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| 1 | Pioglitazone, a specific ligand of peroxisome proliferator-activated receptor-gamma, protects pancreas against acute cerulein-induced pancreatitis显示文摘ABM: To determine the effect of pioglitazone, a specific peroxisome proliferator-activated receptor-γ(PPARγ) ligand, on the development of acute pancreatitis (AP) and on the expression of heat shock protein 70 (HSP70) in the pancreas. METHODS: AP was induced in rats by subcutaneous infusion of cerulein for 5 h. Pancreatic blood flow was measured by laser Doppler flowmetry. Plasma lipase activity, interleukin-1β (IL-1β) and IL-10 were determined, Pancreatic weight and histology were evaluated and pancreatic DNA synthesis and blood flow as well as pancreatic mRNA for IL-1β and HSP70 were assessed in rats treated with pioglitazone alone or in combination with cerulein. RESULTS: Pioglitazone administered (10-100 mg/kg i.g.) 30 min before cerulein, attenuated dose-dependently the pancreatic tissue damage in cerulein-induced pancreatitis (CIP) as demonstrated by the improvement of pancreatic histology, reduction in plasma lipase activity, plasma concentration of pro-inflammatory IL-1β and its gene expression in the pancreas and attenuation of the pancreatitis-evoked fall in pancreatic blood flow. CIP increased pancreatic HSP70 mRNA and protein expression in the pancreas and this effect was enhanced by pioglitazone treatment. CONCLUSION: Pioglitazone attenuates CIP and the beneficial effect of this pioglitazone is multifactorial probably due to its anti-inflammatory activities, to the suppression of IL-1β and to the over-expression of HSP70. PPARγ ligands could represent a new therapeutic option in the treatment of AP. | Peter C Konturek Artur Dembinski Zygmunt Warzecha Grzegorz Burnat Piotr Ceranowicz Eckhart G Hahn Marcin Dembinski Romana Tomaszewska Stanislaw J Konturek | 2005 | World Journal of Gastroenterology2005，11，40： | 7 |
| 2 | Ischemic preconditioning inhibits development of edematous cerulein-induced pancreatitis: Involvement of cyclooxygenases and heat shock protein 70显示文摘AIM: To determine whether ischemic preconditioning (IP)affects the development of edematous cerulein-induced pancreatitis and to assess the role of cyclooxygenase-1 (COX-1), COX-2, and heat shock protein 70 (HSP 70) in this process.METHODS: In male Wistar rats, IP was performed by damping of celiac artery (twice for 5 min at 5-min intervals).Thirty minutes after IP or sham operation, acute pancreatitis was induced by cerulein. Activity of COX-1 or COX-2 was inhibited by resveratrol or rofecoxib, respectively (10 mg/kg).RESULTS: IP significantly reduced pancreatic damage in cerulein-induced pancreatitis as demonstrated by the improvement of pancreas histology, reduction in serum lipase and poly-C ribonuclease activity, and serum concentration of pro-inflammatory interleukin (IL)-1β.Also, IP attenuated the pancreatitis-evoked fall in pancreatic blood flow and pancreatic DNA synthesis.Serum level of anti-inflammatory IL-10 was not affected by IP. Cerulein-induced pancreatitis and IP increased the content of HSP 70 in the pancreas. Maximal increase in HSP 70 was observed when IP was combined with cerulein-induced pancreatitis. Inhibition of COXs, especially COX-2, reduced the protective effect of IP in edematous pancreatitis.CONCLUSION: Our results indicate that IP reduces pancreatic damage in cerulein-induced pancreatitis and this effect, at least in part, depends on the activity of COXs and pancreatic production of HSP 70. | Zygmunt Warzecha Artur Dembinski Piotr Ceranowicz Stanislaw J Konturek Marcin Dembinski Wieslaw W Pawlik Romana Tomaszewska Jerzy Stachura Beata Kusnierz-Cabala Jerzy W Naskalski Peter C Konturek | 2005 | World Journal of Gastroenterology2005，11，38： | 2 |
| 3 | Naming and outline of Dothideomycetes-2014 including proposals for the protection or suppression of generic names显示文摘Article 59.1,of the International Code of Nomenclature for Algae,Fungi,and Plants(ICN;Melbourne Code),which addresses the nomenclature of pleomorphic fungi,became effective from 30 July 2011.Since that date,each fungal species can have one nomenclaturally correct name in a particular classification.All other previously used names for this species will be considered as synonyms.The older generic epithet takes priority over the younger name.Any widely used younger names proposed for use,must comply with Art.57.2 and their usage should be approved by the Nomenclature Committee for Fungi(NCF).In this paper,we list all genera currently accepted by us in Dothideomycetes(belonging to 23 orders and 110 families),including pleomorphic and nonpleomorphic genera.In the case of pleomorphic genera,we follow the rulings of the current ICN and propose single generic names for future usage.The taxonomic placements of 1261 genera are listed as an outline.Protected names and suppressed names for 34 pleomorphic genera are listed separately.Notes and justifications are provided for possible proposed names after the list of genera.Notes are also provided on recent advances in our understanding of asexual and sexual morph linkages in Dothideomycetes.A phylogenetic tree based on four gene analyses supported 23 orders and 75 families,while 35 families still lack molecular data. | Nalin N.Wijayawardene Pedro W.Crous Paul M.Kirk David L.Hawksworth Saranyaphat Boonmee Uwe Braun Dong-Qin Dai Melvina J.D’souza Paul Diederich Asha Dissanayake Mingkhuan Doilom Singang Hongsanan E.B.Gareth Jones Johannes Z.Groenewald Ruvishika Jayawardena James D.Lawrey Jian-Kui Liu Robert Lücking Hugo Madrid Dimuthu S.Manamgoda Lucia Muggia Matthew P.Nelsen Rungtiwa Phookamsak Satinee Suetrong Kazuaki Tanaka Kasun M.Thambugala Dhanushka N.Wanasinghe Saowanee Wikee Ying Zhang Andre Aptroot H.A.Ariyawansa Ali H.Bahkali D.Jayarama Bhat Cécile Gueidan Putarak Chomnunti G.Sybren De Hoog Kerry Knudsen Wen-Jing Li Eric H.C.McKenzie Andrew N.Miller Alan J.L.Phillips Marcin Piatek Huzefa A.Raja Roger S.Shivas Bernad Slippers Joanne E.Taylor Qing Tian Yong Wang Joyce H.C.Woudenberg Lei Cai Walter M.Jaklitsch Kevin D.Hyde | 2014 | Fungal Diversity2014，，6： | 2 |
| 4 | Usefulness of Intrao perative Magnetic Resonance Ventriculography During Endoscopic Third Ventriculostomy显示文摘 | Pawel T Marcin C Pawel S | 2013 | Neurosurgery2013，73，4： | 1 |
| 5 | Near infrared spectroscopy: a tool for chemical properties and organic matter assessment of afforested mine soils显示文摘 | MARCIN P MARCIN C | 2014 | Ecological Engineering2014，62，： | 1 |
| 6 | Mitsunobu reaction of n-alkyl and n-aeyl sulfonamides-an efficient route to protected amines 显示文摘 | Henry J R Marcin L R MeIntosh M C | 1989 | Tetrahedron Lett1989，30，： | 1 |
| 7 | High-performance liquid chromatography method for the simultaneous determination of thiamine hydrochloride, pyridoxine hydrochloride and cyanocobalamin in pharmaceutical formulations using coulometric electrochemical and ultraviolet detection显示文摘 | MARCIN L M ANNA L WOJCIECH C | 2005 | J Chromatogr: A2005，1094，： | 1 |
| 8 | Processing,microstructure andmechanical properties of Al2O3-Cr nanocomposites显示文摘 | MARCIN C KATARZYNA P | 2007 | Journal ofthe European Ceramic Society2007，27，23： | 1 |
| 9 | Histological and histochemical assessment of the effects of a single dose adriamycin on fetal rat kidney显示文摘 | AGNIESZKA P MARCIN W KRYSTYNA C | 2005 | Acta Histochemica2005，107，2： | 1 |
| 10 | Frangogiannis Transforming growth factor(TGF)-βsignaling in cardiac remodeling显示文摘 | Marcin D Wei C Nikolaos G | 2011 | J Mol Cell Cardiol2011，51，4： | 1 |
| 11 | Prevalence of au- tism spectrum disorders in guanajuato, Mexico: the leon survey显示文摘 | FOMBONNE E MARCIN C MANERO A C | 2016 | J Autism Dev Disord2016，46，5： | 1 |
| 12 | Quantitative comparison of open reduction and internal fixation versus the gillies method in the treatment of orbitozygomatic complex fractures 显示文摘 | Marcin C Mark M Chen L | 2005 | Plast Reconstr Surg2005，115，7： | 1 |
| 13 | Adiponectin-an adipokine with unique metabolic properties显示文摘 | Andrzej W Marcin A Jerzy C | 2007 | Nephrol Dial Transplant2007，22，： | 1 |
| 14 | Processing, microstmcture and mechanical properties of Al2 O3 -Cr nanocomposites 显示文摘 | Marcin C | 2006 | Journal of the European Ceramic Society2006，25，9： | 1 |
| 15 | The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APP SW mice显示文摘 | Jerzy Wegiel Kuo-Chiang Wang Humi Imaki Richard Rubenstein Anetta Wronska Marcin Osuchowski William J Lipinski Larry C Walker Harry LeVine | 2001 | Neurobiology of Aging2001，，1： | 1 |
| 16 | Cryopreservation of embryogenic tissues of Picea omorika (Serbian spruce)显示文摘 | Teresa HP Pawe? C Marcin M Krystyna B | 2010 | Plant Cell Tissue Organ Cult2010，102，1： | 1 |
| 17 | The effect of IL-2, IL-12 and ILl5 on the function of natural killer cells in children suffering from type 1 diabetes mellitus显示文摘 | Awomir C Ewa P Marcin M | 2013 | Pediatric Endocrinology Diabetes & Metabolism2013，19，： | 1 |
| 18 | Near infrared spectroscopy:A tool for chemical properties and organic matter assessment of afforested mine soils显示文摘 | Marcin P Marcin C | 2014 | Ecological Engineering2014，62，： | 1 |
| 19 | Combined distiller waste utilisation and combustion gases desulphurisation method:The case study of soda-ash industry显示文摘 | Tomasz K Roman B Marcin C | 2007 | Conservation and Recycling2007，51，： | 1 |
| 20 | Hierarchies of Belief and Interim Rationalizability 显示文摘 | J C Ely Marcin Peski | 2005 | Theoretical Eonomics2005，，： | 1 |
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