现其发展的关键所在。技术进步使结构化电子医疗记录得以常规化,也可能会改善缺失重要临床证据的问题。虽然大数据及其相关分析在新冠大流行期间发挥了重要作用,但也存在严重的缺陷。证实、核验、数据隐私以及对科学研究社会责任的践行是一项重要挑战。欧洲心脏病协会和BigData@Heart联盟已经收集了包括患者代表、临床医生、科研人员、监管机构、期刊编辑和企业代表在内的多元化国际参与者,提出了CODE-EHR的最低标准框架。为改进研究设计、提高信息透明度提供方法手段,同时为实现医疗保健数据的稳健并能够有效运用制定了技术路线图。 | Dipak Kotecha Folkert W Asselbergs Stephan Achenbach Stefan DAnker Dan Atars Colin Baigent Amitava Banerjee Birgit Beger Cunnar Brobert Barbara Casadei Cinzia Ceccarelli Martin R Cowie Filippo Crea Maureen Cronin Spiros Denaxas Andrea Derix Donna Fitzsimons Martin Fredriksson Chris PGale Georgios V Ckoutos Wim Goettsch Harry Hemingway Martin Ingvaris Adrian Jonas's Robert Kazmierski Susanne Logstrup R Thomas Lumbers Thomas F Lischer Paul McGreavy leana L Pina Lothar Roesiga Carl Steinbeisser Mats Sundgren Benoit Tyl Chislaine van Thiel Kees van Bochove Panos EVardas Tiago Villanueva Marilena Vrana Wim Weber Franz Weidinger Stephan Windecker Angela Wood Diederick E Grobbee 创新药物计划BigData@Heart联盟 欧洲心脏病协会 CODE-EHR国际共识小组 宋奇繁(译) 汪奕名(译) | 2022 | 英国医学杂志中文版2022，25，12： | 0 |
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